Protein: PE2R3
Prostaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (PGE2-R) (Prostanoid EP3 receptor)

Gene: PE2R3, PTGER3
Organism: Homo sapiens
Interactions: 116
UniProt ID: P43115

Gene Ontology (top 5):
GO:0004957 - prostaglandin E receptor activity
GO:0005635 - nuclear envelope
GO:0005886 - plasma membrane
GO:0006954 - inflammatory response
GO:0007186 - G protein-coupled receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

646023

AVR2A
Activin receptor type-2A

3

4

High-throughput

0.861

High

738310

BMR1A
Bone morphogenetic protein receptor type-1A

3

4

High-throughput

0.861

High

793098

AVR2B
Activin receptor type-2B

3

4

High-throughput

0.861

High

793112

PKN3
Serine/threonine-protein kinase N3

3

5

High-throughput

0.770

High

793162

GHRL
Appetite-regulating hormone

1

2

Small-scale

0.724

High

178126

IPO8
Importin-8

3

14

High-throughput

0.667

High

312201

IPO7
Importin-7

3

14

High-throughput

0.667

High

383678

ERBB2
Receptor tyrosine-protein kinase erbB-2

3

8

High-throughput

0.667

High

586010

SL9A1
Sodium/hydrogen exchanger 1

3

3

High-throughput

0.667

High

619208

AT2B4
Plasma membrane calcium-transporting ATPase 4

3

20

High-throughput

0.667

High

729241

VGFR3
Vascular endothelial growth factor receptor 3

3

2

High-throughput

0.667

High

787356

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

3

9

High-throughput

0.667

High

793099

EI2BA
Translation initiation factor eIF2B subunit alpha

3

9

High-throughput

0.667

High

793100

DIP2A
Disco-interacting protein 2 homolog A

3

2

High-throughput

0.667

High

793117

AN13D
Ankyrin repeat domain-containing protein 13D

3

2

High-throughput

0.667

High

793132

MIGA1
Mitoguardin 1

3

1

High-throughput

0.667

High

793145

IPO9
Importin-9

3

15

High-throughput

0.667

High

793146

MYADM
Myeloid-associated differentiation marker

3

1

High-throughput

0.667

High

793147

PKP4
Plakophilin-4

3

5

High-throughput

0.667

High

793148

PKP2
Plakophilin-2

3

4

High-throughput

0.667

High

793149

GCP2
Gamma-tubulin complex component 2

3

8

High-throughput

0.667

High

793151

OSBL8
Oxysterol-binding protein-related protein 8

3

3

High-throughput

0.667

High

793157

PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

3

2

High-throughput

0.667

High

793161

S39A1
Zinc transporter ZIP1

3

8

High-throughput

0.667

High

793170

TNPO3
Transportin-3

3

10

High-throughput

0.667

High

793096

TMM94
Transmembrane protein 94

3

0

High-throughput

0.638

High

793106

PKHG4
Puratrophin-1

3

0

High-throughput

0.638

High

793113

RHDF2
Inactive rhomboid protein 2

3

0

High-throughput

0.638

High

793126

C2CD5
C2 domain-containing protein 5

3

0

High-throughput

0.638

High

793137

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

3

0

High-throughput

0.638

High

793153

PININ
Pinin

3

0

High-throughput

0.638

High

793169

DHRS7
Dehydrogenase/reductase SDR family member 7

3

0

High-throughput

0.638

High

283168

RGS20
Regulator of G-protein signaling 20

2

11

High-throughput

0.628

High

793128

CKLF4
CKLF-like MARVEL transmembrane domain-containing protein 4

2

5

High-throughput

0.611

High

793134

CIP2A
Protein CIP2A

2

2

High-throughput

0.611

High

129234

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

3

14

High-throughput

0.609

High

256734

CAND2
Cullin-associated NEDD8-dissociated protein 2

3

6

High-throughput

0.609

High

793084

EI2BB
Translation initiation factor eIF2B subunit beta

3

9

High-throughput

0.609

High

793086

MFAP3
Microfibril-associated glycoprotein 3

3

1

High-throughput

0.609

High

793097

EI2BE
Translation initiation factor eIF2B subunit epsilon

3

6

High-throughput

0.609

High

793110

TYW1B
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B

3

2

High-throughput

0.609

High

793114

TMED8
Protein TMED8

3

4

High-throughput

0.609

High

793121

PKHH3
Pleckstrin homology domain-containing family H member 3

3

1

High-throughput

0.609

High

793124

ZCH18
Zinc finger CCCH domain-containing protein 18

3

2

High-throughput

0.609

High

793131

ARL10
ADP-ribosylation factor-like protein 10

3

8

High-throughput

0.609

High

793152

XPO4
Exportin-4

3

9

High-throughput

0.609

High

793155

CWC22
Pre-mRNA-splicing factor CWC22 homolog

3

2

High-throughput

0.609

High

793158

EI2BG
Translation initiation factor eIF2B subunit gamma

3

5

High-throughput

0.609

High

793160

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

3

2

High-throughput

0.609

High

793165

EI2BD
Translation initiation factor eIF2B subunit delta

3

9

High-throughput

0.609

High

280958

KRT38
Keratin, type I cuticular Ha8

2

4

High-throughput

0.590

High

793119

NT2NA
Notch homolog 2 N-terminal-like protein A

2

3

High-throughput

0.573

High

793094

REL
Proto-oncogene c-Rel

1

1

High-throughput

0.573

High

793163

RGS17
Regulator of G-protein signaling 17

