Protein: FGFR2
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)

Gene: FGFR2
Organism: Homo sapiens
Interactions: 215
UniProt ID: P21802

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001525 - angiogenesis
GO:0001657 - ureteric bud development
GO:0001701 - in utero embryonic development
GO:0001837 - epithelial to mesenchymal transition

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

399132

FGF1
Fibroblast growth factor 1

13

20

Small-scale

0.981

High

447019

FGF2
Fibroblast growth factor 2

13

20

Small-scale

0.981

High

601112

FGF7
Fibroblast growth factor 7

8

20

Small-scale

0.967

High

601455

FGFR2
Fibroblast growth factor receptor 2

6

16

Small-scale

0.951

High

580923

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

4

20

Small-scale

0.922

High

601492

GRB2
Growth factor receptor-bound protein 2

4

20

Small-scale

0.912

High

601482

KS6A3
Ribosomal protein S6 kinase alpha-3

4

20

High-throughput

0.906

High

601456

FGFR3
Fibroblast growth factor receptor 3

3

17

Small-scale

0.876

High

181659

FGF10
Fibroblast growth factor 10

4

20

Small-scale

0.874

High

507854

FGFR1
Fibroblast growth factor receptor 1

3

17

High-throughput

0.871

High

601612

KDIS
Kinase D-interacting substrate of 220 kDa

3

20

High-throughput

0.861

High

601516

KS6A2
Ribosomal protein S6 kinase alpha-2

2

20

High-throughput

0.811

High

601466

PTN6
Tyrosine-protein phosphatase non-receptor type 6

2

20

Small-scale

0.793

High

601501

PTN11
Tyrosine-protein phosphatase non-receptor type 11

2

20

High-throughput

0.793

High

601517

KS6A1
Ribosomal protein S6 kinase alpha-1

2

20

High-throughput

0.789

High

601521

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

8

High-throughput

0.778

High

601463

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

20

Small-scale

0.754

High

601467

SHC1
SHC-transforming protein 1

1

20

Small-scale

0.747

High

513407

FGF3
Fibroblast growth factor 3

2

20

Small-scale

0.738

High

499376

FGF6
Fibroblast growth factor 6

2

20

Small-scale

0.727

High

601468

FGF9
Fibroblast growth factor 9

2

20

Small-scale

0.727

High

601487

FCGRN
IgG receptor FcRn large subunit p51

2

19

High-throughput

0.726

High

601568

LRIQ1
Leucine-rich repeat and IQ domain-containing protein 1

2

17

High-throughput

0.726

High

601500

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

20

High-throughput

0.698

High

601515

PTPRR
Receptor-type tyrosine-protein phosphatase R

1

20

High-throughput

0.698

High

601597

S10AE
Protein S100-A14

1

4

High-throughput

0.698

High

601458

KALM
Anosmin-1

1

18

Small-scale

0.692

High

601472

RYK
Tyrosine-protein kinase RYK

1

16

High-throughput

0.691

High

601496

CD83
CD83 antigen

1

1

High-throughput

0.691

High

237786

TSN3
Tetraspanin-3

3

8

High-throughput

0.667

High

601607

S53A1
Solute carrier family 53 member 1

3

2

High-throughput

0.667

High

522773

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.665

High

441808

FGF4
Fibroblast growth factor 4

1

20

Small-scale

0.647

High

601514

NECT1
Nectin-1

1

20

Small-scale

0.647

High

382306

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

16

High-throughput

0.646

High

601554

FRS2
Fibroblast growth factor receptor substrate 2

3

20

Small-scale

0.640

High

165398

SR140
U2 snRNP-associated SURP motif-containing protein

2

8

High-throughput

0.628

High

344791

TIMP1
Metalloproteinase inhibitor 1

2

3

High-throughput

0.628

High

555076

CD44
CD44 antigen

2

6

High-throughput

0.628

