Protein: Q9VGU4
FI02822p (Leash)

Gene: Q9VGU4, Leash
Organism: Drosophila melanogaster
Interactions: 231
UniProt ID: Q9VGU4

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0015031 - protein transport
GO:0031410 - cytoplasmic vesicle
GO:0031625 - ubiquitin protein ligase binding
GO:0035332 - positive regulation of hippo signaling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1475182

Q9VGU4
FI02822p

2

15

High-throughput

0.767

High

1445307

Q9NCC3
Sorting nexin

1

2

High-throughput

0.691

High

1445617

VAV
Protein vav

1

6

High-throughput

0.691

High

264438

O62530
Adaptor protein complex 2, mu subunit, isoform A

3

2

High-throughput

0.660

High

1192909

YAP1
Transcriptional coactivator yorkie

3

20

Small-scale

0.656

High

691936

CAND
Calpain-D

2

1

High-throughput

0.594

High

1475192

COG5
Conserved oligomeric Golgi complex subunit 5

2

0

High-throughput

0.569

High

1475271

X2JCT5
Insulin receptor substrate 53 kDa, isoform E

1

4

High-throughput

0.553

High

912341

UBCD2
Ubiquitin-conjugating enzyme E2-24 kDa

2

7

High-throughput

0.542

High

1475255

Q9W329
Golgi-localized, gamma-adaptin ear containing, ARF binding protein

2

9

High-throughput

0.542

High

54622

A1Z8U0
Pre-mRNA-processing-splicing factor 8

1

4

High-throughput

0.536

High

195771

COS
Kinesin-like protein costa

1

2

High-throughput

0.536

High

198085

PRS8
26S proteasome regulatory subunit 8

1

8

High-throughput

0.536

High

303785

DCO
Discs overgrown protein kinase

1

7

High-throughput

0.536

High

304534

AUB
Protein aubergine

1

3

High-throughput

0.536

High

467132

CSK2A
Casein kinase II subunit alpha

1

7

High-throughput

0.536

High

661871

FUSED
Serine/threonine-protein kinase fused

1

8

High-throughput

0.536

High

718351

TOP1
DNA topoisomerase 1

1

9

High-throughput

0.536

High

889892

DOA
Serine/threonine-protein kinase Doa

1

4

High-throughput

0.536

High

911771

POLO
Serine/threonine-protein kinase polo

1

6

High-throughput

0.536

High

929309

KC1A
Casein kinase I isoform alpha

1

10

High-throughput

0.536

High

933579

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

4

High-throughput

0.536

High

938888

FAF
Probable ubiquitin carboxyl-terminal hydrolase FAF

1

8

High-throughput

0.536

High

1019509

AP2A
