Protein: KAT8
Histone acetyltransferase KAT8 (EC 2.3.1.48) (Lysine acetyltransferase 8) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (MYST-1) (Males-absent on the first protein homolog) (hMOF) (Protein acetyltransferase KAT8) (EC 2.3.1.-) (Protein propionyltransferase KAT8) (EC 2.3.1.-)

Gene: KAT8
Organism: Homo sapiens
Interactions: 81
UniProt ID: Q9H7Z6

Gene Ontology (top 5):
GO:0000123 - histone acetyltransferase complex
GO:0000776 - kinetochore
GO:0003682 - chromatin binding
GO:0003712 - transcription coregulator activity
GO:0003713 - transcription coactivator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1148057

MSL1
Male-specific lethal 1 homolog

8

3

Small-scale

0.973

High

1235313

MS3L1
MSL complex subunit 3

5

11

Small-scale

0.930

High

1188191

KANL1
KAT8 regulatory NSL complex subunit 1

5

3

Small-scale

0.918

High

1333244

KAT8
Histone acetyltransferase KAT8

2

12

Small-scale

0.834

High

1333247

MSL2
E3 ubiquitin-protein ligase MSL2

5

1

Small-scale

0.722

High

903522

WDR5
WD repeat-containing protein 5

4

5

Small-scale

0.702

High

1313842

PHF20
PHD finger protein 20

4

4

Small-scale

0.694

High

1333253

MO4L1
Mortality factor 4-like protein 1

1

11

Small-scale

0.691

High

387528

P53
Cellular tumor antigen p53

4

4

Small-scale

0.688

High

917932

H4
Histone H4

4

10

Small-scale

0.683

High

935245

H31
Histone H3.1

4

19

Small-scale

0.683

High

68315

P20L1
PHD finger protein 20-like protein 1

3

4

Small-scale

0.656

High

848294

HCFC1
Host cell factor 1

3

1

Small-scale

0.656

High

975327

KMT2A
Histone-lysine N-methyltransferase 2A

2

7

Small-scale

0.639

High

1289438

SIR1
NAD-dependent protein deacetylase sirtuin-1

2

5

Small-scale

0.634

High

1070777

RBBP5
Retinoblastoma-binding protein 5

2

6

Small-scale

0.621

High

1333250

KANL3
KAT8 regulatory NSL complex subunit 3

2

1

High-throughput

0.611

High

918694

H2B1C
Histone H2B type 1-C/E/F/G/I

2

20

High-throughput

0.584

High

1230538

CCAR2
Cell cycle and apoptosis regulator protein 2

2

2

Small-scale

0.584

High

1290759

MCRS1
Microspherule protein 1

2

3

Small-scale

0.584

High

1333256

BAZ1B
Tyrosine-protein kinase BAZ1B

1

11

Small-scale

0.578

High

1031612

ATM
Serine-protein kinase ATM

1

10

Small-scale

0.573

High

370453

ESR1
Estrogen receptor

2

12

High-throughput

0.571

High

1333255

BAZ2A
Bromodomain adjacent to zinc finger domain protein 2A

1

11

Small-scale

0.561

High

1304108

RING2
E3 ubiquitin-protein ligase RING2

1

9

Small-scale

0.554

High

1019129

TP53B
TP53-binding protein 1

1

0

Small-scale

0.537

High

71242

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

4

High-throughput

0.536

High

555648

H2AX
Histone H2AX

1

11

Small-scale

0.536

High

1069512

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.536

High

1087406

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.536

High

1296016

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

1

1

High-throughput

0.536

High

1296250

Z512B
Zinc finger protein 512B

1

2

High-throughput

0.536

High

1333263

DYR1B
Dual specificity tyrosine-phosphorylation-regulated kinase 1B

1

4

High-throughput

0.536

High

391906

H2A1B
Histone H2A type 1-B/E

1

11

Small-scale

0.501

High

1304373

H4G
Histone H4-like protein type G

1

10

Small-scale

0.501

High

1318366

FOXP3
Forkhead box protein P3

1

6

Small-scale

0.501

High

1333257

PNMA2
Paraneoplastic antigen Ma2

