Protein: DDT4L
DNA damage-inducible transcript 4-like protein (HIF-1 responsive protein RTP801-like) (Protein regulated in development and DNA damage response 2) (REDD-2)

Gene: DDT4L, DDIT4L
Organism: Homo sapiens
Interactions: 214
UniProt ID: Q96D03

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0009968 - negative regulation of signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

912089

RUXG
Small nuclear ribonucleoprotein G

5

1

High-throughput

0.663

High

1287689

LSM7
U6 snRNA-associated Sm-like protein LSm7

4

2

High-throughput

0.637

High

212485

AAKB2
5'-AMP-activated protein kinase subunit beta-2

3

0

Small-scale

0.626

High

1063027

MO4L2
Mortality factor 4-like protein 2

3

1

High-throughput

0.616

High

272948

RFPL3
Ret finger protein-like 3

2

1

High-throughput

0.606

High

274278

STK16
Serine/threonine-protein kinase 16

2

1

High-throughput

0.606

High

474061

UBFL1
Upstream-binding factor 1-like protein 1

2

1

High-throughput

0.606

High

495586

THIO
Thioredoxin

2

1

High-throughput

0.606

High

681972

AKT1
RAC-alpha serine/threonine-protein kinase

2

1

High-throughput

0.606

High

757708

IF4A3
Eukaryotic initiation factor 4A-III

2

1

High-throughput

0.606

High

883381

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

2

1

High-throughput

0.606

High

924776

GRB2
Growth factor receptor-bound protein 2

2

2

High-throughput

0.606

High

1023090

STK4
Serine/threonine-protein kinase 4

2

1

High-throughput

0.606

High

1075069

MARE2
Microtubule-associated protein RP/EB family member 2

2

1

High-throughput

0.606

High

1218452

TEX14
Inactive serine/threonine-protein kinase TEX14

2

2

High-throughput

0.606

High

1243671

NAV1
Neuron navigator 1

2

2

High-throughput

0.606

High

1287651

DUS23
Dual specificity protein phosphatase 23

2

1

High-throughput

0.606

High

1287663

PARVG
Gamma-parvin

2

1

High-throughput

0.606

High

1287664

NEK6
Serine/threonine-protein kinase Nek6

2

3

High-throughput

0.606

High

1287671

EXOS5
Exosome complex component RRP46

2

1

High-throughput

0.606

High

1287682

HSPB7
Heat shock protein beta-7

2

1

High-throughput

0.606

High

1287691

MARE3
Microtubule-associated protein RP/EB family member 3

2

1

High-throughput

0.606

High

1287697

LSM5
U6 snRNA-associated Sm-like protein LSm5

2

3

High-throughput

0.606

High

1287698

NDK7
Nucleoside diphosphate kinase homolog 7

2

1

High-throughput

0.606

High

782279

NAA10
N-alpha-acetyltransferase 10

2

0

High-throughput

0.589

High

1287645

TSSK3
Testis-specific serine/threonine-protein kinase 3

2

0

High-throughput

0.589

High

120091

ST2B1
Sulfotransferase 2B1

2

0

High-throughput

0.580

High

131161

ZN593
Zinc finger protein 593

2

0

High-throughput

0.580

High

208224

DNPH1
5-hydroxymethyl-dUMP N-hydrolase

2

0

High-throughput

0.580

High

259963

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

2

0

High-throughput

0.580

High

309873

GA45G
Growth arrest and DNA damage-inducible protein GADD45 gamma

2

0

High-throughput

0.580

High

314115

BAG4
BAG family molecular chaperone regulator 4

2

0

High-throughput

0.580

High

325542

CLIC3
Chloride intracellular channel protein 3

2

0

High-throughput

0.580

High

596082

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

2

0

High-throughput

0.580

High

598267

FLNA
Filamin-A

2

0

High-throughput

0.580

High

637510

PSA1
Proteasome subunit alpha type-1

2

0

High-throughput

0.580

High

722478

RL22
Large ribosomal subunit protein eL22

2

0

High-throughput

0.580

High

825332

RPIA
Ribose-5-phosphate isomerase

2

0

High-throughput

0.580

High

834556

FHIT
Bis(5'-adenosyl)-triphosphatase

2

0

High-throughput

0.580

High

877498

CDN2D
