Protein: TBL3
Transducin beta-like protein 3 (WD repeat-containing protein SAZD)

Gene: TBL3
Organism: Homo sapiens
Interactions: 158
UniProt ID: Q12788

Gene Ontology (top 5):
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1016302

WDR36
WD repeat-containing protein 36

2

18

High-throughput

0.789

High

1016345

WDR3
WD repeat-containing protein 3

2

18

High-throughput

0.789

High

1016340

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

2

8

High-throughput

0.776

High

787153

RHG25
Rho GTPase-activating protein 25

3

3

High-throughput

0.770

High

1016332

ANLN
Anillin

2

5

High-throughput

0.754

High

907871

RS16
Small ribosomal subunit protein uS9

1

9

High-throughput

0.691

High

1016282

PWP2
Periodic tryptophan protein 2 homolog

1

16

High-throughput

0.691

High

1016285

IF16
Gamma-interferon-inducible protein 16

3

8

High-throughput

0.656

High

1016307

APBP2
Amyloid protein-binding protein 2

2

5

High-throughput

0.646

High

418212

NPM
Nucleophosmin

2

6

High-throughput

0.628

High

642828

3BHS2
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2

2

2

High-throughput

0.628

High

1016321

RBM4
RNA-binding protein 4

2

18

High-throughput

0.628

High

615400

KALM
Anosmin-1

1

2

High-throughput

0.618

High

268049

EED
Polycomb protein EED

1

19

High-throughput

0.618

High

827922

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

16

High-throughput

0.618

High

903174

WDR5
WD repeat-containing protein 5

1

16

High-throughput

0.618

High

1016284

DDB1
DNA damage-binding protein 1

1

11

Small-scale

0.618

High

1016301

NUP43
Nucleoporin Nup43

1

18

High-throughput

0.618

High

1016312

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

17

High-throughput

0.618

High

1016329

RC3H2
Roquin-2

1

7

High-throughput

0.618

High

1016334

DCA13
DDB1- and CUL4-associated factor 13

1

16

Small-scale

0.618

High

133462

NOP56
Nucleolar protein 56

2

11

High-throughput

0.611

High

850019

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

10

High-throughput

0.590

High

244350

BRD4
Bromodomain-containing protein 4

2

20

High-throughput

0.584

High

322532

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

18

High-throughput

0.584

High

346638

MYC
Myc proto-oncogene protein

2

20

High-throughput

0.584

High

603471

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

10

High-throughput

0.584

High

916542

RS6
Small ribosomal subunit protein eS6

2

6

High-throughput

0.584

High

369488

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

728908

AHR
Aryl hydrocarbon receptor

1

5

Small-scale

0.561

High

1016274

CUL4B
Cullin-4B

1

20

Small-scale

0.561

High

428163

TBB5
Tubulin beta chain

2

12

High-throughput

0.558

High

148734

CTRO
Citron Rho-interacting kinase

1

9

High-throughput

0.553

High

870778

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

9

High-throughput

0.553

High

908449

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

14

High-throughput

0.553

High

1016293

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.553

High

1016298

RHG24
Rho GTPase-activating protein 24

1

3

High-throughput

0.553

High

1016322

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

2

High-throughput

0.553

High

1016326

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.553

High

196085

RRP8
Ribosomal RNA-processing protein 8

1

4

High-throughput

0.536

High

273090

SURF6
Surfeit locus protein 6

1

3

High-throughput

0.536

High

736420

RL4
Large ribosomal subunit protein uL4

1

9

High-throughput

0.536

High

781730

MNDA
Myeloid cell nuclear differentiation antigen

1

8

High-throughput

0.536

High

801104

KI67
Proliferation marker protein Ki-67

1

12

High-throughput

0.536

High

962036

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

16

High-throughput

0.536

High

975421

PPARD
Peroxisome proliferator-activated receptor delta

1

16

High-throughput

0.536

High

1016304

PSPC1
Paraspeckle component 1

1

20

High-throughput

0.536

High

1016316

MPH6
M-phase phosphoprotein 6

1

2

High-throughput

0.536

High

1016317

RBM4B
RNA-binding protein 4B

1

19

High-throughput

0.536

High

1016330

EXOS4
Exosome complex component RRP41

1

11

High-throughput

0.536

High

1016331

