Protein: RBBP6
E3 ubiquitin-protein ligase RBBP6 (EC 2.3.2.27) (Proliferation potential-related protein) (Protein P2P-R) (RING-type E3 ubiquitin transferase RBBP6) (Retinoblastoma-binding Q protein 1) (RBQ-1) (Retinoblastoma-binding protein 6) (p53-associated cellular protein of testis)

Gene: RBBP6
Organism: Homo sapiens
Interactions: 200
UniProt ID: Q7Z6E9

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0003723 - RNA binding
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005694 - chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

833911

CLK2
Dual specificity protein kinase CLK2

4

10

High-throughput

0.699

High

834072

CLK3
Dual specificity protein kinase CLK3

4

10

High-throughput

0.699

High

942757

SRPK2
SRSF protein kinase 2

3

18

High-throughput

0.667

High

1040353

TRA2A
Transformer-2 protein homolog alpha

3

7

High-throughput

0.667

High

1084509

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

3

14

High-throughput

0.667

High

1191685

ZCH18
Zinc finger CCCH domain-containing protein 18

3

17

High-throughput

0.667

High

1191720

PININ
Pinin

3

1

High-throughput

0.667

High

930279

UBC9
SUMO-conjugating enzyme UBC9

1

4

High-throughput

0.656

High

962842

MDM2
E3 ubiquitin-protein ligase Mdm2

3

2

Small-scale

0.656

High

1084316

SRSF7
Serine/arginine-rich splicing factor 7

2

16

High-throughput

0.644

High

1191691

ZBT38
Zinc finger and BTB domain-containing protein 38

2

1

Small-scale

0.636

High

369909

ESR1
Estrogen receptor

3

20

Small-scale

0.633

High

924667

GRB2
Growth factor receptor-bound protein 2

2

12

High-throughput

0.633

High

814640

CDX1
Homeobox protein CDX-1

2

3

High-throughput

0.628

High

1191697

TP4AP
Short transient receptor potential channel 4-associated protein

2

1

High-throughput

0.628

High

1191722

ZN576
Zinc finger protein 576

2

4

High-throughput

0.628

High

908752

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.618

High

1191749

PRP19
Pre-mRNA-processing factor 19

1

13

High-throughput

0.618

High

1191715

RBM4
RNA-binding protein 4

2

10

Small-scale

0.611

High

813087

CAZA2
F-actin-capping protein subunit alpha-2

2

3

High-throughput

0.600

High

931243

YBOX1
Y-box-binding protein 1

1

2

Small-scale

0.586

High

127817

SAP18
Histone deacetylase complex subunit SAP18

2

0

High-throughput

0.585

High

244615

BRD4
Bromodomain-containing protein 4

2

12

High-throughput

0.584

High

1014159

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

2

3

Small-scale

0.584

High

1078521

NCOA1
Nuclear receptor coactivator 1

2

1

Small-scale

0.584

High

387007

P53
Cellular tumor antigen p53

1

7

Small-scale

0.561

High

714282

HSP74
Heat shock 70 kDa protein 4

1

10

Small-scale

0.561

High

1191725

NEK6
Serine/threonine-protein kinase Nek6

1

6

Small-scale

0.549

High

414326

RB
Retinoblastoma-associated protein

1

0

Small-scale

0.537

High

1191713

FAP24
Fanconi anemia core complex-associated protein 24

1

0

High-throughput

0.536

High

180360

MAGB2
Melanoma-associated antigen B2

1

4

High-throughput

0.536

High

432788

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

10

High-throughput

0.536

High

433400

YES
Tyrosine-protein kinase Yes

1

1

High-throughput

0.536

High

446688

SNRPA
U1 small nuclear ribonucleoprotein A

1

10

High-throughput

0.536

High

474827

POTEI
POTE ankyrin domain family member I

1

9

High-throughput

0.536

High

508593

TOP1
DNA topoisomerase 1

1

2

High-throughput

0.536

High

539030

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

2

High-throughput

0.536

High

824648

MAPK2
MAP kinase-activated protein kinase 2

1

3

High-throughput

0.536

High

952014

SRSF3
Serine/arginine-rich splicing factor 3

1

20

High-throughput

0.536

High

993755

SRSF4
Serine/arginine-rich splicing factor 4

1

15

High-throughput

0.536

High

996739

SSRP1
FACT complex subunit SSRP1

1

12

High-throughput

0.536

High

1028977

SRSF6
Serine/arginine-rich splicing factor 6

1

16

High-throughput

0.536

High

1041067

CUL1
Cullin-1

1

10

High-throughput

0.536

High

1070530

RNPS1
RNA-binding protein with serine-rich domain 1

1

10

High-throughput

0.536

High

1074157

SF3A1
Splicing factor 3A subunit 1

1

9

High-throughput

0.536

