Protein: Q961D1
Cyclin-K

Gene: Q961D1, CycK
Organism: Drosophila melanogaster
Interactions: 174
UniProt ID: Q961D1

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0008024 - cyclin/CDK positive transcription elongation factor complex
GO:0032786 - positive regulation of DNA-templated transcription, elongation
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0061575 - cyclin-dependent protein serine/threonine kinase activator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1379260

CDK12
Cyclin-dependent kinase 12

4

20

Small-scale

0.870

High

660459

CDK2
Cyclin-dependent kinase 2

3

20

High-throughput

0.839

High

660401

CDK1
Cyclin-dependent kinase 1

2

20

High-throughput

0.785

High

356666

PLK4
Serine/threonine-protein kinase PLK4

1

3

High-throughput

0.656

High

1265592

Q7K306
cyclin-dependent kinase

1

20

High-throughput

0.656

High

1303700

AKT1
RAC serine/threonine-protein kinase

1

8

High-throughput

0.656

High

1378153

CYCG
Cyclin G

1

8

High-throughput

0.656

High

1379237

Q9VEH1
LD04521p

1

20

High-throughput

0.656

High

1379283

Q9VZP3
Cyclin J, isoform A

1

8

High-throughput

0.656

High

478824

BCD
Homeotic protein bicoid

3

4

High-throughput

0.653

High

117888

M9MRD8
Cyclin-dependent kinase-like 2

1

20

High-throughput

0.621

High

235161

O46308
non-specific serine/threonine protein kinase

1

16

High-throughput

0.621

High

197593

PAX6
Paired box protein Pax-6

2

2

High-throughput

0.594

High

594760

7UP1
Steroid receptor seven-up, isoforms B/C

2

16

High-throughput

0.594

High

627223

DLL
Homeotic protein distal-less

2

2

High-throughput

0.594

High

638324

SINA
E3 ubiquitin-protein ligase sina

2

2

High-throughput

0.594

High

814611

OPA
Pair-rule protein odd-paired

2

2

High-throughput

0.594

High

928380

CAUP
Homeobox protein caupolican

2

4

High-throughput

0.594

High

942053

OTP
Homeobox protein orthopedia

2

3

High-throughput

0.594

High

1174477

DICH
SOX domain-containing protein dichaete

2

7

High-throughput

0.594

High

1379218

FUSIL
RNA-binding protein fusilli

2

4

High-throughput

0.594

High

1379230

Q9V472
DLim1

2

1

High-throughput

0.594

High

885651

MNB
Serine/threonine-protein kinase minibrain

1

20

High-throughput

0.590

High

1344776

Q8SZA4
non-specific serine/threonine protein kinase

1

7

High-throughput

0.590

High

1379257

Q9VMN3
Cyclin-dependent kinase-like 2

1

20

High-throughput

0.590

High

1377856

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

3

4

High-throughput

0.589

High

1014350

UBX
Homeotic protein ultrabithorax

1

4

Small-scale

0.573

High

1379228

Q9U8L5
Dorsocross1, isoform A

2

0

High-throughput

0.569

High

1379251

Q9VJL7
IP01243p

2

0

High-throughput

0.569

High

1379261

INT15
Integrator complex subunit 15

2

0

High-throughput

0.569

High

1379263

ELBA2
Early boundary activity protein 2

2

0

High-throughput

0.569

High

1379270

Q9VRY7
GH13213p

2

0

High-throughput

0.569

High

1267525

NITO
RNA-binding protein spenito

2

7

Small-scale

0.552

High

1261699

Q7JR80
SD23764p

2

6

High-throughput

0.542

High

1344742

Q8SZ28
RE21371p

2

2

High-throughput

0.542

High

1379229

Q9V3I9
FI22161p1

2

2

High-throughput

0.542

High

1379233

Q9VAX3
RE10833p