Cyclin-dependent kinase 4 inhibitor D

2

0

High-throughput

0.580

High

884342

PCBP3
Poly(rC)-binding protein 3

2

0

High-throughput

0.580

High

901721

PFD3
Prefoldin subunit 3

2

0

High-throughput

0.580

High

976185

PTPS
6-pyruvoyl tetrahydrobiopterin synthase

2

0

High-throughput

0.580

High

1026641

FADD
FAS-associated death domain protein

2

0

High-throughput

0.580

High

1038223

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

2

0

High-throughput

0.580

High

1138850

OTU1
Ubiquitin thioesterase OTU1

2

0

High-throughput

0.580

High

1144466

KFA
Kynurenine formamidase

2

0

High-throughput

0.580

High

1144744

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

0

High-throughput

0.580

High

1148514

DUS29
Dual specificity phosphatase 29

2

0

High-throughput

0.580

High

1153138

TYW3
tRNA wybutosine-synthesizing protein 3 homolog

2

0

High-throughput

0.580

High

1192832

CATIP
Ciliogenesis-associated TTC17-interacting protein

2

0

High-throughput

0.580

High

1216617

CRLF3
Cytokine receptor-like factor 3

2

0

High-throughput

0.580

High

1231957

MT1M
Metallothionein-1M

2

0

High-throughput

0.580

High

1260175

HDAC7
Histone deacetylase 7

2

0

High-throughput

0.580

High

1263358

GEMI6
Gem-associated protein 6

2

0

High-throughput

0.580

High

1284948

EXOS8
Exosome complex component RRP43

2

0

High-throughput

0.580

High

1285549

AIDA
Axin interactor, dorsalization-associated protein

2

0

High-throughput

0.580

High

1287642

LRAT2
Protein LRATD2

2

0

High-throughput

0.580

High

1287656

TOLIP
Toll-interacting protein

2

0

High-throughput

0.580

High

1287658

SH3L3
SH3 domain-binding glutamic acid-rich-like protein 3

2

0

High-throughput

0.580

High

1287660

BAFL
Barrier-to-autointegration factor-like protein

2

0

High-throughput

0.580

High

1287667

CABP5
Calcium-binding protein 5

2

0

High-throughput

0.580

High

1287679

I36RA
Interleukin-36 receptor antagonist protein

2

0

High-throughput

0.580

High

1287680

CPNE7
Copine-7

2

0

High-throughput

0.580

High

1287685

MLX
Max-like protein X

2

0

High-throughput

0.580

High

1287695

EXOS1
Exosome complex component CSL4

2

0

High-throughput

0.580

High

277533

CCNK
Cyclin-K

2

1

High-throughput

0.553

High

735088

ZNF76
Zinc finger protein 76

2

1

High-throughput

0.553

High

833944

CLK2
Dual specificity protein kinase CLK2

2

1

High-throughput

0.553

High

834095

CLK3
Dual specificity protein kinase CLK3

2

1

High-throughput

0.553

High

912175

LSM3
U6 snRNA-associated Sm-like protein LSm3

2

2

High-throughput

0.553

High

1114414

LEGL
Galectin-related protein

2

2

High-throughput

0.553

High

1253497

PPL13
Placental protein 13-like

2

2

High-throughput

0.553

High

1264505

SEPT1
Septin-1

2

2

High-throughput

0.553

High

1287648

SEPT5
Septin-5

2

2

High-throughput

0.553

High

1287666

HM20A
High mobility group protein 20A

2

1

High-throughput

0.553

High

1287684

SEPT3
Neuronal-specific septin-3

2

2

High-throughput

0.553

High

1144599

TENS2
Tensin-2

2

0

High-throughput

0.551

High

1025500

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

0

High-throughput

0.549

High

471636

TFPT
TCF3 fusion partner

1

0

High-throughput

0.536

High

155851

SH21B
SH2 domain-containing protein 1B

1

4

High-throughput

0.515

High

243152

SH21A
SH2 domain-containing protein 1A

1

4

High-throughput

0.515

High

329121

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

1

High-throughput

0.515

High

782818

CSK
Tyrosine-protein kinase CSK

1

1

High-throughput

0.515

High

815013

LEG7
Galectin-7

1

2

High-throughput

0.515

High

1080617

ZIC1
Zinc finger protein ZIC 1

1

2

High-throughput

0.515

High

1200187

