Protein: MRCKB
Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (CDC42BP-beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta)

Gene: MRCKB, CDC42BPB
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q9Y5S2

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

894628

CDC42
Cell division control protein 42 homolog

4

20

High-throughput

0.900

High

1137917

MRCKA
Serine/threonine-protein kinase MRCK alpha

2

19

High-throughput

0.817

High

983951

KPCZ
Protein kinase C zeta type

2

20

High-throughput

0.811

High

1345713

INKA2
PAK4-inhibitor INKA2

3

1

High-throughput

0.770

High

674826

GRPR
Gastrin-releasing peptide receptor

2

0

High-throughput

0.770

High

350729

RASK
GTPase KRas

2

20

High-throughput

0.754

High

916101

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

1026844

MP2K5
Dual specificity mitogen-activated protein kinase kinase 5

1

20

High-throughput

0.698

High

1038347

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

18

High-throughput

0.698

High

1062093

UBX2B
UBX domain-containing protein 2B

4

1

High-throughput

0.694

High

931958

CSK2B
Casein kinase II subunit beta

1

3

High-throughput

0.691

High

728677

PPM1A
Protein phosphatase 1A

1

6

Small-scale

0.647

High

120735

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

165745

SET1A
Histone-lysine N-methyltransferase SETD1A

1

8

High-throughput

0.618

High

349030

RASN
GTPase NRas

1

20

High-throughput

0.618

High

375162

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

19

High-throughput

0.618

High

385802

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

411908

LCK
Tyrosine-protein kinase Lck

1

19

High-throughput

0.618

High

434101

LYN
Tyrosine-protein kinase Lyn

1

19

High-throughput

0.618

High

435195

SP1
Transcription factor Sp1

1

7

Small-scale

0.618

High

538459

ENPL
Endoplasmin

1

20

High-throughput

0.618

High

545725

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

564758

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

617154

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

4

High-throughput

0.618

High

793543

MUC18
Cell surface glycoprotein MUC18

1

14

High-throughput

0.618

High

852694

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

892702

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

901094

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

901284

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.618

High

925766

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

951494

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

974716

MECOM
Histone-lysine N-methyltransferase MECOM

1

5

High-throughput

0.618

High

1070480

RAB35
Ras-related protein Rab-35

1

10

High-throughput

0.618

High

1071723

KS6A2
Ribosomal protein S6 kinase alpha-2

1

19

High-throughput

0.618

High

1076834

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

1086089

CDKN3
Cyclin-dependent kinase inhibitor 3

1

2

Small-scale

0.618

High

1169516

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

12

High-throughput

0.618

High

1172454

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

1183627

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

1296775

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.618

High

1315178

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

3

High-throughput

0.618

High

1330459

DNJC5
DnaJ homolog subfamily C member 5

1

8

High-throughput

0.618

High

1331011

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

1331749

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.618

High

1335421

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

1296578

F167A
Protein FAM167A

3

2

High-throughput

0.616

High

1354183

HDAC6
Histone deacetylase 6

2

12

High-throughput

0.611

High

1217032

LUR1L
Leucine rich adaptor protein 1-like

3

8

High-throughput

0.609

High

1268126

MY18A
Unconventional myosin-XVIIIa

2

20

Small-scale

0.601

High

1297344

LURA1
Leucine rich adaptor protein 1

2

8

Small-scale

0.601

High

240310

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

8

High-throughput

0.575

High

1200039

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

13

High-throughput

0.575

High

370819

ESR1
Estrogen receptor

2

14

High-throughput

0.571

High

1166896

LRC31
Leucine-rich repeat-containing protein 31

1

6

High-throughput

0.553

High

506281

PYGM
Glycogen phosphorylase, muscle form

1

1

High-throughput

0.541

High

883740

WDR4
tRNA

1

15

High-throughput

0.541

High

179287

COPT1
High affinity copper uptake protein 1

1

1

High-throughput

0.536

High

331421

APBA3
Amyloid-beta A4 precursor protein-binding family A member 3

1

20

High-throughput

0.536

High

659748

RXRB
Retinoic acid receptor RXR-beta

1

10

High-throughput

0.536

High

858688

PPP5
Serine/threonine-protein phosphatase 5

1

16

High-throughput

0.536

High

1069582

TEBP
Prostaglandin E synthase 3

1

2

High-throughput

0.536

High

1235400

KCD17
BTB/POZ domain-containing protein KCTD17

1

6

High-throughput

0.536

High

1310720

SIKE1
Suppressor of IKBKE 1

1

2

High-throughput

0.536

High

1335455

BEX1
Protein BEX1

1

2

High-throughput

0.536

High

1357714

TRI35
E3 ubiquitin-protein ligase TRIM35

1

8

High-throughput

0.536

High

760417

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.515

High

946632

DCD
Dermcidin

1

1

High-throughput

0.515

High

1274489

H2B1H
Histone H2B type 1-H

1

17

High-throughput

0.515

High

1299960

FMNL2
Formin-like protein 2

1

6

High-throughput

0.515

High

931058

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

12

Small-scale

0.501

High

1234886

TTC9C
Tetratricopeptide repeat protein 9C

1

7

High-throughput

0.489

High

279775

FLOT1
Flotillin-1

1

8

High-throughput

0.479

High

309192

KI20A
Kinesin-like protein KIF20A

1

13

High-throughput

0.479

High

323374

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

5

High-throughput

0.479

High

567346

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

648948

DPP4
Dipeptidyl peptidase 4

1

2

High-throughput

0.479

High

742635

SYUA
Alpha-synuclein

1

3

High-throughput

0.479

High

790637

RL35
Large ribosomal subunit protein uL29

1

1

High-throughput

0.479

High

886228

H2B1D
Histone H2B type 1-D

1

17

High-throughput

0.479

High

959802

VIGLN
Vigilin

1

13

High-throughput

0.479

High

990961

ZO1
Tight junction protein ZO-1

1

20

Small-scale

0.479

High

1042944

CUL3
Cullin-3

1

6

High-throughput

0.479

High

1084256

OCLN
Occludin

1

6

High-throughput

0.479

High

1201957

TAXB1
Tax1-binding protein 1

1

19

High-throughput

0.479

High

1231043

K2C78
Keratin, type II cytoskeletal 78

1

2

High-throughput

0.479

High

1233627

ARL14
ADP-ribosylation factor-like protein 14

1

12

High-throughput

0.479

High

1270038

ESR2
Estrogen receptor beta

1

14

High-throughput

0.479

High

1281519

FBXW7
F-box/WD repeat-containing protein 7

1

15

High-throughput

0.479

High

1283117

CK052
Uncharacterized protein C11orf52

1

2

High-throughput

0.479

High

1344196

DDX21
Nucleolar RNA helicase 2

1

17

High-throughput

0.479

High

1355018

ZRAN1
Ubiquitin thioesterase ZRANB1

1

13

High-throughput

0.479

High

1376959

MTMR7
Myotubularin-related protein 7

1

6

High-throughput

0.479

High

1255244

BRX1
Ribosome biogenesis protein BRX1 homolog

1

4

High-throughput

0.470

High

1344874

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.457

High

529968

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High

882665

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

19

High-throughput

0.445

High

1129870

H2B2F
Histone H2B type 2-F

1

17

High-throughput

0.445

High

1146002

CP135
Centrosomal protein of 135 kDa

1

20

High-throughput

0.445

High

1233294

RYBP
RING1 and YY1-binding protein

1

5

High-throughput

0.445

High

554170

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.437

High

721897

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.437

High

1189119

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.437

High

1292419

FA89A
Protein FAM89A

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024