2

4

High-throughput

0.542

High

1379258

POLZ2
DNA polymerase zeta subunit 2

2

1

High-throughput

0.542

High

304868

E2F2
Transcription factor E2F2

1

10

High-throughput

0.508

High

756477

ECR
Ecdysone receptor

1

17

High-throughput

0.508

High

1010896

L2EFL
Protein lethal(2)essential for life

1

6

High-throughput

0.508

High

1273651

Q7PLI0
Adherens junction protein p120

1

6

High-throughput

0.508

High

1321216

Q8MSD1
LD05256p

1

1

High-throughput

0.508

High

1379225

Q9N6D8
GH11591p

1

9

High-throughput

0.508

High

1379242

Q9VHN1
Cyclin-dependent kinases regulatory subunit

1

20

High-throughput

0.508

High

1379253

Q9VL21
LD11652p

1

6

High-throughput

0.508

High

1379269

Q9VRX0
IP01005p

1

1

High-throughput

0.508

High

1379271

ORB2
Translational regulator orb2

1

4

High-throughput

0.508

High

1379273

Q9VT94
RBR-type E3 ubiquitin transferase

1

8

High-throughput

0.508

High

1379281

Q9VXL5
LD19131p

1

4

High-throughput

0.508

High

1379286

Q9W102
Origin recognition complex subunit 4

1

8

High-throughput

0.508

High

2322

A0A0B4KEQ7
Regulatory protein zeste

1

1

High-throughput

0.494

High

114701

H1UUK0
FI17807p1

1

3

High-throughput

0.494

High

1052709

Q058W3
IP14616p

1

2

High-throughput

0.494

High

1285944

Q86LC7
Deformed epidermal autoregulatory factor-1, isoform B

1

1

High-throughput

0.494

High

1069955

Q0E9A0
FI21293p1

1

0

High-throughput

0.486

High

1379235

NPL4
Nuclear protein localization protein 4 homolog

1

0

High-throughput

0.486

High

118497

M9NEG1
Maternal gene required for meiosis, isoform F

1

2

High-throughput

0.481

High

120032

M9PC68
Dpt-YFP repressor by overexpression, isoform D

1

1

High-throughput

0.481

High

121995

M9PH39
histone acetyltransferase

1

9

High-throughput

0.481

High

1172838

DEAF1
Deformed epidermal autoregulatory factor 1

1

1

High-throughput

0.481

High

1173029

ARA
Homeobox protein araucan

1

4

High-throughput

0.481

High

1216713

Q5U0V6
Cell division cycle 14, isoform B

1

4

High-throughput

0.481

High

1266061

Q7K3Q3
Regulatory protein zeste

1

1

High-throughput

0.481

High

1268782

Q7KRS7
Hephaestus, isoform G

1

5

High-throughput

0.481

High

1379219

SIRT2
NAD-dependent protein deacetylase Sirt2

1

5

High-throughput

0.481

High

1379226

Q9NF31
EG:BACN25G24.3 protein

1

1

High-throughput

0.481

High

1379285

SF3B3
Splicing factor 3B subunit 3

1

4

High-throughput

0.481

High

1379232

CLAMP
Transcription factor Clamp

1

0

High-throughput

0.473

High

55452

A1Z9E3
Elongation factor Tu

1

2

High-throughput

0.464

High

234938

PGAM5
Serine/threonine-protein phosphatase Pgam5, mitochondrial

1

1

High-throughput

0.464

High

584289

CYPR
Peptidyl-prolyl cis-trans isomerase, rhodopsin-specific isozyme

1

5

High-throughput

0.464

High

669573

GNAL
Guanine nucleotide-binding protein subunit alpha homolog

1

3

High-throughput

0.464

High

828130

PNUT
Protein peanut

1

1

High-throughput

0.464

High

1343705

Q8SXF0
Small ribosomal subunit protein uS9m

1

1

High-throughput

0.464

High

1343800

Q8SXL5
RE09177p

1

1

High-throughput

0.464

High

1344005

GMPPA
Mannose-1-phosphate guanylyltransferase regulatory subunit alpha

1

2

High-throughput

0.464

High

