Protein: GBG12
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12

Gene: GBG12, GNG12
Organism: Homo sapiens
Interactions: 93
UniProt ID: Q9UBI6

Gene Ontology (top 5):
GO:0005834 - heterotrimeric G-protein complex
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0030165 - PDZ domain binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

921073

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

5

20

Small-scale

0.920

High

921761

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

4

20

Small-scale

0.873

High

560893

GBB3
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3

2

20

Small-scale

0.806

High

1050829

FHL2
Four and a half LIM domains protein 2

5

1

High-throughput

0.655

High

1334920

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

20

Small-scale

0.647

High

1349375

PD1L1
Programmed cell death 1 ligand 1

1

1

High-throughput

0.618

High

793507

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.586

High

1260197

HDAC7
Histone deacetylase 7

2

1

High-throughput

0.553

High

373439

CATA
Catalase

2

0

High-throughput

0.547

High

598359

FLNA
Filamin-A

1

2

High-throughput

0.536

High

837659

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

20

High-throughput

0.536

High

1032887

PHLP
Phosducin-like protein

1

9

High-throughput

0.536

High

1053448

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

20

High-throughput

0.536

High

1245683

MSPD2
Motile sperm domain-containing protein 2

1

3

High-throughput

0.536

High

1024843

DUS4
Dual specificity protein phosphatase 4

2

1

High-throughput

0.521

High

725052

MYH9
Myosin-9

1

0

High-throughput

0.513

High

836053

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.513

High

1270564

CDKL2
Cyclin-dependent kinase-like 2

1

0

High-throughput

0.513

High

1336452

KC1G1
Casein kinase I isoform gamma-1

1

0

High-throughput

0.513

High

537777

INSRR
Insulin receptor-related protein

1

3

High-throughput

0.500

High

600694

EPHA1
Ephrin type-A receptor 1

1

3

High-throughput

0.500

High

665350

EPHA2
Ephrin type-A receptor 2

1

3

High-throughput

0.500

High

846536

BLK
Tyrosine-protein kinase Blk

1

3

High-throughput

0.489

High

178026

TMPS2
Transmembrane protease serine 2

1

1

High-throughput

0.479

High

429145

ADRB2
Beta-2 adrenergic receptor

1

2

High-throughput

0.479

High

526084

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

965876

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

1263924

CLC4D
C-type lectin domain family 4 member D

1

2

High-throughput

0.479

High

1269827

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1354049

CLC4E
C-type lectin domain family 4 member E

1

2

High-throughput

0.479

High

210343

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

504892

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

610521

CBL
E3 ubiquitin-protein ligase CBL

1

0

High-throughput

0.458

High

726454

BASI
Basigin

1

0

High-throughput

0.458

High

870919

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

High-throughput

0.458

High

916044

RHOB
Rho-related GTP-binding protein RhoB

1

0

High-throughput

0.458

High

932424

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

1066818

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1330533

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

1354050

RIPK3
Receptor-interacting serine/threonine-protein kinase 3

1

0

High-throughput

0.458

High

887975

CD81
CD81 antigen

1

4

High-throughput

0.445

High

233669

NUPR1
Nuclear protein 1

1

1

High-throughput

0.437

High

309128

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.437

High

348133

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.437

High

379977

MYCN
N-myc proto-oncogene protein

1

2

High-throughput

0.437

High

591131

BTF3
Transcription factor BTF3

1

1

High-throughput

0.437

High

970041

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.437

High

1051927

IF4A2
Eukaryotic initiation factor 4A-II

1

1

High-throughput

0.437

High

1057247

KCTD2
BTB/POZ domain-containing protein KCTD2

1

11

Small-scale

0.437

High

1064224

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.437

High

1163891

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.437

High

1327685

RNF38
E3 ubiquitin-protein ligase RNF38

1

1

Small-scale

0.437

High

1343738

ANLN
Anillin

1

1

High-throughput

0.437

High

1348074

KCTD5
BTB/POZ domain-containing protein KCTD5

1

11

Small-scale

0.437

High

1354046

HDAC6
Histone deacetylase 6

1

1

High-throughput

0.437

High

529844

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

1318880

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

718271

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.407

High

157376

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

0

High-throughput

0.279

Low

758353

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.279

Low

1016526

TWF1
Twinfilin-1

1

0

High-throughput

0.279

Low

1088446

F264
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4

1

0

High-throughput

0.279

Low

1149508

Z518A
Zinc finger protein 518A

1

0

High-throughput

0.279

Low

1201237

PIM3
Serine/threonine-protein kinase pim-3

1

0

High-throughput

0.279

Low

1217202

LACC1
Purine nucleoside phosphorylase LACC1

1

0

High-throughput

0.279

Low

1219081

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

1238540

BANP
Protein BANP

1

0

High-throughput

0.279

Low

1257342

HASP
Serine/threonine-protein kinase haspin

1

0

High-throughput

0.279

Low

1334008

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.279

Low

1354048

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.279

Low

780253

CCNF
Cyclin-F

1

0

High-throughput

0.269

Low

1315381

KLF16
Krueppel-like factor 16

1

0

High-throughput

0.261

Low

123060

MEN1
Menin

1

0

High-throughput

0.249

Low

129062

PLK4
Serine/threonine-protein kinase PLK4

1

0

Small-scale

0.249

Low

149765

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.249

Low

328985

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.249

Low

589933

TBP
TATA-box-binding protein

1

0

Small-scale

0.249

Low

808984

YAP1
Transcriptional coactivator YAP1

1

0

High-throughput

0.249

Low

968801

MEF2A
Myocyte-specific enhancer factor 2A

1

0

Small-scale

0.249

Low

1016891

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.249

Low

1045372

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.249

Low

1046189

DX39B
Spliceosome RNA helicase DDX39B

1

0

High-throughput

0.249

Low

1119503

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.249

Low

1119654

MIDN
Midnolin

1

0

High-throughput

0.249

Low

1148839

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1256452

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.249

Low

1284263

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.249

Low

1318518

TRI31
E3 ubiquitin-protein ligase TRIM31

1

0

High-throughput

0.249

Low

1319100

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.249

Low

1333780

ECT2
Protein ECT2

1

0

High-throughput

0.249

Low

1345446

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.249

Low

1354047

SEPT9
Septin-9

1

0

Small-scale

0.249

Low

1304792

ZBT18
Zinc finger and BTB domain-containing protein 18

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024