High

601471

SDC2
Syndecan-2

2

4

High-throughput

0.628

High

601502

GOGA3
Golgin subfamily A member 3

2

13

High-throughput

0.628

High

601510

UBE4A
Ubiquitin conjugation factor E4 A

2

6

High-throughput

0.628

High

601513

GAPD1
GTPase-activating protein and VPS9 domain-containing protein 1

2

20

High-throughput

0.628

High

601522

CC50B
Cell cycle control protein 50B

2

6

High-throughput

0.628

High

601533

F171B
Protein FAM171B

2

20

High-throughput

0.628

High

601542

CHERP
Calcium homeostasis endoplasmic reticulum protein

2

8

High-throughput

0.628

High

601545

SIGL1
SIGLEC family-like protein 1

2

1

High-throughput

0.628

High

601552

RAE1E
Retinoic acid early transcript 1E

2

20

High-throughput

0.628

High

601565

MRAP2
Melanocortin-2 receptor accessory protein 2

2

3

High-throughput

0.628

High

601576

PKP4
Plakophilin-4

2

20

High-throughput

0.628

High

601578

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

2

1

High-throughput

0.628

High

601588

BC11A
B-cell lymphoma/leukemia 11A

2

1

High-throughput

0.628

High

383605

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

Small-scale

0.621

High

601527

ATD3B
ATPase family AAA domain-containing protein 3B

2

13

High-throughput

0.618

High

129199

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

High-throughput

0.618

High

277002

STAM2
Signal transducing adapter molecule 2

1

20

High-throughput

0.618

High

412008

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.618

High

433573

LYN
Tyrosine-protein kinase Lyn

1

20

Small-scale

0.618

High

601465

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

601470

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.618

High

601474

STAT3
Signal transducer and activator of transcription 3

1

19

Small-scale

0.618

High

601477

STA5A
Signal transducer and activator of transcription 5A

1

19

Small-scale

0.618

High

601480

DYN2
Dynamin-2

1

12

High-throughput

0.618

High

601481

STA5B
Signal transducer and activator of transcription 5B

1

19

Small-scale

0.618

High

601484

EPHA4
Ephrin type-A receptor 4

1

20

Small-scale

0.618

High

601488

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

20

High-throughput

0.618

High

601499

DYST
Dystonin

1

18

High-throughput

0.618

High

601532

SCYL2
SCY1-like protein 2

1

20

High-throughput

0.618

High

601541

KLOTB
Beta-klotho

1

11

Small-scale

0.618

High

601574

ERBIN
Erbin

1

20

High-throughput

0.618

High

601589

TARA
TRIO and F-actin-binding protein

1

20

High-throughput

0.618

High

601605

ITSN2
Intersectin-2

1

20

High-throughput

0.618

High

601616

DYN3
Dynamin-3

1

13

High-throughput

0.618

High

601557

IP6K1
Inositol hexakisphosphate kinase 1

2

0

High-throughput

0.602

High

601586

CE295
Centrosomal protein of 295 kDa

2

0

High-throughput

0.602

High

601493

1433Z
14-3-3 protein zeta/delta

1

20

Small-scale

0.575

High

601528

IFFO2
Intermediate filament family orphan 2

2

2

High-throughput

0.574

High

601558

UBXN4
UBX domain-containing protein 4

2

4

High-throughput

0.574

High

601567

CC120
Coiled-coil domain-containing protein 120

2

1

High-throughput

0.574

High

601570

SNX22
Sorting nexin-22

2

1

High-throughput

0.574

High

601571

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

2

20

High-throughput

0.574

High

601620

SNX24
Sorting nexin-24

2

20

High-throughput

0.574

High

601535

MPRIP
Myosin phosphatase Rho-interacting protein

1

20

High-throughput

0.553

High

601561

STAM1
Signal transducing adapter molecule 1

