Protein: DDX42
ATP-dependent RNA helicase DDX42 (EC 3.6.4.13) (DEAD box protein 42) (RNA helicase-like protein) (RHELP) (RNA helicase-related protein) (RNAHP) (SF3b DEAD box protein) (Splicing factor 3B-associated 125 kDa protein) (SF3b125)

Gene: DDX42
Organism: Homo sapiens
Interactions: 187
UniProt ID: Q86XP3

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

195477

DHX15
ATP-dependent RNA helicase DHX15

2

9

High-throughput

0.767

High

1204691

DDX23
Probable ATP-dependent RNA helicase DDX23

2

16

High-throughput

0.754

High

295539

RECQ5
ATP-dependent DNA helicase Q5

1

17

High-throughput

0.698

High

941794

RBM6
RNA-binding protein 6

1

13

High-throughput

0.691

High

1204684

SPF45
Splicing factor 45

1

13

High-throughput

0.691

High

1073596

SF3B4
Splicing factor 3B subunit 4

3

9

High-throughput

0.664

High

726912

FUS
RNA-binding protein FUS

3

17

High-throughput

0.656

High

1073690

SF3A2
Splicing factor 3A subunit 2

3

4

Small-scale

0.656

High

448723

RU1C
U1 small nuclear ribonucleoprotein C

2

3

High-throughput

0.625

High

1074167

SF3A1
Splicing factor 3A subunit 1

2

3

High-throughput

0.625

High

640533

DDX6
Probable ATP-dependent RNA helicase DDX6

1

14

High-throughput

0.618

High

801911

RECQ1
ATP-dependent DNA helicase Q1

1

14

High-throughput

0.618

High

917536

H4
Histone H4

1

4

High-throughput

0.618

High

1018563

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

10

High-throughput

0.618

High

1055417

DHX8
ATP-dependent RNA helicase DHX8

1

8

High-throughput

0.618

High

1059712

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

10

High-throughput

0.618

High

1170662

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.618

High

1204703

DDX56
Probable ATP-dependent RNA helicase DDX56

1

15

High-throughput

0.618

High

1204710

RUVB2
RuvB-like 2

1

1

High-throughput

0.618

High

1204711

RUVB1
RuvB-like 1

1

1

High-throughput

0.618

High

268780

SF3B1
Splicing factor 3B subunit 1

2

3

Small-scale

0.611

High

508604

TOP1
DNA topoisomerase 1

2

3

High-throughput

0.611

High

796231

MAGAA
Melanoma-associated antigen 10

2

6

High-throughput

0.611

High

1054414

RBM39
RNA-binding protein 39

2

11

High-throughput

0.611

High

1084519

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

2

8

High-throughput

0.611

High

487570

ANDR
Androgen receptor

2

18

High-throughput

0.584

High

1184196

MEPCE
7SK snRNA methylphosphate capping enzyme

2

4

High-throughput

0.584

High

1204695

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

2

4

High-throughput

0.584

High

408642

KPCB
Protein kinase C beta type

2

3

High-throughput

0.571

High

1159741

RHGBA
Rho GTPase-activating protein 11A

2

5

High-throughput

0.571

High

1204669

SH2D3
SH2 domain-containing protein 3C

2

7

High-throughput

0.571

High

498304

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

0

High-throughput

0.547

High

155023

NDC80
Kinetochore protein NDC80 homolog

1

1

High-throughput

0.536

High

236794

CCNT1
Cyclin-T1

1

3

High-throughput

0.536

High

278835

DNJC8
DnaJ homolog subfamily C member 8

1

2

High-throughput

0.536

High

303340

HEXI1
Protein HEXIM1

1

4

High-throughput

0.536

High

313311

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

2

High-throughput

0.536

High

397045

PAI2
Plasminogen activator inhibitor 2

1

2

High-throughput

0.536

High

441326

RU2B
U2 small nuclear ribonucleoprotein B''

