Protein: BMPR2
Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)

Gene: BMPR2
Organism: Homo sapiens
Interactions: 87
UniProt ID: Q13873

Gene Ontology (top 5):
GO:0001568 - blood vessel development
GO:0001649 - osteoblast differentiation
GO:0001707 - mesoderm formation
GO:0001893 - maternal placenta development
GO:0001935 - endothelial cell proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

520078

BMP2
Bone morphogenetic protein 2

7

20

Small-scale

0.960

High

520153

BMP4
Bone morphogenetic protein 4

4

20

Small-scale

0.890

High

981119

ACVR1
Activin receptor type-1

3

20

Small-scale

0.868

High

574204

BMP7
Bone morphogenetic protein 7

3

20

Small-scale

0.848

High

792921

GDF5
Growth/differentiation factor 5

3

20

Small-scale

0.840

High

964104

CD83
CD83 antigen

2

2

High-throughput

0.811

High

1046389

GDF2
Growth/differentiation factor 2

2

20

Small-scale

0.778

High

738342

BMR1A
Bone morphogenetic protein receptor type-1A

2

20

Small-scale

0.776

High

122290

BMR1B
Bone morphogenetic protein receptor type-1B

2

20

Small-scale

0.754

High

738543

TGFR1
TGF-beta receptor type-1

2

20

Small-scale

0.754

High

522971

SRC
Proto-oncogene tyrosine-protein kinase Src

2

10

Small-scale

0.743

High

1046385

TRIB3
Tribbles homolog 3

1

2

Small-scale

0.740

High

499265

KIT
Mast/stem cell growth factor receptor Kit

1

9

Small-scale

0.724

High

863770

LIMK1
LIM domain kinase 1

1

18

Small-scale

0.713

High

1046375

MIB1
E3 ubiquitin-protein ligase MIB1

1

5

High-throughput

0.691

High

1046367

KGP1
cGMP-dependent protein kinase 1

1

7

Small-scale

0.665

High

800776

MK08
Mitogen-activated protein kinase 8

1

10

High-throughput

0.656

High

233940

GDF9
Growth/differentiation factor 9

1

20

Small-scale

0.647

High

313008

BMP10
Bone morphogenetic protein 10

1

20

Small-scale

0.647

High

439887

INHBA
Inhibin beta A chain

1

20

Small-scale

0.647

High

451821

INHBB
Inhibin beta B chain

1

20

Small-scale

0.647

High

1046371

GDF6
Growth/differentiation factor 6

1

20

Small-scale

0.647

High

1046381

MRAP2
Melanocortin-2 receptor accessory protein 2

2

5

High-throughput

0.628

High

738450

ACV1B
Activin receptor type-1B

1

20

Small-scale

0.621

High

120428

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

348655

RASN
GTPase NRas

1

4

High-throughput

0.618

High

349310

RASH
GTPase HRas

1

4

High-throughput

0.618

High

350158

RASK
GTPase KRas

1

4

High-throughput

0.618

High

436293

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

545365

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

564520

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

602932

BMP6
Bone morphogenetic protein 6

1

20

Small-scale

0.618

High

646032

AVR2A
Activin receptor type-2A

1

20

Small-scale

0.618

High

793306

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.618

High

841194

CDK7
Cyclin-dependent kinase 7

1

3

High-throughput

0.618

High

852467

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

892361

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

893991

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

900458

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

901153

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.618

High

915666

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

925266

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

950982

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

1046365

BMPR2
Bone morphogenetic protein receptor type-2

1

20

Small-scale

0.618

High

1046369

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

1046373

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

1046380

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.618

High

1046384

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.618

High

1046386

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

1046387

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

239984

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

9

High-throughput

0.575

High

1046383

LRIQ1
Leucine-rich repeat and IQ domain-containing protein 1

2

20

High-throughput

0.574

High

1046388

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

20

Small-scale

0.561

High

1046368

FHL2
Four and a half LIM domains protein 2

1

4

Small-scale

0.552

High

728477

MYH11
Myosin-11

1

1

High-throughput

0.536

High

1046377

NRSN1
Neurensin-1

1

2

High-throughput

0.536

High

1046378

RN149
E3 ubiquitin-protein ligase RNF149

1

10

High-throughput

0.536

High

1046379

MARH1
E3 ubiquitin-protein ligase MARCHF1

1

8

High-throughput

0.536

High

1046392

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

5

High-throughput

0.536

High

1046390

ASC
Apoptosis-associated speck-like protein containing a CARD

1

0

Small-scale

0.513

High

526890

TDGF1
Protein Cripto

1

7

Small-scale

0.501

High

569078

DESM
Desmin

1

1

High-throughput

0.489

High

1046374

ARMD4
Armadillo-like helical domain-containing protein 4

1

1

High-throughput

0.489

High

1046382

RUSF1
RUS family member 1

1

3

High-throughput

0.489

High

1046391

RNF11
RING finger protein 11

1

14

High-throughput

0.489

High

737797

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

9

Small-scale

0.481

High

167361

SMAD7
Mothers against decapentaplegic homolog 7

1

20

Small-scale

0.479

High

205376

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.479

High

206959

SMAD6
Mothers against decapentaplegic homolog 6

1

20

Small-scale

0.479

High

207314

FRS3
Fibroblast growth factor receptor substrate 3

1

2

Small-scale

0.479

High

521920

CADH1
Cadherin-1

1

9

High-throughput

0.479

High

555142

CD44
CD44 antigen

1

2

Small-scale

0.479

High

571125

EGLN
Endoglin

1

12

Small-scale

0.479

High

702761

CADH5
Cadherin-5

1

7

Small-scale

0.479

High

814250

GLR
Glucagon receptor

1

1

Small-scale

0.479

High

909545

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.479

High

957700

XIAP
E3 ubiquitin-protein ligase XIAP

1

11

Small-scale

0.479

High

974810

CAV1
Caveolin-1

1

7

Small-scale

0.479

High

1046370

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

0

Small-scale

0.460

High

359014

CRYAB
Alpha-crystallin B chain

1

0

Small-scale

0.458

High

919966

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

588296

FST
Follistatin

1

5

Small-scale

0.445

High

1046366

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

3

High-throughput

0.445

High

1046376

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

Small-scale

0.438

High

1046372

EST3
Carboxylesterase 3

1

2

Small-scale

0.437

High

928596

DYLT1
Dynein light chain Tctex-type 1

1

0

Small-scale

0.261

Low


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Last updated: 15 Jul 2024