Protein: MYSA
Myosin heavy chain, muscle

Gene: MYSA, Mhc
Organism: Drosophila melanogaster
Interactions: 107
UniProt ID: P05661

Gene Ontology (top 5):
GO:0000146 - microfilament motor activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005703 - polytene chromosome puff
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

432182

ACT6
Actin, indirect flight muscle

3

13

High-throughput

0.797

High

387015

ACT4
Actin, larval muscle

2

13

High-throughput

0.737

High

432160

MLC1
Myosin light chain alkali

2

17

High-throughput

0.737

High

432162

TPM2
Tropomyosin-2

2

7

High-throughput

0.737

High

432166

ACTN
Alpha-actinin, sarcomeric

2

10

High-throughput

0.737

High

432167

MLR
Myosin regulatory light chain 2

2

19

High-throughput

0.737

High

432172

MYSP2
Paramyosin, short form

2

18

High-throughput

0.737

High

432176

TNNC1
Troponin C, isoform 1

2

2

High-throughput

0.737

High

432197

Q7K569
Glycerol-3-phosphate dehydrogenase

2

2

High-throughput

0.659

High

432173

FTN
Flightin

4

0

Small-scale

0.654

High

432158

MYSA
Myosin heavy chain, muscle

1

17

Small-scale

0.647

High

432163

ACT5
Actin-87E

1

13

High-throughput

0.575

High

432177

TNNC2
Troponin C, isoform 2

1

2

High-throughput

0.575

High

432169

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

2

1

High-throughput

0.571

High

432180

KARG
Arginine kinase 1

2

1

High-throughput

0.571

High

432222

Q9VEB1
Malate dehydrogenase, mitochondrial

2

3

High-throughput

0.571

High

432231

Q9VSA9
CG7409

2

10

High-throughput

0.571

High

358447

ADH
Alcohol dehydrogenase

2

0

High-throughput

0.547

High

432164

GPDA
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

2

0

High-throughput

0.547

High

432168

TNNT
Troponin T, skeletal muscle

2

0

High-throughput

0.547

High

432174

TNNI
Troponin I

2

0

High-throughput

0.547

High

432175

GSTS1
Glutathione S-transferase S1

2

0

High-throughput

0.547

High

432199

Q8I062
GH23305p

2

0

High-throughput

0.547

High

432230

Q9VP84
IP06402p

2

0

High-throughput

0.547

High

432190

RAD51
DNA repair protein Rad51 homolog

1

1

High-throughput

0.541

High

432171

FAS2
Fasciclin-2

1

1

High-throughput

0.536

High

432221

Q9VBF5
Fructose-bisphosphate aldolase

2

2

High-throughput

0.533

High

432161

ALF
Fructose-bisphosphate aldolase

2

2

High-throughput

0.521

High

432226

Q9VHW4
FI21225p1

1

8

Small-scale

0.501

High

432194

Q7JW73
NAD kinase 2, mitochondrial

1

0

High-throughput

0.486

High

119503

M9NHC5
Uncharacterized protein, isoform C

1

10

High-throughput

0.479

High

232043

WBL
Protein windbeutel

1

2

High-throughput

0.479

High

432170

OSKA
Maternal effect protein oskar

1

1

Small-scale

0.479

High

432178

PP1B
Serine/threonine-protein phosphatase beta isoform

1

9

High-throughput

0.479

High

432185

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.479

High

432201

LASP1
LIM and SH3 domain protein Lasp

1

4

Small-scale

0.479

High

432219

FRIL
Ferritin light chain

1

1

High-throughput

0.479

High

432235

PYRG
CTP synthase

1

1

High-throughput

0.479

High

52992

A1Z7J1
Sticks and stones, isoform A

1

3

High-throughput

0.464

High

432215

OR49A
Odorant receptor 49a

1

1

High-throughput

0.464

High

432243

PTP61
Tyrosine-protein phosphatase non-receptor type 61F

1

0

Small-scale

0.458

High

432179

PRS4
26S proteasome regulatory subunit 4

1

1

High-throughput

0.457

High

432184

P91941
Adult cuticle protein 65Aa

1

7

High-throughput

0.457

High

56335

ZASP
PDZ and LIM domain protein Zasp

1

5

High-throughput

0.445

High

432165

MP20
Muscle-specific protein 20

1

2

High-throughput

0.445

High

432188

PCL
Polycomb protein Pcl

1

3

Small-scale

0.445

High

432208

Q8T0U6
Serine/threonine-protein phosphatase

1

8

High-throughput

0.445

High

432238

Q9VWG1
LD37169p

1

10

High-throughput

0.445

High

94192

D5SHN8
RT07823p

1

6

High-throughput

0.437

High

432246

Q9W3N0
FI21262p1

1

3

Small-scale

0.437

High

432159

TBA2
Tubulin alpha-2 chain

1

0

High-throughput

0.426

High

432181

DHE3
