Protein: MVP
Major vault protein (MVP) (Lung resistance-related protein)

Gene: MVP
Organism: Homo sapiens
Interactions: 161
UniProt ID: Q14764

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005643 - nuclear pore
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1058926

MVP
Major vault protein

5

1

High-throughput

0.928

High

1058993

PARP4
Protein mono-ADP-ribosyltransferase PARP4

4

0

Small-scale

0.670

High

1058958

COP1
E3 ubiquitin-protein ligase COP1

3

1

Small-scale

0.667

High

1058981

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

2

0

High-throughput

0.602

High

1058988

RCOR3
REST corepressor 3

2

0

High-throughput

0.602

High

1058994

DD19B
ATP-dependent RNA helicase DDX19B

2

0

High-throughput

0.585

High

170071

PLS1
Phospholipid scramblase 1

2

1

High-throughput

0.584

High

1058932

NRF1
Nuclear respiratory factor 1

2

0

High-throughput

0.580

High

1058935

FND3B
Fibronectin type III domain-containing protein 3B

2

0

High-throughput

0.580

High

1058949

DTX2
Probable E3 ubiquitin-protein ligase DTX2

2

0

High-throughput

0.580

High

1058960

UBTD2
Ubiquitin domain-containing protein 2

2

0

High-throughput

0.580

High

1058967

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

1058976

TOLIP
Toll-interacting protein

2

0

High-throughput

0.580

High

529126

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.576

High

369617

ESR1
Estrogen receptor

1

1

Small-scale

0.561

High

1058983

ANLN
Anillin

2

0

High-throughput

0.559

High

890666

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.549

High

235078

DOK2
Docking protein 2

2

0

High-throughput

0.547

High

592256

RAB5A
Ras-related protein Rab-5A

2

0

High-throughput

0.547

High

821852

HSP13
Heat shock 70 kDa protein 13

1

1

High-throughput

0.541

High

843677

FXR1
RNA-binding protein FXR1

1

2

High-throughput

0.541

High

844065

FXR2
RNA-binding protein FXR2

1

2

High-throughput

0.541

High

988885

FMR1
Fragile X messenger ribonucleoprotein 1

1

2

High-throughput

0.541

High

626313

CO8A2
Collagen alpha-2(VIII) chain

1

1

High-throughput

0.536

High

995367

LG3BP
Galectin-3-binding protein

1

1

High-throughput

0.536

High

1052059

MAP7
Ensconsin

1

2

High-throughput

0.536

High

883017

H2BFS
Histone H2B type F-S

1

4

High-throughput

0.515

High

886108

H2B1D
Histone H2B type 1-D

1

4

High-throughput

0.515

High

1058934

H2B2E
Histone H2B type 2-E

1

4

High-throughput

0.515

High

1058937

H2B2F
Histone H2B type 2-F

1

4

High-throughput

0.515

High

1058964

H2B1H
Histone H2B type 1-H

1

4

High-throughput

0.515

High

504091

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.513

High

565925

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.513

High

573696

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.513

High

602839

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

0

High-throughput

0.513

High

849892

STA5B
Signal transducer and activator of transcription 5B

1

0

High-throughput

0.513

High

882735

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

958683

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.513

High

960796

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.513

High

1039561

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.513

High

1058969

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

1058987

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.513

High

1052393

FLOT2
Flotillin-2

1

0

High-throughput

0.493

High

131435

IMA4
Importin subunit alpha-4

1

2

High-throughput

0.481

High

207800

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

1

2

High-throughput

0.481

High

305106

RIMB1
Peripheral-type benzodiazepine receptor-associated protein 1

1

3

High-throughput

0.481

High

386743

P53
Cellular tumor antigen p53

1

1

High-throughput

0.481

High

521357

SKIL
Ski-like protein

1

2

High-throughput

0.481

High

536833

TRI27
Zinc finger protein RFP

1

1

High-throughput

0.481

High

551147

ITF2
Transcription factor 4

1

1

High-throughput

0.481

High

837801

MEOX1
Homeobox protein MOX-1

1

7

High-throughput

0.481

High

837974

MEOX2
