Protein: INT11
Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein) (Protein related to CPSF subunits of 68 kDa) (RC-68)

Gene: INT11, INTS11
Organism: Homo sapiens
Interactions: 94
UniProt ID: Q5TA45

Gene Ontology (top 5):
GO:0004521 - RNA endonuclease activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1135537

INT9
Integrator complex subunit 9

5

14

Small-scale

0.938

High

672157

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

2

1

High-throughput

0.811

High

1135522

INT4
Integrator complex subunit 4

2

3

Small-scale

0.776

High

930882

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

4

4

Small-scale

0.699

High

1075902

PCH2
Pachytene checkpoint protein 2 homolog

3

1

High-throughput

0.678

High

1135539

INT10
Integrator complex subunit 10

3

1

Small-scale

0.640

High

1135526

INT14
Integrator complex subunit 14

2

3

Small-scale

0.611

High

448692

RU1C
U1 small nuclear ribonucleoprotein C

2

1

High-throughput

0.606

High

973577

CREB5
Cyclic AMP-responsive element-binding protein 5

2

2

High-throughput

0.606

High

1081926

PKN1
Serine/threonine-protein kinase N1

2

2

High-throughput

0.606

High

1135514

SPIC
Transcription factor Spi-C

2

1

High-throughput

0.606

High

1135518

TFG
Protein TFG

2

2

High-throughput

0.606

High

1135525

LENG8
Leukocyte receptor cluster member 8

2

3

High-throughput

0.606

High

1135535

TF7L2
Transcription factor 7-like 2

2

4

High-throughput

0.606

High

1135538

INT13
Integrator complex subunit 13

2

3

Small-scale

0.594

High

1135506

INT3
Integrator complex subunit 3

2

1

Small-scale

0.584

High

1135541

INT6
Integrator complex subunit 6

2

1

Small-scale

0.584

High

211878

TLX3
T-cell leukemia homeobox protein 3

2

0

High-throughput

0.580

High

260312

PROP1
Homeobox protein prophet of Pit-1

2

0

High-throughput

0.580

High

271113

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

0

High-throughput

0.580

High

308098

VENTX
Homeobox protein VENTX

2

0

High-throughput

0.580

High

327898

TBX6
T-box transcription factor TBX6

2

0

High-throughput

0.580

High

686468

OTX1
Homeobox protein OTX1

2

0

High-throughput

0.580

High

997391

VAC14
Protein VAC14 homolog

2

0

High-throughput

0.580

High

1028173

GPS2
G protein pathway suppressor 2

2

0

High-throughput

0.580

High

1059989

LASP1
LIM and SH3 domain protein 1

2

0

High-throughput

0.580

High

1080592

ZIC1
Zinc finger protein ZIC 1

2

0

High-throughput

0.580

High

1109502

KR151
Keratin-associated protein 15-1

2

0

High-throughput

0.580

High

1135509

KR261
Keratin-associated protein 26-1

2

0

High-throughput

0.580

High

1135516

F222B
Protein FAM222B

2

0

High-throughput

0.580

High

1135523

ZC3HA
Zinc finger CCCH domain-containing protein 10

2

0

High-throughput

0.580

High

1135529

SPAG8
Sperm-associated antigen 8

2

0

High-throughput

0.580

High

1135542

HSF4
Heat shock factor protein 4

2

0

High-throughput

0.580

High

369782

ESR1
Estrogen receptor

2

7

High-throughput

0.571

High

893561

SEM1
26S proteasome complex subunit SEM1

2

1

Small-scale

0.571

High

1135515

OXER1
Oxoeicosanoid receptor 1

2

1

High-throughput

0.553

High

1135536

PLS4
Phospholipid scramblase 4

2

1

High-throughput

0.553

High

170088

PLS1
Phospholipid scramblase 1

1

1

High-throughput

0.541

High

1135511

NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor

1

0

Small-scale

0.537

High

123969

SPT5H
Transcription elongation factor SPT5

1

2

High-throughput

0.536

High

323816

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

574367

RL35A
Large ribosomal subunit protein eL33

1

1

High-throughput

0.536

High

583723

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

1

High-throughput

0.536

High

676904

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

2

High-throughput

0.536

High

738847

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

1

High-throughput

0.536

High

818136

SOX2
Transcription factor SOX-2

1

4

High-throughput

0.536

High

851532

NEK4
Serine/threonine-protein kinase Nek4

1

1

High-throughput

0.536

High

853618

IMA5
Importin subunit alpha-5

1

3

High-throughput

0.536

High

864949

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

1

High-throughput

0.536

High

897536

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

1

High-throughput

0.536

High

915213

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

4

High-throughput

0.536

High

996704

SSRP1
FACT complex subunit SSRP1

1

3

High-throughput

0.536

High

1087179

H2B2E
Histone H2B type 2-E

1

2

High-throughput

0.536

High

1135520

SOSB2
SOSS complex subunit B2

1

2

High-throughput

0.536

High

1135530

SOSB1
SOSS complex subunit B1

1

2

High-throughput

0.536

High

1135534

ENY2
Transcription and mRNA export factor ENY2

1

1

High-throughput

0.536

High

1135528

MDFI
MyoD family inhibitor

1

0

High-throughput

0.518

High

400328

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.513

High

1028315

NDK3
Nucleoside diphosphate kinase 3

1

0

High-throughput

0.513

High

1135510

RAD9B
Cell cycle checkpoint control protein RAD9B

1

0

High-throughput

0.513

High

1135532

COMD5
COMM domain-containing protein 5

1

0

High-throughput

0.513

High

861789

PLK1
Serine/threonine-protein kinase PLK1

1

1

High-throughput

0.508

High

1135524

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.489

High

1135527

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.489

High

378712

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.486

High

589203

ANXA7
Annexin A7

1

0

High-throughput

0.486

High

931677

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.486

High

227710

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

322739

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

347009

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.479

High

374368

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

455535

PARP1
Poly [ADP-ribose] polymerase 1

1

4

High-throughput

0.479

High

624924

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

4

Small-scale

0.479

High

779565

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

917409

H4
Histone H4

1

5

High-throughput

0.479

High

1041760

CUL3
Cullin-3

1

2

High-throughput

0.479

High

1135508

INT5
Integrator complex subunit 5

1

3

High-throughput

0.479

High

1135513

INT1
Integrator complex subunit 1

1

3

High-throughput

0.479

High

1135517

ESR2
Estrogen receptor beta

1

7

High-throughput

0.479

High

319226

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.458

High

1029515

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1135531

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

0

High-throughput

0.458

High

1135533

INT2
Integrator complex subunit 2

1

0

Small-scale

0.458

High

1135512

SEML
Putative protein SEM1, isoform 2

1

1

High-throughput

0.437

High

474614

PRR35
Proline-rich protein 35

2

0

High-throughput

0.316

High

1135507

CA094
Uncharacterized protein C1orf94

2

0

High-throughput

0.316

High

1135521

CC120
Coiled-coil domain-containing protein 120

2

0

High-throughput

0.316

High

1135540

DSE
Dermatan-sulfate epimerase

1

0

High-throughput

0.282

High

319572

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.279

Low

1100053

INF2
Inverted formin-2

1

0

High-throughput

0.279

Low

1135519

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

0

High-throughput

0.279

Low

1135543

DHDH
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

1

0

High-throughput

0.279

Low

898031

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.251

Low

832849

TSP3
Thrombospondin-3

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024