Protein: Q6QU65
ADAM metalloprotease (Meltrin, isoform C (EC 3.4.24.-))

Gene: Q6QU65, Meltrin
Organism: Drosophila melanogaster
Interactions: 159
UniProt ID: Q6QU65

Gene Ontology (top 5):
GO:0004222 - metalloendopeptidase activity
GO:0006509 - membrane protein ectodomain proteolysis
GO:0016020 - membrane
GO:0042802 - identical protein binding
GO:0046872 - metal ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1246618

Q9VY33
Defective proboscis extension response 8, isoform A

1

3

High-throughput

0.559

High

1246592

Q9VK22
KEKKON4

1

5

High-throughput

0.514

High

1246604

Q9VT89
Insulin-like growth factor-binding protein complex acid labile subunit

1

0

High-throughput

0.481

High

1202440

Q59E38
FI03911p

1

0

High-throughput

0.464

High

1230946

PTK7
Tyrosine-protein kinase-like otk

1

11

High-throughput

0.445

High

1246536

Y0417
Probable protein phosphatase CG10417

1

1

High-throughput

0.445

High

1246537

Q7KN04
Spondin-1

1

7

High-throughput

0.445

High

1246542

MICAL
[F-actin]-monooxygenase Mical

1

2

High-throughput

0.445

High

235110

O46231
FI18705p1

1

2

High-throughput

0.442

High

458042

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

1

High-throughput

0.442

High

1246624

NU301
Nucleosome-remodeling factor subunit NURF301

1

5

High-throughput

0.442

High

583636

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.426

High

657752

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

0

High-throughput

0.426

High

1246528

Q76NQ3
Utx histone demethylase, isoform B

1

0

High-throughput

0.426

High

1246593

Q9VK56
ABC-type glutathione-S-conjugate transporter

1

0

High-throughput

0.426

High

1246626

Q9W0Z5
LP09747p

1

0

High-throughput

0.426

High

1246629

Q9W2Y4
RNA-binding protein NOB1

1

0

High-throughput

0.426

High

1246637

Q9W4R7
GH25737p

1

0

High-throughput

0.426

High

1246641

Q9XZS9
DNA 5'-3' helicase

1

0

High-throughput

0.426

High

56123

APKC
Atypical protein kinase C

1

1

High-throughput

0.407

High

197763

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

High-throughput

0.407

High

263576

FLOT1
Flotillin-1

1

2

High-throughput

0.407

High

264598

KPYK
Pyruvate kinase

1

1

High-throughput

0.407

High

358483

ADH
Alcohol dehydrogenase

1

2

High-throughput

0.407

High

598296

LAR
Tyrosine-protein phosphatase Lar

1

6

High-throughput

0.407

High

599454

KAPC3
cAMP-dependent protein kinase catalytic subunit 3

1

1

High-throughput

0.407

High

663965

PHB1
Prohibitin 1

1

4

High-throughput

0.407

High

725832

PDM1
Protein nubbin

1

1

High-throughput

0.407

High

821833

PSA2
Proteasome subunit alpha type-2

1

1

High-throughput

0.407

High

823762

SQH
Myosin regulatory light chain sqh

1

1

High-throughput

0.407

High

861434