TRI74
Tripartite motif-containing protein 74

1

1

High-throughput

0.515

High

1255567

NEK7
Serine/threonine-protein kinase Nek7

1

3

High-throughput

0.515

High

1287638

NUD11
Diphosphoinositol polyphosphate phosphohydrolase 3-beta

1

1

High-throughput

0.515

High

1287693

PLAP
Phospholipase A-2-activating protein

1

1

High-throughput

0.515

High

210932

GET3
ATPase GET3

1

0

High-throughput

0.493

High

893441

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.493

High

927768

UBE2B
Ubiquitin-conjugating enzyme E2 B

1

0

High-throughput

0.493

High

942540

CTG1B
Cancer/testis antigen 1

1

0

High-throughput

0.493

High

985727

DEUP1
Deuterosome assembly protein 1

1

0

High-throughput

0.493

High

1015816

SCRN1
Secernin-1

1

0

High-throughput

0.493

High

1104138

EMAL3
Echinoderm microtubule-associated protein-like 3

1

0

High-throughput

0.493

High

1164644

PADI6
Protein-arginine deiminase type-6

1

0

High-throughput

0.493

High

1173529

TF2H5
General transcription factor IIH subunit 5

1

0

High-throughput

0.493

High

1203439

TRI69
E3 ubiquitin-protein ligase TRIM69

1

0

High-throughput

0.493

High

1256933

DOK4
Docking protein 4

1

0

High-throughput

0.493

High

1282747

GTPB3
tRNA modification GTPase GTPBP3, mitochondrial

1

0

High-throughput

0.493

High

1287643

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.493

High

1287647

PITX2
Pituitary homeobox 2

1

0

High-throughput

0.493

High

1287653

NIBA1
Protein Niban 1

1

0

High-throughput

0.493

High

1287657

CARD9
Caspase recruitment domain-containing protein 9

1

0

High-throughput

0.493

High

1287662

MYG1
MYG1 exonuclease

1

0

High-throughput

0.493

High

1287672

XPP1
Xaa-Pro aminopeptidase 1

1

0

High-throughput

0.493

High

1287678

WHRN
Whirlin

1

0

High-throughput

0.493

High

1287687

CTNA3
Catenin alpha-3

1

0

High-throughput

0.493

High

1287690

NDRG4
Protein NDRG4

1

0

High-throughput

0.493

High

1200199

TRI73
Tripartite motif-containing protein 73

1

1

High-throughput

0.481

High

851220

CCNH
Cyclin-H

1

1

High-throughput

0.470

High

1014183

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

1

High-throughput

0.470

High

1051899

IF4A2
Eukaryotic initiation factor 4A-II

1

1

High-throughput

0.470

High

1109977

Q3SXR9
VCX2 protein

1

1

High-throughput

0.470

High

1201507

ZN410
Zinc finger protein 410

1

1

High-throughput

0.470

High

1287644

STAC3
SH3 and cysteine-rich domain-containing protein 3

1

1

High-throughput

0.470

High

1287681

MO4L1
Mortality factor 4-like protein 1

1

1

High-throughput

0.470

High

1287659

VCX2
Variable charge X-linked protein 2

1

1

High-throughput

0.439

High

594609

PSB1
Proteasome subunit beta type-1

1

0

High-throughput

0.438

High

1190861

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

3

High-throughput

0.417

High

1287669

NXT2
NTF2-related export protein 2

2

0

High-throughput

0.320

High

1257235

LRC15
Leucine-rich repeat-containing protein 15

2

0

High-throughput

0.319

High

171321

EPHB6
Ephrin type-B receptor 6

2

0

High-throughput

0.316

High

263774

PR40A
Pre-mRNA-processing factor 40 homolog A

2

0

High-throughput

0.316

High

280684

KRT34
Keratin, type I cuticular Ha4

2

0

High-throughput

0.316

High

311434

ABCBB
Bile salt export pump

2

0

High-throughput

0.316

High

421409

ACBP
Acyl-CoA-binding protein

2

0

High-throughput

0.316

High

433440

YES
Tyrosine-protein kinase Yes

2

0

High-throughput

0.316

High

446737

SNRPA
U1 small nuclear ribonucleoprotein A

2

0

High-throughput

0.316

High

474665

NHLC4
NHL-repeat-containing protein 4

2

0

High-throughput

0.316

High

555244

NQO2
Ribosyldihydronicotinamide dehydrogenase [quinone]

