Protein: TMTC3
Protein O-mannosyl-transferase TMTC3 (EC 2.4.1.109) (Protein SMILE) (Transmembrane O-mannosyltransferase targeting cadherins 3) (Transmembrane and tetratricopeptide repeat-containing 3)

Gene: TMTC3
Organism: Homo sapiens
Interactions: 91
UniProt ID: Q6ZXV5

Gene Ontology (top 5):
GO:0000030 - mannosyltransferase activity
GO:0004169 - dolichyl-phosphate-mannose-protein mannosyltransferase activity
GO:0005783 - endoplasmic reticulum
GO:0016020 - membrane
GO:0034976 - response to endoplasmic reticulum stress

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

702774

CADH5
Cadherin-5

2

8

High-throughput

0.628

High

1161877

NCEH1
Neutral cholesterol ester hydrolase 1

2

1

High-throughput

0.628

High

1173515

SCN3B
Sodium channel regulatory subunit beta-3

2

2

High-throughput

0.628

High

925380

RAC1
Ras-related C3 botulinum toxin substrate 1

1

3

High-throughput

0.618

High

970273

NRG1
Pro-neuregulin-1, membrane-bound isoform

1

2

High-throughput

0.618

High

1028069

DNJC3
DnaJ homolog subfamily C member 3

1

19

High-throughput

0.618

High

1114489

ZACN
Ligand-gated cation channel ZACN

3

7

High-throughput

0.609

High

1173496

5HT3C
5-hydroxytryptamine receptor 3C

3

6

High-throughput

0.609

High

802339

5HT3A
5-hydroxytryptamine receptor 3A

2

6

High-throughput

0.574

High

989624

ACHD
Acetylcholine receptor subunit delta

2

4

High-throughput

0.574

High

1173488

LYZL2
Lysozyme-like protein 2

2

1

High-throughput

0.574

High

120504

RHOD
Rho-related GTP-binding protein RhoD

1

7

High-throughput

0.553

High

852528

RND2
Rho-related GTP-binding protein RhoN

1

8

High-throughput

0.553

High

900614

RHOA
Transforming protein RhoA

1

4

High-throughput

0.553

High

915775

RHOB
Rho-related GTP-binding protein RhoB

1

4

High-throughput

0.553

High

1173508

RHOJ
Rho-related GTP-binding protein RhoJ

1

4

High-throughput

0.553

High

1173510

RHOF
Rho-related GTP-binding protein RhoF

1

6

High-throughput

0.553

High

570851

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

4

High-throughput

0.536

High

654463

CALX
Calnexin

1

9

High-throughput

0.536

High

677144

ACHB4
Neuronal acetylcholine receptor subunit beta-4

1

4

High-throughput

0.536

High

798506

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

4

High-throughput

0.536

High

1173500

CCD47
PAT complex subunit CCDC47

1

1

High-throughput

0.536

High

1173503

CREL1
Protein disulfide isomerase CRELD1

1

4

High-throughput

0.536

High

1173511

SDF2L
Stromal cell-derived factor 2-like protein 1

1

2

High-throughput

0.536

High

1173520

FBX2
F-box only protein 2

1

1

High-throughput

0.536

High

1173521

TRHDE
Thyrotropin-releasing hormone-degrading ectoenzyme

1

2

High-throughput

0.536

High

1173525

LAMC3
Laminin subunit gamma-3

1

3

High-throughput

0.536

High

1173504

CALR3
Calreticulin-3

2

9

High-throughput

0.533

High

269159

DAB1
Disabled homolog 1

1

1

High-throughput

0.523

High

1173507

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

636363

DNJB1
DnaJ homolog subfamily B member 1

1

20

High-throughput

0.489

High

685260

CEAM8
Carcinoembryonic antigen-related cell adhesion molecule 8

1

2

High-throughput

0.489

High

1045084

LAMB3
Laminin subunit beta-3

1

3

High-throughput

0.489

High

1173490

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.489

High

1173499

GGH
Gamma-glutamyl hydrolase

1

2

High-throughput

0.489

High

1173523

PCDB7
Protocadherin beta-7

1

9

High-throughput

0.489

High

1173524

PCDB1
Protocadherin beta-1

1

8

High-throughput

0.489

High

133541

NOP56
Nucleolar protein 56

1

5

High-throughput

0.479

High

216259

CALU
Calumenin

1

6

High-throughput

0.479

High

227849

PRKN
E3 ubiquitin-protein ligase parkin

1

16

High-throughput

0.479

High

377420

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

386974

P53
Cellular tumor antigen p53

1