Homeobox protein MOX-2

1

7

High-throughput

0.481

High

853283

IMA1
Importin subunit alpha-1

1

2

High-throughput

0.481

High

981580

REL
Proto-oncogene c-Rel

1

1

High-throughput

0.481

High

990448

CKAP4
Cytoskeleton-associated protein 4

1

2

High-throughput

0.481

High

991933

DLX2
Homeobox protein DLX-2

1

1

High-throughput

0.481

High

993423

TLE5
TLE family member 5

1

2

High-throughput

0.481

High

994874

GOGA2
Golgin subfamily A member 2

1

1

High-throughput

0.481

High

997370

VAC14
Protein VAC14 homolog

1

1

High-throughput

0.481

High

1016771

TFCP2
Alpha-globin transcription factor CP2

1

1

High-throughput

0.481

High

1020663

TRAF2
TNF receptor-associated factor 2

1

4

High-throughput

0.481

High

1025386

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

4

High-throughput

0.481

High

1038871

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

1

High-throughput

0.481

High

1058929

PCH2
Pachytene checkpoint protein 2 homolog

1

2

High-throughput

0.481

High

1058930

TRIP6
Thyroid receptor-interacting protein 6

1

1

High-throughput

0.481

High

1058938

TET5C
Terminal nucleotidyltransferase 5C

1

2

High-throughput

0.481

High

1058944

ATL4
ADAMTS-like protein 4

1

1

High-throughput

0.481

High

1058948

NT2NA
Notch homolog 2 N-terminal-like protein A

1

1

High-throughput

0.481

High

1058952

SAXO1
Stabilizer of axonemal microtubules 1

1

1

High-throughput

0.481

High

1058956

ZMIZ2
Zinc finger MIZ domain-containing protein 2

1

1

High-throughput

0.481

High

1058962

PIHD2
PIH1 domain-containing protein 2

1

1

High-throughput

0.481

High

1058963

RBPMS
RNA-binding protein with multiple splicing

1

2

High-throughput

0.481

High

1058966

MRTFA
Myocardin-related transcription factor A

1

1

High-throughput

0.481

High

1058968

RAB3I
Rab-3A-interacting protein

1

1

High-throughput

0.481

High

1058971

MDFI
MyoD family inhibitor

1

2

High-throughput

0.481

High

1058973

RHXF2
Rhox homeobox family member 2

1

1

High-throughput

0.481

High

1058979

STN1
CST complex subunit STN1

1

1

High-throughput

0.481

High

1058985

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.481

High

1058989

RIM3A
RIMS-binding protein 3A

1

3

High-throughput

0.481

High

1058990

SRTD1
SERTA domain-containing protein 1

1

1

High-throughput

0.481

High

1058991

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

6

High-throughput

0.481

High

1058996

ZBT32
Zinc finger and BTB domain-containing protein 32

1

2

High-throughput

0.481

High

475766

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

130891

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

1

High-throughput

0.479

High

177025

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

1

Small-scale

0.479

High

301818

TRI37
E3 ubiquitin-protein ligase TRIM37

1

3

High-throughput

0.479

High

521270

SKI
Ski oncogene

1

2

Small-scale

0.479

High

538797

GLUT4
Solute carrier family 2, facilitated glucose transporter member 4

1

1

High-throughput

0.479

High

749502

BRCA1
Breast cancer type 1 susceptibility protein

1

2

High-throughput

0.479

High

980688

TLE2
Transducin-like enhancer protein 2

1

2

High-throughput

0.479

High

1027999

ERCC8
DNA excision repair protein ERCC-8

1

1

Small-scale

0.479

High

1058927

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

1058946

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

1058972

TEP1
Telomerase protein component 1

1

1

Small-scale

0.479

High

1058997

LOXL2
Lysyl oxidase homolog 2

1

1

High-throughput

0.479

High

1058998

TRAF6
TNF receptor-associated factor 6

1

5

Small-scale

0.479

High

341205

HPT
Haptoglobin

1

0

High-throughput

0.460

High

713758

HYES
Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2

1

0

High-throughput

0.460

High

1033777

NNTM
NAD(P) transhydrogenase, mitochondrial

1

0

High-throughput

0.460

High

1058945

RN111
E3 ubiquitin-protein ligase Arkadia

1

0

High-throughput

0.460

High

122762

MEN1
Menin

1

0

High-throughput

0.458

High

125462

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

128180

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

0

