Protein: CASP7
Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (CMH-1) (ICE-like apoptotic protease 3) (ICE-LAP3) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11]

Gene: CASP7
Organism: Homo sapiens
Interactions: 67
UniProt ID: P55210

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004190 - aspartic-type endopeptidase activity
GO:0004197 - cysteine-type endopeptidase activity
GO:0005615 - extracellular space
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

876939

XIAP
E3 ubiquitin-protein ligase XIAP

18

20

Small-scale

0.989

High

876945

BIRC2
Baculoviral IAP repeat-containing protein 2

6

20

Small-scale

0.949

High

876964

BIRC6
Baculoviral IAP repeat-containing protein 6

4

20

Small-scale

0.906

High

876944

BIRC3
Baculoviral IAP repeat-containing protein 3

3

20

Small-scale

0.834

High

876934

CASP9
Caspase-9

2

19

Small-scale

0.812

High

177663

BIRC5
Baculoviral IAP repeat-containing protein 5

2

20

Small-scale

0.799

High

876948

CASP8
Caspase-8

2

19

Small-scale

0.778

High

876933

CASP7
Caspase-7

2

19

Small-scale

0.768

High

486157

GRAB
Granzyme B

4

11

Small-scale

0.699

High

876935

CASP6
Caspase-6

1

19

Small-scale

0.692

High

455268

PARP1
Poly [ADP-ribose] polymerase 1

3

9

Small-scale

0.672

High

876949

TEBP
Prostaglandin E synthase 3

3

3

Small-scale

0.672

High

788169

CASP3
Caspase-3

1

18

Small-scale

0.647

High

788239

CASP2
Caspase-2

1

20

Small-scale

0.647

High

876959

CASPA
Caspase-10

1

19

Small-scale

0.647

High

876960

BIRC7
Baculoviral IAP repeat-containing protein 7

1

20

Small-scale

0.647

High

600007

SAT1
Diamine acetyltransferase 1

3

0

High-throughput

0.646

High

876966

FBW1B
F-box/WD repeat-containing protein 11

2

4

High-throughput

0.611

High

796260

MAGAB
Melanoma-associated antigen 11

2

1

High-throughput

0.606

High

414222

RB
Retinoblastoma-associated protein

2

5

Small-scale

0.602

High

854754

GDIR1
Rho GDP-dissociation inhibitor 1

2

8

Small-scale

0.602

High

876938

HTRA4
Serine protease HTRA4

1

2

High-throughput

0.597

High

358991

CRYAB
Alpha-crystallin B chain

2

10

Small-scale

0.584

High

501879

BIP
Endoplasmic reticulum chaperone BiP

2

6

Small-scale

0.584

High

876951

NF2L2
Nuclear factor erythroid 2-related factor 2

1

3

Small-scale

0.582

High

876962

NIF3L
NIF3-like protein 1

2

0

High-throughput

0.580

High

876941

PAK2
Serine/threonine-protein kinase PAK 2

1

6

Small-scale

0.578

High

876961

PANX1
Pannexin-1

2

2

Small-scale

0.564

High

869586

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.541

High

876936

TCPB
T-complex protein 1 subunit beta

1

0

Small-scale

0.537

High

854844

GDIR2
Rho GDP-dissociation inhibitor 2

1

8

Small-scale

0.536

High

812813

PA24A
Cytosolic phospholipase A2

1

7

Small-scale

0.536

High

567443

ASM
Sphingomyelin phosphodiesterase

1

1

Small-scale

0.536

High

876940

TRAF2
TNF receptor-associated factor 2

1

19

High-throughput

0.536

High

876952

C2D1B
Coiled-coil and C2 domain-containing protein 1B

1

1

High-throughput

0.536

High

876967

FBW1A
F-box/WD repeat-containing protein 1A

1

4

High-throughput

0.536

High

655286

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

4

High-throughput

0.515

High

791419

HD
Huntingtin

1

4

High-throughput

0.515

High

876955

SKAP1
Src kinase-associated phosphoprotein 1

1

2

High-throughput

0.515

High

876957

SLAI1
SLAIN motif-containing protein 1

1

0

High-throughput

0.513

High

124292

DFFA
DNA fragmentation factor subunit alpha

1

3

Small-scale

0.501

High

321313

IL33
Interleukin-33

1

2

Small-scale

0.501

High

338192

EGFR
Epidermal growth factor receptor

1

6

Small-scale

0.501

High

435022

SP1
Transcription factor Sp1

1

2

Small-scale

0.501

High

439327

CATG
Cathepsin G

1

10

Small-scale

0.501

High

443427

VIME
Vimentin

1

5

Small-scale

0.501

High

473775

PA24B
Cytosolic phospholipase A2 beta

1

7

Small-scale

0.501

High

496654

TAU
Microtubule-associated protein tau

1

7

Small-scale

0.501

High

584355

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

16

Small-scale

0.501

High

786287

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

2

Small-scale

0.501

High

876937

NUCB2
Nucleobindin-2

1

5

Small-scale

0.501

High

876943

ROCK1
Rho-associated protein kinase 1

1

4

Small-scale

0.501

High

876946

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

2

Small-scale

0.501

High

876954

CSN6
COP9 signalosome complex subunit 6

1

5

Small-scale

0.501

High

876958

HDAC7
Histone deacetylase 7

1

6

Small-scale

0.501

High

876963

CLSPN
Claspin

1

3

Small-scale

0.501

High

876942

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.493

High

386390

P53
Cellular tumor antigen p53

1

5

High-throughput

0.479

High

575350

EGR1
Early growth response protein 1

1

1

High-throughput

0.479

High

868098

ATX3
Ataxin-3

1

2

High-throughput

0.479

High

874728

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.479

High

876947

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

4

High-throughput

0.479

High

876950

NEDD8
NEDD8

1

2

Small-scale

0.479

High

876953

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.479

High

876965

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

876956

KLH36
Kelch-like protein 36

1

3

High-throughput

0.470

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024