Protein: NH2L1
NHP2-like protein 1 (High mobility group-like nuclear protein 2 homolog 1) (OTK27) (SNU13 homolog) (hSNU13) (U4/U6.U5 small nuclear ribonucleoprotein SNU13) (U4/U6.U5 tri-snRNP 15.5 kDa protein) [Cleaved into: NHP2-like protein 1, N-terminally processed]

Gene: NH2L1, SNU13
Organism: Homo sapiens
Interactions: 163
UniProt ID: P55769

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0000470 - maturation of LSU-rRNA
GO:0000492 - box C/D snoRNP assembly
GO:0001651 - dense fibrillar component
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

196981

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

4

10

Small-scale

0.905

High

603411

FBRL
rRNA 2'-O-methyltransferase fibrillarin

4

2

High-throughput

0.887

High

878378

NUFP1
FMR1-interacting protein NUFIP1

4

1

Small-scale

0.882

High

133400

NOP56
Nucleolar protein 56

4

9

Small-scale

0.881

High

202399

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

3

0

Small-scale

0.819

High

878385

NOP58
Nucleolar protein 58

2

9

High-throughput

0.802

High

878348

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

2

9

Small-scale

0.757

High

215330

U3IP2
U3 small nucleolar RNA-interacting protein 2

1

11

High-throughput

0.691

High

878382

SRPK3
SRSF protein kinase 3

2

5

High-throughput

0.628

High

878287

NH2L1
NHP2-like protein 1

1

4

Small-scale

0.621

High

267971

EED
Polycomb protein EED

1

14

High-throughput

0.618

High

806773

RS9
Small ribosomal subunit protein uS4

1

4

High-throughput

0.618

High

878288

WDR5
WD repeat-containing protein 5

1

8

High-throughput

0.618

High

878371

DCA13
DDB1- and CUL4-associated factor 13

1

8

Small-scale

0.618

High

878381

FZR1
Fizzy-related protein homolog

1

10

High-throughput

0.618

High

878309

RBM39
RNA-binding protein 39

2

3

High-throughput

0.611

High

878313

SUZ12
Polycomb protein SUZ12

2

1

High-throughput

0.601

High

346340

MYC
Myc proto-oncogene protein

2

6

High-throughput

0.584

High

779102

CCNF
Cyclin-F

2

1

High-throughput

0.584

High

878319

EZH2
Histone-lysine N-methyltransferase EZH2

2

4

High-throughput

0.584

High

878333

MEPCE
7SK snRNA methylphosphate capping enzyme

2

1

High-throughput

0.584

High

878375

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

2

2

Small-scale

0.584

High

878322

SMN
Survival motor neuron protein

2

0

High-throughput

0.580

High

717600

BMI1
Polycomb complex protein BMI-1

2

7

High-throughput

0.571

High

878317

ZNHI3
Zinc finger HIT domain-containing protein 3

2

0

Small-scale

0.559

High

279008

RAD17
Cell cycle checkpoint protein RAD17

1

2

Small-scale

0.552

High

581580

VCAM1
Vascular cell adhesion protein 1

2

1

High-throughput

0.549

High

790964

CDN2C
Cyclin-dependent kinase 4 inhibitor C

1

1

High-throughput

0.541

High

878298

RBM10
RNA-binding protein 10

1

2

High-throughput

0.541

High

878308

DPOA2
DNA polymerase alpha subunit B

1

2

High-throughput

0.541

High

403135

LA
Lupus La protein

1

6

High-throughput

0.536

High

446555

SNRPA
U1 small nuclear ribonucleoprotein A

1

2

High-throughput

0.536

High

538880

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

3

High-throughput

0.536

High

595163

LMNB1
Lamin-B1

1

2

High-throughput

0.536

High

624832

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

High-throughput

0.536

High

739044

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.536

High

878290

RUXF
Small nuclear ribonucleoprotein F

1

1

High-throughput

0.536

High

878291

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

5

High-throughput

0.536

High

878292

LSM6
U6 snRNA-associated Sm-like protein LSm6

1

1

High-throughput

0.536

High

878293

SMD2
Small nuclear ribonucleoprotein Sm D2

1

1

High-throughput

0.536

High

878297

RSMN
Small nuclear ribonucleoprotein-associated protein N

1

3

High-throughput

0.536

High

878312

SART3
Squamous cell carcinoma antigen recognized by T-cells 3

1

2

High-throughput

0.536

High

878321

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

2

High-throughput

0.536

High

878336

ZCH18
Zinc finger CCCH domain-containing protein 18

1

4

High-throughput

0.536

High

878337

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

4

High-throughput

0.536

High

878358

RBM42
RNA-binding protein 42

1

3

