Protein: HIP1
Huntingtin-interacting protein 1 (HIP-1) (Huntingtin-interacting protein I) (HIP-I)

Gene: HIP1
Organism: Homo sapiens
Interactions: 152
UniProt ID: O00291

Gene Ontology (top 5):
GO:0005154 - epidermal growth factor receptor binding
GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

124337

HIP1
Huntingtin-interacting protein 1

6

15

Small-scale

0.943

High

124353

HIP1R
Huntingtin-interacting protein 1-related protein

5

15

Small-scale

0.935

High

124364

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

11

Small-scale

0.793

High

124384

RD23B
UV excision repair protein RAD23 homolog B

2

5

High-throughput

0.783

High

124378

HD
Huntingtin

7

3

Small-scale

0.749

High

124394

CLH1
Clathrin heavy chain 1

7

4

Small-scale

0.744

High

124396

DEUP1
Deuterosome assembly protein 1

3

18

High-throughput

0.667

High

124481

GLSL
Glutaminase liver isoform, mitochondrial

3

4

High-throughput

0.665

High

124361

CLCB
Clathrin light chain B

3

6

Small-scale

0.664

High

124360

CLCA
Clathrin light chain A

3

6

High-throughput

0.662

High

124458

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

3

0

High-throughput

0.632

High

124454

CPNE2
Copine-2

2

2

High-throughput

0.628

High

124347

PRKN
E3 ubiquitin-protein ligase parkin

1

11

High-throughput

0.618

High

124411

TCEA2
Transcription elongation factor A protein 2

2

3

High-throughput

0.606

High

124440

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

3

High-throughput

0.606

High

124444

LNX1
E3 ubiquitin-protein ligase LNX

2

3

High-throughput

0.606

High

124461

SYT17
Synaptotagmin-17

2

2

High-throughput

0.606

High

124407

DAZP2
DAZ-associated protein 2

2

0

High-throughput

0.601

High

124474

IFT57
Intraflagellar transport protein 57 homolog

2

0

Small-scale

0.593

High

124356

EGFR
Epidermal growth factor receptor

2

10

Small-scale

0.584

High

124390

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

124406

CASP8
Caspase-8

2

3

Small-scale

0.584

High

124471

RPRM
Protein reprimo

2

0

High-throughput

0.580

High

124473

CYRIB
CYFIP-related Rac1 interactor B

2

0

High-throughput

0.580

High

124395

REL
Proto-oncogene c-Rel

1

2

High-throughput

0.573

High

124358

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

124382

CLH2
Clathrin heavy chain 2

1

4

Small-scale

0.568

High

124339

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

6

High-throughput

0.560

High

124456

CFA53
Cilia- and flagella-associated protein 53

2

13

High-throughput

0.553

High

124366

TAU
Microtubule-associated protein tau

2

9

High-throughput

0.552

High

124355

AP2A1
AP-2 complex subunit alpha-1

1

5

Small-scale

0.541

High

124379

RS10
Small ribosomal subunit protein eS10

1

2

High-throughput

0.541

High

124341

GAK
Cyclin-G-associated kinase

1

16

High-throughput

0.536

High

124352

AUXI
Auxilin

1

8

High-throughput

0.536

High

124363

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.536

High

124370

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

5

High-throughput

0.536

High

124374

MYH9
Myosin-9

1

14

High-throughput

0.536

High

124380

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.536

High

124467

PAAT
ATPase PAAT

1

1

High-throughput

0.536

High

124476

GTSE1
G2 and S phase-expressed protein 1

1

3

High-throughput

0.536

High

124485

MB212
Protein mab-21-like 2

1

1

High-throughput

0.536

High

124351

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.518

High

124408

PLEC
Plectin

1

11

High-throughput

0.515

High

124344

TGM5
Protein-glutamine gamma-glutamyltransferase 5

1

2

High-throughput

0.515

High

124346

ZBT14
Zinc finger and BTB domain-containing protein 14

1

1

High-throughput

0.515

High

124349

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

4

High-throughput

0.515

High

124369

SCP2
Sterol carrier protein 2

1

1

High-throughput

0.515

High

124372

CTNB1
Catenin beta-1

1

5

High-throughput

0.515

High

124375

TRI23
E3 ubiquitin-protein ligase TRIM23

1

