Protein: VPS53
Vacuolar protein sorting-associated protein 53 homolog

Gene: VPS53
Organism: Homo sapiens
Interactions: 94
UniProt ID: Q5VIR6

Gene Ontology (top 5):
GO:0000938 - GARP complex
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0006622 - protein targeting to lysosome
GO:0007041 - lysosomal transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1137638

VPS50
Syndetin

7

6

Small-scale

0.751

High

1137654

VPS54
Vacuolar protein sorting-associated protein 54

5

3

Small-scale

0.718

High

1121517

EIPR1
EARP and GARP complex-interacting protein 1

5

1

Small-scale

0.714

High

1137656

VPS51
Vacuolar protein sorting-associated protein 51 homolog

4

2

Small-scale

0.687

High

1137629

VPS52
Vacuolar protein sorting-associated protein 52 homolog

4

4

Small-scale

0.683

High

320334

SNP29
Synaptosomal-associated protein 29

3

0

High-throughput

0.638

High

726243

BASI
Basigin

3

0

High-throughput

0.638

High

849217

PSMD7
26S proteasome non-ATPase regulatory subunit 7

3

0

High-throughput

0.638

High

1137637

DTBP1
Dysbindin

3

0

High-throughput

0.638

High

1137631

EXOC6
Exocyst complex component 6

2

0

High-throughput

0.602

High

1137652

EXOC1
Exocyst complex component 1

2

0

High-throughput

0.602

High

212866

STX6
Syntaxin-6

2

1

Small-scale

0.584

High

172035

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.536

High

280885

KRT37
Keratin, type I cuticular Ha7

1

1

High-throughput

0.536

High

280995

KRT38
Keratin, type I cuticular Ha8

1

1

High-throughput

0.536

High

1131727

CE170
Centrosomal protein of 170 kDa

1

1

High-throughput

0.536

High

1137643

CML1
Chemerin-like receptor 1

1

1

High-throughput

0.536

High

242253

PRAF2
PRA1 family protein 2

1

0

High-throughput

0.513

High

801190

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

1137653

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.513

High

1137659

BL1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6

1

0

High-throughput

0.513

High

1137646

VP33B
Vacuolar protein sorting-associated protein 33B

1

0

High-throughput

0.493

High

1137639

EXOC2
Exocyst complex component 2

1

2

Small-scale

0.481

High

126136

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

1

High-throughput

0.479

High

181532

CLOCK
Circadian locomoter output cycles protein kaput

1

1

High-throughput

0.479

High

527514

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.479

High

591880

RAB4A
Ras-related protein Rab-4A

1

3

High-throughput

0.479

High

845531

RAB9A
Ras-related protein Rab-9A

1

1

High-throughput

0.479

High

895122

RAB2A
Ras-related protein Rab-2A

1

3

High-throughput

0.479

High

1137660

LAMP3
Lysosome-associated membrane glycoprotein 3

1

1

High-throughput

0.479

High

1137617

VPS53
Vacuolar protein sorting-associated protein 53 homolog

1

0

Small-scale

0.460

High

122202

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

High-throughput

0.458

High

178586

STX7
Syntaxin-7

1

0

High-throughput

0.458

High

204346

MS18B
Protein Mis18-beta

1

0

High-throughput

0.458

High

261673

VAMP4
Vesicle-associated membrane protein 4

1

0

Small-scale

0.458

High

279589

FLOT1
Flotillin-1

1

0

High-throughput

0.458

High

364307

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.458

High

409110

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.458

High

583495

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

875018

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

914123

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

1035467

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

1070119

RABE1
Rab GTPase-binding effector protein 1

1

0

High-throughput

0.458

High

1101104

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1118300

GRAP1
GRIP1-associated protein 1

1

0

High-throughput

0.458

High

1122575

CCD93
Coiled-coil domain-containing protein 93

1

0

High-throughput

0.458

High

1137620

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.458

High

1137621

PKN3
Serine/threonine-protein kinase N3

1

0

High-throughput

0.458

High

1137624

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

1137625

HAUS6
HAUS augmin-like complex subunit 6

1

0

High-throughput

0.458

High

1137632

GOGA5
Golgin subfamily A member 5

1

0

High-throughput

0.458

High

1137633

CCHCR
Coiled-coil alpha-helical rod protein 1

1

0

High-throughput

0.458

High

1137634

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

High-throughput

0.458

High

1137636

THA11
THAP domain-containing protein 11

1

0

High-throughput

0.458

High

1137644

NUF2
Kinetochore protein Nuf2

1

0

High-throughput

0.458

High

1137651

BRD7
Bromodomain-containing protein 7

1

0

High-throughput

0.458

High

1137655

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1137657

RABX5
Rab5 GDP/GTP exchange factor

1

0

High-throughput

0.458

High

1137635

PF21A
PHD finger protein 21A

1

1

High-throughput

0.437

High

1137645

UN93B
Protein unc-93 homolog B1

1

1

High-throughput

0.437

High

1137647

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

1137640

C170L
Cep170-like protein

1

1

High-throughput

0.407

High

50430

SYCE3
Synaptonemal complex central element protein 3

2

0

High-throughput

0.328

High

1116805

CCD40
Coiled-coil domain-containing protein 40

2

0

High-throughput

0.328

High

661292

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

740175

NUP62
Nuclear pore glycoprotein p62

1

0

High-throughput

0.279

Low

856393

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

1030952

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

0

High-throughput

0.279

Low

1102577

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1137626

TXND2
Thioredoxin domain-containing protein 2

1

0

High-throughput

0.279

Low

1137628

ENTD1
ENTH domain-containing protein 1

1

0

High-throughput

0.279

Low

1137642

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.279

Low

1137661

PSF2
DNA replication complex GINS protein PSF2

1

0

High-throughput

0.279

Low

81728

RBG10
Rab GTPase-activating protein 1-like, isoform 10

1

0

High-throughput

0.249

Low

132497

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

164393

TRI66
Tripartite motif-containing protein 66

1

0

High-throughput

0.249

Low

232225

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.249

Low

317456

YETS4
YEATS domain-containing protein 4

1

0

High-throughput

0.249

Low

471605

TFPT
TCF3 fusion partner

1

0

High-throughput

0.249

Low

898138

MAX
Protein max

1

0

High-throughput

0.249

Low

1050117

GIT2
ARF GTPase-activating protein GIT2

1

0

High-throughput

0.249

Low

1137618

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low

1137619

PHLB3
Pleckstrin homology-like domain family B member 3

1

0

High-throughput

0.249

Low

1137622

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1137623

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1137627

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

0

High-throughput

0.249

Low

1137630

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.249

Low

1137641

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

0

High-throughput

0.249

Low

1137648

NCK5L
Nck-associated protein 5-like

1

0

High-throughput

0.249

Low

1137649

TUFT1
Tuftelin

1

0

High-throughput

0.249

Low

1137650

HM20A
High mobility group protein 20A

1

0

High-throughput

0.249

Low

1137658

RCOR1
REST corepressor 1

1

0

High-throughput

0.249

Low

1091117

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024