6

High-throughput

0.479

High

502252

BIP
Endoplasmic reticulum chaperone BiP

1

20

High-throughput

0.479

High

531878

PDIA4
Protein disulfide-isomerase A4

1

17

High-throughput

0.479

High

871030

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

1

5

High-throughput

0.479

High

890222

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.479

High

917480

H4
Histone H4

1

2

High-throughput

0.479

High

1087952

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

3

High-throughput

0.479

High

1101926

TECT1
Tectonic-1

1

3

High-throughput

0.479

High

1168551

SYNE3
Nesprin-3

1

4

High-throughput

0.479

High

1173491

DJC10
DnaJ homolog subfamily C member 10

1

20

High-throughput

0.479

High

1173494

EMC1
ER membrane protein complex subunit 1

1

2

High-throughput

0.479

High

1173498

AKAP1
A-kinase anchor protein 1, mitochondrial

1

7

High-throughput

0.479

High

1173501

LRC59
Leucine-rich repeat-containing protein 59

1

6

High-throughput

0.479

High

1173502

PLD4
5'-3' exonuclease PLD4

1

5

High-throughput

0.479

High

1173517

VAPA
Vesicle-associated membrane protein-associated protein A

1

2

High-throughput

0.479

High

1173518

DJB11
DnaJ homolog subfamily B member 11

1

20

High-throughput

0.479

High

1173522

MTMR7
Myotubularin-related protein 7

1

5

High-throughput

0.479

High

1164738

ANR12
Ankyrin repeat domain-containing protein 12

1

7

High-throughput

0.470

High

1173512

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

205573

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.437

High

253263

KI21B
Kinesin-like protein KIF21B

1

4

High-throughput

0.437

High

360076

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

9

High-throughput

0.437

High

553015

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.437

High

637266

CATS
Cathepsin S

1

2

High-throughput

0.437

High

651518

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

7

High-throughput

0.437

High

720763

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

941080

RNF4
E3 ubiquitin-protein ligase RNF4

1

3

High-throughput

0.437

High

941860

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

1

4

High-throughput

0.437

High

1156616

TECT3
Tectonic-3

1

3

High-throughput

0.437

High

1165702

LMBRL
Protein LMBR1L

1

3

High-throughput

0.437

High

1166832

LRC31
Leucine-rich repeat-containing protein 31

1

4

High-throughput

0.437

High

1170521

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.437

High

1173489

PLD3
5'-3' exonuclease PLD3

1

5

High-throughput

0.437

High

1173492

SRRM1
Serine/arginine repetitive matrix protein 1

1

5

High-throughput

0.437

High

1173505

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

20

High-throughput

0.437

High

1173506

SPRTN
DNA-dependent metalloprotease SPRTN

1

1

High-throughput

0.437

High

1173509

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.437

High

1173513

FBX6
F-box only protein 6

1

1

High-throughput

0.437

High

1173514

T106B
Transmembrane protein 106B

1

2

High-throughput

0.437

High

1173516

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.437

High

1173519

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.437

High

965244

DEF5
Defensin alpha 5

2

0

High-throughput

0.328

High

217092

NKG2F
NKG2-F type II integral membrane protein

1

0

High-throughput

0.279

Low

474734

CFC1
Cryptic protein

1

0

High-throughput

0.279

Low

1060413

KI2S3
Killer cell immunoglobulin-like receptor 2DS3

1

0

High-throughput

0.279

Low

1165566

ENPP6
Glycerophosphocholine cholinephosphodiesterase ENPP6

1

0

High-throughput

0.249

Low

1173493

SYNE4
Nesprin-4

1

0

High-throughput

0.249

Low

1173495

CGAS
Cyclic GMP-AMP synthase

1

0

Small-scale

0.249

Low

1173497

DNS2B
Deoxyribonuclease-2-beta

1

0

High-throughput

0.249

Low

209256

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024