EXOS5
Exosome complex component RRP46

1

14

High-throughput

0.536

High

1016344

G3BP2
Ras GTPase-activating protein-binding protein 2

1

11

High-throughput

0.536

High

1016350

EXOS1
Exosome complex component CSL4

1

6

High-throughput

0.536

High

255726

OBSL1
Obscurin-like protein 1

2

5

High-throughput

0.533

High

1016278

CUL7
Cullin-7

2

3

High-throughput

0.533

High

834274

PSN1
Presenilin-1

1

0

High-throughput

0.513

High

684000

1433S
14-3-3 protein sigma

1

16

High-throughput

0.494

High

1016339

ITSN2
Intersectin-2

1

6

High-throughput

0.494

High

180299

MAGB2
Melanoma-associated antigen B2

1

7

High-throughput

0.489

High

243379

DNJA2
DnaJ homolog subfamily A member 2

1

12

High-throughput

0.489

High

276235

CIB2
Calcium and integrin-binding family member 2

1

3

High-throughput

0.489

High

311693

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

1

High-throughput

0.489

High

323715

BAG2
BAG family molecular chaperone regulator 2

1

3

High-throughput

0.489

High

1016286

RTN1
Reticulon-1

1

1

High-throughput

0.489

High

1016296

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

1

High-throughput

0.489

High

1016315

TECTB
Beta-tectorin

1

3

High-throughput

0.489

High

1016319

AFG2B
ATPase family gene 2 protein homolog B

1

10

High-throughput

0.489

High

1016346

SRPK3
SRSF protein kinase 3

1

20

High-throughput

0.489

High

1016349

KLH20
Kelch-like protein 20

1

5

High-throughput

0.489

High

122705

MEN1
Menin

1

4

High-throughput

0.479

High

126125

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

9

Small-scale

0.479

High

179617

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

2

High-throughput

0.479

High

205333

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

209933

PRC1
Protein regulator of cytokinesis 1

1

7

High-throughput

0.479

High

214233

SPOP
Speckle-type POZ protein

1

8

High-throughput

0.479

High

233406

NUPR1
Nuclear protein 1

1

3

High-throughput

0.479

High

257997

DNJB6
DnaJ homolog subfamily B member 6

1

11

High-throughput

0.479

High

278799

DNJC8
DnaJ homolog subfamily C member 8

1

12

High-throughput

0.479

High

308656

KI20A
Kinesin-like protein KIF20A

1

18

High-throughput

0.479

High

377280

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

386621

P53
Cellular tumor antigen p53

1

12

High-throughput

0.479

High

455366

PARP1
Poly [ADP-ribose] polymerase 1

1

8

High-throughput

0.479

High

552587

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.479

High

651059

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

684668

STIP1
Stress-induced-phosphoprotein 1

1

13

High-throughput

0.479

High

720327

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.479

High

749427

BRCA1
Breast cancer type 1 susceptibility protein

1

8

High-throughput

0.479

High

817979

SOX2
Transcription factor SOX-2

1

14

High-throughput

0.479

High

823936

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

10

High-throughput

0.479

High

877712

FOXA1
Hepatocyte nuclear factor 3-alpha

1

9

High-throughput

0.479

High

917174

H4
Histone H4

1

6

High-throughput

0.479

High

920159

RS24
Small ribosomal subunit protein eS24

1

4

High-throughput

0.479

High

922138

RL31
Large ribosomal subunit protein eL31

1

3

High-throughput

0.479

High

940832

RNF4
E3 ubiquitin-protein ligase RNF4

1

10

High-throughput

0.479

High

966394

EXOSX
Exosome complex component 10

1

6

High-throughput

0.479

High

969651

KIF23
Kinesin-like protein KIF23

1

12

High-throughput

0.479

High

974542

MECOM
Histone-lysine N-methyltransferase MECOM

1

1

High-throughput

0.479

High

1016271

GRSF1
G-rich sequence factor 1

1

20

High-throughput

0.479

High

1016272

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

12

High-throughput

0.479

High

1016273

BIRC3
Baculoviral IAP repeat-containing protein 3

1

7

High-throughput

0.479

High

1016277

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

13

High-throughput

0.479

High

1016279

TNIP1
TNFAIP3-interacting protein 1

1

12

High-throughput

0.479

High

1016283

E2F4
Transcription factor E2F4

1

5

High-throughput

0.479

High

1016289

RC3H1
Roquin-1

1

3

High-throughput

0.479

High

1016290

IFIX
