Protein: LIPA1
Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)

Gene: LIPA1, PPFIA1
Organism: Homo sapiens
Interactions: 179
UniProt ID: Q13136

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005925 - focal adhesion
GO:0007160 - cell-matrix adhesion
GO:0007165 - signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1025279

PTPRS
Receptor-type tyrosine-protein phosphatase S

3

11

Small-scale

0.845

High

489956

PTPRF
Receptor-type tyrosine-protein phosphatase F

4

11

Small-scale

0.803

High

616970

PTPRD
Receptor-type tyrosine-protein phosphatase delta

2

11

Small-scale

0.786

High

989669

CDK18
Cyclin-dependent kinase 18

2

13

High-throughput

0.783

High

1025277

LIPA1
Liprin-alpha-1

2

17

Small-scale

0.778

High

384757

NTRK1
High affinity nerve growth factor receptor

2

14

High-throughput

0.754

High

1025339

GRIP2
Glutamate receptor-interacting protein 2

2

14

Small-scale

0.754

High

930827

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

6

14

High-throughput

0.742

High

672101

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

6

4

High-throughput

0.740

High

915178

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

6

14

High-throughput

0.738

High

246438

DTNB
Dystrobrevin beta

4

4

High-throughput

0.705

High

1025295

MK06
Mitogen-activated protein kinase 6

1

11

High-throughput

0.691

High

683314

1433B
14-3-3 protein beta/alpha

4

20

High-throughput

0.691

High

904511

1433G
14-3-3 protein gamma

4

20

High-throughput

0.691

High

1025287

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

3

4

High-throughput

0.687

High

1025362

GIT1
ARF GTPase-activating protein GIT1

3

9

Small-scale

0.684

High

770582

TXLNA
Alpha-taxilin

3

16

High-throughput

0.676

High

1025278

GPS2
G protein pathway suppressor 2

3

1

High-throughput

0.667

High

1025350

PICK1
PRKCA-binding protein

1

0

High-throughput

0.656

High

646857

1433T
14-3-3 protein theta

3

20

High-throughput

0.650

High

981972

1433F
14-3-3 protein eta

3

20

High-throughput

0.650

High

259642

LIPA2
Liprin-alpha-2

1

16

Small-scale

0.647

High

719469

MERL
Merlin

2

11

High-throughput

0.628

High

1025304

L2GL2
LLGL scribble cell polarity complex component 2

2

3

High-throughput

0.628

High

255242

LIPA3
Liprin-alpha-3

1

15

Small-scale

0.621

High

1025311

LIPB1
Liprin-beta-1

1

17

Small-scale

0.621

High

1025318

LIPB2
Liprin-beta-2

1

18

Small-scale

0.621

High

374151

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

9

High-throughput

0.618

High

411701

LCK
Tyrosine-protein kinase Lck

1

10

High-throughput

0.618

High

433738

LYN
Tyrosine-protein kinase Lyn

1

10

High-throughput

0.618

High

507974

FGFR1
Fibroblast growth factor receptor 1

1

12

High-throughput

0.618

High

666590

LTK
Leukocyte tyrosine kinase receptor

1

12

High-throughput

0.618

High

835352

GSK3A
Glycogen synthase kinase-3 alpha

1

16

High-throughput

0.618

High

835712

GSK3B
Glycogen synthase kinase-3 beta

1

18

High-throughput

0.618

High

1025284

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

15

High-throughput

0.618

High

1025293

NTRK2
BDNF/NT-3 growth factors receptor

1

14

High-throughput

0.618

High

1025322

LNX1
E3 ubiquitin-protein ligase LNX

1

15

Small-scale

0.618

High

1025333

AURKB
Aurora kinase B

1

16

High-throughput

0.618

High

1025351

LATS2
Serine/threonine-protein kinase LATS2

1

20

High-throughput

0.618

High

851202

CCNH
Cyclin-H

3

1

High-throughput

0.617

High

1025353

MBIP1
MAP3K12-binding inhibitory protein 1

2

0

High-throughput

0.613

High

1025280

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

2

2

High-throughput

0.606

High

1025288

2A5A
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

2

4

High-throughput

0.606

High

397028

PAI2
Plasminogen activator inhibitor 2

2

0

High-throughput

0.602

High

1025312

EXOC8
Exocyst complex component 8

2

0

High-throughput

0.602

High

926994

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.601

High

1025342

DNJC5
DnaJ homolog subfamily C member 5

2

5

High-throughput

0.595

High

227331

PRKN
E3 ubiquitin-protein ligase parkin

2

7

High-throughput

0.584

High

348641

RASN
GTPase NRas

2

19

High-throughput

0.584

High

350130

RASK
GTPase KRas

2

19

High-throughput

0.584

High

912880

ARF6
ADP-ribosylation factor 6

2

3

High-throughput

0.584

High

915645

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

330075

DRC4
Dynein regulatory complex subunit 4

2

0

High-throughput

0.580

High

1025360

ING4