2

High-throughput

0.515

High

124377

CDN2C
Cyclin-dependent kinase 4 inhibitor C

1

6

High-throughput

0.515

High

124383

TERF1
Telomeric repeat-binding factor 1

1

4

High-throughput

0.515

High

124397

GABP1
GA-binding protein subunit beta-1

1

4

High-throughput

0.515

High

124399

RBBP4
Histone-binding protein RBBP4

1

3

High-throughput

0.515

High

124402

SNW1
SNW domain-containing protein 1

1

4

High-throughput

0.515

High

124409

RHEB
GTP-binding protein Rheb

1

5

High-throughput

0.515

High

124433

SPART
Spartin

1

3

High-throughput

0.515

High

124438

RNF10
E3 ubiquitin-protein ligase RNF10

1

3

High-throughput

0.515

High

124439

KCD17
BTB/POZ domain-containing protein KCTD17

1

6

High-throughput

0.515

High

124447

RAB2B
Ras-related protein Rab-2B

1

2

High-throughput

0.515

High

124448

BSND
Barttin

1

1

High-throughput

0.515

High

124452

SPSB1
SPRY domain-containing SOCS box protein 1

1

15

High-throughput

0.515

High

124453

HBAP1
HSPB1-associated protein 1

1

1

High-throughput

0.515

High

124465

LHX5
LIM/homeobox protein Lhx5

1

1

High-throughput

0.515

High

124470

TIGAR
Fructose-2,6-bisphosphatase TIGAR

1

2

High-throughput

0.515

High

124472

BRWD1
Bromodomain and WD repeat-containing protein 1

1

8

High-throughput

0.515

High

124486

ACL7B
Actin-like protein 7B

1

14

High-throughput

0.515

High

124424

ZFP1
Zinc finger protein 1 homolog

1

0

High-throughput

0.513

High

124436

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.513

High

124415

MK06
Mitogen-activated protein kinase 6

1

11

High-throughput

0.508

High

124400

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

16

Small-scale

0.501

High

124445

FBX25
F-box only protein 25

1

8

Small-scale

0.501

High

124469

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

3

Small-scale

0.501

High

123137

CBX4
E3 SUMO-protein ligase CBX4

1

0

High-throughput

0.493

High

124342

TELT
Telethonin

1

0

High-throughput

0.493

High

124357

CO2A1
Collagen alpha-1(II) chain

1

0

High-throughput

0.493

High

124371

MPI
Mannose-6-phosphate isomerase

1

0

High-throughput

0.493

High

124376

8ODP
Oxidized purine nucleoside triphosphate hydrolase

1

0

High-throughput

0.493

High

124398

ECHP
Peroxisomal bifunctional enzyme

1

0

High-throughput

0.493

High

124404

C1D
Nuclear nucleic acid-binding protein C1D

1

0

High-throughput

0.493

High

124405

BAAT
Bile acid-CoA:amino acid N-acyltransferase

1

0

High-throughput

0.493

High

124410

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.493

High

124412

NAB2
NGFI-A-binding protein 2

1

0

High-throughput

0.493

High

124417

GLYR1
Cytokine-like nuclear factor N-PAC

1

0

High-throughput

0.493

High

124419

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

0

High-throughput

0.493

High

124428

EST1A
Telomerase-binding protein EST1A

1

0

High-throughput

0.493

High

124430

ARCH
Protein archease

1

0

High-throughput

0.493

High

124443

PEPL1
Probable aminopeptidase NPEPL1

1

0

High-throughput

0.493

High

124451

TET5B
Terminal nucleotidyltransferase 5B

1

0

High-throughput

0.493

High

124457

KAD8
Adenylate kinase 8

1

0

High-throughput

0.493

High

124459

DPYL5
Dihydropyrimidinase-related protein 5

1

0

High-throughput

0.493

High

124462

SHP1L
Testicular spindle-associated protein SHCBP1L

1

0

High-throughput

0.493

High

124464

ATG10
Ubiquitin-like-conjugating enzyme ATG10

1

0

High-throughput

0.493

High

124478

VPS54
Vacuolar protein sorting-associated protein 54

1

0

High-throughput

0.493

High

124479

SPMA2
Sperm microtubule associated protein 2

1

0

High-throughput

0.493

High

124482

JUPI1
Jupiter microtubule associated homolog 1

1

0

High-throughput

0.493

High

124483

OCTC
Peroxisomal carnitine O-octanoyltransferase

1

0

High-throughput

0.493

High

124484

NAGA
N-acetylglucosamine-6-phosphate deacetylase

1

0

High-throughput

0.493

High

124460

KXDL1
KxDL motif-containing protein 1

1

1

High-throughput

0.489

High

124413

ITSN1
