Protein: MMP9
Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB) [Cleaved into: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9]

Gene: MMP9
Organism: Homo sapiens
Interactions: 63
UniProt ID: P14780

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0001934 - positive regulation of protein phosphorylation
GO:0004175 - endopeptidase activity
GO:0004222 - metalloendopeptidase activity
GO:0004252 - serine-type endopeptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

344786

TIMP1
Metalloproteinase inhibitor 1

4

20

Small-scale

0.899

High

540407

MMP9
Matrix metalloproteinase-9

3

7

Small-scale

0.853

High

362773

FINC
Fibronectin

2

12

High-throughput

0.811

High

530364

CSPG2
Versican core protein

1

12

Small-scale

0.724

High

540432

COL12
Collectin-12

1

20

High-throughput

0.691

High

540421

NGAL
Neutrophil gelatinase-associated lipocalin

4

3

Small-scale

0.676

High

540418

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

3

19

Small-scale

0.670

High

540409

TIMP2
Metalloproteinase inhibitor 2

1

20

Small-scale

0.647

High

540416

SFTPD
Pulmonary surfactant-associated protein D

1

15

Small-scale

0.647

High

358595

CO2A1
Collagen alpha-1(II) chain

2

20

High-throughput

0.628

High

358650

CO4A1

2

20

High-throughput

0.628

High

441053

CO4A2

2

20

High-throughput

0.628

High

517917

CO6A1

2

13

High-throughput

0.628

High

517985

CO6A2

2

20

High-throughput

0.628

High

540415

CO5A1

2

20

High-throughput

0.628

High

540424

COEA1
Collagen alpha-1(XIV) chain

2

17

High-throughput

0.628

High

540439

COCA1

2

17

High-throughput

0.628

High

486175

IL8
Interleukin-8

2

20

Small-scale

0.602

High

540420

CXCL6
C-X-C motif chemokine 6

2

20

Small-scale

0.602

High

540422

TF65
Transcription factor p65

2

2

Small-scale

0.584

High

540429

BGH3
Transforming growth factor-beta-induced protein ig-h3

1

2

Small-scale

0.578

High

540433

SCAR3
Scavenger receptor class A member 3

2

20

High-throughput

0.574

High

540430

MEP1A
Meprin A subunit alpha

1

5

Small-scale

0.536

High

540431

MEP1B
Meprin A subunit beta

1

5

Small-scale

0.536

High

198389

KLK10
Kallikrein-10

1

13

High-throughput

0.536

High

443027

ITA5
Integrin alpha-5

1

8

Small-scale

0.536

High

540423

GLGB
1,4-alpha-glucan-branching enzyme

1

1

High-throughput

0.536

High

540437

RHBL4
Rhomboid-related protein 4

1

3

High-throughput

0.536

High

540440

EGFL8
Epidermal growth factor-like protein 8

1

10

High-throughput

0.536

High

351244

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

4

Small-scale

0.501

High

364037

CXCL7
Platelet basic protein

1

20

Small-scale

0.501

High

394048

A4
Amyloid-beta precursor protein

1

6

Small-scale

0.501

High

436005

CO1A2
Collagen alpha-2(I) chain

1

20

Small-scale

0.501

High

540408

ELN
Elastin

1

20

Small-scale

0.501

High

540411

LEG3
Galectin-3

1

16

Small-scale

0.501

High

540414

CXCL2
C-X-C motif chemokine 2

1

20

Small-scale

0.501

High

540419

CXCL5
C-X-C motif chemokine 5

1

20

Small-scale

0.501

High

540435

SCUB3
Signal peptide, CUB and EGF-like domain-containing protein 3

1

15

Small-scale

0.501

High

540443

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

3

High-throughput

0.489

High

486071

SRGN
Serglycin

1

0

Small-scale

0.480

High

121099

LEG8
Galectin-8

1

16

Small-scale

0.479

High

345302

FOS
Protein c-Fos

1

7

Small-scale

0.479

High

431169

CATB
Cathepsin B

1

2

Small-scale

0.479

High

434613

TSP1
Thrombospondin-1

1

8

Small-scale

0.479

High

500706

CLUS
Clusterin

1

3

Small-scale

0.479

High

540413

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

3

Small-scale

0.479

High

540417

TSP2
Thrombospondin-2

1

7

Small-scale

0.479

High

540425

EP300
Histone acetyltransferase p300

1

4

Small-scale

0.479

High

540434

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

3

Small-scale

0.479

High

540438

CBP
CREB-binding protein

1

4

Small-scale

0.479

High

540442

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

2

High-throughput

0.479

High

500982

IRF1
Interferon regulatory factor 1

1

0

Small-scale

0.458

High

540412

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

540426

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

0

Small-scale

0.458

High

540428

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

439057

ELNE
Neutrophil elastase

1

12

Small-scale

0.457

High

403761

ITB1
Integrin beta-1

1

12

Small-scale

0.445

High

434918

SP1
Transcription factor Sp1

1

1

Small-scale

0.437

High

540410

JUND
Transcription factor JunD

1

4

Small-scale

0.437

High

540427

SKP2
S-phase kinase-associated protein 2

1

1

Small-scale

0.437

High

540436

FBXW8
F-box/WD repeat-containing protein 8

1

3

High-throughput

0.437

High

540441

CP343
Cytochrome P450 3A43

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024