AP-2 complex subunit alpha

1

12

High-throughput

0.536

High

1174763

MERH
Moesin/ezrin/radixin homolog 2

1

9

High-throughput

0.536

High

1197203

RBP9X
Ran-binding proteins 9/10 homolog

1

7

High-throughput

0.536

High

1216770

ACAD9
Complex I assembly factor Egm, mitochondrial

1

3

High-throughput

0.536

High

1264232

WDR26
WD repeat-containing protein 26 homolog

1

6

High-throughput

0.536

High

1265742

Q7K3H0
LD28067p

1

14

High-throughput

0.536

High

1320978

BRAT
Protein brain tumor

1

6

High-throughput

0.536

High

1321192

Q8MSB1
E3 ubiquitin-protein transferase MAEA

1

4

High-throughput

0.536

High

1345430

HIPPO
Serine/threonine-protein kinase hippo

1

8

High-throughput

0.536

High

1463443

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

3

High-throughput

0.536

High

1464443

Q9V3V6
26S proteasome regulatory complex subunit p50

1

9

High-throughput

0.536

High

1464793

Q9V3Z4
GH11341p

1

2

High-throughput

0.536

High

1466460

SMUF1
E3 ubiquitin-protein ligase Smurf1

1

20

High-throughput

0.536

High

1468596

Q9VAX8
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.536

High

1472247

Q9VE18
WD40 repeat-containing protein SMU1

1

9

High-throughput

0.536

High

1473893

KIBRA
Protein kibra

1

20

High-throughput

0.536

High

1475098

Y6693
J domain-containing protein CG6693

1

4

High-throughput

0.536

High

1475184

Q9VHC0
LD23870p

1

6

High-throughput

0.536

High

1475189

Q9VI72
Spindle assembly abnormal 4

1

4

High-throughput

0.536

High

1475190

Q9VJ12
Acinus, isoform A

1

11

High-throughput

0.536

High

1475212

HERC2
Probable E3 ubiquitin-protein ligase HERC2

1

20

High-throughput

0.536

High

1475223

Q9VVA7
Tumor suppressor protein 101

1

4

High-throughput

0.536

High

1475232

Q9VWH7
6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase long form

1

3

High-throughput

0.536

High

1475234

Q9VWS1
Houki

1

4

High-throughput

0.536

High

1475237

Q9VXR3
HECT-type E3 ubiquitin transferase

1

20

High-throughput

0.536

High

1475259

Q9W437
Raptor, isoform B

1

4

High-throughput

0.536

High

1475261

RNP4F
RNA-binding protein 4F

1

5

High-throughput

0.536

High

1475268

Q9XZ61
Ubiquitin carboxyl-terminal hydrolase

1

1

High-throughput

0.536

High

1475270

SUDX
E3 ubiquitin-protein ligase Su(dx)

