Protein: PSMD8
26S proteasome non-ATPase regulatory subunit 8 (26S proteasome regulatory subunit RPN12) (26S proteasome regulatory subunit S14) (p31)

Gene: PSMD8
Organism: Homo sapiens
Interactions: 132
UniProt ID: P48556

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005838 - proteasome regulatory particle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

198571

PSMD3
26S proteasome non-ATPase regulatory subunit 3

6

2

Small-scale

0.946

High

819781

PSMD7
26S proteasome non-ATPase regulatory subunit 7

4

3

High-throughput

0.895

High

121962

PSD12
26S proteasome non-ATPase regulatory subunit 12

2

2

High-throughput

0.811

High

819857

PSD13
26S proteasome non-ATPase regulatory subunit 13

2

3

High-throughput

0.802

High

819860

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

8

2

Small-scale

0.747

High

130792

PSDE
26S proteasome non-ATPase regulatory subunit 14

7

5

Small-scale

0.740

High

819775

PSMD8
26S proteasome non-ATPase regulatory subunit 8

1

1

High-throughput

0.724

High

819785

PSMD4
26S proteasome non-ATPase regulatory subunit 4

5

2

Small-scale

0.719

High

798610

PRS6B
26S proteasome regulatory subunit 6B

4

7

Small-scale

0.694

High

819806

ADRM1
Proteasomal ubiquitin receptor ADRM1

4

1

High-throughput

0.694

High

819788

PRS4
26S proteasome regulatory subunit 4

4

7

Small-scale

0.686

High

656097

PSB9
Proteasome subunit beta type-9

3

6

High-throughput

0.667

High

819811

CCD92
Coiled-coil domain-containing protein 92

4

0

High-throughput

0.667

High

819804

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

3

High-throughput

0.665

High

572891

PRS6A
26S proteasome regulatory subunit 6A

3

6

Small-scale

0.656

High

819789

PRS8
26S proteasome regulatory subunit 8

3

7

Small-scale

0.656

High

730212

PRS7
26S proteasome regulatory subunit 7

3

5

Small-scale

0.640

High

819782

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

3

1

Small-scale

0.640

High

819794

UBE3A
Ubiquitin-protein ligase E3A

3

1

Small-scale

0.640

High

150903

DVL2
Segment polarity protein dishevelled homolog DVL-2

3

0

High-throughput

0.638

High

819807

PSMD5
26S proteasome non-ATPase regulatory subunit 5

3

0

Small-scale

0.634

High

276154

PSD10
26S proteasome non-ATPase regulatory subunit 10

2

1

High-throughput

0.628

High

819777

PSB3
Proteasome subunit beta type-3

2

9

High-throughput

0.628

High

819828

UBCP1
Ubiquitin-like domain-containing CTD phosphatase 1

2

1

Small-scale

0.611

High

819836

CC74B
Coiled-coil domain-containing protein 74B

3

1

High-throughput

0.609

High

819840

PAAF1
Proteasomal ATPase-associated factor 1

2

1

Small-scale

0.601

High

475475

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

4

High-throughput

0.595

High

226817

PRKN
E3 ubiquitin-protein ligase parkin

2

3

Small-scale

0.584

High

570498

PTN2
Tyrosine-protein phosphatase non-receptor type 2

2

1

High-throughput

0.584

High

819792

PRS10
26S proteasome regulatory subunit 10B

2

7

Small-scale

0.584

High

670676

PRDX6
Peroxiredoxin-6

2

0

High-throughput

0.580

High

819829

SHC3
SHC-transforming protein 3

2

0

High-throughput

0.580

High

496544

TAU
Microtubule-associated protein tau

2

1

High-throughput

0.571

High

819786

SEM1
26S proteasome complex subunit SEM1

2

0

Small-scale

0.559

High

122160

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

2

High-throughput

0.536

High

819799

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

7

High-throughput

0.536

High

819816

ECM29
Proteasome adapter and scaffold protein ECM29

1

1

High-throughput

0.536

High

819830

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.536

High

819796

TP53B
TP53-binding protein 1

1

0

High-throughput

0.529

High

270383

KS6A5
Ribosomal protein S6 kinase alpha-5

1

0

High-throughput

0.513

High

506545

BCR
Breakpoint cluster region protein

1

0

High-throughput

0.513

High

528757

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

687043

FOXN2
Forkhead box protein N2

1

0

High-throughput

0.513

High

819823

ASXL1
Polycomb group protein ASXL1

1

0

High-throughput

0.513

High

819825

BBS5
Bardet-Biedl syndrome 5 protein

1

0

High-throughput

0.513

High

819839

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.513

High

171371

SMAD9
Mothers against decapentaplegic homolog 9

1

1

High-throughput

0.508

High

819779

GSK3A
Glycogen synthase kinase-3 alpha

1

3

High-throughput

0.508

High

819780

GSK3B
Glycogen synthase kinase-3 beta

1

3

High-throughput

0.508

High

819805

SMAD2
Mothers against decapentaplegic homolog 2

1

1

High-throughput

0.508

High

316820

KLF8
Krueppel-like factor 8

1

1

High-throughput

0.500

High

819841

KLF16
Krueppel-like factor 16

1

1

High-throughput

0.500

High

146608

SOCS2
Suppressor of cytokine signaling 2

1

0

High-throughput

0.493

High

725111

MYH10
Myosin-10

1

0

High-throughput

0.493

High

819826

ARRD4
Arrestin domain-containing protein 4

1

1

High-throughput

0.489

High

819827

ARRD2
Arrestin domain-containing protein 2

1

1

High-throughput

0.489

High

819831

CC74A
Coiled-coil domain-containing protein 74A

1

1

High-throughput

0.489

High

568189

TAL1
T-cell acute lymphocytic leukemia protein 1