High

1092850

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

12

High-throughput

0.536

High

1191688

ERF3B
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B

1

6

High-throughput

0.536

High

1191699

LAR4B
La-related protein 4B

1

5

High-throughput

0.536

High

1191701

EZH1
Histone-lysine N-methyltransferase EZH1

1

19

High-throughput

0.536

High

1191705

PABP5
Polyadenylate-binding protein 5

1

11

High-throughput

0.536

High

1191712

H2AJ
Histone H2A.J

1

9

High-throughput

0.536

High

1191741

PURG
Purine-rich element-binding protein gamma

1

1

High-throughput

0.536

High

448718

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

1191694

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.513

High

1191746

ZN346
Zinc finger protein 346

1

0

High-throughput

0.513

High

267511

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

1

2

High-throughput

0.508

High

278121

PIAS1
E3 SUMO-protein ligase PIAS1

1

4

High-throughput

0.508

High

313554

ZFYV9
Zinc finger FYVE domain-containing protein 9

1

2

High-throughput

0.508

High

532567

TCTP
Translationally-controlled tumor protein

1

1

High-throughput

0.508

High

855807

VAV2
Guanine nucleotide exchange factor VAV2

1

13

High-throughput

0.508

High

1084823

SMN
Survival motor neuron protein

1

1

High-throughput

0.508

High

1191708

RCC1L
RCC1-like G exchanging factor-like protein

1

4

High-throughput

0.508

High

1191740

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

2

High-throughput

0.508

High

833761

CLK1
Dual specificity protein kinase CLK1

1

10

High-throughput

0.501

High

1191742

CPSF3
Cleavage and polyadenylation specificity factor subunit 3

1

5

Small-scale

0.501

High

835195

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

0

High-throughput

0.493

High

1191702

ARRD3
Arrestin domain-containing protein 3

1

13

High-throughput

0.489

High

1191706

ERLEC
Endoplasmic reticulum lectin 1

1

1

High-throughput

0.489

High

1191747

ANR50
Ankyrin repeat domain-containing protein 50

1

15

High-throughput

0.489

High

543036

GLNA
Glutamine synthetase

1

0

High-throughput

0.486

High

1191726

ACO13
Acyl-coenzyme A thioesterase 13

1

0

High-throughput

0.486

High

1191752

FBX7
F-box only protein 7

1

0

High-throughput

0.486

High

159236

CSKP
Peripheral plasma membrane protein CASK

1

4

High-throughput

0.481

High

542034

ETS1
Protein C-ets-1

1

6

Small-scale

0.481

High

910478

RS14
Small ribosomal subunit protein uS11

1

1

Small-scale

0.481

High

1191703

APC16
Anaphase-promoting complex subunit 16

1

1

Small-scale

0.481

High

1191729

4ET
Eukaryotic translation initiation factor 4E transporter

1

1

High-throughput

0.481

High

122851

MEN1
Menin

1

5

High-throughput

0.479

High

148996

CTRO
Citron Rho-interacting kinase

1

11

High-throughput

0.479

High

158615

RGS12
Regulator of G-protein signaling 12

1

3

Small-scale

0.479

High

182809

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.479

High

210100

PRC1
Protein regulator of cytokinesis 1

1

4

High-throughput

0.479

High

214974

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

1

High-throughput

0.479

High

268151

EED
Polycomb protein EED

1

19

High-throughput

0.479

High

297641

RHBT1
Rho-related BTB domain-containing protein 1

1

8

High-throughput

0.479

High

301903

TRI37
E3 ubiquitin-protein ligase TRIM37

1

10

High-throughput

0.479

High

308837

KI20A
Kinesin-like protein KIF20A

1

17

High-throughput

0.479

High

317840

CPSF4
Cleavage and polyadenylation specificity factor subunit 4

1

6

Small-scale

0.479

High

347186

MYC
Myc proto-oncogene protein

1

14

High-throughput

0.479

High

379555

MYCN
N-myc proto-oncogene protein

1

13

High-throughput

0.479

High

430995

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

3

High-throughput

0.479

High

442276

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

15

High-throughput

0.479

High

517336

PCNA
Proliferating cell nuclear antigen

1

3

High-throughput

0.479

High

523848

XRCC6
X-ray repair cross-complementing protein 6

1

6

High-throughput

0.479

High

553066

RFA2
Replication protein A 32 kDa subunit

1

9

High-throughput

0.479

High

577662

SON
Protein SON

1

15