1379220

Q9I7L0
LP01847p

1

4

High-throughput

0.464

High

1379227

CEG1A
Centaurin-gamma-1A

1

1

High-throughput

0.464

High

1379247

Q9VIH1
CG9273 protein

1

8

High-throughput

0.464

High

1379250

Q9VJ98
GH05617p

1

1

High-throughput

0.464

High

1379254

Q9VL27
Alpha-galactosidase

1

1

High-throughput

0.464

High

1379259

Q9VNI9
IP18173p

1

1

High-throughput

0.464

High

1379268

Q9VRQ4
LD47944p

1

1

High-throughput

0.464

High

1379272

FRY
Protein furry

1

1

High-throughput

0.464

High

1379277

MSIR6
RNA-binding protein Musashi homolog Rbp6

1

4

High-throughput

0.464

High

1379280

Q9VX05
Uncharacterized protein

1

1

High-throughput

0.464

High

1286013

Q86NL5
RE66853p

1

4

High-throughput

0.457

High

1345178

Q8T0H5
LD03185p

1

5

High-throughput

0.457

High

1378299

Q95TP4
LD33277p

1

1

High-throughput

0.457

High

1379256

Q9VLW7
Cell division cycle 14, isoform A

1

4

High-throughput

0.457

High

1379292

Q9W523
Polyhomeotic distal, isoform A

1

3

High-throughput

0.457

High

47040

A0A4P7V9T9
polynucleotide adenylyltransferase

1

1

High-throughput

0.451

High

53891

A1Z866
CAP, isoform I

1

3

High-throughput

0.451

High

91317

C6SV36
IP19903p

1

2

High-throughput

0.451

High

99400

F3YDN7
IP15980p

1

1

High-throughput

0.451

High

1304328

Q8INY6
RH05790p

1

1

High-throughput

0.451

High

1378088

Q95T44
GH23604p

1

1

High-throughput

0.451

High

1379248

Q9VIX7
Fondue, isoform B

1

1

High-throughput

0.451

High

1379284

Q9VZV3
PAN2-PAN3 deadenylation complex subunit PAN3

1

4

High-throughput

0.451

High

1269663

Q7KU01
Phosphatase 1 nuclear targeting subunit, isoform D

1

5

High-throughput

0.445

High

1275248

Q7YZ99
Serine-arginine repetitive matrix 2/3/4, isoform A

1

5

High-throughput

0.445

High

1345118

Q8T0D1
LD10183p

1

1

High-throughput

0.445

High

1346117

PUF68
Poly(U)-binding-splicing factor hfp

1

5

High-throughput

0.445

High

1377214

Q95RB1
Pre-mRNA-splicing factor RBM22

1

2

High-throughput

0.445

High

1379275

Q9VU43
Serine/arginine repetitive matrix protein 1

1

1

High-throughput

0.445

High

1379293

Q9XZ21
Something that sticks like glue, isoform A

1

5

High-throughput

0.445

High

95435

E1JJN5
Uncharacterized protein, isoform D

1

3

High-throughput

0.439

High

95627

E3CTS2
MIP27658p

1

3

High-throughput

0.439

High

117981

M9MRQ3
Uncharacterized protein

1

1

High-throughput

0.439

High

120600

M9PDP3
Fondue, isoform D

1

1

High-throughput

0.439

High

122371

M9PJA1
Uncharacterized protein, isoform F

1

1

High-throughput

0.439

High

615087

PTC
Protein patched

1

1

High-throughput

0.439

High

839945

PLU
DNA replication inhibitor plutonium

1

6

High-throughput

0.439

High

1069957

Q0E9A2
No extended memory, isoform C

1

1

High-throughput

0.439

High

1275188

Q7YU88
SD08871p

1

1

High-throughput

0.439

High

1275299

Q7Z2C5
Uncharacterized protein

1

4

High-throughput

0.439

High

1286068

Q86P80
CAP, isoform K

1

5

High-throughput

0.439

High

1303677

Q8IN96
pyrroline-5-carboxylate reductase

1

1

High-throughput

0.439

High

1343851

Q8SXN9
polynucleotide adenylyltransferase

1

1

High-throughput

0.439

High

1379224

HECA
Headcase protein [Cleaved into: Headcase short protein]