2

0

High-throughput

0.316

High

555740

F261
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1

2

0

High-throughput

0.316

High

638558

RBTN1
Rhombotin-1

2

0

High-throughput

0.316

High

656130

PSB9
Proteasome subunit beta type-9

2

0

High-throughput

0.316

High

687140

CDD
Cytidine deaminase

2

0

High-throughput

0.316

High

777904

RFC5
Replication factor C subunit 5

2

0

High-throughput

0.316

High

793067

GUC1A
Guanylyl cyclase-activating protein 1

2

0

High-throughput

0.316

High

841057

AP4A
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]

2

0

High-throughput

0.316

High

863913

CRBB1
Beta-crystallin B1

2

0

High-throughput

0.316

High

879540

BID
BH3-interacting domain death agonist

2

0

High-throughput

0.316

High

880316

TCL1A
T-cell leukemia/lymphoma protein 1A

2

0

High-throughput

0.316

High

883457

M3KCL
MAP3K7 C-terminal-like protein

2

0

High-throughput

0.316

High

914879

YPEL5
Protein yippee-like 5

2

0

High-throughput

0.316

High

949655

TXN4A
Thioredoxin-like protein 4A

2

0

High-throughput

0.316

High

995888

PDE4C
3',5'-cyclic-AMP phosphodiesterase 4C

2

0

High-throughput

0.316

High

1023528

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

2

0

High-throughput

0.316

High

1044508

RAB32
Ras-related protein Rab-32

2

0

High-throughput

0.316

High

1050746

FHL2
Four and a half LIM domains protein 2

2

0

High-throughput

0.316

High

1066103

IF4H
Eukaryotic translation initiation factor 4H

2

0

High-throughput

0.316

High

1068414

PMVK
Phosphomevalonate kinase

2

0

High-throughput

0.316

High

1109821

ZSC23
Zinc finger and SCAN domain-containing protein 23

2

0

High-throughput

0.316

High

1115778

CE022
UPF0489 protein C5orf22

2

0

High-throughput

0.316

High

1154199

KRA56
Keratin-associated protein 5-6

2

0

High-throughput

0.316

High

1156922

CDPF1
Cysteine-rich DPF motif domain-containing protein 1

2

0

High-throughput

0.316

High

1157486

FAP20
Fanconi anemia core complex-associated protein 20

2

0

High-throughput

0.316

High

1183878

KCTD9
BTB/POZ domain-containing protein KCTD9

2

0

High-throughput

0.316

High

1184442

ZN765
Zinc finger protein 765

2

0

High-throughput

0.316

High

1191952

ARPIN
Arpin

2

0

High-throughput

0.316

High

1203158

PPR27
Protein phosphatase 1 regulatory subunit 27

2

0

High-throughput

0.316

High

1203352

NR2CA
Nuclear receptor 2C2-associated protein

2

0

High-throughput

0.316

High

1223521

P20D2
Xaa-Arg dipeptidase

2

0

High-throughput

0.316

High

1223901

F200C
Protein FAM200C

2

0

High-throughput

0.316

High

1229892

TTC5
Tetratricopeptide repeat protein 5

2

0

High-throughput

0.316

High

1232025

KDM8
Bifunctional peptidase and arginyl-hydroxylase JMJD5

2

0

High-throughput

0.316

High

1238628

SR1IP
Protein SREK1IP1

2

0

High-throughput

0.316

High

1262106

SEN15
tRNA-splicing endonuclease subunit Sen15

2

0

High-throughput

0.316

High

1262183

TEKT4
Tektin-4

2

0

High-throughput

0.316

High

1264335

MYLIP
E3 ubiquitin-protein ligase MYLIP

2

0

High-throughput

0.316

High

1272848

GPKOW
G-patch domain and KOW motifs-containing protein

2

0

High-throughput

0.316

High

1284922

ARK2N
Protein ARK2N

2

0

High-throughput

0.316

High

1286094

LENG1
Leukocyte receptor cluster member 1

2

0

High-throughput

0.316

High

1286629

COAC
