Protein: INT6
Integrator complex subunit 6 (Int6) (DBI-1) (Protein DDX26) (Protein deleted in cancer 1) (DICE1)

Gene: INT6, INTS6
Organism: Homo sapiens
Interactions: 101
UniProt ID: Q9UL03

Gene Ontology (top 5):
GO:0004888 - transmembrane signaling receptor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0015629 - actin cytoskeleton
GO:0016180 - snRNA processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

931037

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

5

4

Small-scale

0.927

High

915302

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

3

4

Small-scale

0.847

High

1302607

INT14
Integrator complex subunit 14

2

0

High-throughput

0.748

High

1148344

INT3
Integrator complex subunit 3

6

2

Small-scale

0.740

High

1346751

INT13
Integrator complex subunit 13

2

0

Small-scale

0.716

High

672344

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

4

3

Small-scale

0.697

High

150009

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

3

2

High-throughput

0.667

High

583839

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

3

1

Small-scale

0.656

High

677052

RPB2
DNA-directed RNA polymerase II subunit RPB2

3

1

Small-scale

0.656

High

1308832

SOSB1
SOSS complex subunit B1

3

2

Small-scale

0.656

High

583626

RPB3
DNA-directed RNA polymerase II subunit RPB3

4

0

Small-scale

0.651

High

1166188

OLFM4
Olfactomedin-4

3

0

High-throughput

0.638

High

1309168

TBL1Y
F-box-like/WD repeat-containing protein TBL1Y

2

1

High-throughput

0.628

High

738116

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

3

Small-scale

0.618

High

906627

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

3

High-throughput

0.618

High

1127517

INT6L
Integrator complex subunit 6-like

1

3

High-throughput

0.618

High

1346817

INT10
Integrator complex subunit 10

3

0

Small-scale

0.613

High

992723

LRP1
Prolow-density lipoprotein receptor-related protein 1

2

0

High-throughput

0.602

High

1219976

BBS7
Bardet-Biedl syndrome 7 protein

2

0

High-throughput

0.602

High

625092

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

1

Small-scale

0.584

High

672491

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

2

3

Small-scale

0.584

High

1135541

INT11
Integrator complex subunit 11

2

1

Small-scale

0.584

High

1160543

INT5
Integrator complex subunit 5

2

1

Small-scale

0.584

High

1175989

INT8
Integrator complex subunit 8

2

1

Small-scale

0.584

High

1231133

INT1
Integrator complex subunit 1

2

2

Small-scale

0.584

High

1327764

INT2
Integrator complex subunit 2

2

1

Small-scale

0.584

High

1346372

INT9
Integrator complex subunit 9

2

1

Small-scale

0.584

High

1346577

INT7
Integrator complex subunit 7

2

1

Small-scale

0.584

High

370682

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

709108

MCM7
DNA replication licensing factor MCM7

1

0

Small-scale

0.569

High

1286603

INT12
Integrator complex subunit 12

2

0

Small-scale

0.559

High

1293898

INT4
Integrator complex subunit 4

2

0

Small-scale

0.559

High

893618

SEM1
26S proteasome complex subunit SEM1

2

0

Small-scale

0.547

High

124122

SPT5H
Transcription elongation factor SPT5

1

4

High-throughput

0.536

High

380878

S100B
Protein S100-B

1

6

High-throughput

0.536

High

416727

S10A6
Protein S100-A6

1

6

High-throughput

0.536

High

639123

S100P
Protein S100-P

1

6

High-throughput

0.536

High

865014

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

1

High-throughput

0.536

High

897661

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

1

High-throughput

0.536

High

996951

SSRP1
FACT complex subunit SSRP1

1

1

High-throughput

0.536

High

1087474

H2B2E
Histone H2B type 2-E

1

2

High-throughput

0.536

High

1271115

EZH1
Histone-lysine N-methyltransferase EZH1

1

1

High-throughput

0.536

High

1284208

SOSB2
SOSS complex subunit B2

1

2

High-throughput

0.536

High

508769

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

666992

TKT
Transketolase

1

0

High-throughput

0.513

High

855328

STAT2
Signal transducer and activator of transcription 2

1

0

High-throughput

0.513

High

887632

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

1303844

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

1356685

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

2

Small-scale

0.501

High

558798

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

1

High-throughput

0.489

High

608256

KCNA4
Potassium voltage-gated channel subfamily A member 4

1

1

High-throughput

0.489

High

661477

S10A2
Protein S100-A2

1

6

High-throughput

0.489

High

1238129

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

3

High-throughput

0.489

High

1356683

ANR50
Ankyrin repeat domain-containing protein 50

1

2

High-throughput

0.489

High

669067

PML
Protein PML

1

1

High-throughput

0.479

High

718298

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.479

High

877944

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.479

High

1069913

PTPA
Serine/threonine-protein phosphatase 2A activator

1

1

Small-scale

0.479

High

1230899

ZN687
Zinc finger protein 687

1

1

High-throughput

0.479

High

1262839

PHIP
PH-interacting protein

1

2

High-throughput

0.479

High

1267975

ZN592
Zinc finger protein 592

1

1

High-throughput

0.479

High

1269902

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1356684

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

1

High-throughput

0.479

High

181482

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.458

High

182951

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

539183

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.458

High

554030

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

652578

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

721753

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

727091

FUS
RNA-binding protein FUS

1

0

High-throughput

0.458

High

841533

KNTC1
Kinetochore-associated protein 1

1

0

High-throughput

0.458

High

854395

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.458

High

854496

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

1

0

High-throughput

0.458

High

913981

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

0

High-throughput

0.458

High

918124

H4
Histone H4

1

0

High-throughput

0.458

High

921193

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.458

High

1042819

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1148595

NAIF1
Nuclear apoptosis-inducing factor 1

1

0

High-throughput

0.458

High

1189024

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1272395

RENT1
Regulator of nonsense transcripts 1

1

0

Small-scale

0.458

High

1298361

INT15
Integrator complex subunit 15

1

0

High-throughput

0.458

High

1334899

RENT2
Regulator of nonsense transcripts 2

1

0

Small-scale

0.458

High

1348907

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1354819

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1049676

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

1

Small-scale

0.445

High

1233257

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.445

High

1172220

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

135302

E2F3
Transcription factor E2F3

1

0

Small-scale

0.426

High

417043

IF4E
Eukaryotic translation initiation factor 4E

1

0

Small-scale

0.426

High

980022

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

0

Small-scale

0.426

High

998214

NCBP1
Nuclear cap-binding protein subunit 1

1

0

Small-scale

0.426

High

1044262

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.426

High

1149877

SCAR3
Scavenger receptor class A member 3

3

0

High-throughput

0.347

High

612126

PROZ
Vitamin K-dependent protein Z

2

0

High-throughput

0.328

High

159687

QCR10
Cytochrome b-c1 complex subunit 10

1

0

High-throughput

0.279

Low

1136854

FAXC
Failed axon connections homolog

1

0

High-throughput

0.279

Low

1231428

CT197
Putative uncharacterized protein encoded by LINC02910

1

0

High-throughput

0.279

Low

1253279

ADA32
Disintegrin and metalloproteinase domain-containing protein 32

1

0

High-throughput

0.279

Low

385701

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

1173054

SEML
Putative protein SEM1, isoform 2

1

0

High-throughput

0.249

Low

1331602

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024