Protein: NU214
Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN)

Gene: NU214, NUP214
Organism: Homo sapiens
Interactions: 171
UniProt ID: P35658

Gene Ontology (top 5):
GO:0005049 - nuclear export signal receptor activity
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

162448

XPO1
Exportin-1

5

20

Small-scale

0.918

High

727254

IMB1
Importin subunit beta-1

3

20

Small-scale

0.861

High

727326

NXF1
Nuclear RNA export factor 1

10

10

Small-scale

0.754

High

727307

NUP88
Nuclear pore complex protein Nup88

7

2

Small-scale

0.747

High

727210

NUP62
Nuclear pore glycoprotein p62

5

20

Small-scale

0.716

High

727236

RAN
GTP-binding nuclear protein Ran

4

9

Small-scale

0.699

High

727332

G3BP2
Ras GTPase-activating protein-binding protein 2

4

6

High-throughput

0.697

High

727232

NU107
Nuclear pore complex protein Nup107

4

7

Small-scale

0.686

High

727239

RAE1L
mRNA export factor RAE1

4

20

Small-scale

0.686

High

727331

DD19B
ATP-dependent RNA helicase DDX19B

3

11

Small-scale

0.679

High

727313

NXF2
Nuclear RNA export factor 2

3

10

Small-scale

0.670

High

727324

DD19A
ATP-dependent RNA helicase DDX19A

3

11

High-throughput

0.667

High

727224

RBP2
E3 SUMO-protein ligase RanBP2

3

6

Small-scale

0.656

High

727291

NUP35
Nucleoporin NUP35

3

6

Small-scale

0.640

High

727226

FXR2
RNA-binding protein FXR2

2

12

High-throughput

0.628

High

727246

G3BP1
Ras GTPase-activating protein-binding protein 1

2

6

High-throughput

0.621

High

727228

XPO2
Exportin-2

1

11

Small-scale

0.618

High

727300

TNPO1
Transportin-1

1

20

Small-scale

0.618

High

727318

XPO5
Exportin-5

1

17

Small-scale

0.618

High

727340

TNPO3
Transportin-3

1

19

Small-scale

0.618

High

727223

NU153
Nuclear pore complex protein Nup153

2

19

Small-scale

0.611

High

727227

NUP98
Nuclear pore complex protein Nup98-Nup96

2

20

Small-scale

0.611

High

727251

CUL3
Cullin-3

2

7

High-throughput

0.611

High

727269

NU188
Nucleoporin NUP188

2

1

Small-scale

0.611

High

727286

NUP93
Nuclear pore complex protein Nup93

2

5

Small-scale

0.611

High

727310

NUP58
Nucleoporin p58/p45

2

15

Small-scale

0.611

High

127197

IPO5
Importin-5

2

19

Small-scale

0.595

High

226688

PRKN
E3 ubiquitin-protein ligase parkin

2

20

High-throughput

0.584

High

273705

NU155
Nuclear pore complex protein Nup155

2

9

Small-scale

0.584

High

727213

CCNF
Cyclin-F

2

6

High-throughput

0.584

High

727231

HDAC4
Histone deacetylase 4

2

20

Small-scale

0.584

High

727268

GLE1
mRNA export factor GLE1

2

15

Small-scale

0.584

High

727311

NUP85
Nuclear pore complex protein Nup85

2

6

Small-scale

0.584

High

727341

EMIL1
EMILIN-1

2

9

High-throughput

0.574

High

644233

TTP
mRNA decay activator protein ZFP36

1

2

Small-scale

0.573

High

727262

ITSN1
Intersectin-1

2

16

High-throughput

0.571

High

727267

PKHG6
Pleckstrin homology domain-containing family G member 6

2

8

High-throughput

0.571

High

727339

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

2

9

High-throughput

0.571

High

727240

SMAD3
Mothers against decapentaplegic homolog 3

1

8

Small-scale

0.561

High

727247

SMAD4
Mothers against decapentaplegic homolog 4

1

9

Small-scale

0.561

High

727260

SMAD2
Mothers against decapentaplegic homolog 2

1

8

Small-scale

0.561

High

626063

APC
Adenomatous polyposis coli protein

1

19

High-throughput

0.541

High

174675

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

13

High-throughput

0.536

High

506533

BCR
Breakpoint cluster region protein

1

11

High-throughput

0.536

High

675123

CLIP1
CAP-Gly domain-containing linker protein 1

1

11

High-throughput

0.536

High

727216

TEC
Tyrosine-protein kinase Tec

1

11

High-throughput

0.536

High

727217

KSYK
Tyrosine-protein kinase SYK

1

20

High-throughput

0.536

High

727218

RANG
Ran-specific GTPase-activating protein

1

12

High-throughput

0.536

High

727220

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.536

High

727221

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.536

High

727237

UBC9
SUMO-conjugating enzyme UBC9

1

7

High-throughput

0.536

High

727238

TBB4B
Tubulin beta-4B chain

1

2

High-throughput

0.536

High

727250

CUL2
Cullin-2

1

7

High-throughput

0.536

High

727253

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

14

High-throughput

0.536

High

727255

NUMA1
Nuclear mitotic apparatus protein 1

1

9

High-throughput

0.536

High

727259

MARE1
Microtubule-associated protein RP/EB family member 1

1

6

High-throughput

0.536

High

727292

UHMK1