1

2

High-throughput

0.489

High

1237155

PAF1
RNA polymerase II-associated factor 1 homolog

1

0

Small-scale

0.480

High

165718

SET1A
Histone-lysine N-methyltransferase SETD1A

1

6

High-throughput

0.479

High

175210

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

3

Small-scale

0.479

High

183161

KDM6A
Lysine-specific demethylase 6A

1

3

High-throughput

0.479

High

244948

BRD4
Bromodomain-containing protein 4

1

13

High-throughput

0.479

High

347907

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

518929

TPR
Nucleoprotein TPR

1

5

Small-scale

0.479

High

524587

LYL1
Protein lyl-1

1

1

High-throughput

0.479

High

556976

CREB1
Cyclic AMP-responsive element-binding protein 1

1

1

High-throughput

0.479

High

632908

TYY1
Transcriptional repressor protein YY1

1

3

High-throughput

0.479

High

678864

HXA9
Homeobox protein Hox-A9

1

4

Small-scale

0.479

High

692186

ELF1
ETS-related transcription factor Elf-1

1

7

High-throughput

0.479

High

782657

HNF4A
Hepatocyte nuclear factor 4-alpha

1

8

High-throughput

0.479

High

861931

PLK1
Serine/threonine-protein kinase PLK1

1

4

High-throughput

0.479

High

869537

ATN1
Atrophin-1

1

7

High-throughput

0.479

High

910035

1433E
14-3-3 protein epsilon

1

3

Small-scale

0.479

High

927537

1433Z
14-3-3 protein zeta/delta

1

5

Small-scale

0.479

High

944433

PRKDC
DNA-dependent protein kinase catalytic subunit

1

11

Small-scale

0.479

High

952629

H33
Histone H3.3

1

19

High-throughput

0.479

High

992605

ACK1
Activated CDC42 kinase 1

1

2

Small-scale

0.479

High

1077602

ELF2
ETS-related transcription factor Elf-2

1

8

High-throughput

0.479

High

1121199

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

3

Small-scale

0.479

High

1244498

NUP43
Nucleoporin Nup43

1

7

High-throughput

0.479

High

1269629

ESR2
Estrogen receptor beta

1

11

High-throughput

0.479

High

1304895

ELF4
ETS-related transcription factor Elf-4

1

8

High-throughput

0.479

High

1333246

KANL2
KAT8 regulatory NSL complex subunit 2

1

1

High-throughput

0.479

High

1333249

CXXC1
CXXC-type zinc finger protein 1

1

7

High-throughput

0.479

High

1333252

RERE
Arginine-glutamic acid dipeptide repeats protein

1

6

High-throughput

0.479

High

1333254

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1333259

YETS2
YEATS domain-containing protein 2

1

9

High-throughput

0.479

High

1333260

KMT2B
Histone-lysine N-methyltransferase 2B

1

5

High-throughput

0.479

High

1333261

SET1B
Histone-lysine N-methyltransferase SETD1B

1

7

High-throughput

0.479

High

1333262

ASF1A
Histone chaperone ASF1A

1

2

Small-scale

0.479

High

1333264

HCFC2
Host cell factor 2

1

1

High-throughput

0.479

High

267701

TADA3
Transcriptional adapter 3

1

0

High-throughput

0.458

High

1223190

ZZZ3
ZZ-type zinc finger-containing protein 3

1

0

High-throughput

0.458

High

1333245

CSR2B
Cysteine-rich protein 2-binding protein

1

0

High-throughput

0.458

High

1333248

MBIP1
MAP3K12-binding inhibitory protein 1

1

0

High-throughput

0.458

High

1333258

ZN608
Zinc finger protein 608

1

0

High-throughput

0.458

High

473736

MS3L2
MSL complex subunit 3B

1

1

Small-scale

0.445

High

831693

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.408

High

341514

UROK
Urokinase-type plasminogen activator

1

0

Small-scale

0.261

Low

1333251

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024