KL61
Kinesin-like protein Klp61F

1

3

High-throughput

0.407

High

958859

ARF1
ADP-ribosylation factor 1

1

2

High-throughput

0.407

High

1069683

Q0E917
FI18818p1

1

20

High-throughput

0.407

High

1173414

CUL1
Cullin homolog 1

1

6

High-throughput

0.407

High

1175677

XPC
DNA repair protein complementing XP-C cells homolog

1

7

High-throughput

0.407

High

1191641

Q3YMU0
Protein disulfide-isomerase

1

4

High-throughput

0.407

High

1246529

Q7JV09
GH28348p

1

2

High-throughput

0.407

High

1246530

Q7JXU4
Nucleolar GTP-binding protein 2

1

2

High-throughput

0.407

High

1246531

Q7JY07
Glyceraldehyde-3-phosphate dehydrogenase

1

1

High-throughput

0.407

High

1246532

BOP1
Ribosome biogenesis protein BOP1 homolog

1

1

High-throughput

0.407

High

1246534

NO66
Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66

1

2

High-throughput

0.407

High

1246539

Q7KV88
Mitogen-activated protein kinase kinase kinase kinase

1

1

High-throughput

0.407

High

1246540

Q7KVA7
Dynein heavy chain at 62B

1

2

High-throughput

0.407

High

1246541

Q7KVC9
FI04445p

1

1

High-throughput

0.407

High

1246545

Q8IPN1
Transforming acidic coiled-coil protein, isoform A

1

2

High-throughput

0.407

High

1246548

SPEN
Protein split ends

1

1

High-throughput

0.407

High

1246549

CAPON
Capon-like protein

1

1

High-throughput

0.407

High

1246551

Q95TJ6
LP01469p

1

20

High-throughput

0.407

High

1246553

Q95TU2
LD23187p

1

1

High-throughput

0.407

High

1246554

Q960K8
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial

1

1

High-throughput

0.407

High

1246555

Q9I7Q8
GH14650p

1

1

High-throughput

0.407

High

1246556

CIC
Putative transcription factor capicua

1

1

High-throughput

0.407

High

1246557

Q9V3U6
26-29kD-proteinase

1

3

High-throughput

0.407

High

1246559

LZTR1
Leucine-zipper-like transcriptional regulator 1 homolog

1

1

High-throughput

0.407

High

1246562

TPP2
Tripeptidyl-peptidase 2

1

1

High-throughput

0.407

High

1246563

VATD1
V-type proton ATPase subunit D 1

1

1

High-throughput

0.407

High

1246565

Q9VAS8
Sponge, isoform E

1

2

High-throughput

0.407

High

1246566

Q9VAW1
peptidylprolyl isomerase

1

1

High-throughput

0.407

High

1246567

LARP
La-related protein 1

1

3

High-throughput

0.407

High

1246570

PUF
Ubiquitin carboxyl-terminal hydrolase puf

1

3

High-throughput

0.407

High

1246574

ATD3A
ATPase family AAA domain-containing protein 3A homolog

1

2

High-throughput

0.407

High

1246576

Q9VFP0
RH07106p

1

3

High-throughput

0.407

High

1246577

Q9VH97
Dynein heavy chain 1, isoform E

1

2

High-throughput

0.407

High

1246578

Q9VHH2
non-specific serine/threonine protein kinase

1

2

High-throughput

0.407

High

1246582

Q9VIB3
Carboxylic ester hydrolase