Serine/threonine-protein kinase Kist

1

7

High-throughput

0.536

High

727293

NEK7
Serine/threonine-protein kinase Nek7

1

10

High-throughput

0.536

High

727297

DNJC9
DnaJ homolog subfamily C member 9

1

7

High-throughput

0.536

High

727302

SEH1
Nucleoporin SEH1

1

20

High-throughput

0.536

High

727304

AURKB
Aurora kinase B

1

9

High-throughput

0.536

High

727309

MKNK1
MAP kinase-interacting serine/threonine-protein kinase 1

1

7

High-throughput

0.536

High

727319

NXT2
NTF2-related export protein 2

1

7

High-throughput

0.536

High

727323

LATS2
Serine/threonine-protein kinase LATS2

1

5

High-throughput

0.536

High

727335

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

2

High-throughput

0.536

High

727209

NU214
Nuclear pore complex protein Nup214

1

15

Small-scale

0.501

High

727233

SUMO2
Small ubiquitin-related modifier 2

1

7

High-throughput

0.501

High

727308

TS101
Tumor susceptibility gene 101 protein

1

2

High-throughput

0.501

High

397012

PAI2
Plasminogen activator inhibitor 2

1

1

High-throughput

0.489

High

727305

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.489

High

727306

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.489

High

727328

CHRD1
Cysteine and histidine-rich domain-containing protein 1

1

1

High-throughput

0.489

High

727342

RPKL1
Ribosomal protein S6 kinase-like 1

1

9

High-throughput

0.489

High

56514

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

1

5

High-throughput

0.479

High

131388

IMA4
Importin subunit alpha-4

1

7

Small-scale

0.479

High

150887

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

14

High-throughput

0.479

High

215201

STRN
Striatin

1

20

Small-scale

0.479

High

232022

KDM1A
Lysine-specific histone demethylase 1A

1

8

High-throughput

0.479

High

727317

RANB3
Ran-binding protein 3

1

12

Small-scale

0.479

High

727320

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

Small-scale

0.479

High

727321

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

10

High-throughput

0.479

High

727322

FBX6
F-box only protein 6

1

2

High-throughput

0.479

High

727325

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

1

Small-scale

0.479

High

727327

ZRAN1
Ubiquitin thioesterase ZRANB1

1

14

High-throughput

0.479

High

727329

HDAC9
Histone deacetylase 9

1

20

Small-scale

0.479

High

727330

NUP50
Nuclear pore complex protein Nup50

1

11

Small-scale

0.479

High

232795

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

7

High-throughput

0.479

High

233251

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

255554

OBSL1
Obscurin-like protein 1

1

14

High-throughput

0.479

High

346095

MYC
Myc proto-oncogene protein

1

19

High-throughput

0.479

High

359712

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

15

High-throughput

0.479

High

518828

TPR
Nucleoprotein TPR

1

19

Small-scale

0.479

High

552086

RFA2
Replication protein A 32 kDa subunit

1

11

High-throughput

0.479

High

569297

CEBPB
CCAAT/enhancer-binding protein beta

1

18

High-throughput

0.479

High

594282

MX2
Interferon-induced GTP-binding protein Mx2

1

6

Small-scale

0.479

High

622559

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

1

High-throughput

0.479

High

650517

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

9

High-throughput

0.479

High

684454

STIP1
Stress-induced-phosphoprotein 1

1

8

High-throughput

0.479

High

716821

CTNB1
Catenin beta-1

1

13

High-throughput

0.479

High

719826

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.479

High

727211

SYUA
Alpha-synuclein

1

2

High-throughput

0.479

High

727212

BRCA1
Breast cancer type 1 susceptibility protein

1

10

High-throughput

0.479

High

727214

ETV6
Transcription factor ETV6

1

17

High-throughput

0.479

High

727215

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

1

Small-scale

0.479

High

727219

RAGP1
Ran GTPase-activating protein 1

1

3

Small-scale

0.479

High

727222

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

20

High-throughput

0.479

High

727225

CDK9
Cyclin-dependent kinase 9

1

12

High-throughput

0.479

High

727229

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.479

High

727230

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

13

Small-scale

0.479

High

727234

NTF2
Nuclear transport factor 2

1

7

High-throughput

0.479

High

727235

H4
Histone H4

1

9

High-throughput

0.479

High

727242

KMT2A
Histone-lysine N-methyltransferase 2A

1

20

Small-scale

0.479

High

727243

NU160
Nuclear pore complex protein Nup160

1

3

Small-scale

0.479

High

