Protein: Q9VJW9
ADAM10 endopeptidase (EC 3.4.24.81)

Gene: Q9VJW9, kuz
Organism: Drosophila melanogaster
Interactions: 85
UniProt ID: Q9VJW9

Gene Ontology (top 5):
GO:0003007 - heart morphogenesis
GO:0004222 - metalloendopeptidase activity
GO:0005886 - plasma membrane
GO:0006509 - membrane protein ectodomain proteolysis
GO:0007219 - Notch signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1478805

Q9W4X6
Tetraspanin

1

20

Small-scale

0.665

High

451885

NOTCH
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]

1

15

Small-scale

0.501

High

517435

DL
Neurogenic locus protein delta

1

17

Small-scale

0.501

High

233550

SPY
Protein sprouty

1

2

High-throughput

0.481

High

852518

CADF
Cofilin/actin-depolymerizing factor homolog

1

0

High-throughput

0.464

High

263067

TENM
Teneurin-m

1

15

High-throughput

0.445

High

598287

PTP69
Tyrosine-protein phosphatase 69D

1

6

High-throughput

0.445

High

663800

SLIT
Protein slit

1

14

High-throughput

0.445

High

1262076

Q7JV09
GH28348p

1

2

High-throughput

0.445

High

1263325

Q7JY94
Ubiquitin-like modifier-activating enzyme ATG7

1

1

High-throughput

0.445

High

1266691

DAT
Sodium-dependent dopamine transporter

1

1

High-throughput

0.445

High

1269719

Q7KU92
Ankyrin 2, isoform L

1

2

High-throughput

0.445

High

1466585

Q9V8V8
MAP/microtubule affinity-regulating kinase 3

1

1

High-throughput

0.445

High

1473298

SULF1
Extracellular sulfatase SULF-1 homolog

1

4

High-throughput

0.445

High

1478771

C2D1
Coiled-coil and C2 domain-containing protein 1-like

1

6

High-throughput

0.445

High

1478781

Q9VV68
adenylate cyclase

1

1

High-throughput

0.445

High

1478782

NEDD4
E3 ubiquitin-protein ligase Nedd-4

1

2

High-throughput

0.445

High

1478797

Q9W3H8
Protein PALS1

1

12

High-throughput

0.445

High

1478806

Q9W4Y4
Terribly reduced optic lobes, isoform AN

1

4

High-throughput

0.445

High

235118

O46231
FI18705p1

1

2

High-throughput

0.442

High

264618

KPYK
Pyruvate kinase

1

1

High-throughput

0.442

High

1321886

Q8MYR8
RH74685p

1

2

High-throughput

0.442

High

197994

AMYR
Alpha-amylase-related protein

1

0

High-throughput

0.426

High

1471818

NAA25
Phagocyte signaling-impaired protein

1

0

High-throughput

0.426

High

1478770

MPND
MPN domain-containing protein CG4751

1

0

High-throughput

0.426

High

1478772

Q9VLD9
Taiman, isoform C

1

0

High-throughput

0.426

High

1478776

Q9VP78
GH23156p

1

0

High-throughput

0.426

High

1478788

Q9VYY5
Potassium channel domain-containing protein

1

0

High-throughput

0.426

High

1478793

Q9W1G7
LD21576p

1

0

High-throughput

0.426

High

1478795

Q9W269
Solute carrier organic anion transporter family member

1

0

High-throughput

0.426

High

56680

A1ZAD3
Uncharacterized protein

1

3

High-throughput

0.407

High

95572

E2QCZ5
FHA domain-containing protein

1

1

High-throughput

0.407

High

663999

PHB1
Prohibitin 1

1

4

High-throughput

0.407

High

1069193

Q0E8E8
Phosphate carrier protein, mitochondrial

1

2

High-throughput

0.407

High

1175681

XPC
DNA repair protein complementing XP-C cells homolog

1

7

High-throughput

0.407

High

1262238

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

2

High-throughput

0.407

High

1267504

Q7KMH9
BcDNA.LD26050

1

7

High-throughput

0.407

High

1267671

Q7KMP8
26S proteasome non-ATPase regulatory subunit 13

1

2

High-throughput

0.407

High

1304675

Q8IPN8
Oxidation resistance protein 1

1

1

High-throughput