1

20

High-throughput

0.536

High

1305346

Q8IQE6
Insulin receptor substrate 53 kDa, isoform A

1

8

High-throughput

0.514

High

878615

MGN
Protein mago nashi

1

0

High-throughput

0.513

High

1019567

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

1

0

High-throughput

0.513

High

1262428

WASH1
WASH complex subunit 1

1

0

High-throughput

0.513

High

1473654

CYFIP
Cytoplasmic FMR1-interacting protein

1

0

High-throughput

0.513

High

1475199

WASC3
WASH complex subunit 3

1

0

High-throughput

0.513

High

1475221

WASC5
WASH complex subunit homolog 5

1

0

High-throughput

0.513

High

1475235

Q9VWY7
Multivesicular body subunit 12A

1

0

High-throughput

0.513

High

1475236

WASC4
WASH complex subunit 4

1

0

High-throughput

0.513

High

47794

A0AQH0
Proteasome subunit beta

1

6

High-throughput

0.489

High

55548

SYF1
Pre-mRNA-splicing factor syf1 homolog

1

9

High-throughput

0.489

High

55817

A1Z9K0
Uncharacterized protein, isoform B

1

9

High-throughput

0.489

High

55918

DHX8
ATP-dependent RNA helicase DHX8

1

8

High-throughput

0.489

High

58590

WASC2
WASH complex subunit 2

1

11

High-throughput

0.489

High

196057

O17432
Cyclin-dependent kinase 9

1

13

High-throughput

0.489

High

234945

PGAM5
Serine/threonine-protein phosphatase Pgam5, mitochondrial

1

2

High-throughput

0.489

High

235054

NOI
Splicing factor 3A subunit 3

1

2

High-throughput

0.489

High

355774

CCNT
Cyclin-T

1

4

High-throughput

0.489

High

567644

FSH
Homeotic protein female sterile

1

9

High-throughput

0.489

High

609131

CRN
Protein crooked neck

1

10

High-throughput

0.489

High

666622

MLE
Dosage compensation regulator mle

1

10

High-throughput

0.489

High

669724

PSMD3
Probable 26S proteasome non-ATPase regulatory subunit 3

1

1

High-throughput

0.489

High

821902

PSA2
Proteasome subunit alpha type-2

1

3

High-throughput

0.489

High

822082

PSB1
Proteasome subunit beta type-1

1

10

High-throughput

0.489

High

875015

PRS4
26S proteasome regulatory subunit 4

1

10

High-throughput

0.489

High

936254

HEM
Membrane-associated protein Hem

1

1

High-throughput

0.489

High

1024294

LAMA
Laminin subunit alpha

1

5

High-throughput

0.489

High

1173121

Q24253
AP complex subunit beta

1

13

High-throughput

0.489

High

1208007

SET1
Histone-lysine N-methyltransferase SETD1

1

1

High-throughput

0.489

High

1261838

Q7JRH5
RE28271p

1

2

High-throughput

0.489

High

1261863

EAF
Ell-associated factor Eaf

1

1

High-throughput

0.489

High

1262318

BRDH
Bromodomain-containing protein homolog

1

3

High-throughput

0.489

High

1263525

Q7JZ62
RE57120p

1

4

High-throughput

0.489

High

1264708

Q7K148
Proteasome subunit beta

1

6

High-throughput

0.489

High

1265960

DHX15
ATP-dependent RNA helicase DHX15 homolog

1

8

High-throughput

0.489

High

1266554

NCBP1
Nuclear cap-binding protein subunit 1

1

4

High-throughput

0.489

High

1267597

ACOX1
Acyl-coenzyme A oxidase 1

1

3

High-throughput

0.489

High

1268421

Q7KNF1
Ribonuclease 3

1

3

High-throughput

0.489

High

1269686

CHD1
Chromodomain-helicase-DNA-binding protein 1

1

5

High-throughput

0.489

High

1304526

Q8IPE8
Trifunctional enzyme subunit alpha, mitochondrial

1

2

High-throughput

0.489

High

1377225

Q95RB1
Pre-mRNA-splicing factor RBM22

1

6

High-throughput

0.489

High

1379151

HRS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

8

High-throughput

0.489

High

1463227

CWC15
Protein CWC15 homolog

1

1

High-throughput

0.489

High

1464092

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

5

High-throughput

0.489

High

1464861

Q9V405
26S proteasome regulatory subunit 6B

1

6

High-throughput

0.489

High

1465587

Y9776
Zinc finger matrin-type protein CG9776

1

2

High-throughput

0.489

High

1465912

RU2A
Probable U2 small nuclear ribonucleoprotein A'