Intersectin-1

1

6

High-throughput

0.481

High

124475

TBA8
Tubulin alpha-8 chain

1

1

High-throughput

0.481

High

124338

CTRO
Citron Rho-interacting kinase

1

11

High-throughput

0.479

High

124340

APAF
Apoptotic protease-activating factor 1

1

4

Small-scale

0.479

High

124345

STX6
Syntaxin-6

1

1

High-throughput

0.479

High

124348

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

124359

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.479

High

124362

PGFRB
Platelet-derived growth factor receptor beta

1

2

Small-scale

0.479

High

124367

CFTR
Cystic fibrosis transmembrane conductance regulator

1

14

High-throughput

0.479

High

124385

CASP9
Caspase-9

1

3

Small-scale

0.479

High

124387

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

11

High-throughput

0.479

High

124388

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

1

6

Small-scale

0.479

High

124389

H2B1D
Histone H2B type 1-D

1

18

High-throughput

0.479

High

124392

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

124393

AP2B1
AP-2 complex subunit beta

1

6

High-throughput

0.479

High

124421

A16L1
Autophagy-related protein 16-1

1

6

High-throughput

0.479

High

124425

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.479

High

124426

ATG9A
Autophagy-related protein 9A

1

3

High-throughput

0.479

High

124427

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

124435

RHG18
Rho GTPase-activating protein 18

1

3

High-throughput

0.479

High

124450

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

124466

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.479

High

124468

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

124477

BFAR
Bifunctional apoptosis regulator

1

7

Small-scale

0.479

High

124480

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

124381

RGR
RPE-retinal G protein-coupled receptor

1

4

High-throughput

0.470

High

124431

LRC56
Leucine-rich repeat-containing protein 56

1

9

High-throughput

0.470

High

124437

KLH36
Kelch-like protein 36

1

3

High-throughput

0.470

High

124441

WDR31
WD repeat-containing protein 31

1

7

High-throughput

0.470

High

124455

F167A
Protein FAM167A

1

2

High-throughput

0.470

High

124386

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.460

High

124446

SMAP2
Stromal membrane-associated protein 2

1

0

High-throughput

0.458

High

124350

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

4

High-throughput

0.445

High

124365

CALM3
Calmodulin-3

1

3

High-throughput

0.445

High

124368

VCAM1
Vascular cell adhesion protein 1

1

5

High-throughput

0.445

High

124373

BMI1
Polycomb complex protein BMI-1

1

3

High-throughput

0.445

High

124391

H2B1C
Histone H2B type 1-C/E/F/G/I

1

18

High-throughput

0.445

High

124403

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

17

High-throughput

0.445

High

124422

PKHA7
Pleckstrin homology domain-containing family A member 7

1

19

High-throughput

0.445

High

124463

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.445

High

124401

CENPR
Centromere protein R

1

0

High-throughput

0.438

High

124343

STX7
Syntaxin-7

1

4

High-throughput

0.437

High

124354

DIRA3
GTP-binding protein Di-Ras3

1

5

High-throughput

0.437

High

124434

CXD3
Gap junction delta-3 protein

1

7

High-throughput

0.437

High

124449

F168A
Protein FAM168A

2

0

High-throughput

0.316

High

124414

LPAL2
Putative apolipoprotein(a)-like protein 2

1

0

High-throughput

0.268

Low

124416

CC036
Uncharacterized protein C3orf36

1

0

High-throughput

0.268

Low

124418

ZC21C
Zinc finger C2HC domain-containing protein 1C

1

0

High-throughput

0.268

Low

124420

SPRY7
SPRY domain-containing protein 7

1

0

High-throughput

0.268

Low

124423

OGFD2
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2

1

0

High-throughput

0.268

Low

124432

FAM9A
Protein FAM9A

1

0

High-throughput

0.268

Low

124442

PRCA1
Protein PROCA1

1

0

High-throughput

0.268

Low

124429

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024