Protein: TYW4
tRNA wybutosine-synthesizing protein 4 (tRNA yW-synthesizing protein 4) (EC 2.1.1.290) (EC 2.3.1.231) (Leucine carboxyl methyltransferase 2) (tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase)

Gene: TYW4, LCMT2
Organism: Homo sapiens
Interactions: 24
UniProt ID: O60294

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0006400 - tRNA modification
GO:0008175 - tRNA methyltransferase activity
GO:0030488 - tRNA methylation
GO:0031591 - wybutosine biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

230477

DNJC7
DnaJ homolog subfamily C member 7

3

1

High-throughput

0.667

High

230465

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

2

0

High-throughput

0.602

High

230473

RN123
E3 ubiquitin-protein ligase RNF123

2

0

High-throughput

0.602

High

211434

ACTN4
Alpha-actinin-4

1

0

High-throughput

0.549

High

230459

DNJA2
DnaJ homolog subfamily A member 2

1

1

High-throughput

0.536

High

230463

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.513

High

230468

SYUA
Alpha-synuclein

1

0

High-throughput

0.513

High

230470

ACTA
Actin, aortic smooth muscle

1

0

High-throughput

0.513

High

230474

TBA1A
Tubulin alpha-1A chain

1

0

High-throughput

0.513

High

230476

NUDC3
NudC domain-containing protein 3

1

0

High-throughput

0.513

High

230480

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.513

High

230479

DNJB4
DnaJ homolog subfamily B member 4

1

1

High-throughput

0.489

High

230475

CCNJL
Cyclin-J-like protein

1

1

High-throughput

0.479

High

230467

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

230472

FGL1
Fibrinogen-like protein 1

3

0

High-throughput

0.347

High

230466

TKT
Transketolase

2

0

High-throughput

0.328

High

230478

UBAC1
Ubiquitin-associated domain-containing protein 1

2

0

High-throughput

0.328

High

119698

AP4M1
AP-4 complex subunit mu-1

1

0

High-throughput

0.279

Low

230460

VP26A
Vacuolar protein sorting-associated protein 26A

1

0

High-throughput

0.279

Low

230461

ZBED1
E3 SUMO-protein ligase ZBED1

1

0

High-throughput

0.279

Low

230471

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.279

Low

230462

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

230464

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

230469

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024