1

1

High-throughput

0.407

High

1246583

Q9VIC3
carboxylesterase

1

1

High-throughput

0.407

High

1246584

Q9VIJ9
Guanine nucleotide-binding protein-like 1

1

2

High-throughput

0.407

High

1246586

Q9VIP4
LP17758p

1

1

High-throughput

0.407

High

1246588

Q9VJ14
RING-type E3 ubiquitin transferase

1

2

High-throughput

0.407

High

1246594

Q9VKB0
threonine--tRNA ligase

1

1

High-throughput

0.407

High

1246595

C2D1
Coiled-coil and C2 domain-containing protein 1-like

1

6

High-throughput

0.407

High

1246598

Q9VM93
LD33094p

1

3

High-throughput

0.407

High

1246599

Q9VPR5
Splicing factor 3B subunit 1

1

2

High-throughput

0.407

High

1246601

Q9VQL0
Uncharacterized protein, isoform B

1

1

High-throughput

0.407

High

1246606

Q9VU79
Guanylate cyclase

1

1

High-throughput

0.407

High

1246607

Q9VU88
AT31531p

1

3

High-throughput

0.407

High

1246609

Q9VUN7
DDB1- and CUL4-associated factor 13

1

1

High-throughput

0.407

High

1246612

Q9VVK7
Nucleobindin 1

1

2

High-throughput

0.407

High

1246613

Q9VVV0
Uncharacterized protein, isoform A

1

19

High-throughput

0.407

High

1246615

Q9VW24
Mitogen-activated protein kinase kinase kinase

1

12

High-throughput

0.407

High

1246619

Q9VYP5
Uncharacterized protein, isoform B

1

5

High-throughput

0.407

High

1246628

Q9W2H2
Crossveinless 2

1

7

High-throughput

0.407

High

1246630

ZDHC8
Palmitoyltransferase ZDHHC8

1

2

High-throughput

0.407

High

1246632

Q9W3H8
Protein PALS1

1

12

High-throughput

0.407

High

1246633

Q9W425
Rabconnectin-3A

1

2

High-throughput

0.407

High

1246634

Q9W457
Serine hydroxymethyltransferase

1

1

High-throughput

0.407

High

1246640

PSA6
Proteasome subunit alpha type-6

1

1

High-throughput

0.407

High

607486

RS17
Small ribosomal subunit protein eS17

1

0

High-throughput

0.253

Low

874386

RS25
Small ribosomal subunit protein eS25

1

0

High-throughput

0.253

Low

1246552

Q95TP9
40S ribosomal protein S6

1

0

High-throughput

0.253

Low

1246627

Q9W1B9
Large ribosomal subunit protein uL11

1

0

High-throughput

0.253

Low

1246631

PIP82
Protein PIP82

1

0

High-throughput

0.253

Low

54485

A1Z8N0
Uncharacterized protein

1

0

High-throughput

0.232

Low

56686

A1ZAE2
BTB domain-containing protein

1

0

High-throughput

0.232

Low

56732

A1ZAH8
40S ribosomal protein S15

1

0

High-throughput

0.232

Low

231982

O44226
Elongin-B

1

0

High-throughput

0.232

Low

263466

GPRS
Serine-enriched protein

1

0

High-throughput

0.232

Low

304461

VILYA
RING finger protein vilya

1

0

High-throughput

0.232

Low

471480

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.232

Low

476939

NDKA
Nucleoside diphosphate kinase

1

0

High-throughput

0.232

Low

477674

SUHW
Zinc finger protein su(Hw)