1

1

High-throughput

0.439

High

1379243

Q9VI00
FI24305p1

1

4

High-throughput

0.439

High

1379276

Q9VUX7
GH16214p

1

1

High-throughput

0.439

High

1379294

X2JEH3
Uncharacterized protein, isoform E

1

1

High-throughput

0.439

High

1379278

Q9VVU4
CBF1-interacting co-repressor CIR N-terminal domain-containing protein

1

0

High-throughput

0.426

High

1261674

Q7JR72
No extended memory, isoform A

1

1

High-throughput

0.417

High

1285306

Q868J0
PLU

1

6

High-throughput

0.417

High

1303295

Q8IMI6
Headcase, isoform B

1

1

High-throughput

0.417

High

1305583

Q8IQN4
Protein phosphatase 1 regulatory subunit 12B

1

4

High-throughput

0.417

High

1344644

Q8SYU4
RE33778p

1

3

High-throughput

0.417

High

1344714

Q8SYZ4
NAD-dependent protein deacetylase

1

5

High-throughput

0.417

High

1345387

Q8T0P7
GH15037p

1

4

High-throughput

0.417

High

1346537

Q8T9L6
GM01240p

1

4

High-throughput

0.417

High

1379223

Q9I7T8
PAN2-PAN3 deadenylation complex subunit PAN3

1

2

High-throughput

0.417

High

1379238

Q9VEJ3
Pyrroline-5-carboxylate reductase

1

1

High-throughput

0.417

High

1379274

Q9VTH5
Dpt-YFP repressor by overexpression, isoform B

1

1

High-throughput

0.417

High

1379282

Q9VYF9
RE28286p

1

5

High-throughput

0.417

High

1379289

Q9W3X2
Uncharacterized protein, isoform A

1

3

High-throughput

0.417

High

1171611

SNAP
Alpha-soluble NSF attachment protein

1

3

High-throughput

0.407

High

1263555

GMPPB
Mannose-1-phosphate guanylyltransferase catalytic subunit beta

1

2

High-throughput

0.407

High

1304232

Q8INW7
FI11475p

1

2

High-throughput

0.407

High

1378350

Q95TU2
LD23187p

1

2

High-throughput

0.407

High

1379222

LAR4
La-related protein Larp4B

1

7

High-throughput

0.407

High

1379249

Q9VIZ3
RNA helicase

1

2

High-throughput

0.407

High

1379262

Q9VQ94
LP05220p

1

3

High-throughput

0.407

High

1379264

Q9VQF5
Cwc25

1

1

High-throughput

0.407

High

1379266

Q9VQK5
LD24714p

1

7

High-throughput

0.407

High

1379221

Q9I7P3
BBSome complex member BBS5

3

0

High-throughput

0.340

High

1285405

UNK
RING finger protein unkempt

2

0

High-throughput

0.310

High

1345700

Q8T3W6
AT27166p

2

0

High-throughput

0.310

High

1379231

PSMF1
Proteasome inhibitor PI31 subunit

2

0

High-throughput

0.310

High

1379265

Q9VQI4
GH27752p

2

0

High-throughput

0.310

High

1379279

Q9VWU8
GH12946p

2

0

High-throughput

0.310

High

1379288

Q9W3R3
FI06480p

2

0

High-throughput

0.310

High

1379290

Q9W483
GH18971p

2

0

High-throughput

0.310

High

234862

O46070
EG:25E8.4 protein

1

0

High-throughput

0.265

Low

839696

STAR
Protein Star

1

0

High-throughput

0.265

Low

1173747

SEM2A
Semaphorin-2A

1

0

High-throughput

0.265

Low

1379234

Q9VBC6
LD14717p

1

0

High-throughput

0.265

Low

1379236

Q9VCX6
AT09144p

1

0

High-throughput

0.265

Low

1379240

Q9VF43
GEO12016p1

1

0

High-throughput

0.265

Low

1379244

Q9VI02
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

1379245

Q9VI04
Beta-ureidopropionase

1

0

High-throughput

0.265

Low

1379246

Q9VIF2
GM01519p

1

0

High-throughput

0.265

Low

1379252

Q9VL03
Uncharacterized protein, isoform B

1

0

High-throughput

0.265

Low

1379255

MPPE1
Metallophosphoesterase 1 homolog

1

0

High-throughput

0.265

Low

1379267

Q9VQW4
IP21067p

1

0

High-throughput

0.265

Low

1379287

Q9W3K6
LD35927p

1

0

High-throughput

0.265

Low

1379291

Q9W512
Uncharacterized protein, isoform B

1

0

High-throughput

0.265

Low

1302713

Q8IGE8
RH36596p

1

0

High-throughput

0.238

Low

1262230

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

0

High-throughput

0.232

Low

1266882

Q7K581
SD01637p

1

0

High-throughput

0.232

Low

1379239

Q9VES0
FI23980p1

1

0

High-throughput

0.232

Low

1379241

Q9VFF2
FI01402p

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025