1

0

High-throughput

0.479

High

397837

ISG15
Ubiquitin-like protein ISG15

1

4

Small-scale

0.479

High

617473

CRCM
Colorectal mutant cancer protein

1

1

High-throughput

0.479

High

625219

CDK2
Cyclin-dependent kinase 2

1

2

High-throughput

0.479

High

637645

PSA2
Proteasome subunit alpha type-2

1

5

Small-scale

0.479

High

819783

RD23A
UV excision repair protein RAD23 homolog A

1

7

Small-scale

0.479

High

819784

RD23B
UV excision repair protein RAD23 homolog B

1

9

High-throughput

0.479

High

819808

MK06
Mitogen-activated protein kinase 6

1

1

High-throughput

0.479

High

819809

LARP7
La-related protein 7

1

1

High-throughput

0.479

High

819813

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.479

High

819815

DDI2
Protein DDI1 homolog 2

1

8

High-throughput

0.479

High

819846

MYO10
Unconventional myosin-X

1

1

Small-scale

0.479

High

819847

UBQL4
Ubiquilin-4

1

9

Small-scale

0.479

High

819852

UBQL2
Ubiquilin-2

1

5

High-throughput

0.479

High

819856

UBQL1
Ubiquilin-1

1

6

High-throughput

0.479

High

819858

RNF11
RING finger protein 11

1

1

Small-scale

0.479

High

819859

TRAF6
TNF receptor-associated factor 6

1

1

High-throughput

0.479

High

265124

MAF
Transcription factor Maf

1

0

Small-scale

0.458

High

294513

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

298269

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

299332

UBXN7
UBX domain-containing protein 7

1

0

High-throughput

0.458

High

324273

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

325657

LATS1
Serine/threonine-protein kinase LATS1

1

0

High-throughput

0.458

High

552196

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

590709

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

650635

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

684506

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

718453

NOS2
Nitric oxide synthase, inducible

1

0

High-throughput

0.458

High

719937

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

779001

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

819787

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

819790

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

819791

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

819793

H31
Histone H3.1

1

0

High-throughput

0.458

High

819795

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

819797

TRI26
Tripartite motif-containing protein 26

1

0

Small-scale

0.458

High

819798

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

819800

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

Small-scale

0.458

High

819801

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

819810

MIDN
Midnolin

1

0

High-throughput

0.458

High

819817

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

819818

DESI1
Desumoylating isopeptidase 1

1

0

Small-scale

0.458

High

819821

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

819824

RPTOR
Regulatory-associated protein of mTOR

1

0

High-throughput

0.458

High

819834

RITA1
RBPJ-interacting and tubulin-associated protein 1

1

0

Small-scale

0.458

High

819835

SNX27
Sorting nexin-27

1

0

High-throughput

0.458

High

819838

PFD5
Prefoldin subunit 5

1

0

Small-scale

0.458

High

819843

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

0

Small-scale

0.458

High

819848

DJC11
DnaJ homolog subfamily C member 11

1

0

High-throughput

0.458

High

819849

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.458

High

819850

GRHPR
Glyoxylate reductase/hydroxypyruvate reductase

1

0

High-throughput

0.458

High

819851

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

819853

APC4
Anaphase-promoting complex subunit 4

1

0

Small-scale

0.458

High

819855

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

819778

PSB2
Proteasome subunit beta type-2

1

7

Small-scale

0.445

High

819820

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

819832

RN185
E3 ubiquitin-protein ligase RNF185

1

2

Small-scale

0.437

High

401622

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

819812

TMM31
Transmembrane protein 31

1

0

High-throughput

0.279

Low

819842

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low

819845

SG196
Protein O-mannose kinase

1

0

High-throughput

0.279

Low

819854

INTU
Protein inturned

1

0

High-throughput

0.279

Low

819776

MTR1B
Melatonin receptor type 1B

1

0

High-throughput

0.265

Low

793707

GLP1R
Glucagon-like peptide 1 receptor

1

0

Small-scale

0.251

Low

384468

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

660836

PTPRM
Receptor-type tyrosine-protein phosphatase mu

1

0

High-throughput

0.249

Low

819802

PTC1
Protein patched homolog 1

1

0

Small-scale

0.249

Low

819803

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

819819

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

819822

GOLI
E3 ubiquitin-protein ligase RNF130

1

0

High-throughput

0.249

Low

819833

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

819837

RN157
E3 ubiquitin ligase RNF157

1

0

Small-scale

0.249

Low

819844

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

819814

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024