Protein: X2JCC3
poly(A)-specific ribonuclease (EC 3.1.13.4)

Gene: X2JCC3, Pop2
Organism: Drosophila melanogaster
Interactions: 63
UniProt ID: X2JCC3

Gene Ontology (top 5):
GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body
GO:0003676 - nucleic acid binding
GO:0004535 - poly(A)-specific ribonuclease activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

95530

E2QCN4
Not1, isoform F

4

8

Small-scale

0.873

High

62843

A4V4L0
Transducer of ERBB2, isoform E

2

20

Small-scale

0.757

High

1264603

Q7K112
poly(A)-specific ribonuclease

8

13

Small-scale

0.742

High

68209

A8DY81
Not1, isoform C

2

8

Small-scale

0.737

High

68210

A8DY82
Not1, isoform E

1

8

High-throughput

0.625

High

1237357

Q6NQY2
LD04013p

1

20

High-throughput

0.590

High

682694

PUM
Maternal protein pumilio

2

9

Small-scale

0.584

High

1264623

Q7K126
CCR4-NOT transcription complex subunit 3

2

11

Small-scale

0.571

High

1375093

RGA
Regulator of gene activity

2

10

Small-scale

0.571

High

121388

M9PF85
CCR4-NOT transcription complex subunit 9

1

5

Small-scale

0.479

High

636439

PABP
Polyadenylate-binding protein

1

2

Small-scale

0.479

High

1171469

SMG
Protein Smaug

1

1

Small-scale

0.479

High

1181175

Q32KD4
Protein argonaute-1

1

5

Small-scale

0.479

High

1268638

GGYF1
GIGYF family protein Gyf

1

2

Small-scale

0.479

High

1344097

GAWKY
Protein Gawky

1

6

Small-scale

0.479

High

1473026

Q9VEN9
Protein associated with topo II related - 1, isoform A

1

2

Small-scale

0.479

High

1487085

Q9VV48
RING-type E3 ubiquitin transferase

1

4

Small-scale

0.479

High

852543

CADF
Cofilin/actin-depolymerizing factor homolog

1

0

High-throughput

0.464

High

1481665

CUP
Protein cup

1

0

Small-scale

0.458

High

561871

MODU
DNA-binding protein modulo

1

3

High-throughput

0.445

High

1038273

IF4A
Eukaryotic initiation factor 4A

1

3

High-throughput

0.445

High

1064263

SQD
RNA-binding protein squid

1

2

High-throughput

0.445

High

1273674

AGO3
Protein argonaute-3

1

6

High-throughput

0.445

High

1303421

Q8IMW2
ubiquitinyl hydrolase 1

1

1

High-throughput

0.445

High

1475418

Q9VH01
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

1

High-throughput

0.445

High

1476701

IF4A3
Eukaryotic initiation factor 4A-III

1

2

High-throughput

0.445

High

53531

CP131
Centrosomal protein of 131 kDa

1

0

High-throughput

0.426

High

57476

A1ZB68
FI01423p

1

0

High-throughput

0.426

High

356083

EF1B
Probable elongation factor 1-beta

1

0

High-throughput

0.426

High

358564

ADH
Alcohol dehydrogenase

1

0

High-throughput

0.426

High

408241

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.426

High

714709

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.426

High

1202424

Q59E05
Transcription factor Ouib

1

0

High-throughput

0.426

High

1265941

MARS
Guanylate kinase-associated protein mars

1

0

High-throughput

0.426

High

1269737

Q7KUB1
Isocitrate dehydrogenase [NADP]

1

0

High-throughput

0.426

High

1305071

EXOS3
Exosome complex component RRP40

1

0

High-throughput

0.426

High

1305703

Q8IQX8
histidine--tRNA ligase

1

0

High-throughput

0.426

High

1471973

DMDA
Dystrophin, isoforms A/C/F/G/H

1

0

High-throughput

0.426

High

1477279

NOC3L
Nucleolar complex protein 3

1

0

High-throughput

0.426

High

1485828

Q9VSW5
Kinesin-like protein at 67A, isoform A

1

0

High-throughput

0.426

High

1489597

BGCN
Protein benign gonial cell neoplasm

1

0

High-throughput

0.426

High

1490113

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.426

High

1489650

Q9W1X5
GH04942p

1

3

High-throughput

0.407

High

809507

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.253

Low

1344766

Q8SZ78
Mayo

1

0

High-throughput

0.253

Low

930508

CNN
Centrosomin

1

0

High-throughput

0.232

Low

938954

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.232

Low

1177521

Q29QS8
IP11711p

1

0

High-throughput

0.232

Low

1268219

Q7KN94
Electron transfer flavoprotein subunit alpha

1

0

High-throughput

0.232

Low

1273647

Q7PLB8
Fatty acid synthase

1

0

High-throughput

0.232

Low

1468951

Q9VB64
Uridine diphosphate glucose pyrophosphatase NUDT14

1

0

High-throughput

0.232

Low

1470600

Q9VCN3
Glutamate dehydrogenase

1

0

High-throughput

0.232

Low

1471085

Q9VD22
LP02352p

1

0

High-throughput

0.232

Low

1471541

Q9VDF9
Uncharacterized protein

1

0

High-throughput

0.232

Low

1473926

CA131
Probable cytochrome P450 313a1

1

0

High-throughput

0.232

Low

1482312

Q9VN30
Sterile affecting ciliogenesis

1

0

High-throughput

0.232

Low

1483648

Q9VPW4
DNA-directed RNA polymerase

1

0

High-throughput

0.232

Low

1484436

Q9VQS4
Spindly

1

0

High-throughput

0.232

Low

1484938

Q9VRJ7
RE45108p

1

0

High-throughput

0.232

Low

1484957

Q9VRL0
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.232

Low

1488846

TXND5
Thioredoxin domain-containing protein 5 homolog

1

0

High-throughput

0.232

Low

1489551

Q9W1B9
Large ribosomal subunit protein uL11

1

0

High-throughput

0.232

Low

1489770

Q9W2J0
Uncharacterized protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025