Protein: FBX3
F-box only protein 3

Gene: FBX3, FBXO3
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q9UK99

Gene Ontology (top 5):
GO:0004842 - ubiquitin-protein transferase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

929107

SKP1
S-phase kinase-associated protein 1

14

5

Small-scale

0.981

High

1041263

CUL1
Cullin-1

7

3

Small-scale

0.963

High

1042808

CUL3
Cullin-3

2

3

High-throughput

0.789

High

1356338

FBXL2
F-box/LRR-repeat protein 2

3

0

Small-scale

0.784

High

229020

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.754

High

606947

IDS
Iduronate 2-sulfatase

3

3

High-throughput

0.667

High

1079629

NEDD8
NEDD8

1

0

High-throughput

0.656

High

921469

RBX1
E3 ubiquitin-protein ligase RBX1

4

0

Small-scale

0.648

High

1356337

FBX3
F-box only protein 3

1

1

High-throughput

0.618

High

476546

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.614

High

56555

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

2

5

High-throughput

0.611

High

1356340

ARI1
E3 ubiquitin-protein ligase ARIH1

2

1

High-throughput

0.611

High

780296

CCNF
Cyclin-F

1

0

High-throughput

0.586

High

999193

EP300
Histone acetyltransferase p300

2

1

Small-scale

0.584

High

1043296

CUL4A
Cullin-4A

1

3

High-throughput

0.575

High

1336109

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

0

Small-scale

0.554

High

215550

CF410
Cilia- and flagella-associated protein 410

1

0

Small-scale

0.537

High

305042

DUS14
Dual specificity protein phosphatase 14

1

1

High-throughput

0.536

High

1219102

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

707401

S10A3
Protein S100-A3

1

0

High-throughput

0.513

High

738818

SPB5
Serpin B5

1

0

High-throughput

0.513

High

846045

PLCD1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

1

0

High-throughput

0.513

High

1251941

RIN3
Ras and Rab interactor 3

1

0

High-throughput

0.513

High

1272689

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.513

High

1289642

ARSG
Arylsulfatase G

1

3

High-throughput

0.489

High

149405

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

217509

AIRE
Autoimmune regulator

1

1

Small-scale

0.479

High

432346

HS90A
Heat shock protein HSP 90-alpha

1

1

High-throughput

0.479

High

438604

HS90B
Heat shock protein HSP 90-beta

1

1

High-throughput

0.479

High

599745

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

2

High-throughput

0.479

High

669058

PML
Protein PML

1

1

Small-scale

0.479

High

832770

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

1064820

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

3

High-throughput

0.479

High

1144648

TENS2
Tensin-2

1

2

High-throughput

0.479

High

1159330

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

High-throughput

0.479

High

1292282

AURKB
Aurora kinase B

1

1

High-throughput

0.479

High

1329782

HIPK2
Homeodomain-interacting protein kinase 2

1

1

Small-scale

0.479

High

1331587

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

1344016

BIRC6
Baculoviral IAP repeat-containing protein 6

1

1

Small-scale

0.479

High

1354800

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1355823

HERC5
E3 ISG15--protein ligase HERC5

1

1

Small-scale

0.479

High

1356341

DUS10
Dual specificity protein phosphatase 10

1

1

High-throughput

0.479

High

157256

BACH1
Transcription regulator protein BACH1

1

0

Small-scale

0.458

High

295379

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

896255

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

988817

PAX8
Paired box protein Pax-8

1

0

Small-scale

0.458

High

1036985

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1158342

CDC73
Parafibromin

1

0

High-throughput

0.458

High

1215891

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.458

High

1296357

TNIP3
TNFAIP3-interacting protein 3

1

0

High-throughput

0.458

High

1296954

SNX27
Sorting nexin-27

1

0

High-throughput

0.458

High

1318766

IN80B
INO80 complex subunit B

1

0

High-throughput

0.458

High

1332749

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1335229

RC3H2
Roquin-2

1

1

High-throughput

0.437

High

1355573

ZNHI2
Zinc finger HIT domain-containing protein 2

1

1

High-throughput

0.437

High

1185008

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.426

High

1295610

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.426

High

648633

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.279

Low

1048817

TRI29
Tripartite motif-containing protein 29

1

0

High-throughput

0.279

Low

1128588

CAHM4
Calcium homeostasis modulator protein 4

1

0

High-throughput

0.279

Low

1146478

ATG9B
Autophagy-related protein 9B

1

0

High-throughput

0.279

Low

1154398

HPHL1
Ferroxidase HEPHL1

1

0

High-throughput

0.279

Low

1197778

DSG4
Desmoglein-4

1

0

High-throughput

0.279

Low

1257263

LRC15
Leucine-rich repeat-containing protein 15

1

0

High-throughput

0.279

Low

1356339

CRBG1
Beta/gamma crystallin domain-containing protein 1

1

0

High-throughput

0.279

Low

484343

VSIG8
V-set and immunoglobulin domain-containing protein 8

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024