1

12

High-throughput

0.536

High

446697

SNRPA
U1 small nuclear ribonucleoprotein A

1

10

High-throughput

0.536

High

539041

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

2

High-throughput

0.536

High

617326

SP100
Nuclear autoantigen Sp-100

1

10

High-throughput

0.536

High

641844

U2AF2
Splicing factor U2AF 65 kDa subunit

1

16

High-throughput

0.536

High

911683

RUXE
Small nuclear ribonucleoprotein E

1

1

High-throughput

0.536

High

911887

RUXF
Small nuclear ribonucleoprotein F

1

3

High-throughput

0.536

High

996752

SSRP1
FACT complex subunit SSRP1

1

11

High-throughput

0.536

High

1034331

SF3B2
Splicing factor 3B subunit 2

1

1

High-throughput

0.536

High

1073047

SF3B3
Splicing factor 3B subunit 3

1

2

High-throughput

0.536

High

1204692

SF3B5
Splicing factor 3B subunit 5

1

1

High-throughput

0.536

High

1204701

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.536

High

1204713

SF3B6
Splicing factor 3B subunit 6

1

11

High-throughput

0.536

High

814643

CDX1
Homeobox protein CDX-1

1

2

High-throughput

0.515

High

739762

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

828828

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

912501

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.513

High

1018827

SF3A3
Splicing factor 3A subunit 3

1

0

High-throughput

0.513

High

1133073

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.513

High

1186239

PHF5A
PHD finger-like domain-containing protein 5A

1

0

High-throughput

0.513

High

165518

SR140
U2 snRNP-associated SURP motif-containing protein

1

8

High-throughput

0.508

High

1204709

PRP19
Pre-mRNA-processing factor 19

1

11

High-throughput

0.508

High

395094

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

962850

MDM2
E3 ubiquitin-protein ligase Mdm2

1

2

Small-scale

0.501

High

316672

ACSL3
Fatty acid CoA ligase Acsl3

1

0

High-throughput

0.493

High

1204705

DJB11
DnaJ homolog subfamily B member 11

1

0

High-throughput

0.493

High

1204676

FBX25
F-box only protein 25

1

0

Small-scale

0.480

High

122865

MEN1
Menin

1

3

High-throughput

0.479

High

123277

CBX4
E3 SUMO-protein ligase CBX4

1

3

High-throughput

0.479

High

149013

CTRO
Citron Rho-interacting kinase

1

8

High-throughput

0.479

High

199776

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

1

High-throughput

0.479

High

214309

SPOP
Speckle-type POZ protein

1

2

High-throughput

0.479

High

227955

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

232924

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

7

High-throughput

0.479

High

233531

NUPR1
Nuclear protein 1

1

5

High-throughput

0.479

High

237405

CCNT2
Cyclin-T2

1

3

High-throughput

0.479

High

244628

BRD4
Bromodomain-containing protein 4

1

6

High-throughput

0.479

High

255901

OBSL1
Obscurin-like protein 1

1

4

High-throughput

0.479

High

263712

PR40A
Pre-mRNA-processing factor 40 homolog A

1

13

High-throughput

0.479

High

268159

EED
Polycomb protein EED

1

18

High-throughput

0.479

High

297518

TOX4
TOX high mobility group box family member 4

1

10

High-throughput

0.479

High

302686

ARHGF
Rho guanine nucleotide exchange factor 15

1

1

High-throughput

0.479

High

347225

MYC
Myc proto-oncogene protein

1

8

High-throughput

0.479

High

360112

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

11

High-throughput

0.479

High

385116

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.479

High

398024

ISG15
Ubiquitin-like protein ISG15

1

5

High-throughput

0.479

High

445461

RSSA
Small ribosomal subunit protein uS2

1

2

High-throughput

0.479

High

523861

XRCC6
X-ray repair cross-complementing protein 6

1

5

High-throughput

0.479

High

530694

ITA4
Integrin alpha-4

1

6

High-throughput

0.479

High

553106

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

561615

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

1

High-throughput

0.479

High

569855

CEBPB
CCAAT/enhancer-binding protein beta

1

8

High-throughput

0.479

High

595611

HXA5
Homeobox protein Hox-A5

1

1

High-throughput

0.479

High

613512

SFPQ
Splicing factor, proline- and glutamine-rich

1

11

High-throughput

0.479

High

632799

TYY1
Transcriptional repressor protein YY1

1

6

High-throughput

0.479

High

651609

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

668802

PML
Protein PML

1

11

High-throughput

0.479

High

720848

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

742380

SYUA
Alpha-synuclein

1

3

High-throughput

0.479

High

749648

BRCA1
Breast cancer type 1 susceptibility protein

1

6

High-throughput

0.479

High

759722

RS19
Small ribosomal subunit protein eS19

1

2

High-throughput

0.479

High

779690

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

822310

KC1D
Casein kinase I isoform delta

1

2

High-throughput

0.479

High

830411

KC1E
Casein kinase I isoform epsilon

1

3

High-throughput

0.479

High

833470

RBM25
RNA-binding protein 25

1

3

High-throughput

0.479

High

841802

CDK9
Cyclin-dependent kinase 9

1

7

High-throughput

0.479

High

848074

MECP2
Methyl-CpG-binding protein 2

1

6

High-throughput

0.479

High

875666

MFAP1
Microfibrillar-associated protein 1

1

1

High-throughput

0.479

High

877790

FOXA1
Hepatocyte nuclear factor 3-alpha

1

2

High-throughput

0.479

High

906003

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

5

High-throughput

0.479

High

916257

RL23A
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

934941

H31
Histone H3.1

1

6

High-throughput

0.479

High

941123

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

983174

UBE3A
Ubiquitin-protein ligase E3A

1

6

High-throughput

0.479

High

990530

CKAP4
Cytoskeleton-associated protein 4

1

7

High-throughput

0.479

High

998860

EP300
Histone acetyltransferase p300

1

9

High-throughput

0.479

High

1014162

