Protein: SAFB1
Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein)

Gene: SAFB1, SAFB
Organism: Homo sapiens
Interactions: 188
UniProt ID: Q15424

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003682 - chromatin binding
GO:0003690 - double-stranded DNA binding
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

453376

ROA1
Heterogeneous nuclear ribonucleoprotein A1

4

20

Small-scale

0.890

High

726839

FUS
RNA-binding protein FUS

3

20

Small-scale

0.865

High

1073539

RBP56
TATA-binding protein-associated factor 2N

2

12

Small-scale

0.815

High

1018498

CHD3
Chromodomain-helicase-DNA-binding protein 3

2

10

High-throughput

0.793

High

1073548

SRPK1
SRSF protein kinase 1

2

20

Small-scale

0.783

High

1049463

SAFB2
Scaffold attachment factor B2

1

18

Small-scale

0.740

High

1073559

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

2

5

High-throughput

0.737

High

934186

CSK21
Casein kinase II subunit alpha

1

7

High-throughput

0.735

High

1073536

SREK1
Splicing regulatory glutamine/lysine-rich protein 1

1

5

Small-scale

0.724

High

414930

CDK1
Cyclin-dependent kinase 1

1

3

High-throughput

0.691

High

446647

SNRPA
U1 small nuclear ribonucleoprotein A

1

18

High-throughput

0.691

High

745180

RBMX
RNA-binding motif protein, X chromosome

1

18

High-throughput

0.691

High

824639

MAPK2
MAP kinase-activated protein kinase 2

1

2

High-throughput

0.691

High

1020262

ELAV2
ELAV-like protein 2

1

18

High-throughput

0.691

High

1030257

G3BP1
Ras GTPase-activating protein-binding protein 1

1

17

High-throughput

0.691

High

1047566

KGP1
cGMP-dependent protein kinase 1

1

10

High-throughput

0.691

High

1073507

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

11

High-throughput

0.691

High

1073546

RBM14
RNA-binding protein 14

1

18

High-throughput

0.691

High

1073552

RBM4B
RNA-binding protein 4B

1

18

High-throughput

0.691

High

1048071

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

19

Small-scale

0.680

High

369663

ESR1
Estrogen receptor

3

20

Small-scale

0.667

High

942678

SRPK2
SRSF protein kinase 2

1

20

High-throughput

0.647

High

346856

MYC
Myc proto-oncogene protein

3

16

High-throughput

0.640

High

261517

NCOR1
Nuclear receptor corepressor 1

2

6

Small-scale

0.631

High

833740

CLK1
Dual specificity protein kinase CLK1

1

20

Small-scale

0.621

High

160580

AURKA
Aurora kinase A

1

12

High-throughput

0.618

High

442177

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

18

High-throughput

0.618

High

841742

CDK9
Cyclin-dependent kinase 9

1

9

High-throughput

0.618

High

967196

EWS
RNA-binding protein EWS

1

12

High-throughput

0.618

High

1029453

TIF1B
Transcription intermediary factor 1-beta

1

9

Small-scale

0.618

High

1054335

RBM39
RNA-binding protein 39

1

17

High-throughput

0.618

High

1059632

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

10

High-throughput

0.618

High

1073570

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

4

Small-scale

0.618

High

793973

MATR3
Matrin-3

2

11

High-throughput

0.611

High

1073516

IFIX
Pyrin and HIN domain-containing protein 1

2

12

High-throughput

0.611

High

1073558

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

3

15

High-throughput

0.590

High

177302

HDAC3
Histone deacetylase 3

2

6

Small-scale

0.584

High

244480

BRD4
Bromodomain-containing protein 4

2

8

High-throughput

0.584

High

940937

RNF4
E3 ubiquitin-protein ligase RNF4

2

3

Small-scale

0.584

High

1073563

ANLN
Anillin

2

7

High-throughput

0.584

High

853903

NCBP2
Nuclear cap-binding protein subunit 2

1

19

High-throughput

0.575

High

998062

NCBP1
Nuclear cap-binding protein subunit 1

1

4

High-throughput

0.575

High

1043815

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

13

High-throughput

0.575

High

