Protein: THOC6
THO complex subunit 6 homolog (Functional spliceosome-associated protein 35) (fSAP35) (WD repeat-containing protein 58)

Gene: THOC6
Organism: Homo sapiens
Interactions: 70
UniProt ID: Q86W42

Gene Ontology (top 5):
GO:0000346 - transcription export complex
GO:0000347 - THO complex
GO:0000445 - THO complex part of transcription export complex
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1202870

THOC2
THO complex subunit 2

4

20

Small-scale

0.881

High

1202879

THOC3
THO complex subunit 3

2

19

High-throughput

0.811

High

1202878

THOC1
THO complex subunit 1

5

3

Small-scale

0.716

High

1046093

DX39B
Spliceosome RNA helicase DDX39B

4

20

Small-scale

0.696

High

1202891

RHG26
Rho GTPase-activating protein 26

2

11

High-throughput

0.659

High

1120386

NCBP3
Nuclear cap-binding protein subunit 3

3

2

High-throughput

0.643

High

908766

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

9

High-throughput

0.618

High

1063477

SUZ12
Polycomb protein SUZ12

1

4

High-throughput

0.618

High

1202885

ANLN
Anillin

1

9

High-throughput

0.618

High

1045261

THOC5
THO complex subunit 5 homolog

2

2

Small-scale

0.611

High

1201090

THOC4
THO complex subunit 4

2

14

Small-scale

0.595

High

779681

CCNF
Cyclin-F

2

8

High-throughput

0.584

High

1202890

HECD1
E3 ubiquitin-protein ligase HECTD1

2

20

High-throughput

0.584

High

1153274

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.575

High

1202872

ESR2
Estrogen receptor beta

2

20

High-throughput

0.571

High

1146579

A16L1
Autophagy-related protein 16-1

1

19

High-throughput

0.553

High

1170646

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.553

High

1202883

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.553

High

212454

AAKB2
5'-AMP-activated protein kinase subunit beta-2

1

1

High-throughput

0.536

High

446696

SNRPA
U1 small nuclear ribonucleoprotein A

1

17

High-throughput

0.536

High

539040

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

7

High-throughput

0.536

High

996749

SSRP1
FACT complex subunit SSRP1

1

20

High-throughput

0.536

High

1074166

SF3A1
Splicing factor 3A subunit 1

1

10

High-throughput

0.536

High

1084517

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

18

High-throughput

0.536

High

1151829

THOC7
THO complex subunit 7 homolog

1

2

High-throughput

0.536

High

1202869

ABI1
Abl interactor 1

1

15

High-throughput

0.536

High

1202886

BCLF1
Bcl-2-associated transcription factor 1

1

13

High-throughput

0.536

High

780973

ID1
DNA-binding protein inhibitor ID-1

1

0

High-throughput

0.513

High

890726

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

4

High-throughput

0.501

High

122862

MEN1
Menin

1

5

High-throughput

0.479

High

282689

RNF8
E3 ubiquitin-protein ligase RNF8

1

15

High-throughput

0.479

High

319905

HERC2
E3 ubiquitin-protein ligase HERC2

1

7

High-throughput

0.479

High

322837

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

17

High-throughput

0.479

High

347217

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

374477

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

15

High-throughput

0.479

High

379573

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

442287

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

16

High-throughput

0.479

High

455614

PARP1
Poly [ADP-ribose] polymerase 1

1

16

High-throughput

0.479

High

553099

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

651604

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

720840

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.479

High

749642

BRCA1
Breast cancer type 1 susceptibility protein

1

13

High-throughput

0.479

High

801910

RECQ1
ATP-dependent DNA helicase Q1

1

20

High-throughput

0.479

High

917532

H4
Histone H4

1

10

High-throughput

0.479

High

959516

VIGLN
Vigilin

1

20

High-throughput

0.479

High

998112

NCBP1
Nuclear cap-binding protein subunit 1

1

3

Small-scale

0.479

High

1029594

TIF1B
Transcription intermediary factor 1-beta

1

20

High-throughput

0.479

High

1067032

BRD3
Bromodomain-containing protein 3

1

20

High-throughput

0.479

High

1201522

ZCH18
Zinc finger CCCH domain-containing protein 18

1

20

High-throughput

0.479

High

1202871

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

5

High-throughput

0.479

High

1202873

RBP56
TATA-binding protein-associated factor 2N

1

17

High-throughput

0.479

High

1202874

FUBP1
Far upstream element-binding protein 1

1

14

High-throughput

0.479

High

1202880

MMS19
MMS19 nucleotide excision repair protein homolog

1

1

High-throughput

0.479

High

1202881

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.479

High

1202884

NMRL1
NmrA-like family domain-containing protein 1

1

2

High-throughput

0.479

High

1202888

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

1202892

NUDC
Nuclear migration protein nudC

1

14

High-throughput

0.479

High

1202876

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1202887

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

402212

JUN
Transcription factor Jun

1

17

High-throughput

0.445

High

1124546

ODFP2
Outer dense fiber protein 2

1

14

High-throughput

0.445

High

1202889

DDX41
Probable ATP-dependent RNA helicase DDX41

1

14

High-throughput

0.445

High

297642

RHBT1
Rho-related BTB domain-containing protein 1

1

17

High-throughput

0.437

High

350305

RASK
GTPase KRas

1

12

High-throughput

0.437

High

1202877

CHM4C
Charged multivesicular body protein 4c

1

6

High-throughput

0.437

High

306224

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

9

High-throughput

0.407

High

891209

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

9

High-throughput

0.407

High

1134729

LITD1
LINE-1 type transposase domain-containing protein 1

1

1

High-throughput

0.407

High

1202882

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

9

High-throughput

0.407

High

1202875

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024