1

7

High-throughput

0.489

High

1466064

PSA3
Proteasome subunit alpha type-3

1

2

High-throughput

0.489

High

1466375

SAM50
SAM50-like protein CG7639

1

2

High-throughput

0.489

High

1466651

SRRT
Serrate RNA effector molecule homolog

1

1

High-throughput

0.489

High

1467080

Q9V9V7
LD23072p

1

1

High-throughput

0.489

High

1468357

DCA10
DDB1- and CUL4-associated factor 10 homolog

1

8

High-throughput

0.489

High

1468731

Q9VAY6
Pre-mRNA-splicing factor SPF27

1

1

High-throughput

0.489

High

1468759

Q9VAY9
GH07821p

1

3

High-throughput

0.489

High

1468967

NKAP
NF-kappa-B-activating protein

1

6

High-throughput

0.489

High

1469899

ASP
Protein abnormal spindle

1

6

High-throughput

0.489

High

1470387

Q9VCH1
Eukaryotic translation initiation factor 4G2, isoform A

1

5

High-throughput

0.489

High

1470663

SAV
Scaffold protein salvador

1

20

High-throughput

0.489

High

1471282

Q9VD52
Pre-mRNA-processing factor 17

1

6

High-throughput

0.489

High

1473091

Q9VEP9
Splicing factor 3A subunit 1

1

14

High-throughput

0.489

High

1473310

ATD3A
ATPase family AAA domain-containing protein 3A homolog

1

9

High-throughput

0.489

High

1474681

Q9VGG9
RNA helicase aquarius

1

13

High-throughput

0.489

High

1475185

Q9VHH8
Beag

1

1

High-throughput

0.489

High

1475187

IF4A3
Eukaryotic initiation factor 4A-III

1

7

High-throughput

0.489

High

1475188

Q9VHV6
RE31520p

1

1

High-throughput

0.489

High

1475191

CWC22
Pre-mRNA-splicing factor CWC22 homolog

1

10

High-throughput

0.489

High

1475193

Q9VJJ0
Proteasome subunit beta

1

8

High-throughput

0.489

High

1475196

Q9VLL1
D12

1

3

High-throughput

0.489

High

1475197

KPBB
Probable phosphorylase b kinase regulatory subunit beta

1

1

High-throughput

0.489

High

1475201

Q9VMF3
Dizzy isoform AII

1

7

High-throughput

0.489

High

1475202

Q9VNI8
Hpr1

1

2

High-throughput

0.489

High

1475203

CDK12
Cyclin-dependent kinase 12

1

12

High-throughput

0.489

High

1475204

KP58
Serine/threonine-protein kinase PITSLRE

1

7

High-throughput

0.489

High

1475205

Q9VPL0
U5 small nuclear ribonucleoprotein 40 kDa protein

1

4

High-throughput

0.489

High

1475207

Q9VPR5
Splicing factor 3B subunit 1

1

11

High-throughput

0.489

High

1475208

Q9VQ76
THO complex subunit 2

1

11

High-throughput

0.489

High

1475209

Q9VQF5
Cwc25

1

6

High-throughput

0.489

High

1475210

AFFL
AF4/FMR2 family member lilli

1

5

High-throughput

0.489

High

1475211

Q9VQK7
LD45152p

1

5

High-throughput

0.489

High

1475215

Q9VT61
Ciz1 zinc finger protein, isoform A

1

5

High-throughput

0.489

High

1475216

Q9VTZ7
LD47970p

1

4

High-throughput

0.489

High

1475217

GPTC1
G patch domain-containing protein 1 homolog

1

9

High-throughput

0.489

High

1475218

Q9VUJ1
Proteasome subunit beta

1

6

High-throughput

0.489

High

1475220

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

9

High-throughput

0.489

High

1475224

Q9VVI0
SD09427p

1

5

High-throughput

0.489

High

1475227

Q9VVU6
Pre-mRNA-processing factor 6

1

7

High-throughput

0.489

High

1475228

ELL
RNA polymerase II elongation factor Ell

1

4

High-throughput

0.489

High

1475229

Q9VW70
FI21813p1

1

5

High-throughput

0.489

High

1475230

Q9VWC7
FI02109p

1

12

High-throughput

0.489

High

1475231

Q9VWH5
Uncharacterized protein, isoform A

1

5

High-throughput

0.489

High

1475233

FLACC
Fl(2)d-associated complex component

1

12

High-throughput