Inhibitor of growth protein 4

2

0

Small-scale

0.576

High

1025301

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.575

High

1025310

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

11

High-throughput

0.575

High

269412

STX11
Syntaxin-11

2

4

High-throughput

0.574

High

1025317

TTC9B
Tetratricopeptide repeat protein 9B

2

4

High-throughput

0.574

High

166833

ERC2
ERC protein 2

1

16

Small-scale

0.573

High

369516

ESR1
Estrogen receptor

2

15

High-throughput

0.571

High

1025285

ELOA1
Elongin-A

2

2

High-throughput

0.553

High

607953

FGFR4
Fibroblast growth factor receptor 4

1

12

High-throughput

0.553

High

749439

BRCA1
Breast cancer type 1 susceptibility protein

1

7

High-throughput

0.552

High

1025337

NECD
Necdin

1

6

High-throughput

0.541

High

1025321

CEP70
Centrosomal protein of 70 kDa

1

0

High-throughput

0.536

High

280875

KRT37
Keratin, type I cuticular Ha7

1

10

High-throughput

0.536

High

813425

CAPZB
F-actin-capping protein subunit beta

1

5

High-throughput

0.536

High

890956

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

14

High-throughput

0.536

High

909508

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.536

High

1025283

CUL2
Cullin-2

1

9

High-throughput

0.536

High

1025297

KIF7
Kinesin-like protein KIF7

1

4

High-throughput

0.536

High

1025307

TPGS1
Tubulin polyglutamylase complex subunit 1

1

1

High-throughput

0.536

High

1025324

BRK1
Protein BRICK1

1

2

High-throughput

0.536

High

1025336

CDC5L
Cell division cycle 5-like protein

1

2

High-throughput

0.536

High

1025348

E41L5
Band 4.1-like protein 5

1

9

High-throughput

0.536

High

533594

TNNT1
Troponin T, slow skeletal muscle

1

0

High-throughput

0.518

High

891737

ACTB
Actin, cytoplasmic 1

1

15

High-throughput

0.515

High

614022

TBG1
Tubulin gamma-1 chain

1

0

High-throughput

0.513

High

1025292

CART

1

0

High-throughput

0.513

High

1025320

I17RE
Interleukin-17 receptor E

1

0

High-throughput

0.513

High

1025347

GBA2
Non-lysosomal glucosylceramidase

1

0

High-throughput

0.513

High

1025363

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.513

High

1025361

CBPC1
Cytosolic carboxypeptidase 1

1

1

High-throughput

0.508

High

1025328

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

8

High-throughput

0.501

High

796067

MAGA9
Melanoma-associated antigen 9

1

6

High-throughput

0.489

High

1025305

BTNL9
Butyrophilin-like protein 9

1

6

High-throughput

0.489

High

120415

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

212820

STX6
Syntaxin-6

1

1

High-throughput

0.479

High

232138

KDM1A
Lysine-specific histone demethylase 1A

1

1

High-throughput

0.479

High

279537

FLOT1
Flotillin-1

1

4

High-throughput

0.479

High

322554

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

4

High-throughput

0.479

High

349284

RASH
GTPase HRas

1

14

High-throughput

0.479

High

408792

K1C18
Keratin, type I cytoskeletal 18

1

4

High-throughput

0.479

High

436281

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

506997

LAMP1
Lysosome-associated membrane glycoprotein 1

1

6

High-throughput

0.479

High

545349

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

564504

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

567038

CXA1
Gap junction alpha-1 protein

1

6

High-throughput

0.479

High

655349

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

11

High-throughput

0.479

High

670008

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

684010

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

726787

FUS
RNA-binding protein FUS

1

1

High-throughput

0.479

High

758214

CDN1A
Cyclin-dependent kinase inhibitor 1

1

1

High-throughput

0.479

High

793296

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.479

High

807342

RS10
Small ribosomal subunit protein eS10

1

3

High-throughput

0.479

High

845461

RAB9A
Ras-related protein Rab-9A

1

6

High-throughput

0.479

High

852457

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

881504

ARL4C
ADP-ribosylation factor-like protein 4C

1

9

High-throughput

0.479

High

882274

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

14

High-throughput

0.479

High

892344

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

893955

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

895059

RAB2A
Ras-related protein Rab-2A

1

4

High-throughput

0.479

High

900430

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

901144

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

914042

