Protein: NCF1
Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox)

Gene: NCF1
Organism: Homo sapiens
Interactions: 106
UniProt ID: P14598

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006612 - protein targeting to membrane
GO:0006801 - superoxide metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

537593

NCF2
Neutrophil cytosol factor 2

16

20

Small-scale

0.986

High

537631

KPCZ
Protein kinase C zeta type

4

12

Small-scale

0.899

High

537649

NCF4
Neutrophil cytosol factor 4

4

19

Small-scale

0.894

High

528147

CY24A
Cytochrome b-245 light chain

5

3

Small-scale

0.720

High

537668

TRAF4
TNF receptor-associated factor 4

5

5

Small-scale

0.714

High

537603

AKT1
RAC-alpha serine/threonine-protein kinase

1

10

Small-scale

0.692

High

537666

SH3G1
Endophilin-A2

1

20

High-throughput

0.691

High

537660

ABI1
Abl interactor 1

1

20

Small-scale

0.683

High

537607

PA24A
Cytosolic phospholipase A2

3

2

Small-scale

0.670

High

537646

FAK2
Protein-tyrosine kinase 2-beta

1

20

Small-scale

0.665

High

537595

FGFR3
Fibroblast growth factor receptor 3

1

20

High-throughput

0.665

High

408545

KPCB
Protein kinase C beta type

3

11

Small-scale

0.651

High

537638

PAK1
Serine/threonine-protein kinase PAK 1

3

20

Small-scale

0.651

High

537589

NCF1
Neutrophil cytosol factor 1

1

18

Small-scale

0.647

High

537617

ACTB
Actin, cytoplasmic 1

2

10

Small-scale

0.629

High

537657

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

20

High-throughput

0.621

High

537658

NOXA1
NADPH oxidase activator 1

1

4

Small-scale

0.621

High

537619

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.618

High

537667

SH3G3
Endophilin-A3

1

20

High-throughput

0.618

High

537591

KPCA
Protein kinase C alpha type

2

11

Small-scale

0.602

High

537632

KPCD
Protein kinase C delta type

2

13

Small-scale

0.602

High

537630

TF65
Transcription factor p65

1

1

Small-scale

0.598

High

537672

IRAK4
Interleukin-1 receptor-associated kinase 4

1

0

Small-scale

0.586

High

68112

NCF1C
Putative neutrophil cytosol factor 1C

1

17

High-throughput

0.575

High

111375

J3KT38
Growth factor receptor bound protein 2

1

20

High-throughput

0.575

High

537634

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

2

12

Small-scale

0.571

High

537600

MOES
Moesin

1

8

Small-scale

0.561

High

537669

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

17

High-throughput

0.541

High

526485

GP1BB
Platelet glycoprotein Ib beta chain

1

0

Small-scale

0.537

High

537623

ADAM8
Disintegrin and metalloproteinase domain-containing protein 8

1

20

Small-scale

0.536

High

378625

KITH
Thymidine kinase, cytosolic

1

1

High-throughput

0.536

High

443297

VIME
Vimentin

1

10

High-throughput

0.536

High

531018

EF2
Elongation factor 2

1

2

High-throughput

0.536

High

537594

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

2

High-throughput

0.536

High

537599

EF1B
Elongation factor 1-beta

1

1

High-throughput

0.536

High

537601

1433T
14-3-3 protein theta

1

20

High-throughput

0.536

High

537612

COPB
Coatomer subunit beta

1

7

High-throughput

0.536

High

537613

COPA
Coatomer subunit alpha

1

2

High-throughput

0.536

High

537614

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

4

High-throughput

0.536

High

537615

SYMC
Methionine--tRNA ligase, cytoplasmic

1

4

High-throughput

0.536

High

537633

PRDX1
Peroxiredoxin-1

1

1

High-throughput

0.536

High

537635

LG3BP
Galectin-3-binding protein

1

6

High-throughput

0.536

High

537639

PRDX4
Peroxiredoxin-4

1

1

High-throughput

0.536

High

537651

RBBP7
Histone-binding protein RBBP7

1

2

High-throughput

0.536

High

537663

HS105
Heat shock protein 105 kDa

1

10

High-throughput

0.536

High

537673

RCC2
Protein RCC2

1

1

High-throughput

0.536

High

413817

GELS
Gelsolin

1

3

High-throughput

0.515

High

537605

HD
Huntingtin

1

3

High-throughput

0.515

High

537590

CBR1
Carbonyl reductase [NADPH] 1

1

0

High-throughput

0.513

High

537597

RIR1
Ribonucleoside-diphosphate reductase large subunit

1

0

High-throughput

0.513

High

537604

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.513

High

537609

COPD
Coatomer subunit delta

1

0

High-throughput

0.513