1

20

High-throughput

0.553

High

171193

CTDSL
CTD small phosphatase-like protein

1

8

High-throughput

0.541

High

300661

GLCE
D-glucuronyl C5-epimerase

1

1

High-throughput

0.541

High

304916

DUS14
Dual specificity protein phosphatase 14

1

20

High-throughput

0.541

High

453065

HXC6
Homeobox protein Hox-C6

1

2

High-throughput

0.541

High

601473

PPM1A
Protein phosphatase 1A

1

9

High-throughput

0.541

High

601507

MTMR3
Myotubularin-related protein 3

1

20

High-throughput

0.541

High

601569

PDLI2
PDZ and LIM domain protein 2

1

15

High-throughput

0.541

High

601575

RSLAB
Ras-like protein family member 10B

1

20

High-throughput

0.541

High

601581

MTA3
Metastasis-associated protein MTA3

1

5

High-throughput

0.541

High

601583

BEX2
Protein BEX2

1

3

High-throughput

0.541

High

601585

RHBT2
Rho-related BTB domain-containing protein 2

1

20

High-throughput

0.541

High

601587

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

8

High-throughput

0.541

High

601593

BEX1
Protein BEX1

1

3

High-throughput

0.541

High

601608

ERRFI
ERBB receptor feedback inhibitor 1

1

11

High-throughput

0.541

High

601478

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

16

High-throughput

0.536

High

565996

INAR1
Interferon alpha/beta receptor 1

1

17

High-throughput

0.536

High

601459

IL32
Interleukin-32

1

1

High-throughput

0.536

High

601461

IL3RA
Interleukin-3 receptor subunit alpha

1

20

High-throughput

0.536

High

601469

SDC4
Syndecan-4

1

4

High-throughput

0.536

High

601491

ARF6
ADP-ribosylation factor 6

1

20

High-throughput

0.536

High

601546

RN149
E3 ubiquitin-protein ligase RNF149

1

10

High-throughput

0.536

High

601551

MARH1
E3 ubiquitin-protein ligase MARCHF1

1

3

High-throughput

0.536

High

601559

SL9A6
Sodium/hydrogen exchanger 6

1

2

High-throughput

0.536

High

601594

CRLF2
Cytokine receptor-like factor 2

1

15

High-throughput

0.536

High

601610

FBX2
F-box only protein 2

1

9

High-throughput

0.536

High

601613

CLC4A
C-type lectin domain family 4 member A

1

10

High-throughput

0.536

High

601615

EDAR
Tumor necrosis factor receptor superfamily member EDAR

1

9

High-throughput

0.536

High

159885

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

20

Small-scale

0.533

High

225918

FGF17
Fibroblast growth factor 17

1

20

Small-scale

0.527

High

517732

FGF5
Fibroblast growth factor 5

1

20

Small-scale

0.527

High

601485

FGF8
Fibroblast growth factor 8

1

20

Small-scale

0.527

High

377859

TFF1
Trefoil factor 1

1

0

High-throughput

0.518

High

601544

TM130
Transmembrane protein 130

1

0

High-throughput

0.513

High

601547

CS018
Uncharacterized protein C19orf18

1

0

High-throughput

0.513

High

394116

A4
Amyloid-beta precursor protein

1

12

High-throughput

0.501

High

601464

CCN2
CCN family member 2

1

1

Small-scale

0.501

High

601621

FBX7
F-box only protein 7

1

5

High-throughput

0.501

High

215106

LANC1
Glutathione S-transferase LANCL1

1

4

High-throughput

0.500

High

266909

SRS10
Serine/arginine-rich splicing factor 10

1

8

High-throughput

0.500

High

268399

BAF
Barrier-to-autointegration factor

1

8

High-throughput

0.500

High

523522

XRCC6
X-ray repair cross-complementing protein 6

1

2

High-throughput

0.500

High

578381

RCC1
Regulator of chromosome condensation

1

4

High-throughput

0.500

High

594674

MPRD
Cation-dependent mannose-6-phosphate receptor

1

3

High-throughput

0.500

High

601460

HMGB2
High mobility group protein B2

1

15