1073534

RBCC1
RB1-inducible coiled-coil protein 1

2

14

High-throughput

0.558

High

148854

CTRO
Citron Rho-interacting kinase

1

12

High-throughput

0.553

High

157044

AIM2
Interferon-inducible protein AIM2

1

12

High-throughput

0.536

High

256261

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

11

High-throughput

0.536

High

440527

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

2

High-throughput

0.536

High

448663

RU1C
U1 small nuclear ribonucleoprotein C

1

2

High-throughput

0.536

High

449731

HMGB1
High mobility group protein B1

1

20

High-throughput

0.536

High

508545

TOP1
DNA topoisomerase 1

1

4

High-throughput

0.536

High

538969

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

3

High-throughput

0.536

High

601255

VDAC1
Voltage-dependent anion-selective channel protein 1

1

4

High-throughput

0.536

High

739127

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.536

High

887552

APC15
Anaphase-promoting complex subunit 15

1

2

High-throughput

0.536

High

906469

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

13

High-throughput

0.536

High

996685

SSRP1
FACT complex subunit SSRP1

1

20

High-throughput

0.536

High

1041637

CUL3
Cullin-3

1

20

High-throughput

0.536

High

1068195

PEA15
Astrocytic phosphoprotein PEA-15

1

3

High-throughput

0.536

High

1073509

IF16
Gamma-interferon-inducible protein 16

1

12

High-throughput

0.536

High

1073520

COX15
Heme A synthase COX15

1

3

High-throughput

0.536

High

1073550

MPP8
M-phase phosphoprotein 8

1

11

High-throughput

0.536

High

1073560

P63
Tumor protein 63

1

6

Small-scale

0.536

High

1073564

DDX21
Nucleolar RNA helicase 2

1

9

High-throughput

0.536

High

386786

P53
Cellular tumor antigen p53

1

6

Small-scale

0.534

High

411731

LCK
Tyrosine-protein kinase Lck

2

7

High-throughput

0.521

High

1073561

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

2

15

Small-scale

0.521

High

328855

TOP3B
DNA topoisomerase 3-beta-1

1

2

High-throughput

0.515

High

429898

CATL1
Procathepsin L

1

2

High-throughput

0.515

High

499766

CH60
60 kDa heat shock protein, mitochondrial

1

4

High-throughput

0.515

High

1073519

UBP45
Ubiquitin carboxyl-terminal hydrolase 45

1

2

High-throughput

0.515

High

1073532

KRI1
Protein KRI1 homolog

1

1

High-throughput

0.515

High

1073512

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

Small-scale

0.514

High

1073547

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

3

High-throughput

0.504

High

902601

SUMO2
Small ubiquitin-related modifier 2

1

5

High-throughput

0.501

High

601518

FGFR2
Fibroblast growth factor receptor 2

1

20

High-throughput

0.500

High

1073566

EPHA6
Ephrin type-A receptor 6

1

17

High-throughput

0.500

High

128570

DNM1L
Dynamin-1-like protein

1

1

High-throughput

0.489

High

255154

ATG13
Autophagy-related protein 13

1

3

High-throughput

0.489

High

427893

CAN1
Calpain-1 catalytic subunit

1

5

High-throughput

0.489

High

483480

SAA1
Serum amyloid A-1 protein

1

2

High-throughput

0.489

High

666604

LTK
Leukocyte tyrosine kinase receptor

1

15

High-throughput

0.489

High

1073517

CAN13
Calpain-13

1

5

High-throughput

0.489

High

1073529

CT197
Putative uncharacterized protein encoded by LINC02910

1

2

High-throughput

0.489

High

1073542

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

2

High-throughput

0.489

High

1073544

ERLEC
Endoplasmic reticulum lectin 1

1

1

High-throughput

0.489

High

1073553

ATGA1
Autophagy-related protein 101

1

1

High-throughput

0.489

High

1073573

KLH20
Kelch-like protein 20

1

4

High-throughput

0.489

High

151416

CHD1
Chromodomain-helicase-DNA-binding protein 1

1

10

Small-scale

0.481

High

122777

MEN1
Menin

1

5

High-throughput

0.479

High

125478

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