High-throughput

0.479

High

639770

IKBA
NF-kappa-B inhibitor alpha

1

20

Small-scale

0.479

High

651569

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

9

High-throughput

0.479

High

703402

CSTF2
Cleavage stimulation factor subunit 2

1

10

Small-scale

0.479

High

720807

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.479

High

757665

IF4A3
Eukaryotic initiation factor 4A-III

1

8

High-throughput

0.479

High

779666

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

808734

YAP1
Transcriptional coactivator YAP1

1

16

High-throughput

0.479

High

813582

CAPZB
F-actin-capping protein subunit beta

1

4

High-throughput

0.479

High

824146

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

7

High-throughput

0.479

High

853933

NCBP2
Nuclear cap-binding protein subunit 2

1

11

High-throughput

0.479

High

858645

PPP5
Serine/threonine-protein phosphatase 5

1

19

High-throughput

0.479

High

882398

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

16

High-throughput

0.479

High

917508

H4
Histone H4

1

10

High-throughput

0.479

High

932231

ACTC
Actin, alpha cardiac muscle 1

1

8

High-throughput

0.479

High

941105

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.479

High

967250

EWS
RNA-binding protein EWS

1

8

High-throughput

0.479

High

977900

HSF2
Heat shock factor protein 2

1

1

High-throughput

0.479

High

980799

TLE3
Transducin-like enhancer protein 3

1

16

High-throughput

0.479

High

988975

FMR1
Fragile X messenger ribonucleoprotein 1

1

9

High-throughput

0.479

High

997293

MZT1
Mitotic-spindle organizing protein 1

1

1

High-throughput

0.479

High

998844

EP300
Histone acetyltransferase p300

1

14

High-throughput

0.479

High

1016207

FOXO1
Forkhead box protein O1

1

9

High-throughput

0.479

High

1016807

TFCP2
Alpha-globin transcription factor CP2

1

2

High-throughput

0.479

High

1022291

CSTF3
Cleavage stimulation factor subunit 3

1

4

Small-scale

0.479

High

1027090

CBX3
Chromobox protein homolog 3

1

10

High-throughput

0.479

High

1034004

PPIG
Peptidyl-prolyl cis-trans isomerase G

1

4

High-throughput

0.479

High

1041918

CUL3
Cullin-3

1

10

High-throughput

0.479

High

1055410

DHX8
ATP-dependent RNA helicase DHX8

1

5

High-throughput

0.479

High

1056068

NBR1
Next to BRCA1 gene 1 protein

1

1

High-throughput

0.479

High

1059701

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

9

High-throughput

0.479

High

1062165

HAPR1
HUWE1-associated protein modifying stress responses 1

1

1

High-throughput

0.479

High

1063914

TNIP1
TNFAIP3-interacting protein 1

1

19

High-throughput

0.479

High

1067027

BRD3
Bromodomain-containing protein 3

1

14

High-throughput

0.479

High

1071919

PCBP1
Poly(rC)-binding protein 1

1

9

High-throughput

0.479

High

1080080

EZH2
Histone-lysine N-methyltransferase EZH2

1

19

High-throughput

0.479

High

1146565

A16L1
Autophagy-related protein 16-1

1

17

High-throughput

0.479

High

1158543

L2GL2
LLGL scribble cell polarity complex component 2

1

4

High-throughput

0.479

High

1159170

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

High-throughput

0.479

High

1170598

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.479

High

1188496

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

11

High-throughput

0.479

High

1191682

SLN11
Schlafen family member 11

1

1

High-throughput

0.479

High

1191683

NAA40
N-alpha-acetyltransferase 40

1

5

High-throughput

0.479

High

1191686

DHX40
Probable ATP-dependent RNA helicase DHX40

1

5

High-throughput

0.479

High

1191687

SMC5
Structural maintenance of chromosomes protein 5

1

11

High-throughput

0.479

High

1191689

KMT2E
Inactive histone-lysine N-methyltransferase 2E

1

16

Small-scale

0.479

High

1191690

FBXW8
F-box/WD repeat-containing protein 8

1

10

High-throughput

0.479

High

1191692

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.479

High

1191695

SP7
Transcription factor Sp7

1

12

High-throughput

0.479

High

1191696

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

1191698

DCAF4
DDB1- and CUL4-associated factor 4

1

1

High-throughput

0.479

High

1191700

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1191704

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