0.489

High

1475239

Q9VYQ9
Pleiotropic regulator 1

1

4

High-throughput

0.489

High

1475243

Q9W047
LD30049p

1

1

High-throughput

0.489

High

1475244

Q9W0C5
Iron-sulfur clusters transporter ABCB7, mitochondrial

1

2

High-throughput

0.489

High

1475246

Q9W0Q2
Peptidyl-prolyl cis-trans isomerase

1

3

High-throughput

0.489

High

1475247

Q9W0R0
Cell division cycle 5, isoform A

1

4

High-throughput

0.489

High

1475248

Q9W106
Peroxisomal leader peptide-processing protease

1

2

High-throughput

0.489

High

1475249

Q9W1A9
histone acetyltransferase

1

4

High-throughput

0.489

High

1475250

Q9W1F7
IP15825p

1

6

High-throughput

0.489

High

1475252

Q9W255
GH05812p

1

2

High-throughput

0.489

High

1475253

PI5K1
Phosphatidylinositol 4-phosphate 5-kinase type-1 sktl

1

3

High-throughput

0.489

High

1475258

Q9W414
Regulatory particle triple-A ATPase 4

1

8

High-throughput

0.489

High

1475260

Q9W4C1
IP13321p

1

3

High-throughput

0.489

High

1475262

TI50C
Mitochondrial import inner membrane translocase subunit TIM50-C

1

1

High-throughput

0.489

High

1475263

Q9W4W8
Paraplegin, isoform A

1

8

High-throughput

0.489

High

1475264

Q9W5R5
Sarcolemmal membrane-associated protein

1

5

High-throughput

0.489

High

1475265

Q9W5W8

1

2

High-throughput

0.489

High

1475266

PSB3
Proteasome subunit beta type-3

1

9

High-throughput

0.489

High

1475269

FL2D
Pre-mRNA-splicing regulator female-lethal(2)D

1

5

High-throughput

0.489

High

55677

A1Z9J2
Short stop, isoform C

1

13

High-throughput

0.479

High

68144

A8DY67
Acetyl-CoA carboxylase, isoform E

1

8

High-throughput

0.479

High

92292

D3DML3
Connector of kinase to AP-1, isoform E

1

5

High-throughput

0.479

High

94248

D5SHR3
HECT-type E3 ubiquitin transferase

1

20

High-throughput

0.479

High

94970

E1JGN7
Heterogeneous nuclear ribonucleoprotein K, isoform E

1

5

High-throughput

0.479

High

121633

M9PFR8
Artemis, isoform B

1

20

High-throughput

0.479

High

121658

M9PFW8
Apollo, isoform B

1

20

High-throughput

0.479

High

1269744

Q7KUD4
phospholipase A2

1

4

High-throughput

0.479

High

1275266

Q7YZA0
Trio, isoform B

1

4

High-throughput

0.479

High

1303799

Q8INF6
Hexamethylene bisacetamide inducible, isoform B

1

1

High-throughput

0.479

High

1475225

NEDD4
E3 ubiquitin-protein ligase Nedd-4

1

20

High-throughput

0.479

High

75097

B3DNE9
IP20449p

1

5

High-throughput

0.451

High

1304333

Q8INY6
RH05790p

1

1

High-throughput

0.451

High

55710

A1Z9J3
Short stop, isoform H

1

12

High-throughput

0.445

High

121587

M9PFK2
HECT-type E3 ubiquitin transferase

1

20

High-throughput

0.445

High

757043

FAS2
Fasciclin-2

1

1

High-throughput

0.445

High

1262083

Q7JV23
Acetyl-CoA carboxylase, isoform B

1

8

High-throughput

0.445

High

1267145

Q7KHL0
Bancal protein

1

5

High-throughput

0.445

High

1270020

Q7KVD1
Trio, isoform A

1

9

High-throughput

0.445

High

1440549

Q9I7R5
Apollo, isoform A

1

20

High-throughput

0.445

High

1473900

Q9VFH2
Hexamethylene bisacetamide inducible, isoform A

1

1

High-throughput

0.445

High

1475198

Q9VLS7
LD21067p

1

1

High-throughput

0.445

High

1475200

Q9VLT9
Connector of kinase to AP-1, isoform A

1

7

High-throughput

0.445

High

1475222

Q9VV82
Artemis, isoform A

1

20

High-throughput

0.445

High

1475254

Q9W325
HECT-type E3 ubiquitin transferase

1

20

High-throughput

0.445

High

1475186

Q9VHP3
GEO11133p1

1

5