727244

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

1

High-throughput

0.479

High

727245

RFA4
Replication protein A 30 kDa subunit

1

11

High-throughput

0.479

High

727248

BIRC3
Baculoviral IAP repeat-containing protein 3

1

10

High-throughput

0.479

High

727249

HDAC1
Histone deacetylase 1

1

13

High-throughput

0.479

High

727252

CUL4B
Cullin-4B

1

7

High-throughput

0.479

High

727256

CUL7
Cullin-7

1

9

High-throughput

0.479

High

727258

SUZ12
Polycomb protein SUZ12

1

2

High-throughput

0.479

High

727261

SMAD1
Mothers against decapentaplegic homolog 1

1

8

Small-scale

0.479

High

727263

EZH2
Histone-lysine N-methyltransferase EZH2

1

17

High-throughput

0.479

High

727264

E2F4
Transcription factor E2F4

1

7

High-throughput

0.479

High

727265

IF16
Gamma-interferon-inducible protein 16

1

6

High-throughput

0.479

High

727266

CL16A
Protein CLEC16A

1

2

High-throughput

0.479

High

727275

SYNE3
Nesprin-3

1

5

High-throughput

0.479

High

727278

NUP54
Nucleoporin p54

1

18

Small-scale

0.479

High

727280

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

13

High-throughput

0.479

High

727281

SLN11
Schlafen family member 11

1

2

High-throughput

0.479

High

727282

NAA40
N-alpha-acetyltransferase 40

1

8

High-throughput

0.479

High

727283

TAXB1
Tax1-binding protein 1

1

9

High-throughput

0.479

High

727284

SMC5
Structural maintenance of chromosomes protein 5

1

12

High-throughput

0.479

High

727285

SLX4
Structure-specific endonuclease subunit SLX4

1

17

High-throughput

0.479

High

727287

SIR6
NAD-dependent protein deacylase sirtuin-6

1

10

High-throughput

0.479

High

727288

FBX22
F-box only protein 22

1

3

High-throughput

0.479

High

727289

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.479

High

727290

NUP37
Nucleoporin Nup37

1

20

Small-scale

0.479

High

727296

NU133
Nuclear pore complex protein Nup133

1

4

Small-scale

0.479

High

727298

NU205
Nuclear pore complex protein Nup205

1

8

Small-scale

0.479

High

727299

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

727301

PF21A
PHD finger protein 21A

1

16

High-throughput

0.479

High

727303

RNF31
E3 ubiquitin-protein ligase RNF31

1

13

High-throughput

0.479

High

727334

HDAC5
Histone deacetylase 5

1

19

Small-scale

0.479

High

727338

TRRAP
Transformation/transcription domain-associated protein

1

8

High-throughput

0.479

High

181166

NUP42
Nucleoporin NUP42

1

0

Small-scale

0.460

High

200864

CTIF
CBP80/20-dependent translation initiation factor

1

0

High-throughput

0.458

High

727241

SET
Protein SET

1

0

Small-scale

0.458

High

727271

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

727295

PO210
Nuclear pore membrane glycoprotein 210

1

0

Small-scale

0.458

High

727312

NDEL1
Nuclear distribution protein nudE-like 1

1

13

High-throughput

0.457

High

727314

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

17

High-throughput

0.445

High

727315

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

17

High-throughput

0.445

High

727333

DICER
Endoribonuclease Dicer

1

6

Small-scale

0.445

High

384391

NTRK1
High affinity nerve growth factor receptor

1

10

High-throughput

0.437

High

521765

CADH1
Cadherin-1

1

2

High-throughput

0.437

High

530472

ITA4
Integrin alpha-4

1

4

High-throughput

0.437

High

727257

HAPR1
HUWE1-associated protein modifying stress responses 1

1

3

Small-scale

0.437

High

727270

RHDF2
Inactive rhomboid protein 2

1

1

High-throughput

0.437

High

727272

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

727274

DPPA3
Developmental pluripotency-associated protein 3

1

1

High-throughput

0.437

High

727276

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

727277

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

9

Small-scale

0.437

High

727279

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

16

High-throughput

0.437

High

727294

RHBL4
Rhomboid-related protein 4

1

1

High-throughput

0.437

High

727316

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.437

High

727336

T3JAM
TRAF3-interacting JNK-activating modulator

1

10

Small-scale

0.437

High

727337

CLC11
C-type lectin domain family 11 member A

1

1

High-throughput

0.437

High

353648

IGHG1
Immunoglobulin heavy constant gamma 1

1

2

High-throughput

0.407

High

581491

VCAM1
Vascular cell adhesion protein 1

1

3

High-throughput

0.407

High

727273

CLC4G
C-type lectin domain family 4 member G

1

0

High-throughput

0.265

Low


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Last updated: 15 Jul 2024