Protein: DSC2
Desmocollin-2 (Cadherin family member 2) (Desmocollin-3) (Desmosomal glycoprotein II) (Desmosomal glycoprotein III)

Gene: DSC2
Organism: Homo sapiens
Interactions: 154
UniProt ID: Q02487

Gene Ontology (top 5):
GO:0001533 - cornified envelope
GO:0005509 - calcium ion binding
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0005912 - adherens junction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

971010

DSG2
Desmoglein-2

2

18

Small-scale

0.768

High

532930

PRG2
Bone marrow proteoglycan

1

2

High-throughput

0.691

High

971044

CLC2B
C-type lectin domain family 2 member B

1

10

High-throughput

0.691

High

971062

SIRPD
Signal-regulatory protein delta

1

1

High-throughput

0.691

High

971076

BTNL2
Butyrophilin-like protein 2

1

7

High-throughput

0.691

High

971078

PSG11
Pregnancy-specific beta-1-glycoprotein 11

1

6

High-throughput

0.691

High

971019

CC50B
Cell cycle control protein 50B

2

3

High-throughput

0.628

High

971057

PKP2
Plakophilin-2

1

20

Small-scale

0.621

High

971080

PKP3
Plakophilin-3

1

20

Small-scale

0.621

High

971018

CEA21
Carcinoembryonic antigen-related cell adhesion molecule 21

1

6

High-throughput

0.618

High

542286

PLAK
Junction plakoglobin

1

20

Small-scale

0.618

High

940401

CXAR
Coxsackievirus and adenovirus receptor

1

7

High-throughput

0.618

High

970755

DSG1
Desmoglein-1

1

17

Small-scale

0.618

High

971051

GMCL1
Germ cell-less protein-like 1

3

3

High-throughput

0.609

High

348626

RASN
GTPase NRas

2

20

High-throughput

0.584

High

350090

RASK
GTPase KRas

2

19

High-throughput

0.584

High

506975

LAMP1
Lysosome-associated membrane glycoprotein 1

2

6

High-throughput

0.584

High

567018

CXA1
Gap junction alpha-1 protein

2

6

Small-scale

0.584

High

713786

RYK
Tyrosine-protein kinase RYK

2

20

Small-scale

0.584

High

914018

RB11A
Ras-related protein Rab-11A

2

7

High-throughput

0.584

High

915618

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

410557

CD1A
T-cell surface glycoprotein CD1a

1

7

High-throughput

0.536

High

565912

AATC
Aspartate aminotransferase, cytoplasmic

1

3

High-throughput

0.536

High

964640

IL5RA
Interleukin-5 receptor subunit alpha

1

20

High-throughput

0.536

High

971032

CERS3
Ceramide synthase 3

1

1

High-throughput

0.536

High

971035

NRSN1
Neurensin-1

1

2

High-throughput

0.536

High

971037

LIRA3
Leukocyte immunoglobulin-like receptor subfamily A member 3

1

3

High-throughput

0.536

High

971039

FNDC5
Fibronectin type III domain-containing protein 5

1

2

High-throughput

0.536

High

971043

ZDH19
Palmitoyltransferase ZDHHC19

1

7

High-throughput

0.536

High

971056

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

9

High-throughput

0.536

High

971059

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

12

High-throughput

0.536

High

971068

SDF2L
Stromal cell-derived factor 2-like protein 1

1

5

High-throughput

0.536

High

971077

FBX2
F-box only protein 2

1

3

High-throughput

0.536

High

244307

BRD4
Bromodomain-containing protein 4

2

3

High-throughput

0.533

High

631404

BRD2
Bromodomain-containing protein 2

2

6

High-throughput

0.533

High

277171

TNF13
Tumor necrosis factor ligand superfamily member 13

1

0

High-throughput

0.513

High

474709

CFC1
Cryptic protein

1

0

High-throughput

0.513

High

873693

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.513

High

971047

T106A
Transmembrane protein 106A

1

0

High-throughput

0.513

High

586693

CSK22
Casein kinase II subunit alpha'