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

2

High-throughput

0.479

High

1016924

AKP13
A-kinase anchor protein 13

1

1

High-throughput

0.479

High

1019013

TP53B
TP53-binding protein 1

1

3

High-throughput

0.479

High

1022418

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

2

High-throughput

0.479

High

1026464

RFA4
Replication protein A 30 kDa subunit

1

7

High-throughput

0.479

High

1027105

CBX3
Chromobox protein homolog 3

1

3

High-throughput

0.479

High

1035866

BIRC3
Baculoviral IAP repeat-containing protein 3

1

6

High-throughput

0.479

High

1037839

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

12

High-throughput

0.479

High

1039666

SNW1
SNW domain-containing protein 1

1

5

High-throughput

0.479

High

1052246

SRC8
Src substrate cortactin

1

1

High-throughput

0.479

High

1061486

CUL7
Cullin-7

1

7

High-throughput

0.479

High

1069733

NONO
Non-POU domain-containing octamer-binding protein

1

13

High-throughput

0.479

High

1126279

FA76B
Protein FAM76B

1

1

High-throughput

0.479

High

1133681

RHG21
Rho GTPase-activating protein 21

1

4

High-throughput

0.479

High

1146582

A16L1
Autophagy-related protein 16-1

1

9

High-throughput

0.479

High

1158780

TAF2
Transcription initiation factor TFIID subunit 2

1

1

High-throughput

0.479

High

1166691

WDR82
WD repeat-containing protein 82

1

12

High-throughput

0.479

High

1167882

DJC14
DnaJ homolog subfamily C member 14

1

1

High-throughput

0.479

High

1188514

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

1193115

SLN11
Schlafen family member 11

1

1

High-throughput

0.479

High

1200470

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.479

High

1204668

SMC5
Structural maintenance of chromosomes protein 5

1

5

High-throughput

0.479

High

1204670

NGEF
Ephexin-1

1

5

High-throughput

0.479

High

1204671

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

6

High-throughput

0.479

High

1204673

RB15B
Putative RNA-binding protein 15B

1

11

High-throughput

0.479

High

1204675

FA76A
Protein FAM76A

1

1

High-throughput

0.479

High

1204677

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

4

High-throughput

0.479

High

1204679

ATX2L
Ataxin-2-like protein

1

3

High-throughput

0.479

High

1204680

PSPC1
Paraspeckle component 1

1

13

High-throughput

0.479

High

1204681

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

6

High-throughput

0.479

High

1204682

RBP56
TATA-binding protein-associated factor 2N

1

12

High-throughput

0.479

High

1204683

CSN5
COP9 signalosome complex subunit 5

1

10

High-throughput

0.479

High

1204686

CDC5L
Cell division cycle 5-like protein

1

4

High-throughput

0.479

High

1204688

ANM1
Protein arginine N-methyltransferase 1

1

5

High-throughput

0.479

High

1204696

NSRP1
Nuclear speckle splicing regulatory protein 1

1

1

High-throughput

0.479

High

1204698

PKHA4
Pleckstrin homology domain-containing family A member 4

1

15

High-throughput

0.479

High

1204700

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

2

High-throughput

0.479

High

1204702

DCA13
DDB1- and CUL4-associated factor 13

1

10

High-throughput

0.479

High

1204706

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

1204707

VAV3
Guanine nucleotide exchange factor VAV3

1

5

High-throughput

0.479

High

1204697

TMX1
Thioredoxin-related transmembrane protein 1

1

1

High-throughput

0.470

High

204696

E41L2
Band 4.1-like protein 2

1

0

High-throughput

0.458

High

214981

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.458

High

335137

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.458

High

817698

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

0

High-throughput

0.458

High

893572

SEM1
26S proteasome complex subunit SEM1

1

0

Small-scale

0.458

High

918492

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

929320

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.458

High

1067755

PDIA6
Protein disulfide-isomerase A6

1

0

High-throughput

0.458

High

1164840

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

0

High-throughput

0.458

High

1189851

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.458

High

1204672

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.458

High

1204674

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

1204678

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

0

High-throughput

0.458

High

1204685

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

0

High-throughput

0.458

High

1204687

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.458

High

1204689

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

1204690

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.458

High

1204693

NUSAP
Nucleolar and spindle-associated protein 1

1

0

High-throughput

0.458

High

1204699

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1204704

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1204708

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.458

High

1204712

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

0

High-throughput

0.458

High

1204714

SPIN1
Spindlin-1

1

0

High-throughput

0.458

High

497260

TAU
Microtubule-associated protein tau

1

8

High-throughput

0.445

High

853939

NCBP2
Nuclear cap-binding protein subunit 2

1

14

High-throughput

0.445

High

1075690

SF01
Splicing factor 1

1

8

High-throughput

0.445

High

1130281

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

6

High-throughput

0.445

High

1153276

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.445

High

1204694

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.445

High

1173978

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

8

Small-scale

0.437

High

581784

VCAM1
Vascular cell adhesion protein 1

1

3

High-throughput

0.407

High

674689

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024