1

11

High-throughput

0.573

High

421307

HYEP
Epoxide hydrolase 1

2

2

High-throughput

0.558

High

793129

VPS8
Vacuolar protein sorting-associated protein 8 homolog

2

1

High-throughput

0.558

High

324757

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

1

High-throughput

0.553

High

208103

SPY2
Protein sprouty homolog 2

1

0

High-throughput

0.549

High

489920

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

5

High-throughput

0.536

High

551086

ITF2
Transcription factor 4

1

1

High-throughput

0.523

High

793089

KR107
Keratin-associated protein 10-7

1

4

High-throughput

0.523

High

793090

KR108
Keratin-associated protein 10-8

1

4

High-throughput

0.523

High

793091

KR109
Keratin-associated protein 10-9

1

4

High-throughput

0.523

High

793102

K1H1
Keratin, type I cuticular Ha1

1

4

High-throughput

0.523

High

793108

K1C40
Keratin, type I cytoskeletal 40

1

3

High-throughput

0.523

High

793116

ATL4
ADAMTS-like protein 4

1

1

High-throughput

0.523

High

793127

TRI42
Tripartite motif-containing protein 42

1

2

High-throughput

0.523

High

777163

PEX19
Peroxisomal biogenesis factor 19

1

0

High-throughput

0.513

High

793104

SP6
Transcription factor Sp6

1

1

High-throughput

0.489

High

793139

NGBR
Dehydrodolichyl diphosphate synthase complex subunit NUS1

1

1

High-throughput

0.489

High

119929

AP3B1
AP-3 complex subunit beta-1

1

4

High-throughput

0.479

High

159341

PLD2
Phospholipase D2

1

2

High-throughput

0.479

High

655258

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

6

High-throughput

0.479

High

793087

GEMI4
Gem-associated protein 4

1

1

High-throughput

0.479

High

793103

CP51A
Lanosterol 14-alpha demethylase

1

1

High-throughput

0.479

High

793118

DYM
Dymeclin

1

2

High-throughput

0.479

High

793142

CREL1
Protein disulfide isomerase CRELD1

1

3

High-throughput

0.479

High

793143

EXOC2
Exocyst complex component 2

1

4

High-throughput

0.479

High

793156

RAB18
Ras-related protein Rab-18

1

4

High-throughput

0.479

High

793166

IPO11
Importin-11

1

14

High-throughput

0.479

High

793093

EREP3
Protein ENTREP3

1

0

High-throughput

0.458

High

793111

RETST
All-trans-retinol 13,14-reductase

1

0

High-throughput

0.458

High

793115

LRIG3
Leucine-rich repeats and immunoglobulin-like domains protein 3

1

0

High-throughput

0.458

High

793123

KTN1
Kinectin

1

0

High-throughput

0.458

High

793125

LSR
Lipolysis-stimulated lipoprotein receptor

1

0

High-throughput

0.458

High

793136

LMBR1
Limb region 1 protein homolog

1

0

High-throughput

0.458

High

793159

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

793168

VANG2
Vang-like protein 2

1

0

High-throughput

0.458

High

793088

KR103
Keratin-associated protein 10-3

1

4

High-throughput

0.439

High

155546

TNPO2
Transportin-2

1

8

High-throughput

0.437

High

449218

LEG1
Galectin-1

1

2

High-throughput

0.437

High

793109

PHLB3
Pleckstrin homology-like domain family B member 3

1

1

High-throughput

0.437

High

793133

TBC15
TBC1 domain family member 15

1

1

High-throughput

0.437

High

793135

STAG1
Cohesin subunit SA-1

1

3

High-throughput

0.437

High

793150

FACD2
Fanconi anemia group D2 protein

1

2

High-throughput

0.437

High

793164

ARMX3
Armadillo repeat-containing X-linked protein 3

1

10

High-throughput

0.437

High

299246

FARP2
FERM, ARHGEF and pleckstrin domain-containing protein 2

3

0

High-throughput

0.347

High

567656

UBF1
Nucleolar transcription factor 1

3

0

High-throughput

0.347

High

793120

HEAT3
HEAT repeat-containing protein 3

3

0

High-throughput

0.347

High

793122

NOP9
Nucleolar protein 9

3

0

High-throughput

0.347

High

793138

EVI5L
EVI5-like protein

3

0

High-throughput

0.347

High

793140

HOOK2
Protein Hook homolog 2

3

0

High-throughput

0.347

High

793141

SAAL1
Protein SAAL1

3

0

High-throughput

0.347

High

793144

DOCK7
Dedicator of cytokinesis protein 7

3

0

High-throughput

0.347

High

793101

RNPS1
RNA-binding protein with serine-rich domain 1

2

0

High-throughput

0.318

High

327962

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

0

High-throughput

0.299

High

687129

CDD
Cytidine deaminase

1

0

High-throughput

0.299

High

793085

MEOX2
Homeobox protein MOX-2

1

0

High-throughput

0.299

High

793095

INCA1
Protein INCA1

1

0

High-throughput

0.299

High

793107

PR15B
Protein phosphatase 1 regulatory subunit 15B

2

0

High-throughput

0.288

High

793154

SMYD3
Histone-lysine N-methyltransferase SMYD3

1

0

High-throughput

0.279

Low

793167

MKLN1
Muskelin

1

0

Small-scale

0.275

Low

793105

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

793130

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.251

Low

327645

ECD
Protein ecdysoneless homolog

1

0

High-throughput

0.249

Low

793092

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024