High-throughput

0.500

High

601462

CALX
Calnexin

1

20

High-throughput

0.500

High

601494

PRKDC
DNA-dependent protein kinase catalytic subunit

1

14

High-throughput

0.500

High

601495

TFAM
Transcription factor A, mitochondrial

1

10

High-throughput

0.500

High

601497

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

19

High-throughput

0.500

High

601503

LG3BP
Galectin-3-binding protein

1

10

High-throughput

0.500

High

601504

SSRP1
FACT complex subunit SSRP1

1

10

High-throughput

0.500

High

601505

SRSF9
Serine/arginine-rich splicing factor 9

1

12

High-throughput

0.500

High

601506

TRA2A
Transformer-2 protein homolog alpha

1

10

High-throughput

0.500

High

601508

DX39B
Spliceosome RNA helicase DDX39B

1

9

High-throughput

0.500

High

601518

SAFB1
Scaffold attachment factor B1

1

20

High-throughput

0.500

High

601520

CDC37
Hsp90 co-chaperone Cdc37

1

20

High-throughput

0.500

High

601526

UBR4
E3 ubiquitin-protein ligase UBR4

1

3

High-throughput

0.500

High

601550

ZSC18
Zinc finger and SCAN domain-containing protein 18

1

4

High-throughput

0.500

High

601572

RBM14
RNA-binding protein 14

1

20

High-throughput

0.500

High

601579

AIF1L
Allograft inflammatory factor 1-like

1

2

High-throughput

0.500

High

601580

NTPCR
Cancer-related nucleoside-triphosphatase

1

10

High-throughput

0.500

High

601584

PDIP3
Polymerase delta-interacting protein 3

1

6

High-throughput

0.500

High

601602

FANCI
Fanconi anemia group I protein

1

11

High-throughput

0.500

High

601603

ATD3A
ATPase family AAA domain-containing protein 3A

1

12

High-throughput

0.500

High

601611

MRT4
mRNA turnover protein 4 homolog

1

7

High-throughput

0.500

High

601622

SP16H
FACT complex subunit SPT16

1

4

High-throughput

0.500

High

601623

RBM8A
RNA-binding protein 8A

1

8

High-throughput

0.500

High

601619

PDIP2
Polymerase delta-interacting protein 2

1

0

High-throughput

0.479

High

120833

APBB1
Amyloid beta precursor protein binding family B member 1

1

5

High-throughput

0.479

High

514771

MPRI
Cation-independent mannose-6-phosphate receptor

1

8

High-throughput

0.479

High

280205

CBPD
Carboxypeptidase D

1

11

High-throughput

0.479

High

302898

HEXI1
Protein HEXIM1

1

4

High-throughput

0.479

High

315649

SC24B
Protein transport protein Sec24B

1

20

High-throughput

0.479

High

414437

PRGR
Progesterone receptor

1

6

Small-scale

0.479

High

443038

ITA5
Integrin alpha-5

1

7

Small-scale

0.479

High

525846

IFM1
Interferon-induced transmembrane protein 1

1

2

High-throughput

0.479

High

601457

CBL
E3 ubiquitin-protein ligase CBL

1

20

Small-scale

0.479

High

601475

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

11

High-throughput

0.479

High

601479

MMP14
Matrix metalloproteinase-14

1

4

Small-scale

0.479

High

601483

AGFG1
Arf-GAP domain and FG repeat-containing protein 1

1

20

High-throughput

0.479

High

601489

ABCE1
ATP-binding cassette sub-family E member 1

1

8

High-throughput

0.479

High

601498

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

13

High-throughput

0.479

High

601509

DSG2
Desmoglein-2

1

20

High-throughput

0.479

High

601511

FLOT2
Flotillin-2

1

17

High-throughput

0.479

High

601512

EPN4
Clathrin interactor 1

1

20

High-throughput

0.479

High

601519

TRIPB
Thyroid receptor-interacting protein 11

1

20

High-throughput

0.479

High

601523

GRDN
Girdin

1

17

High-throughput

0.479

High

601524

LARP7
La-related protein 7

1

20

High-throughput

0.479

High

601525

ZN326