High-throughput

0.458

High

160568

AURKA
Aurora kinase A

1

0

High-throughput

0.458

High

234337

GSDME
Gasdermin-E

1

0

Small-scale

0.458

High

236762

CCNT1
Cyclin-T1

1

0

High-throughput

0.458

High

325733

LATS1
Serine/threonine-protein kinase LATS1

1

0

High-throughput

0.458

High

346801

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

352615

TNFA
Tumor necrosis factor

1

0

High-throughput

0.458

High

450880

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.458

High

575437

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

610405

CBL
E3 ubiquitin-protein ligase CBL

1

0

High-throughput

0.458

High

641775

U2AF2
Splicing factor U2AF 65 kDa subunit

1

0

High-throughput

0.458

High

719492

MERL
Merlin

1

0

High-throughput

0.458

High

799103

NKX21
Homeobox protein Nkx-2.1

1

0

High-throughput

0.458

High

832465

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

835762

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.458

High

917273

H4
Histone H4

1

0

High-throughput

0.458

High

927050

1433Z
14-3-3 protein zeta/delta

1

0

High-throughput

0.458

High

957706

XIAP
E3 ubiquitin-protein ligase XIAP

1

0

Small-scale

0.458

High

969699

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

1058928

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1058931

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1058933

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

Small-scale

0.458

High

1058936

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.458

High

1058939

CD276
CD276 antigen

1

0

Small-scale

0.458

High

1058943

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

1058953

CMTR1
Cap-specific mRNA

1

0

High-throughput

0.458

High

1058954

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

1058959

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1058961

NUDC2
NudC domain-containing protein 2

1

0

High-throughput

0.458

High

1058965

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

1058974

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

1058975

ACE2
Angiotensin-converting enzyme 2

1

0

Small-scale

0.458

High

1058977

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

1058978

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

0

Small-scale

0.458

High

1058980

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

1058982

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

1058984

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

1058992

TNIK
TRAF2 and NCK-interacting protein kinase

1

0

High-throughput

0.458

High

1058940

Q6FHY5
MEOX2 protein

1

7

High-throughput

0.457

High

1058941

PKHA7
Pleckstrin homology domain-containing family A member 7

1

1

High-throughput

0.445

High

1058970

ZBT18
Zinc finger and BTB domain-containing protein 18

1

1

High-throughput

0.445

High

1058942

CA094
Uncharacterized protein C1orf94

1

1

High-throughput

0.439

High

1058947

KCTD9
BTB/POZ domain-containing protein KCTD9

1

1

High-throughput

0.439

High

1058950

TRI42
Tripartite motif-containing protein 42

1

6

High-throughput

0.439

High

1058951

IHO1
Interactor of HORMAD1 protein 1

1

1

High-throughput

0.439

High

1058955

BANP
Protein BANP

1

1

High-throughput

0.439

High

358514

CO1A1
Collagen alpha-1(I) chain

1

0

Small-scale

0.426

High

717830

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.426

High

905900

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

0

High-throughput

0.426

High

1032410

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.426

High

1043799

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.426

High

1047083

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

1058957

MSPD2
Motile sperm domain-containing protein 2

1

0

High-throughput

0.426

High

239997

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.279

Low

1058995

COLQ
Acetylcholinesterase collagenic tail peptide

1

0

High-throughput

0.279

Low

333460

CYB
Cytochrome b

1

0

High-throughput

0.251

Low

1050105

GIT2
ARF GTPase-activating protein GIT2

1

0

High-throughput

0.251

Low

1058986

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024