Protein: MGRN1
E3 ubiquitin-protein ligase MGRN1 (EC 2.3.2.27) (Mahogunin RING finger protein 1) (RING finger protein 156) (RING-type E3 ubiquitin transferase MGRN1)

Gene: MGRN1
Organism: Homo sapiens
Interactions: 83
UniProt ID: O60291

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005769 - early endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

230126

UB2D1
Ubiquitin-conjugating enzyme E2 D1

2

6

Small-scale

0.800

High

230166

TS101
Tumor susceptibility gene 101 protein

5

1

Small-scale

0.729

High

230127

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

6

High-throughput

0.698

High

230130

UB2G2
Ubiquitin-conjugating enzyme E2 G2

1

7

High-throughput

0.698

High

230131

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

6

High-throughput

0.698

High

230132

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

6

High-throughput

0.698

High

230133

UBC9
SUMO-conjugating enzyme UBC9

1

7

High-throughput

0.698

High

230162

UBE2W
Ubiquitin-conjugating enzyme E2 W

1

9

High-throughput

0.698

High

230172

UBE2T
Ubiquitin-conjugating enzyme E2 T

1

7

High-throughput

0.698

High

230183

UB2D4
Ubiquitin-conjugating enzyme E2 D4

1

6

High-throughput

0.698

High

230153

ANR46
Ankyrin repeat domain-containing protein 46

3

1

High-throughput

0.675

High

230148

BTNL8
Butyrophilin-like protein 8

3

1

High-throughput

0.667

High

230136

MSHR
Melanocyte-stimulating hormone receptor

3

2

Small-scale

0.640

High

230107

ATRN
Attractin

2

4

High-throughput

0.628

High

230151

MEGF8
Multiple epidermal growth factor-like domains protein 8

2

4

High-throughput

0.628

High

230182

PSG8
Pregnancy-specific beta-1-glycoprotein 8

2

2

High-throughput

0.628

High

230180

AMFR
E3 ubiquitin-protein ligase AMFR

2

2

Small-scale

0.624

High

230156

UB2J2
Ubiquitin-conjugating enzyme E2 J2

1

9

High-throughput

0.621

High

230140

PDCD2
Programmed cell death protein 2

2

0

High-throughput

0.602

High

230177

INT7
Integrator complex subunit 7

2

0

High-throughput

0.602

High

230139

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

2

0

High-throughput

0.585

High

230181

AT1B4
Protein ATP1B4

2

0

High-throughput

0.585

High

230158

UB2Q2
Ubiquitin-conjugating enzyme E2 Q2

1

0

High-throughput

0.560

High

230106

NMT2
Glycylpeptide N-tetradecanoyltransferase 2

1

1

High-throughput

0.536

High

230110

PPB1
Alkaline phosphatase, placental type

1

1

High-throughput

0.536

High

230112

PPBN
Alkaline phosphatase, germ cell type

1

1

High-throughput

0.536

High

230113

PSG1
Pregnancy-specific beta-1-glycoprotein 1

1

2

High-throughput

0.536

High

230119

NMT1
Glycylpeptide N-tetradecanoyltransferase 1

1

1

High-throughput

0.536

High

230141

PSG3
Pregnancy-specific beta-1-glycoprotein 3

1

2

High-throughput

0.536

High

230146

HSDL1
Inactive hydroxysteroid dehydrogenase-like protein 1

1

1

High-throughput

0.536

High

230178

BTNL2
Butyrophilin-like protein 2

1

1

High-throughput

0.536

High

230179

FBX2
F-box only protein 2

1

2

High-throughput

0.536

High

230152

TRI74
Tripartite motif-containing protein 74

1

0

High-throughput

0.518

High

135833

WNT7A
Protein Wnt-7a

1

0

High-throughput

0.513

High

230108

LY6H
Lymphocyte antigen 6H

1

0

High-throughput

0.513

High

230109

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

0

High-throughput

0.513

High

230111

LEG1
Galectin-1

1

0

High-throughput

0.513

High

230116

ASM
Sphingomyelin phosphodiesterase

1

0

High-throughput

0.513

High

230117

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

0

High-throughput

0.513

High

230118

CALX
Calnexin

1

0

High-throughput

0.513

High

230129

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.513

High

230138

PTC1
Protein patched homolog 1

1

0

High-throughput

0.513

High

230159

CANT1
Soluble calcium-activated nucleotidase 1

1

0

High-throughput

0.513

High

230161

T106A
Transmembrane protein 106A

1

0

High-throughput

0.513

High

230168

SIRPD
Signal-regulatory protein delta

1

0

High-throughput

0.513

High

230170

PGES2
Prostaglandin E synthase 2

1

0

High-throughput

0.513

High

230171

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.513

High

230185

AP1M2
AP-1 complex subunit mu-2

1

0

High-throughput

0.513

High

230174

TMPS4
Transmembrane protease serine 4

1

0

High-throughput

0.493

High

120766

APBB1
Amyloid beta precursor protein binding family B member 1

1

1

Small-scale

0.479

High

230120

ARRB2
Beta-arrestin-2

1

1

Small-scale

0.479

High

230121

MC4R
Melanocortin receptor 4

1

2

Small-scale

0.479

High

230124

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

1

Small-scale

0.479

High

230125

ARRB1
Beta-arrestin-1

1

1

Small-scale

0.479

High

230135

ACTHR
Adrenocorticotropic hormone receptor

1

2

Small-scale

0.479

High

230137

CUL3
Cullin-3

1

1

High-throughput

0.479

High

230154

MFN1
Mitofusin-1

1

1

Small-scale

0.479

High

230164

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

1

Small-scale

0.479

High

230173

FBX6
F-box only protein 6

1

2

High-throughput

0.479

High

204788

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

230122

HSP74
Heat shock 70 kDa protein 4

1

0

Small-scale

0.458

High

230123

HD
Huntingtin

1

0

Small-scale

0.458

High

230128

ATX3
Ataxin-3

1

0

Small-scale

0.458

High

230134

TBA4A
Tubulin alpha-4A chain

1

0

Small-scale

0.458

High

230143

DUS6
Dual specificity protein phosphatase 6

1

0

High-throughput

0.458

High

230144

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

230150

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

230157

MRAP
Melanocortin-2 receptor accessory protein

1

0

Small-scale

0.458

High

230169

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

230155

CI040
Uncharacterized protein C9orf40

2

0

High-throughput

0.328

High

230167

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

2

0

High-throughput

0.328

High

230142

TAZ
Tafazzin

2

0

High-throughput

0.318

High

230114

PSPC
Surfactant protein C

1

0

High-throughput

0.279

Low

230115

EDN3
Endothelin-3

1

0

High-throughput

0.279

Low

230147

GPAT2
Glycerol-3-phosphate acyltransferase 2, mitochondrial

1

0

High-throughput

0.279

Low

230149

IGFL3
Insulin growth factor-like family member 3

1

0

High-throughput

0.279

Low

230160

PATE1
Prostate and testis expressed protein 1

1

0

High-throughput

0.279

Low

230163

ESPB1
Epididymal sperm-binding protein 1

1

0

High-throughput

0.279

Low

230165

TAFA4
Chemokine-like protein TAFA-4

1

0

High-throughput

0.279

Low

230175

CBLN4
Cerebellin-4

1

0

High-throughput

0.279

Low

230176

UQCC1
Ubiquinol-cytochrome c reductase complex assembly factor 1

1

0

High-throughput

0.279

Low

230184

PRG3
Proteoglycan 3

1

0

High-throughput

0.279

Low

230145

DB109
Putative beta-defensin 109B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024