Protein: UBP13
Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.4.19.12) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13)

Gene: UBP13, USP13
Organism: Homo sapiens
Interactions: 101
UniProt ID: Q92995

Gene Ontology (top 5):
GO:0004197 - cysteine-type endopeptidase activity
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

476145

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

9

20

Small-scale

0.969

High

509698

UBL4A
Ubiquitin-like protein 4A

2

20

Small-scale

0.828

High

803679

BAG6
Large proline-rich protein BAG6

2

7

Small-scale

0.806

High

800610

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

2

16

Small-scale

0.776

High

834091

CLK3
Dual specificity protein kinase CLK3

1

6

Small-scale

0.747

High

890784

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

5

7

Small-scale

0.727

High

934369

CSK21
Casein kinase II subunit alpha

1

3

Small-scale

0.724

High

1057345

SMC1A
Structural maintenance of chromosomes protein 1A

5

4

Small-scale

0.716

High

1044016

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

8

High-throughput

0.698

High

992183

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

4

2

Small-scale

0.692

High

1273589

SMC3
Structural maintenance of chromosomes protein 3

4

2

Small-scale

0.691

High

224495

RAD21
Double-strand-break repair protein rad21 homolog

3

1

Small-scale

0.667

High

1079565

NEDD8
NEDD8

1

11

High-throughput

0.665

High

1240559

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

3

0

High-throughput

0.638

High

1273573

RPP25
Ribonuclease P protein subunit p25

3

0

High-throughput

0.638

High

1273580

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.631

High

1273567

TRI63
E3 ubiquitin-protein ligase TRIM63

2

20

Small-scale

0.629

High

1273576

TRI55
Tripartite motif-containing protein 55

2

20

Small-scale

0.629

High

160694

AURKA
Aurora kinase A

1

17

Small-scale

0.618

High

861876

PLK1
Serine/threonine-protein kinase PLK1

1

17

High-throughput

0.618

High

872196

RD23A
UV excision repair protein RAD23 homolog A

1

16

Small-scale

0.618

High

1146699

A16L1
Autophagy-related protein 16-1

1

8

High-throughput

0.618

High

1273584

UBQL2
Ubiquilin-2

1

6

High-throughput

0.618

High

1273587

FZR1
Fizzy-related protein homolog

1

9

Small-scale

0.618

High

868281

ATX3
Ataxin-3

2

2

High-throughput

0.611

High

1065149

DAZP2
DAZ-associated protein 2

2

1

High-throughput

0.606

High

969505

ODO1
2-oxoglutarate dehydrogenase complex component E1

2

1

Small-scale

0.601

High

1273572

UIMC1
BRCA1-A complex subunit RAP80

2

0

Small-scale

0.598

High

1100546

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

2

1

Small-scale

0.584

High

1232552

STAG2
Cohesin subunit SA-2

2

1

Small-scale

0.584

High

1076853

TWST1
Twist-related protein 1

1

3

Small-scale

0.578

High

1272223

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

2

0

Small-scale

0.576

High

1039137

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

1

High-throughput

0.575

High

199134

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

20

Small-scale

0.561

High

875190

TERA
Transitional endoplasmic reticulum ATPase

1

1

Small-scale

0.561

High

1056916

MDC1
Mediator of DNA damage checkpoint protein 1

1

5

Small-scale

0.561

High

1266873

TOPB1
DNA topoisomerase 2-binding protein 1

1

4

Small-scale

0.561

High

1273586

AMFR
E3 ubiquitin-protein ligase AMFR

1

6

Small-scale

0.561

High

1191062

WAPL
Wings apart-like protein homolog

2

0

Small-scale

0.559

High

1273577

ATG5
Autophagy protein 5

1

0

Small-scale

0.554

High

150738

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

5

High-throughput

0.541

High

1132431

FBP1L
Formin-binding protein 1-like

1

3

High-throughput

0.541

High

1273574

FUND2
FUN14 domain-containing protein 2

1

1

High-throughput

0.541

High

181883

SOCS1
Suppressor of cytokine signaling 1

1

4

High-throughput

0.536

High

235992

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

2

High-throughput

0.536

High

739787

SRP14
Signal recognition particle 14 kDa protein

1

1

High-throughput

0.536

High

1273582

DDX28
Probable ATP-dependent RNA helicase DDX28

1

8

High-throughput

0.536

High

347510

MYC