High-throughput

0.536

High

878369

STK36
Serine/threonine-protein kinase 36

1

3

High-throughput

0.536

High

878379

LSM7
U6 snRNA-associated Sm-like protein LSm7

1

4

High-throughput

0.536

High

878388

LSM5
U6 snRNA-associated Sm-like protein LSm5

1

2

High-throughput

0.536

High

523631

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.518

High

878302

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.518

High

878356

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

3

High-throughput

0.515

High

448585

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

452700

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

508420

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

878294

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.513

High

878318

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

878357

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.513

High

878306

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.508

High

878320

HSPB2
Heat shock protein beta-2

1

1

High-throughput

0.508

High

878360

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

3

High-throughput

0.494

High

362976

FINC
Fibronectin

1

2

High-throughput

0.489

High

878301

CALD1
Caldesmon

1

4

High-throughput

0.489

High

203509

PPIH
Peptidyl-prolyl cis-trans isomerase H

1

2

Small-scale

0.481

High

122595

MEN1
Menin

1

2

High-throughput

0.479

High

125286

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

12

High-throughput

0.479

High

160464

AURKA
Aurora kinase A

1

3

High-throughput

0.479

High

182635

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.479

High

209808

PRC1
Protein regulator of cytokinesis 1

1

2

High-throughput

0.479

High

226988

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

233315

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

244182

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.479

High

278007

PIAS1
E3 SUMO-protein ligase PIAS1

1

1

High-throughput

0.479

High

303052

HEXI1
Protein HEXIM1

1

1

High-throughput

0.479

High

373948

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

379171

MYCN
N-myc proto-oncogene protein

1

6

High-throughput

0.479

High

441975

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

3

High-throughput

0.479

High

505593

EPB41
Protein 4.1

1

2

High-throughput

0.479

High

552351

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

569470

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

590748

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

625272

CDK2
Cyclin-dependent kinase 2

1

4

High-throughput

0.479

High

650794

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

720086

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

823761

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

832271

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

841592

CDK9
Cyclin-dependent kinase 9

1

4

High-throughput

0.479

High

849968

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

5

High-throughput

0.479

High

874731

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

877657

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.479

High

878289

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

878295

H4
Histone H4

1

2

High-throughput

0.479

High

878296

RBX1
E3 ubiquitin-protein ligase RBX1

1

1

High-throughput

0.479

High

878299

VIGLN
Vigilin

1

3

High-throughput

0.479

High

878300

KIF23
Kinesin-like protein KIF23

1

2

High-throughput

0.479

High

878303

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

5

High-throughput

0.479

High

878304

NFX1
Transcriptional repressor NF-X1

1

1

High-throughput

0.479

High

878305

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

High-throughput

0.479

High

878311

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

5

High-throughput

0.479

High

878314

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.479

High

878315

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

878316

OASL
2'-5'-oligoadenylate synthase-like protein

1

3

High-throughput

0.479

High

878323

IF16
Gamma-interferon-inducible protein 16

1

5

High-throughput

0.479

High

878324

LARP7
La-related protein 7

1

8

High-throughput

0.479

High

878326

RC3H1
Roquin-1

1

4

High-throughput

0.479

High

878328