1

4

High-throughput

0.489

High

621364

CMA1
Chymase

1

2

High-throughput

0.489

High

971021

GXLT1
Glucoside xylosyltransferase 1

1

1

High-throughput

0.489

High

971042

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

1

3

High-throughput

0.489

High

971049

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.489

High

971060

SRRT
Serrate RNA effector molecule homolog

1

1

High-throughput

0.489

High

971063

KLK15
Kallikrein-15

1

5

High-throughput

0.489

High

971070

MBNL1
Muscleblind-like protein 1

1

2

High-throughput

0.489

High

971079

SSUH2
Protein SSUH2 homolog

1

2

High-throughput

0.489

High

120397

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

146027

CLD4
Claudin-4

1

1

Small-scale

0.479

High

163790

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

9

High-throughput

0.479

High

178492

STX7
Syntaxin-7

1

6

High-throughput

0.479

High

212801

STX6
Syntaxin-6

1

2

High-throughput

0.479

High

279520

FLOT1
Flotillin-1

1

3

High-throughput

0.479

High

318110

DIRA3
GTP-binding protein Di-Ras3

1

11

High-throughput

0.479

High

338302

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.479

High

349259

RASH
GTPase HRas

1

19

High-throughput

0.479

High

384675

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.479

High

900393

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

901130

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

390186

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.479

High

390835

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

3

High-throughput

0.479

High

411680

LCK
Tyrosine-protein kinase Lck

1

13

High-throughput

0.479

High

433707

LYN
Tyrosine-protein kinase Lyn

1

14

High-throughput

0.479

High

436262

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

525909

IFM1
Interferon-induced transmembrane protein 1

1

4

High-throughput

0.479

High

527406

LAMP2
Lysosome-associated membrane glycoprotein 2

1

6

High-throughput

0.479

High

545331

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

551675

DESP
Desmoplakin

1

12

Small-scale

0.479

High

564486

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

592210

RAB5A
Ras-related protein Rab-5A

1

9

High-throughput

0.479

High

615698

GCSP
Glycine dehydrogenase

1

2

High-throughput

0.479

High

646814

1433T
14-3-3 protein theta

1

18

High-throughput

0.479

High

665215

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.479

High

666577

LTK
Leukocyte tyrosine kinase receptor

1

20

High-throughput

0.479

High

669993

MARCS
Myristoylated alanine-rich C-kinase substrate

1

6

High-throughput

0.479

High

683279

1433B
14-3-3 protein beta/alpha

1

18

High-throughput

0.479

High

683976

1433S
14-3-3 protein sigma

1

18

High-throughput

0.479

High

825390

LMAN1
Protein ERGIC-53

1

2

High-throughput

0.479

High

830735

ARL4D
ADP-ribosylation factor-like protein 4D

1

18

High-throughput

0.479

High

838778

EMD
Emerin

1

2

High-throughput

0.479

High

845445

RAB9A
Ras-related protein Rab-9A

1

14

High-throughput

0.479

High

852442

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

872427

EPHA5
Ephrin type-A receptor 5

1

20

High-throughput

0.479

High

872632

EPHA4
Ephrin type-A receptor 4

1

20

High-throughput

0.479

High

876362

AFAD
Afadin

1

10

High-throughput

0.479

High

881501

ARL4C
ADP-ribosylation factor-like protein 4C

1

15

High-throughput

0.479

High

884473

RAB25
Ras-related protein Rab-25

1

7

High-throughput

0.479

High

890106

SC61B
Protein transport protein Sec61 subunit beta

1

2

High-throughput

0.479

High

892326

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

893916

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

895046

RAB2A
Ras-related protein Rab-2A

1

10

High-throughput

0.479

High

904459

1433G
14-3-3 protein gamma

1

18

High-throughput

0.479

High

909460

1433E
14-3-3 protein epsilon

1

1

High-throughput

0.479

High

912862

ARF6
ADP-ribosylation factor 6

1

7

High-throughput

0.479

High

925210

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

926944

1433Z
14-3-3 protein zeta/delta

1

18

High-throughput

0.479

High

950934

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

971007

CAV1