Pyrin and HIN domain-containing protein 1

1

8

High-throughput

0.479

High

1016291

ZN746
Zinc finger protein 746

1

3

High-throughput

0.479

High

1016295

ZCH18
Zinc finger CCCH domain-containing protein 18

1

13

High-throughput

0.479

High

1016297

SMC5
Structural maintenance of chromosomes protein 5

1

3

High-throughput

0.479

High

1016300

SIR6
NAD-dependent protein deacylase sirtuin-6

1

9

High-throughput

0.479

High

1016303

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

1016305

DNJC9
DnaJ homolog subfamily C member 9

1

16

High-throughput

0.479

High

1016308

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1016309

CHCH1
Small ribosomal subunit protein mS37

1

2

High-throughput

0.479

High

1016310

DCPS
m7GpppX diphosphatase

1

1

High-throughput

0.479

High

1016314

DDRGK
DDRGK domain-containing protein 1

1

6

High-throughput

0.479

High

1016320

DDA1
DET1- and DDB1-associated protein 1

1

1

High-throughput

0.479

High

1016324

XRN2
5'-3' exoribonuclease 2

1

2

High-throughput

0.479

High

1016327

ECT2
Protein ECT2

1

13

High-throughput

0.479

High

1016328

PRD16
Histone-lysine N-methyltransferase PRDM16

1

1

High-throughput

0.479

High

1016333

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

9

High-throughput

0.479

High

1016335

DJC17
DnaJ homolog subfamily C member 17

1

17

High-throughput

0.479

High

1016337

AATF
Protein AATF

1

9

High-throughput

0.479

High

1016338

TLS1
Splicing factor C9orf78

1

4

High-throughput

0.479

High

1016347

CE164
Centrosomal protein of 164 kDa

1

15

High-throughput

0.479

High

1016348

NUDC
Nuclear migration protein nudC

1

10

High-throughput

0.479

High

274086

XRP2
Protein XRP2

1

0

High-throughput

0.458

High

1016275

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

1016287

MIDN
Midnolin

1

0

High-throughput

0.458

High

1016313

AURKB
Aurora kinase B

1

13

High-throughput

0.457

High

401905

JUN
Transcription factor Jun

1

12

High-throughput

0.445

High

853872

NCBP2
Nuclear cap-binding protein subunit 2

1

15

High-throughput

0.445

High

1016276

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

7

High-throughput

0.445

High

125414

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

12

High-throughput

0.437

High

227292

PRKN
E3 ubiquitin-protein ligase parkin

1

20

High-throughput

0.437

High

297610

RHBT1
Rho-related BTB domain-containing protein 1

1

12

High-throughput

0.437

High

338342

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.437

High

384733

NTRK1
High affinity nerve growth factor receptor

1

6

High-throughput

0.437

High

726176

BASI
Basigin

1

3

High-throughput

0.437

High

779311

CCNF
Cyclin-F

1

9

High-throughput

0.437

High

1016280

KIF14
Kinesin-like protein KIF14

1

8

High-throughput

0.437

High

1016281

BRD3
Bromodomain-containing protein 3

1

20

High-throughput

0.437

High

1016299

FA43A
Protein FAM43A

1

4

High-throughput

0.437

High

1016311

CHM4C
Charged multivesicular body protein 4c

1

8

High-throughput

0.437

High

1016323

RHBT2
Rho-related BTB domain-containing protein 2

1

12

High-throughput

0.437

High

1016325

CHM4B
Charged multivesicular body protein 4b

1

8

High-throughput

0.437

High

1016341

KLK11
Kallikrein-11

1

3

High-throughput

0.437

High

1016343

HECD1
E3 ubiquitin-protein ligase HECTD1

1

17

High-throughput

0.437

High

1016288

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

High-throughput

0.407

High

1016342

DKKL1
Dickkopf-like protein 1

2

0

High-throughput

0.328

High

124978

CACB4
Voltage-dependent L-type calcium channel subunit beta-4

1

0

High-throughput

0.282

High

942502

CTG1B
Cancer/testis antigen 1

1

0

High-throughput

0.279

Low

996096

HDHD1
Pseudouridine-5'-phosphatase

1

0

High-throughput

0.279

Low

1016294

GOGA7
Golgin subfamily A member 7

1

0

High-throughput

0.279

Low

1016336

FAIM1
Fas apoptotic inhibitory molecule 1

1

0

High-throughput

0.279

Low

1016351

WIF1
Wnt inhibitory factor 1

1

0

High-throughput

0.279

Low

1016292

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1016306

DNS2B
Deoxyribonuclease-2-beta

1

0

High-throughput

0.249

Low

1016318

URM1
Ubiquitin-related modifier 1

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024