Glutamate dehydrogenase, mitochondrial

1

0

High-throughput

0.426

High

432202

MSRB
Methionine-R-sulfoxide reductase B1

1

0

High-throughput

0.426

High

432203

Q8IQB4
Z band alternatively spliced PDZ-motif protein 66, isoform E

1

0

High-throughput

0.426

High

432204

Q8IRD5
AT25231p

1

0

High-throughput

0.426

High

432224

Q9VH80
Telo2 interacting protein 1

1

0

High-throughput

0.426

High

54287

A1Z8H1
Cuticular protein 47Ea

1

5

High-throughput

0.407

High

68035

A8DRW0
Cuticular protein 49Aa

1

8

High-throughput

0.407

High

87078

Y5076
Uncharacterized protein CG45076

1

19

High-throughput

0.407

High

87142

FAU
Protein anoxia up-regulated

1

1

High-throughput

0.407

High

432187

ATPO
ATP synthase subunit O, mitochondrial

1

1

High-throughput

0.407

High

432191

Q5U126
GEO11286p1

1

5

High-throughput

0.407

High

432195

Q7K0W4
LD27203p

1

5

High-throughput

0.407

High

432196

Q7K2P1
Cuticular protein 50Cb

1

5

High-throughput

0.407

High

432200

Q8I0D4
RE20510p

1

1

High-throughput

0.407

High

432207

Q8SZM2
RH04334p

1

3

High-throughput

0.407

High

432211

Q95RB2
Cuticular protein 49Ae

1

7

High-throughput

0.407

High

432212

Q9I7Q5
Cuticular protein 65Au, isoform A

1

5

High-throughput

0.407

High

432218

Q9VA32
Cuticular protein 100A

1

5

High-throughput

0.407

High

432220

Q9VB86
LP07342p

1

1

High-throughput

0.407

High

432232

Q9VSN3
Cuticular protein 66D

1

6

High-throughput

0.407

High

432236

Q9VV46
Cuticular protein 72Ec

1

6

High-throughput

0.407

High

432240

Q9VZG2
Cuticular protein 64Aa

1

5

High-throughput

0.407

High

432241

Q9VZI4
Uncharacterized protein, isoform A

1

5

High-throughput

0.407

High

432242

Q9W077
Cuticular protein 62Bc, isoform A

1

5

High-throughput

0.407

High

432213

TITIN
Titin

1

12

High-throughput

0.381

High

432223

Q9VED1
IP07781p

2

0

High-throughput

0.305

High

432192

Q6IHY5
Cytochrome c oxidase subunit 7A-like 2, isoform A

2

0

High-throughput

0.298

High

432205

Q8MSI2
GH15296p

2

0

High-throughput

0.298

High

432206

Q8MT78
LD24677p

2

0

High-throughput

0.298

High

432227

Q9VIE8
Aconitate hydratase, mitochondrial

2

0

High-throughput

0.298

High

432228

Q9VM18
Trehalose 6-phosphate phosphatase

2

0

High-throughput

0.298

High

432244

ATPK
Putative ATP synthase subunit f, mitochondrial

2

0

High-throughput

0.298

High

432247

CISY
Probable citrate synthase, mitochondrial

2

0

High-throughput

0.298

High

57422

A1ZB58
MIP26102p

1

0

High-throughput

0.265

Low

432225

Q9VHG8
Uncharacterized protein

1

0

High-throughput

0.265

Low

68656

BL1S3
Biogenesis of lysosome-related organelles complex 1 subunit 3

1

0

High-throughput

0.249

Low

432189

CUA1
Adult cuticle protein 1

1

0

High-throughput

0.249

Low

432214

Q9U1K7
Thioredoxin domain-containing protein 17

1

0

High-throughput

0.249

Low

57243

ICLN
Methylosome subunit pICln

1

0

High-throughput

0.232

Low

305164

TRMB
tRNA

1

0

Small-scale

0.232

Low

432183

CYC2
Cytochrome c-2

1

0

High-throughput

0.232

Low

432186

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.232

Low

432193

Q7JUS9
Phosphate carrier protein, mitochondrial

1

0

High-throughput

0.232

Low

432198

QPCT2
Glutaminyl-peptide cyclotransferase

1

0

High-throughput

0.232

Low

432209

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

High-throughput

0.232

Low

432210

AT5F1
ATP synthase subunit b, mitochondrial

1

0

High-throughput

0.232

Low

432216

Q9V9U0
RE35358p

1

0

High-throughput

0.232

Low

432217

CP4C3
Cytochrome P450 4c3

1

0

High-throughput

0.232

Low

432229

HPF1
Histone PARylation factor 1-like

1

0

High-throughput

0.232

Low

432233

Q9VSY0
Cuticular protein 67B

1

0

High-throughput

0.232

Low

432234

NPLP2
Neuropeptide-like 2

1

0

High-throughput

0.232

Low

432237

Q9VVV1
RE59221p

1

0

High-throughput

0.232

Low

432239

SUN
Protein stunted

1

0

High-throughput

0.232

Low

432245

Q9W1F8
GEO08248p1

1

0

High-throughput

0.232

Low

432248

THEM6
Protein THEM6

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025