High

537610

FAS
Fatty acid synthase

1

0

High-throughput

0.513

High

537621

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

0

High-throughput

0.513

High

537636

NSUN2
RNA cytosine C(5)-methyltransferase NSUN2

1

0

High-throughput

0.513

High

537640

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.513

High

537643

NAR3
Ecto-ADP-ribosyltransferase 3

1

0

High-throughput

0.513

High

537656

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.513

High

537665

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.513

High

537606

MK09
Mitogen-activated protein kinase 9

1

8

Small-scale

0.501

High

537608

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

8

Small-scale

0.501

High

537616

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

Small-scale

0.501

High

537624

PRKDC
DNA-dependent protein kinase catalytic subunit

1

3

Small-scale

0.501

High

537625

PKD1
Polycystin-1

1

4

Small-scale

0.501

High

537641

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

20

Small-scale

0.501

High

537642

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

1

20

Small-scale

0.501

High

537659

SYTL1
Synaptotagmin-like protein 1

1

3

Small-scale

0.501

High

537664

PASK
PAS domain-containing serine/threonine-protein kinase

1

8

Small-scale

0.501

High

537670

ADA19
Disintegrin and metalloproteinase domain-containing protein 19

1

20

Small-scale

0.501

High

503358

HSP7C
Heat shock cognate 71 kDa protein

1

6

High-throughput

0.500

High

537602

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.493

High

537629

ODO1
2-oxoglutarate dehydrogenase complex component E1

1

2

High-throughput

0.489

High

537652

H2A2C
Histone H2A type 2-C

1

5

High-throughput

0.489

High

537654

NOM1
Nucleolar MIF4G domain-containing protein 1

1

2

High-throughput

0.489

High

537661

RHBL4
Rhomboid-related protein 4

1

3

High-throughput

0.489

High

203578

MGA
Maltase-glucoamylase

1

1

Small-scale

0.481

High

486991

LYAG
Lysosomal alpha-glucosidase

1

1

Small-scale

0.481

High

537622

CSK2B
Casein kinase II subunit beta

1

3

Small-scale

0.481

High

537626

MYPC1
Myosin-binding protein C, slow-type

1

7

Small-scale

0.481

High

537627

SRSF2
Serine/arginine-rich splicing factor 2

1

11

Small-scale

0.481

High

537648

MYPC3
Myosin-binding protein C, cardiac-type

1

4

Small-scale

0.481

High

414149

RB
Retinoblastoma-associated protein

1

0

Small-scale

0.480

High

152245

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

20

Small-scale

0.479

High

200159

TGFI1
Transforming growth factor beta-1-induced transcript 1 protein

1

12

Small-scale

0.479

High

389773

CY24B
Cytochrome b-245 heavy chain

1

1

Small-scale

0.479

High

391318

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

1

Small-scale

0.479

High

537592

SYN1
Synapsin-1

1

20

Small-scale

0.479

High

537598

IL4RA
Interleukin-4 receptor subunit alpha

1

13

Small-scale

0.479

High

537618

ACTA
Actin, aortic smooth muscle

1

10

Small-scale

0.479

High

537620

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

1

Small-scale

0.479

High

537628

TAGL
Transgelin

1

7

Small-scale

0.479

High

537644

KEAP1
Kelch-like ECH-associated protein 1

1

4

Small-scale

0.479

High

537645

SRC8
Src substrate cortactin

1

19

Small-scale

0.479

High

537647

NF2L1
Endoplasmic reticulum membrane sensor NFE2L1

1

2

Small-scale

0.479

High

537650

NF2L2
Nuclear factor erythroid 2-related factor 2

1

3

Small-scale

0.479

High

537662

WASF1
Actin-binding protein WASF1

1

20

Small-scale

0.479

High

537671

GPVI
Platelet glycoprotein VI

1

3

Small-scale

0.479

High

267116

GEMI
Geminin

1

0

Small-scale

0.460

High

537655

Q6NSK7
RIN3 protein

1

20

High-throughput

0.457

High

437854

HS90B
Heat shock protein HSP 90-beta

1

1

High-throughput

0.445

High

537653

Q32Q12
Nucleoside diphosphate kinase

1

0

High-throughput

0.426

High

537611

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.373

High

158734

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.279

Low

537596

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

0

High-throughput

0.279

Low

537637

SF3A3
Splicing factor 3A subunit 3

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024