0.407

High

1305221

Q8IQ71
Dikar, isoform C

1

7

High-throughput

0.407

High

1378337

Q95TT5
LD24616p

1

12

High-throughput

0.407

High

1463381

Q9V3E7
LD24793p

1

1

High-throughput

0.407

High

1465790

HCF
Host cell factor

1

1

High-throughput

0.407

High

1470137

Q9VC96
BRWD3

1

2

High-throughput

0.407

High

1471613

Q9VDI8
Syncrip, isoform D

1

1

High-throughput

0.407

High

1473752

Q9VFD3
Uncharacterized protein, isoform B

1

4

High-throughput

0.407

High

1476704

Q9VHT2
FI07663p

1

1

High-throughput

0.407

High

1477064

Q9VI14
GH12404p

1

8

High-throughput

0.407

High

1477616

Q9VIJ9
Guanine nucleotide-binding protein-like 1

1

2

High-throughput

0.407

High

1478773

Q9VMS2
Nuclear receptor coactivator 6, isoform C

1

4

High-throughput

0.407

High

1478774

Q9VN57
Coiled-coil domain-containing protein 39

1

3

High-throughput

0.407

High

1478775

Q9VNZ7
LD44094p

1

2

High-throughput

0.407

High

1478777

Q9VQL0
Uncharacterized protein, isoform B

1

1

High-throughput

0.407

High

1478779

Q9VUC1
Hsc70Cb, isoform A

1

1

High-throughput

0.407

High

1478784

Q9VWC0
Histone gene-specific epigenetic repressor in late S phase, isoform A

1

4

High-throughput

0.407

High

1478787

TENA
Teneurin-a

1

17

High-throughput

0.407

High

1478789

SAHH2
Adenosylhomocysteinase-like 1

1

1

High-throughput

0.407

High

1478790

LYST
Lysosomal-trafficking regulator

1

1

High-throughput

0.407

High

1478794

KI59C
Kinesin-like protein Klp59C

1

1

High-throughput

0.407

High

1478796

Q9W325
HECT-type E3 ubiquitin transferase

1

2

High-throughput

0.407

High

1478799

Q9W414
Regulatory particle triple-A ATPase 4

1

1

High-throughput

0.407

High

1478801

Q9W472
GH14380p

1

3

High-throughput

0.407

High

1478802

Q9W475
LP17541p

1

1

High-throughput

0.407

High

1478803

Q9W4H6
Pyruvate dehydrogenase E1 component subunit alpha

1

2

High-throughput

0.407

High

1478804

NSUN2
tRNA

1

1

High-throughput

0.407

High

875290

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low

1236552

Q6NLM8
RE56731p

1

0

High-throughput

0.232

Low

1269554

Q7KTW9
Asparagine synthetase [glutamine-hydrolyzing]

1

0

High-throughput

0.232

Low

1285584

Q86BI3
Zinc-finger protein at 72D, isoform B

1

0

High-throughput

0.232

Low

1304812

Q8IPU8
BNIP3, isoform B

1

0

High-throughput

0.232

Low

1374442

AT5F1
ATP synthase subunit b, mitochondrial

1

0

High-throughput

0.232

Low

1466727

Q9V9P7
FI08016p

1

0

High-throughput

0.232

Low

1468845

UNC80
Protein unc-80 homolog

1

0

High-throughput

0.232

Low

1470141

Q9VCA1
monoamine oxidase

1

0

High-throughput

0.232

Low

1477285

Q9VIA6
LP11585p

1

0

High-throughput

0.232

Low

1478778

Q9VRC8
Uncharacterized protein, isoform A

1

0

High-throughput

0.232

Low

1478780

Q9VUZ0
Translocon-associated protein subunit beta

1

0

High-throughput

0.232

Low

1478783

Q9VWA5
Uncharacterized protein

1

0

High-throughput

0.232

Low

1478785

Q9VXP5
EF-hand domain containing 1.1

1

0

High-throughput

0.232

Low

1478786

Q9VY54
RNA helicase

1

0

High-throughput

0.232

Low

1478791

Q9W0Z4
LD44910p

1

0

High-throughput

0.232

Low

1478792

INT1
Integrator complex subunit 1

1

0

High-throughput

0.232

Low

1478798

Q9W3R9
FI03239p

1

0

High-throughput

0.232

Low

1478800

SPT6H
Transcription elongation factor SPT6

1

0

High-throughput

0.232

Low

1478807

PYG
Glycogen phosphorylase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025