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.479

High

925243

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

940412

CXAR
Coxsackievirus and adenovirus receptor

1

2

High-throughput

0.479

High

950961

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

974793

CAV1
Caveolin-1

1

2

High-throughput

0.479

High

1025282

HDAC1
Histone deacetylase 1

1

13

High-throughput

0.479

High

1025289

RAB35
Ras-related protein Rab-35

1

3

High-throughput

0.479

High

1025290

NCOA2
Nuclear receptor coactivator 2

1

9

Small-scale

0.479

High

1025291

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

1025294

OCLN
Occludin

1

1

High-throughput

0.479

High

1025299

AR13B
ADP-ribosylation factor-like protein 13B

1

8

High-throughput

0.479

High

1025300

AMOT
Angiomotin

1

19

High-throughput

0.479

High

1025302

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.479

High

1025306

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

1025308

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1025325

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

1025326

ESR2
Estrogen receptor beta

1

15

High-throughput

0.479

High

1025340

TOLIP
Toll-interacting protein

1

2

High-throughput

0.479

High

1025341

VP33B
Vacuolar protein sorting-associated protein 33B

1

3

High-throughput

0.479

High

1025344

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1025346

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

1025349

E41LA
Band 4.1-like protein 4A

1

9

High-throughput

0.479

High

1025352

RNC
Ribonuclease 3

1

1

High-throughput

0.479

High

1025355

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1025357

BRPF3
Bromodomain and PHD finger-containing protein 3

1

3

High-throughput

0.479

High

1025358

FZR1
Fizzy-related protein homolog

1

6

High-throughput

0.479

High

1025359

CC14A
Dual specificity protein phosphatase CDC14A

1

4

High-throughput

0.479

High

959386

VIGLN
Vigilin

1

0

High-throughput

0.458

High

1025281

MTM1
Myotubularin

1

0

High-throughput

0.458

High

1025286

CAPR1
Caprin-1

1

0

High-throughput

0.458

High

1025319

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1025345

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1025329

CNKR1
Connector enhancer of kinase suppressor of ras 1

1

20

Small-scale

0.457

High

1025314

CNTRB
Centrobin

1

15

High-throughput

0.445

High

132468

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

178514

STX7
Syntaxin-7

1

3

High-throughput

0.437

High

244373

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.437

High

262445

TULP3
Tubby-related protein 3

1

4

High-throughput

0.437

High

305437

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

318123

DIRA3
GTP-binding protein Di-Ras3

1

3

High-throughput

0.437

High

379352

MYCN
N-myc proto-oncogene protein

1

6

High-throughput

0.437

High

552617

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

651091

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

720356

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

1025303

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.437

High

1025315

CXD3
Gap junction delta-3 protein

1

6

High-throughput

0.437

High

1025316

ARL14
ADP-ribosylation factor-like protein 14

1

5

High-throughput

0.437

High

1025327

TF3B
Transcription factor IIIB 90 kDa subunit

1

1

Small-scale

0.437

High

1025330

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

1025331

VP33A
Vacuolar protein sorting-associated protein 33A

1

3

High-throughput

0.437

High

1025332

PF21A
PHD finger protein 21A

1

7

High-throughput

0.437

High

1025335

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.437

High

1025343

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.437

High

1025356

RCOR1
REST corepressor 1

1

2

High-throughput

0.437

High

1025354

CTNL1
Alpha-catulin

1

0

Small-scale

0.426

High

626683

ADA1D
Alpha-1D adrenergic receptor

1

2

Small-scale

0.407

High

1025296

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

1

High-throughput

0.407

High

1025338

PHAF1
Phagosome assembly factor 1

3

0

High-throughput

0.347

High

1025313

CP4X1
Cytochrome P450 4X1

3

0

High-throughput

0.342

High

1025298

F161A
Protein FAM161A

2

0

High-throughput

0.337

High

579696

XRCC1
DNA repair protein XRCC1

1

0

High-throughput

0.279

Low

1025334

CC120
Coiled-coil domain-containing protein 120

1

0

High-throughput

0.279

Low

1025323

CAGE1
Cancer-associated gene 1 protein

1

0

High-throughput

0.251

Low

1025309

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024