Protein: PQBP1
Polyglutamine-binding protein 1 (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38) (Polyglutamine tract-binding protein 1)

Gene: PQBP1
Organism: Homo sapiens
Interactions: 83
UniProt ID: O60828

Gene Ontology (top 5):
GO:0000380 - alternative mRNA splicing, via spliceosome
GO:0002218 - activation of innate immune response
GO:0002230 - positive regulation of defense response to virus by host
GO:0003677 - DNA binding
GO:0003690 - double-stranded DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

241916

WBP11
WW domain-binding protein 11

7

0

Small-scale

0.719

High

241883

MARE1
Microtubule-associated protein RP/EB family member 1

3

0

High-throughput

0.646

High

241885

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

2

1

High-throughput

0.628

High

241903

LZTS2
Leucine zipper putative tumor suppressor 2

2

0

High-throughput

0.618

High

241845

ESR1
Estrogen receptor

3

0

Small-scale

0.613

High

241872

TXN4A
Thioredoxin-like protein 4A

3

0

Small-scale

0.612

High

241861

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

2

2

High-throughput

0.611

High

241878

RBM39
RNA-binding protein 39

2

0

High-throughput

0.585

High

241864

ATX1
Ataxin-1

2

0

Small-scale

0.575

High

241841

BRD4
Bromodomain-containing protein 4

2

0

High-throughput

0.559

High

241859

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.537

High

241867

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

2

High-throughput

0.536

High

241868

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

2

High-throughput

0.536

High

241857

PO3F2
POU domain, class 3, transcription factor 2

1

0

Small-scale

0.529

High

211772

TLX3
T-cell leukemia homeobox protein 3

1

0

High-throughput

0.518

High

241870

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.518

High

241918

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.518

High

241850

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.513

High

241851

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.513

High

241852

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

241854

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

241856

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.513

High

241875

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

241876

ANK3
Ankyrin-3

1

0

High-throughput

0.513

High

241881

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

0

High-throughput

0.513

High

241882

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.513

High

241901

RSRC1
Serine/Arginine-related protein 53

1

0

High-throughput

0.513

High

241907

GDF3
Growth/differentiation factor 3

1

0

High-throughput

0.513

High

241911

TFP11
Tuftelin-interacting protein 11

1

0

High-throughput

0.513

High

241912

SAE1
SUMO-activating enzyme subunit 1

1

0

High-throughput

0.513

High

241913

CSN7A
COP9 signalosome complex subunit 7a

1

0

High-throughput

0.513

High

241920

PAXB1
PAX3- and PAX7-binding protein 1

1

0

High-throughput

0.513

High

241863

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.505

High

241898

LNX1
E3 ubiquitin-protein ligase LNX

1

0

Small-scale

0.504

High

241862

HD
Huntingtin

1

0

High-throughput

0.493

High

230687

AQR
RNA helicase aquarius

1

0

High-throughput

0.486

High

241865

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

0

High-throughput

0.486

High

241902

MEP50
Methylosome protein WDR77

1

0

High-throughput

0.486

High

241896

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

1

High-throughput

0.481

High

120770

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.480

High

241849

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

241844

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

241847

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

241890

BCOR
BCL-6 corepressor

1

1

High-throughput

0.479

High

241897

NUP43
Nucleoporin Nup43

1

1

High-throughput

0.479

High

241917

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

1

High-throughput

0.479

High

241919

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

1

High-throughput

0.479

High

241887

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.460

High

241908

RBM22
Pre-mRNA-splicing factor RBM22

1

0

High-throughput

0.460

High

241842

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

241843

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

241846

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

241848

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

241858

ICAL
Calpastatin

1

0

High-throughput

0.458

High

241869

H4
Histone H4

1

0

High-throughput

0.458

High

241871

H31
Histone H3.1

1

0

High-throughput

0.458

High

241873

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

241879

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

241880

SF3A2
Splicing factor 3A subunit 2

1

0

High-throughput

0.458

High

241884

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

241889

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

241891

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

241892

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

241893

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

241894

STING
Stimulator of interferon genes protein

1

0

Small-scale

0.458

High

241895

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

241899

CELF1
CUGBP Elav-like family member 1

1

0

High-throughput

0.458

High

241900

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

0

High-throughput

0.458

High

241904

PCGF1
Polycomb group RING finger protein 1

1

0

High-throughput

0.458

High

241905

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

241909

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

241910

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

241914

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

241853

CLCB
Clathrin light chain B

1

0

High-throughput

0.438

High

241866

RAB8A
Ras-related protein Rab-8A

1

0

High-throughput

0.438

High

241888

RIF1
Telomere-associated protein RIF1

1

0

High-throughput

0.438

High

241877

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

241906

UBL5
Ubiquitin-like protein 5

1

0

Small-scale

0.426

High

241874

GOGA2
Golgin subfamily A member 2

2

0

High-throughput

0.337

High

241860

RECO
Recoverin

1

0

High-throughput

0.282

High

241915

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.282

High

241886

CE022
UPF0489 protein C5orf22

1

0

High-throughput

0.279

Low

241855

PSPC
Surfactant protein C

1

0

Small-scale

0.261

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024