6

High-throughput

0.479

High

177898

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.479

High

210019

PRC1
Protein regulator of cytokinesis 1

1

7

High-throughput

0.479

High

227532

PRKN
E3 ubiquitin-protein ligase parkin

1

17

High-throughput

0.479

High

233468

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

268110

EED
Polycomb protein EED

1

15

High-throughput

0.479

High

278093

PIAS1
E3 SUMO-protein ligase PIAS1

1

1

Small-scale

0.479

High

308735

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

322673

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

20

High-throughput

0.479

High

379434

MYCN
N-myc proto-oncogene protein

1

15

High-throughput

0.479

High

450884

F16P1
Fructose-1,6-bisphosphatase 1

1

2

High-throughput

0.479

High

504120

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

552802

RFA2
Replication protein A 32 kDa subunit

1

13

High-throughput

0.479

High

590945

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

615743

GCSP
Glycine dehydrogenase

1

2

High-throughput

0.479

High

651284

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

668706

PML
Protein PML

1

11

High-throughput

0.479

High

669377

EF1D
Elongation factor 1-delta

1

1

High-throughput

0.479

High

720539

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.479

High

798906

GATA4
Transcription factor GATA-4

1

3

High-throughput

0.479

High

801888

RECQ1
ATP-dependent DNA helicase Q1

1

8

High-throughput

0.479

High

824040

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

10

High-throughput

0.479

High

877739

FOXA1
Hepatocyte nuclear factor 3-alpha

1

2

High-throughput

0.479

High

908594

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

917316

H4
Histone H4

1

9

High-throughput

0.479

High

921277

RBX1
E3 ubiquitin-protein ligase RBX1

1

1

High-throughput

0.479

High

969720

KIF23
Kinesin-like protein KIF23

1

18

High-throughput

0.479

High

998739

EP300
Histone acetyltransferase p300

1

7

High-throughput

0.479

High

1016186

FOXO1
Forkhead box protein O1

1

4

High-throughput

0.479

High

1018964

TP53B
TP53-binding protein 1

1

8

High-throughput

0.479

High

1026421

RFA4
Replication protein A 30 kDa subunit

1

13

High-throughput

0.479

High

1035773

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

1043364

CUL4B
Cullin-4B

1

20

High-throughput

0.479

High

1055378

DHX8
ATP-dependent RNA helicase DHX8

1

6

High-throughput

0.479

High

1063804

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

1066155

KIF14
Kinesin-like protein KIF14

1

9

High-throughput

0.479

High

1073508

FSCN1
Fascin

1

1

High-throughput

0.479

High

1073513

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

1

14

High-throughput

0.479

High

1073515

Q6ICH2
Apolipoprotein B mRNA editing enzyme catalytic subunit 3D

1

18

High-throughput

0.479

High

1073521

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

8

High-throughput

0.479

High

1073523

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.479

High

1073524

ZCH18
Zinc finger CCCH domain-containing protein 18

1

13

High-throughput

0.479

High

1073525

DHX40
Probable ATP-dependent RNA helicase DHX40

1

6

High-throughput

0.479

High

1073526

SMC5
Structural maintenance of chromosomes protein 5

1

9

High-throughput

0.479

High

1073527

SLX4
Structure-specific endonuclease subunit SLX4

1

4

High-throughput

0.479

High

1073528

SRRM1
Serine/arginine repetitive matrix protein 1

1

8

High-throughput

0.479

High

1073530

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

5

High-throughput

0.479

High

1073531

ZFP41
Zinc finger protein 41 homolog

1

4

High-throughput

0.479

High

1073533

NUP43
Nucleoporin Nup43

1

5

High-throughput

0.479

High

1073535

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

5