Myc proto-oncogene protein

1

12

Small-scale

0.515

High

1273569

FAF2
FAS-associated factor 2

1

1

High-throughput

0.515

High

1273570

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

17

High-throughput

0.515

High

1273578

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

6

High-throughput

0.515

High

1273579

CYBP
Calcyclin-binding protein

1

1

High-throughput

0.515

High

1025887

TADBP
TAR DNA-binding protein 43

1

7

High-throughput

0.515

High

304447

REC8
Meiotic recombination protein REC8 homolog

1

0

High-throughput

0.513

High

1273592

VATD
V-type proton ATPase subunit D

1

0

High-throughput

0.513

High

1273585

MYO15
Unconventional myosin-XV

1

5

High-throughput

0.494

High

739216

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.493

High

1251696

NPL4
Nuclear protein localization protein 4 homolog

1

0

High-throughput

0.493

High

1273581

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.493

High

1273568

EMID1
EMI domain-containing protein 1

1

2

High-throughput

0.489

High

1039508

LAPM5
Lysosomal-associated transmembrane protein 5

1

0

High-throughput

0.486

High

244748

BRD4
Bromodomain-containing protein 4

1

17

High-throughput

0.479

High

252929

MITF
Microphthalmia-associated transcription factor

1

2

Small-scale

0.479

High

326735

SNAI1
Zinc finger protein SNAI1

1

11

Small-scale

0.479

High

449785

HMGB1
High mobility group protein B1

1

4

Small-scale

0.479

High

553356

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.479

High

651871

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

714343

HSP74
Heat shock 70 kDa protein 4

1

8

Small-scale

0.479

High

717260

CTNB1
Catenin beta-1

1

9

Small-scale

0.479

High

721083

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.479

High

741077

ZEB1
Zinc finger E-box-binding homeobox 1

1

4

Small-scale

0.479

High

786404

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

8

Small-scale

0.479

High

823463

PAXI
Paxillin

1

1

Small-scale

0.479

High

826027

FAS
Fatty acid synthase

1

3

Small-scale

0.479

High

853017

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

5

Small-scale

0.479

High

862449

ACLY
ATP-citrate synthase

1

1

Small-scale

0.479

High

869832

PMS1
PMS1 protein homolog 1

1

1

High-throughput

0.479

High

941261

RNF4
E3 ubiquitin-protein ligase RNF4

1

6

High-throughput

0.479

High

1031245

SKP2
S-phase kinase-associated protein 2

1

4

Small-scale

0.479

High

1171098

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

1203557

STING
Stimulator of interferon genes protein

1

8

Small-scale

0.479

High

1261572

STAG1
Cohesin subunit SA-1

1

1

Small-scale

0.479

High

1262969

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

3

Small-scale

0.479

High

1264870

RFFL
E3 ubiquitin-protein ligase rififylin

1

11

Small-scale

0.479

High

1273571

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

4

Small-scale

0.479

High

1273593

ZHX2
Zinc fingers and homeoboxes protein 2

1

2

Small-scale

0.479

High

1273583

TRPC4
Short transient receptor potential channel 4

1

1

High-throughput

0.470

High

1273591

KCTD3
BTB/POZ domain-containing protein KCTD3

1

8

High-throughput

0.470

High

495584

THIO
Thioredoxin

1

0

Small-scale

0.458

High

671889

PDIA3
Protein disulfide-isomerase A3

1

0

High-throughput

0.458

High

1184845

GET4
Golgi to ER traffic protein 4 homolog

1

0

Small-scale

0.458

High

608921

SPR2D
Small proline-rich protein 2D

1

0

High-throughput

0.438

High

120167

TLR4
Toll-like receptor 4

1

1

Small-scale

0.437

High

672983

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

1

Small-scale

0.437

High

995999

DSC1
Desmocollin-1

1

1

Small-scale

0.437

High

1079766

EREP1
Endosomal transmembrane epsin interactor 1

1

1

Small-scale

0.417

High

1030401

G3BP1
Ras GTPase-activating protein-binding protein 1

1

3

Small-scale

0.408

High

1162098

RHDF2
Inactive rhomboid protein 2

1

0

Small-scale

0.292

High

1273575

RM20
Large ribosomal subunit protein bL20m

1

0

High-throughput

0.282

High

1273590

TCAF1
TRPM8 channel-associated factor 1

1

0

High-throughput

0.269

Low

1273588

LORF1
LINE-1 retrotransposable element ORF1 protein

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024