1

0

High-throughput

0.232

Low

809481

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.232

Low

870603

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.232

Low

875419

KARG
Arginine kinase 1

1

0

High-throughput

0.232

Low

930392

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.232

Low

1019586

TRXR1
Thioredoxin reductase 1, mitochondrial

1

0

High-throughput

0.232

Low

1038231

IF4A
Eukaryotic initiation factor 4A

1

0

High-throughput

0.232

Low

1050656

FTF1B
Nuclear hormone receptor FTZ-F1 beta

1

0

High-throughput

0.232

Low

1060660

DDX49
Probable ATP-dependent RNA helicase Dbp45A

1

0

High-throughput

0.232

Low

1069902

Q0E993
Valine--tRNA ligase

1

0

High-throughput

0.232

Low

1070972

Q0KI98
Tryptophan--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low

1071021

Q0KIB3
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.232

Low

1246533

RRP8
Ribosomal RNA-processing protein 8

1

0

High-throughput

0.232

Low

1246535

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.232

Low

1246538

Q7KN74
Tetratricopeptide repeat domain 7, isoform A

1

0

High-throughput

0.232

Low

1246543

Q8IMK8
Protein TsetseEP domain-containing protein

1

0

High-throughput

0.232

Low

1246544

Q8INK2
Fatty acid-binding protein, muscle

1

0

High-throughput

0.232

Low

1246546

Q8MRM6
GH15213p

1

0

High-throughput

0.232

Low

1246547

WAT
Fatty acyl-CoA reductase wat

1

0

High-throughput

0.232

Low

1246550

Q8T421
AT21561p

1

0

High-throughput

0.232

Low

1246558

Q9V3Z4
GH11341p

1

0

High-throughput

0.232

Low

1246560

Y9776
Zinc finger matrin-type protein CG9776

1

0

High-throughput

0.232

Low

1246561

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.232

Low

1246564

CIA30
Complex I intermediate-associated protein 30, mitochondrial

1

0

High-throughput

0.232

Low

1246568

Y5521
Probable Rho GTPase-activating protein CG5521

1

0

High-throughput

0.232

Low

1246569

Q9VC14
FI01033p

1

0

High-throughput

0.232

Low

1246571

Q9VC89
Uncharacterized protein, isoform D

1

0

High-throughput

0.232

Low

1246572

Q9VDT9
Fibroblast growth factor

1

0

High-throughput

0.232

Low

1246573

Q9VE54
Uncharacterized protein, isoform A

1

0

High-throughput

0.232

Low

1246575

Q9VFJ1
rRNA biogenesis protein RRP36

1

0

High-throughput

0.232

Low

1246579

Q9VHN7
transketolase

1

0

High-throughput

0.232

Low

1246580

ATG13
Autophagy-related protein 13 homolog

1

0

High-throughput

0.232

Low

1246581

Q9VI72
Spindle assembly abnormal 4

1

0

High-throughput

0.232

Low

1246585

Q9VIK0
Alpha-methylacyl-CoA racemase, isoform A

1

0

High-throughput

0.232

Low

1246587

PCNA2
Proliferating cell nuclear antigen 2

1

0

High-throughput

0.232

Low

1246589

Q9VJ19
Large ribosomal subunit protein eL30

1

0

High-throughput

0.232

Low

1246590

Q9VJB3
Uncharacterized protein

1

0

High-throughput

0.232

Low

1246591

Q9VJX3
B4, isoform A

1

0

High-throughput

0.232

Low

1246596

SOYB
Putative ATP-dependent RNA helicase SoYb

1

0

High-throughput

0.232

Low

1246597

Q9VLB9
Cytoplasmic dynein 2 light intermediate chain 1

1

0

High-throughput

0.232

Low

1246600

Q9VQ78
Tubulin-specific chaperone D

1

0

High-throughput

0.232

Low

1246602

Q9VRF2
Uncoordinated

1

0

High-throughput

0.232

Low

1246603

Q9VSF5
GH02649p

1

0

High-throughput

0.232

Low

1246605

Q9VTX1
FI19811p1

1

0

High-throughput

0.232

Low

1246608

Q9VUN5
FI08508p

1

0

High-throughput

0.232

Low

1246610

Q9VUR2
LD31322p

1

0

High-throughput

0.232

Low

1246611

Q9VVA7
Tumor suppressor protein 101

1

0

High-throughput

0.232

Low

1246614

Q9VVW7
Canopy b

1

0

High-throughput

0.232

Low

1246616

Q9VXQ6
LD18191p

1

0

High-throughput

0.232

Low

1246617

Q9VXV3
Shattered

1

0

High-throughput

0.232

Low

1246620

C28C1
Probable cytochrome P450 28c1

1

0

High-throughput

0.232

Low

1246621

Q9VZ00
FI19420p1

1

0

High-throughput

0.232

Low

1246622

Q9VZ03
AT06648p

1

0

High-throughput

0.232

Low

1246623

Q9VZX7
Autophagy-related protein 2

1

0

High-throughput

0.232

Low

1246625

Q9W0T7
Dis3 like 3'-5' exoribonuclease 2, isoform A

1

0

High-throughput

0.232

Low

1246635

Q9W499
Large ribosomal subunit protein uL29

1

0

High-throughput

0.232

Low

1246636

Q9W4J3
Uncharacterized protein

1

0

High-throughput

0.232

Low

1246638

Q9W5C1
RE02292p

1

0

High-throughput

0.232

Low

1246639

Q9XZ10
V-type proton ATPase subunit a

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025