FTM
Protein fantom

1

4

High-throughput

0.479

High

878329

IFIX
Pyrin and HIN domain-containing protein 1

1

5

High-throughput

0.479

High

878331

ASXL2
Putative Polycomb group protein ASXL2

1

1

High-throughput

0.479

High

878334

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

878335

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

4

Small-scale

0.479

High

878338

ASXL1
Polycomb group protein ASXL1

1

1

High-throughput

0.479

High

878339

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.479

High

878342

NIN
Ninein

1

2

High-throughput

0.479

High

878344

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

3

High-throughput

0.479

High

878345

SIR6
NAD-dependent protein deacylase sirtuin-6

1

2

High-throughput

0.479

High

878347

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

878349

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

878350

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

878351

FGF11
Fibroblast growth factor 11

1

1

High-throughput

0.479

High

878353

MBD6
Methyl-CpG-binding domain protein 6

1

2

High-throughput

0.479

High

878355

RING2
E3 ubiquitin-protein ligase RING2

1

7

High-throughput

0.479

High

878361

CHM4B
Charged multivesicular body protein 4b

1

4

High-throughput

0.479

High

878363

ECT2
Protein ECT2

1

2

High-throughput

0.479

High

878364

LN28A
Protein lin-28 homolog A

1

8

High-throughput

0.479

High

878365

RC3H2
Roquin-2

1

5

High-throughput

0.479

High

878366

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

12

High-throughput

0.479

High

878368

ANLN
Anillin

1

1

High-throughput

0.479

High

878373

PIHD1
PIH1 domain-containing protein 1

1

3

High-throughput

0.479

High

878374

MBD5
Methyl-CpG-binding domain protein 5

1

1

High-throughput

0.479

High

878377

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

878383

CE164
Centrosomal protein of 164 kDa

1

3

High-throughput

0.479

High

878384

RUVB1
RuvB-like 1

1

3

Small-scale

0.479

High

878386

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

3

Small-scale

0.479

High

878387

TRAF6
TNF receptor-associated factor 6

1

5

High-throughput

0.479

High

878389

MAFB
Transcription factor MafB

1

2

High-throughput

0.479

High

878325

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.460

High

742166

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

878343

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

0

Small-scale

0.458

High

878370

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

878332

RHOU
Rho-related GTP-binding protein RhoU

1

1

High-throughput

0.457

High

496658

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.445

High

878310

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

2

High-throughput

0.445

High

878346

POC5
Centrosomal protein POC5

1

1

High-throughput

0.445

High

878327

RIF1
Telomere-associated protein RIF1

1

0

High-throughput

0.438

High

148583

CTRO
Citron Rho-interacting kinase

1

4

High-throughput

0.437

High

352006

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.437

High

430902

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

1

High-throughput

0.437

High

530534

ITA4
Integrin alpha-4

1

1

High-throughput

0.437

High

878330

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

878341

CNTRB
Centrobin

1

2

High-throughput

0.437

High

878352

CHM4C
Charged multivesicular body protein 4c

1

4

High-throughput

0.437

High

878372

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

1

High-throughput

0.437

High

878380

HECD1
E3 ubiquitin-protein ligase HECTD1

1

10

High-throughput

0.437

High

217408

CHST1
Carbohydrate sulfotransferase 1

1

0

High-throughput

0.282

High

878359

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low

878307

IL16
Pro-interleukin-16 [Cleaved into: Interleukin-16

1

0

High-throughput

0.269

Low

126368

MATN2
Matrilin-2

1

0

High-throughput

0.249

Low

878340

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.249

Low

878354

KTI12
Protein KTI12 homolog

1

0

Small-scale

0.249

Low

878362

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

878367

NGB
Neuroglobin

1

0

High-throughput

0.249

Low

878376

C2D2A
Coiled-coil and C2 domain-containing protein 2A

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024