18

High-throughput

0.479

High

1191707

THOC1
THO complex subunit 1

1

1

High-throughput

0.479

High

1191709

YTDC1
YTH domain-containing protein 1

1

5

High-throughput

0.479

High

1191710

MMS19
MMS19 nucleotide excision repair protein homolog

1

1

High-throughput

0.479

High

1191711

CDC5L
Cell division cycle 5-like protein

1

7

High-throughput

0.479

High

1191714

DDX23
Probable ATP-dependent RNA helicase DDX23

1

3

High-throughput

0.479

High

1191716

FACD2
Fanconi anemia group D2 protein

1

3

High-throughput

0.479

High

1191717

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

13

High-throughput

0.479

High

1191718

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

7

High-throughput

0.479

High

1191723

CLK4
Dual specificity protein kinase CLK4

1

10

High-throughput

0.479

High

1191724

RC3H2
Roquin-2

1

12

High-throughput

0.479

High

1191728

ANLN
Anillin

1

8

High-throughput

0.479

High

1191730

RAD18
E3 ubiquitin-protein ligase RAD18

1

2

High-throughput

0.479

High

1191731

NLE1
Notchless protein homolog 1

1

6

High-throughput

0.479

High

1191732

NALP2
NACHT, LRR and PYD domains-containing protein 2

1

1

High-throughput

0.479

High

1191733

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

5

High-throughput

0.479

High

1191734

BCLF1
Bcl-2-associated transcription factor 1

1

13

High-throughput

0.479

High

1191735

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

5

Small-scale

0.479

High

1191736

HECW2
E3 ubiquitin-protein ligase HECW2

1

7

High-throughput

0.479

High

1191738

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

1191739

TBK1
Serine/threonine-protein kinase TBK1

1

4

High-throughput

0.479

High

1191743

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

13

High-throughput

0.479

High

1191748

HECD1
E3 ubiquitin-protein ligase HECTD1

1

16

High-throughput

0.479

High

1191750

SRRM2
Serine/arginine repetitive matrix protein 2

1

17

High-throughput

0.479

High

1191751

TR150
Thyroid hormone receptor-associated protein 3

1

16

High-throughput

0.479

High

341214

HPT
Haptoglobin

1

1

High-throughput

0.464

High

426779

ASGR1
Asialoglycoprotein receptor 1

1

1

High-throughput

0.464

High

1191737

TFP11
Tuftelin-interacting protein 11

1

0

High-throughput

0.460

High

1191744

AGO2
Protein argonaute-2

1

0

Small-scale

0.460

High

547573

FOLR1
Folate receptor alpha

1

0

High-throughput

0.458

High

615777

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.458

High

879532

BID
BH3-interacting domain death agonist

1

0

Small-scale

0.458

High

1191684

SERC5
Serine incorporator 5

1

0

Small-scale

0.458

High

1191693

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

402204

JUN
Transcription factor Jun

1

5

High-throughput

0.445

High

1130262

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

Small-scale

0.445

High

1191719

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

16

High-throughput

0.445

High

1191721

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

16

High-throughput

0.445

High

887888

CD81
CD81 antigen

1

1

Small-scale

0.439

High

181432

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.438

High

282942

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

16

High-throughput

0.437

High

1159974

KLC3
Kinesin light chain 3

1

6

High-throughput

0.437

High

1191745

NUP50
Nuclear pore complex protein Nup50

1

3

High-throughput

0.437

High

200613

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.426

High

281718

WFS1
Wolframin

1

0

High-throughput

0.268

Low

341387

PLMN
Plasminogen

1

0

High-throughput

0.265

Low

362636

APOH
Beta-2-glycoprotein 1

1

0

High-throughput

0.265

Low

1191753

NDUB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

1

0

High-throughput

0.265

Low

264507

LRCH4
Leucine-rich repeat and calponin homology domain-containing protein 4

1

0

Small-scale

0.251

Low

363389

RET4
Retinol-binding protein 4

1

0

High-throughput

0.251

Low

489600

OSTP
Osteopontin

1

0

Small-scale

0.251

Low

885931

EVA1C
Protein eva-1 homolog C

1

0

Small-scale

0.251

Low

1191727

LUC7L
Putative RNA-binding protein Luc7-like 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024