Caveolin-1

1

5

High-throughput

0.479

High

971008

1433F
14-3-3 protein eta

1

18

High-throughput

0.479

High

971009

STX4
Syntaxin-4

1

6

High-throughput

0.479

High

971013

RAB35
Ras-related protein Rab-35

1

9

High-throughput

0.479

High

971014

EPHA7
Ephrin type-A receptor 7

1

20

High-throughput

0.479

High

971015

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

971016

NTRK2
BDNF/NT-3 growth factors receptor

1

20

High-throughput

0.479

High

971017

OCLN
Occludin

1

3

High-throughput

0.479

High

971022

Q4LE69
1-phosphatidylinositol 4-kinase

1

7

High-throughput

0.479

High

971023

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.479

High

971024

STYK1
Tyrosine-protein kinase STYK1

1

20

High-throughput

0.479

High

971027

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

971029

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

971030

TM11B
Transmembrane protease serine 11B

1

10

High-throughput

0.479

High

971036

CXD3
Gap junction delta-3 protein

1

6

High-throughput

0.479

High

971041

DHB11
Estradiol 17-beta-dehydrogenase 11

1

12

High-throughput

0.479

High

971045

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

971046

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.479

High

971048

LRC59
Leucine-rich repeat-containing protein 59

1

7

High-throughput

0.479

High

971052

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.479

High

971054

PANX1
Pannexin-1

1

1

High-throughput

0.479

High

971055

SEC62
Translocation protein SEC62

1

1

High-throughput

0.479

High

971058

DERL1
Derlin-1

1

3

High-throughput

0.479

High

971064

DNJC5
DnaJ homolog subfamily C member 5

1

2

High-throughput

0.479

High

971065

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

971066

TMT1A
Thiol S-methyltransferase TMT1A

1

2

High-throughput

0.479

High

971067

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

971071

TMPS4
Transmembrane protease serine 4

1

9

High-throughput

0.479

High

971074

ANFY1
Rabankyrin-5

1

2

High-throughput

0.479

High

833714

CLK1
Dual specificity protein kinase CLK1

1

4

High-throughput

0.457

High

787643

PI4KA
Phosphatidylinositol 4-kinase alpha

1

7

High-throughput

0.445

High

971061

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

4

High-throughput

0.445

High

132455

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

170342

TIF1A
Transcription intermediary factor 1-alpha

1

5

High-throughput

0.437

High

273772

NU155
Nuclear pore complex protein Nup155

1

1

High-throughput

0.437

High

305420

ZFPL1
Zinc finger protein-like 1

1

2

High-throughput

0.437

High

817944

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.437

High

971012

BRD3
Bromodomain-containing protein 3

1

5

High-throughput

0.437

High

971020

AR13B
ADP-ribosylation factor-like protein 13B

1

16

High-throughput

0.437

High

971025

BRWD3
Bromodomain and WD repeat-containing protein 3

1

5

High-throughput

0.437

High

971031

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

971033

DEN6A
Protein DENND6A

1

1

High-throughput

0.437

High

971069

E41LA
Band 4.1-like protein 4A

1

15

High-throughput

0.437

High

971072

OTULL
Inactive ubiquitin thioesterase OTULINL

1

2

High-throughput

0.437

High

971073

TM216
Transmembrane protein 216

1

1

High-throughput

0.437

High

971075

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.437

High

789262

CNDD3
Condensin-2 complex subunit D3

1

1

High-throughput

0.407

High

853862

NCBP2
Nuclear cap-binding protein subunit 2

1

3

High-throughput

0.407

High

971038

PI4P1
Putative inactive phosphatidylinositol 4-kinase alpha-like protein P1

1

6

High-throughput

0.407

High

971053

TAFA4
Chemokine-like protein TAFA-4

2

0

High-throughput

0.328

High

971011

EP3A
Epididymal secretory protein E3-alpha

1

0

High-throughput

0.279

Low

971026

LYZL1
Lysozyme-like protein 1

1

0

High-throughput

0.279

Low

971034

S35F2
Solute carrier family 35 member F2

1

0

High-throughput

0.279

Low

971050

SKA1
Spindle and kinetochore-associated protein 1

1

0

High-throughput

0.279

Low

971040

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.249

Low

971028

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024