High-throughput

0.439

High

1475274

X2JEH3
Uncharacterized protein, isoform E

1

1

High-throughput

0.439

High

55158

A1Z936
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

3

High-throughput

0.437

High

68768

A8JQW3
Pinin, isoform B

1

6

High-throughput

0.437

High

95514

E2QCN4
Not1, isoform F

1

9

High-throughput

0.437

High

118636

M9NF18
Uncharacterized protein, isoform D

1

1

High-throughput

0.437

High

120499

M9PD90
Discs large 5, isoform D

1

2

High-throughput

0.437

High

122134

M9PHQ4
Pre-mRNA-splicing factor 38

1

1

High-throughput

0.437

High

1305629

Q8IQQ9
AFG3 like matrix AAA peptidase subunit 2, isoform B

1

9

High-throughput

0.437

High

1475272

X2JDM5
Max-binding protein MNT

1

1

High-throughput

0.437

High

1475273

X2JE07
Uncharacterized protein, isoform D

1

9

High-throughput

0.437

High

55156

A1Z935
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

3

High-throughput

0.407

High

68201

A8DY81
Not1, isoform C

1

9

High-throughput

0.407

High

1344199

Q8SY46
Max-binding protein MNT

1

1

High-throughput

0.407

High

1346061

Q8T4G5
AFG3 like matrix AAA peptidase subunit 2, isoform A

1

9

High-throughput

0.407

High

1472009

INO80
Chromatin-remodeling ATPase INO80

1

3

High-throughput

0.407

High

1475183

Q9VH84
Pinin, isoform A

1

6

High-throughput

0.407

High

1475195

Q9VKG8
Discs large 5, isoform A

1

2

High-throughput

0.407

High

1475214

Q9VT60
phospholipase A2

1

4

High-throughput

0.407

High

1475238

Q9VYE9
Pre-mRNA-splicing factor 38

1

9

High-throughput

0.407

High

1475240

Q9VYW5
LD23158p

1

1

High-throughput

0.407

High

1475241

YTDC1
YTH domain-containing protein 1

1

3

High-throughput

0.407

High

1475256

Q9W3R9
FI03239p

1

9

High-throughput

0.407

High

1475242

ETIF1
Eukaryotic translation initiation factor eIF1

2

0

High-throughput

0.310

High

684564

PSMD7
26S proteasome non-ATPase regulatory subunit 7

1

0

High-throughput

0.279

Low

1168975

CLIFF
Madf and zinc finger protein 1

1

0

High-throughput

0.279

Low

1237537

Q6NR30
RE38958p

1

0

High-throughput

0.279

Low

1266248

MEPCE
7SK snRNA methylphosphate capping enzyme bin3

1

0

High-throughput

0.279

Low

1267344

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

0

High-throughput

0.279

Low

1285815

Q86BS3
Chromator, isoform A

1

0

High-throughput

0.279

Low

1303235

Q8IMF0
Uncharacterized protein, isoform B

1

0

High-throughput

0.279

Low

1466181

SYF2
Pre-mRNA-splicing factor Syf2

1

0

High-throughput

0.279

Low

1466569

TOPRS
E3 ubiquitin-protein ligase Topors

1

0

High-throughput

0.279

Low

1467375

Q9VA69
procollagen-proline 4-dioxygenase

1

0

High-throughput

0.279

Low

1475194

Q9VK57
PIH1 domain-containing protein 1

1

0

High-throughput

0.279

Low

1475206

Q9VPQ4
Uncharacterized protein, isoform C

1

0

High-throughput

0.279

Low

1475213

Q9VRF3
LD38858p

1

0

High-throughput

0.279

Low

1475219

Q9VUR1
General transcription factor IIH subunit 4

1

0

High-throughput

0.279

Low

1475226

Q9VVL8
Tryptophan--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

1475245

ZER1
Protein zer-1 homolog

1

0

High-throughput

0.279

Low

1475251

VIR
Protein virilizer

1

0

High-throughput

0.279

Low

1475257

Q9W3Z4
GH18625p

1

0

High-throughput

0.279

Low

55164

A1Z951
MIP12871p

1

0

High-throughput

0.232

Low

1475267

Q9XZ11
Smr domain-containing protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025