DBIRD complex subunit ZNF326

1

3

High-throughput

0.479

High

601529

WAC2A
WASH complex subunit 2A

1

3

High-throughput

0.479

High

601530

STEA3
Metalloreductase STEAP3

1

4

High-throughput

0.479

High

601534

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

10

High-throughput

0.479

High

601536

GRIN3
G protein-regulated inducer of neurite outgrowth 3

1

14

High-throughput

0.479

High

601548

VANG1
Vang-like protein 1

1

13

High-throughput

0.479

High

601549

GOGA5
Golgin subfamily A member 5

1

12

High-throughput

0.479

High

601553

DLG5
Disks large homolog 5

1

20

High-throughput

0.479

High

601555

SMAP2
Stromal membrane-associated protein 2

1

20

High-throughput

0.479

High

601560

US6NL
USP6 N-terminal-like protein

1

20

High-throughput

0.479

High

601562

APBB2
Amyloid beta precursor protein binding family B member 2

1

5

High-throughput

0.479

High

601566

DDX27
Probable ATP-dependent RNA helicase DDX27

1

20

High-throughput

0.479

High

601573

MTMR9
Myotubularin-related protein 9

1

17

High-throughput

0.479

High

601582

RFIP5
Rab11 family-interacting protein 5

1

13

High-throughput

0.479

High

601590

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

9

High-throughput

0.479

High

601591

GCP60
Golgi resident protein GCP60

1

17

High-throughput

0.479

High

601592

WDR26
WD repeat-containing protein 26

1

16

High-throughput

0.479

High

601595

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

16

Small-scale

0.479

High

601596

Q9HCK3
KIAA1569 protein

1

3

High-throughput

0.479

High

601598

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

20

High-throughput

0.479

High

601599

JPH1
Junctophilin-1

1

10

High-throughput

0.479

High

601600

WDR6
tRNA

1

20

High-throughput

0.479

High

601604

GGA3
ADP-ribosylation factor-binding protein GGA3

1

20

High-throughput

0.479

High

601609

GGA2
ADP-ribosylation factor-binding protein GGA2

1

20

High-throughput

0.479

High

601614

SYNRG
Synergin gamma

1

1

High-throughput

0.479

High

601617

MTMR6
Myotubularin-related protein 6

1

17

High-throughput

0.479

High

601618

TPPC8
Trafficking protein particle complex subunit 8

1

3

High-throughput

0.479

High

601540

LAP4B
Lysosomal-associated transmembrane protein 4B

1

0

Small-scale

0.458

High

601476

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

14

High-throughput

0.457

High

601486

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

9

High-throughput

0.457

High

601490

COPZ1
Coatomer subunit zeta-1

1

6

High-throughput

0.457

High

601537

RIR2B
Ribonucleoside-diphosphate reductase subunit M2 B

1

3

High-throughput

0.457

High

601539

MON2
Protein MON2 homolog

1

8

High-throughput

0.457

High

313504

ZFYV9
Zinc finger FYVE domain-containing protein 9

1

20

High-throughput

0.437

High

601538

ZFY16
Zinc finger FYVE domain-containing protein 16

1

20

High-throughput

0.437

High

601543

M21D2
Nucleotidyltransferase MB21D2

1

10

High-throughput

0.437

High

601563

SEH1
Nucleoporin SEH1

1

10

High-throughput

0.437

High

601564

OTUB1
Ubiquitin thioesterase OTUB1

1

1

Small-scale

0.437

High

601577

CDCA3
Cell division cycle-associated protein 3

1

13

High-throughput

0.437

High

601606

F135A
Protein FAM135A

1

7

High-throughput

0.437

High

601531

CH074
Uncharacterized protein C8orf74

3

0

High-throughput

0.347

High

601601

ABHDA
Palmitoyl-protein thioesterase ABHD10, mitochondrial

1

0

High-throughput

0.261

Low

601556

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024