High-throughput

0.479

High

1073538

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1073540

FUBP1
Far upstream element-binding protein 1

1

20

High-throughput

0.479

High

1073543

CHM4C
Charged multivesicular body protein 4c

1

10

High-throughput

0.479

High

1073551

ANM1
Protein arginine N-methyltransferase 1

1

8

High-throughput

0.479

High

1073554

DDX23
Probable ATP-dependent RNA helicase DDX23

1

8

High-throughput

0.479

High

1073556

FACD2
Fanconi anemia group D2 protein

1

11

High-throughput

0.479

High

1073565

RAD18
E3 ubiquitin-protein ligase RAD18

1

1

High-throughput

0.479

High

1073567

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1073568

UBQL2
Ubiquilin-2

1

3

High-throughput

0.479

High

1073572

FBW1A
F-box/WD repeat-containing protein 1A

1

10

High-throughput

0.479

High

329741

AGR2
Anterior gradient protein 2 homolog

1

4

High-throughput

0.470

High

456874

FURIN
Furin

1

1

High-throughput

0.470

High

1073549

STAC
SH3 and cysteine-rich domain-containing protein

1

8

High-throughput

0.470

High

1073557

ACE2
Angiotensin-converting enzyme 2

1

3

High-throughput

0.470

High

364288

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.458

High

551529

TFE2
Transcription factor E2-alpha

1

0

High-throughput

0.458

High

1026279

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.458

High

988899

FMR1
Fragile X messenger ribonucleoprotein 1

1

8

High-throughput

0.457

High

1018327

MERTK
Tyrosine-protein kinase Mer

1

14

High-throughput

0.457

High

402052

JUN
Transcription factor Jun

1

7

High-throughput

0.445

High

487460

ANDR
Androgen receptor

1

20

Small-scale

0.445

High

497072

TAU
Microtubule-associated protein tau

1

13

High-throughput

0.445

High

1073510

NCBP3
Nuclear cap-binding protein subunit 3

1

5

High-throughput

0.445

High

1073511

ODFP2
Outer dense fiber protein 2

1

2

High-throughput

0.445

High

1073522

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

2

High-throughput

0.445

High

1073541

ABC3D
DNA dC->dU-editing enzyme APOBEC-3D

1

18

High-throughput

0.445

High

1073569

DDX41
Probable ATP-dependent RNA helicase DDX41

1

4

High-throughput

0.445

High

155364

NRP1
Neuropilin-1

1

1

High-throughput

0.437

High

255811

OBSL1
Obscurin-like protein 1

1

7

High-throughput

0.437

High

384893

NTRK1
High affinity nerve growth factor receptor

1

13

High-throughput

0.437

High

726218

BASI
Basigin

1

6

High-throughput

0.437

High

897739

ABCE1
ATP-binding cassette sub-family E member 1

1

1

High-throughput

0.437

High

1061419

CUL7
Cullin-7

1

8

High-throughput

0.437

High

1073514

A16L1
Autophagy-related protein 16-1

1

12

High-throughput

0.437

High

1073518

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1073537

CLC4D
C-type lectin domain family 4 member D

1

2

High-throughput

0.437

High

1073562

PKHA4
Pleckstrin homology domain-containing family A member 4

1

19

High-throughput

0.437

High

1073571

CLC4E
C-type lectin domain family 4 member E

1

2

High-throughput

0.437

High

831349

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.408

High

240009

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.407

High

1047093

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

8

High-throughput

0.407

High

1073545

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

0

High-throughput

0.279

Low

750579

VKGC
Vitamin K-dependent gamma-carboxylase

1

0

High-throughput

0.269

Low

792709

EAA1
Excitatory amino acid transporter 1

1

0

High-throughput

0.269

Low

326989

ABHGA
Phosphatidylserine lipase ABHD16A

1

0

Small-scale

0.265

Low

1073506

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.265

Low

648773

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.249

Low

1073555

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024