Protein: MPH6
M-phase phosphoprotein 6

Gene: MPH6, MPHOSPH6
Organism: Homo sapiens
Interactions: 78
UniProt ID: Q99547

Gene Ontology (top 5):
GO:0000178 - exosome (RNase complex)
GO:0000460 - maturation of 5.8S rRNA
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1046325

EXOS2
Exosome complex component RRP4

6

1

Small-scale

0.937

High

1304450

EXOS3
Exosome complex component RRP40

7

0

Small-scale

0.917

High

1063758

EXOS7
Exosome complex component RRP42

5

5

Small-scale

0.716

High

1284955

EXOS8
Exosome complex component RRP43

5

5

Small-scale

0.716

High

1304457

EXOS1
Exosome complex component CSL4

5

3

Small-scale

0.716

High

1304448

EXOS4
Exosome complex component RRP41

5

6

Small-scale

0.714

High

966462

EXOSX
Exosome complex component 10

6

0

Small-scale

0.698

High

1304449

EXOS5
Exosome complex component RRP46

4

6

Small-scale

0.696

High

986713

EXOS9
Exosome complex component RRP45

4

5

Small-scale

0.689

High

1130047

EXOS6
Exosome complex component MTR3

3

8

Small-scale

0.660

High

787002

MTREX
Exosome RNA helicase MTR4

4

0

Small-scale

0.658

High

1047035

C1D
Nuclear nucleic acid-binding protein C1D

3

0

Small-scale

0.638

High

230420

ZC3H1
Zinc finger C3H1 domain-containing protein

2

1

High-throughput

0.611

High

1257151

DI3L1
DIS3-like exonuclease 1

2

1

High-throughput

0.611

High

1157895

ZCHC8
Zinc finger CCHC domain-containing protein 8

2

0

High-throughput

0.585

High

1304460

RBM7
RNA-binding protein 7

2

0

High-throughput

0.585

High

857012

THOP1
Thimet oligopeptidase

2

0

High-throughput

0.551

High

233603

NUPR1
Nuclear protein 1

2

0

Small-scale

0.551

High

370274

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

388678

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.541

High

849947

APLP1
Amyloid beta precursor like protein 1

1

2

High-throughput

0.541

High

1016316

TBL3
Transducin beta-like protein 3

1

2

High-throughput

0.536

High

1067236

WDR43
WD repeat-containing protein 43

1

2

High-throughput

0.536

High

1070030

PWP2
Periodic tryptophan protein 2 homolog

1

2

High-throughput

0.536

High

1218371

WDR75
WD repeat-containing protein 75

1

2

High-throughput

0.536

High

1246467

WDR36
WD repeat-containing protein 36

1

2

High-throughput

0.536

High

1256118

UTP15
U3 small nucleolar RNA-associated protein 15 homolog

1

2

High-throughput

0.536

High

1282700

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

2

High-throughput

0.536

High

1304455

WDR3
WD repeat-containing protein 3

1

3

High-throughput

0.536

High

1304456

RRP44
Exosome complex exonuclease RRP44

1

1

High-throughput

0.536

High

387366

P53
Cellular tumor antigen p53

1

0

High-throughput

0.518

High

980639

TLE1
Transducin-like enhancer protein 1

1

0

High-throughput

0.518

High

1034191

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.518

High

1130089

RBM48
RNA-binding protein 48

1

0

High-throughput

0.518

High

1304453

ZHX1
Zinc fingers and homeoboxes protein 1

1

0

High-throughput

0.518

High

395560

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.515

High

177534

NVL
Nuclear valosin-containing protein-like

1

0

High-throughput

0.513

High

1232767

ZCHC7
Zinc finger CCHC domain-containing protein 7

1

0

High-throughput

0.513

High

1242448

PAPD5
Terminal nucleotidyltransferase 4B

1

0

High-throughput

0.513

High

1299847

LENG8
Leukocyte receptor cluster member 8

1

0

High-throughput

0.513

High

1304445

ZN106
Zinc finger protein 106

1

0

High-throughput

0.513

High

1304446

NOL11
Nucleolar protein 11

1

0

High-throughput

0.513

High

1304461

UTP18
U3 small nucleolar RNA-associated protein 18 homolog

1

0

High-throughput

0.513

High

358872

CRYAA
Alpha-crystallin A chain

1

1

High-throughput

0.501

High

442420

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.479

High

1304331

SORT
Sortilin

1

1

High-throughput

0.479

High

1133102

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.460

High

122956

MEN1
Menin

1

0

High-throughput

0.458

High

149204

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

237297

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.458

High

267057

SRS10
Serine/arginine-rich splicing factor 10

1

0

Small-scale

0.458

High

295166

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

298741

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

379769

MYCN
N-myc proto-oncogene protein

1

0

High-throughput

0.458

High

877847

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

918633

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

925552

RAC1
Ras-related C3 botulinum toxin substrate 1

1

0

High-throughput

0.458

High

952578

H33
Histone H3.3

1

0

High-throughput

0.458

High

1167960

GGYF2
GRB10-interacting GYF protein 2

1

0

High-throughput

0.458

High

1201618

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1256351

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1293933

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1304454

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

1304459

HBS1L
HBS1-like protein

1

0

High-throughput

0.458

High

275928

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

0

High-throughput

0.438

High

314675

PARN
Poly(A)-specific ribonuclease PARN

1

0

High-throughput

0.438

High

365031

FRIL
Ferritin light chain

1

0

High-throughput

0.438

High

840803

DYN2
Dynamin-2

1

0

High-throughput

0.438

High

847063

SMCA4
Transcription activator BRG1

1

0

High-throughput

0.438

High

893130

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.438

High

1137554

RIF1
Telomere-associated protein RIF1

1

0

High-throughput

0.438

High

1232128

RHG18
Rho GTPase-activating protein 18

1

0

High-throughput

0.438

High

1304451

AATF
Protein AATF

1

0

High-throughput

0.438

High

1304458

SKAP
Small kinetochore-associated protein

1

0

High-throughput

0.438

High

1304462

SNX9
Sorting nexin-9

1

0

High-throughput

0.438

High

233957

GDF9
Growth/differentiation factor 9

1

0

High-throughput

0.282

High

1304452

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.282

High

1304447

DLRB1
Dynein light chain roadblock-type 1

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024