Phosphopantothenoylcysteine decarboxylase

2

0

High-throughput

0.316

High

1287639

ACY3
N-acyl-aromatic-L-amino acid amidohydrolase

2

0

High-throughput

0.316

High

1287640

SC22A
Vesicle-trafficking protein SEC22a

2

0

High-throughput

0.316

High

1287649

NUD22
Uridine diphosphate glucose pyrophosphatase NUDT22

2

0

High-throughput

0.316

High

1287650

MIEN1
Migration and invasion enhancer 1

2

0

High-throughput

0.316

High

1287654

B2L14
Apoptosis facilitator Bcl-2-like protein 14

2

0

High-throughput

0.316

High

1287665

CHM1A
Charged multivesicular body protein 1a

2

0

High-throughput

0.316

High

1287668

NGB
Neuroglobin

2

0

High-throughput

0.316

High

1287670

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

2

0

High-throughput

0.316

High

1287674

PLS4
Phospholipid scramblase 4

2

0

High-throughput

0.316

High

1287675

TB22B
TBC1 domain family member 22B

2

0

High-throughput

0.316

High

1287676

T11L1
T-complex protein 11-like protein 1

2

0

High-throughput

0.316

High

1287677

CN119
Uncharacterized protein C14orf119

2

0

High-throughput

0.316

High

1287683

CS025
UPF0449 protein C19orf25

2

0

High-throughput

0.316

High

1287686

PUF60
Poly(U)-binding-splicing factor PUF60

2

0

High-throughput

0.316

High

1287688

SCOC
Short coiled-coil protein

2

0

High-throughput

0.316

High

1287694

MEMO1
Protein MEMO1

2

0

High-throughput

0.316

High

1287696

PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1

2

0

High-throughput

0.316

High

161231

VP26C
Vacuolar protein sorting-associated protein 26C

1

0

High-throughput

0.282

High

147131

ASTN1
Astrotactin-1

1

0

High-throughput

0.268

Low

180403

MAGB2
Melanoma-associated antigen B2

1

0

High-throughput

0.268

Low

264226

CDC45
Cell division control protein 45 homolog

1

0

High-throughput

0.268

Low

282710

RNF8
E3 ubiquitin-protein ligase RNF8

1

0

High-throughput

0.268

Low

423324

PDIA1
Protein disulfide-isomerase

1

0

High-throughput

0.268

Low

656413

PIT1
Pituitary-specific positive transcription factor 1

1

0

High-throughput

0.268

Low

849801

SUOX
Sulfite oxidase, mitochondrial

1

0

High-throughput

0.268

Low

878224

SEC13
Protein SEC13 homolog

1

0

High-throughput

0.268

Low

891580

MYL6
Myosin light polypeptide 6

1

0

High-throughput

0.268

Low

1048558

VEZF1
Vascular endothelial zinc finger 1

1

0

High-throughput

0.268

Low

1269011

SORL
Sortilin-related receptor

1

0

High-throughput

0.268

Low

1281547

MYDGF
Myeloid-derived growth factor

1

0

High-throughput

0.268

Low

1287641

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

1

0

High-throughput

0.268

Low

1287646

PRP18
Pre-mRNA-splicing factor 18

1

0

High-throughput

0.268

Low

1287652

SYTM
Threonine--tRNA ligase, mitochondrial

1

0

High-throughput

0.268

Low

1287655

NDEL1
Nuclear distribution protein nudE-like 1

1

0

High-throughput

0.268

Low

1287661

DCTP1
dCTP pyrophosphatase 1

1

0

High-throughput

0.268

Low

1287673

ARHG3
Rho guanine nucleotide exchange factor 3

1

0

High-throughput

0.268

Low

1287692

TCF19
Transcription factor 19

1

0

High-throughput

0.268

Low

1287699

EMIL1
EMILIN-1

1

0

High-throughput

0.268

Low

517399

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.238

Low

1153165

CENPP
Centromere protein P

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024