Protein: HTRA1
Serine protease HTRA1 (EC 3.4.21.-) (High-temperature requirement A serine peptidase 1) (L56) (Serine protease 11)

Gene: HTRA1
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q92743

Gene Ontology (top 5):
GO:0001890 - placenta development
GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1270189

HTRA1
Serine protease HTRA1

5

17

Small-scale

0.937

High

949037

HTRA4
Serine protease HTRA4

1

15

Small-scale

0.724

High

1205539

TMM25
Transmembrane protein 25

3

1

High-throughput

0.667

High

497378

TAU
Microtubule-associated protein tau

3

0

Small-scale

0.649

High

957747

XIAP
E3 ubiquitin-protein ligase XIAP

2

15

Small-scale

0.629

High

965257

DEF5
Defensin alpha 5

2

1

High-throughput

0.628

High

1270193

REG4
Regenerating islet-derived protein 4

2

2

High-throughput

0.628

High

237370

ISK4
Serine protease inhibitor Kazal-type 4

2

0

High-throughput

0.602

High

351582

NEU2
Vasopressin-neurophysin 2-copeptin

2

0

High-throughput

0.602

High

585613

FUT1
Galactoside alpha-(1,2)-fucosyltransferase 1

2

0

High-throughput

0.602

High

1270194

DB127
Beta-defensin 127

2

0

High-throughput

0.602

High

151113

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.586

High

1059027

LTBP1
Latent-transforming growth factor beta-binding protein 1

1

9

Small-scale

0.536

High

685279

CEAM8
Carcinoembryonic antigen-related cell adhesion molecule 8

1

1

High-throughput

0.536

High

1270197

OPT
Opticin

1

5

High-throughput

0.536

High

535897

MIF
Macrophage migration inhibitory factor

1

0

Small-scale

0.529

High

435962

MSMB
Beta-microseminoprotein

1

0

High-throughput

0.513

High

1029191

NOGG
Noggin

1

0

High-throughput

0.513

High

1166320

ALKL2
ALK and LTK ligand 2

1

0

High-throughput

0.513

High

1239225

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.513

High

1270199

DKKL1
Dickkopf-like protein 1

1

0

High-throughput

0.513

High

1270202

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

434662

TSP1
Thrombospondin-1

1

2

Small-scale

0.501

High

1016979

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

1

10

Small-scale

0.501

High

667714

NOS3
Nitric oxide synthase 3

1

0

High-throughput

0.486

High

931774

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.481

High

395368

A4
Amyloid-beta precursor protein

1

0

Small-scale

0.480

High

1075350

BGH3
Transforming growth factor-beta-induced protein ig-h3

1

0

Small-scale

0.480

High

205780

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

908904

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

944123

JAG1
Protein jagged-1

1

3

Small-scale

0.479

High

361509

APOE
Apolipoprotein E

1

0

High-throughput

0.460

High

596080

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

1

0

High-throughput

0.460

High

124916

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

1

Small-scale

0.457

High

358545

CO1A1
Collagen alpha-1(I) chain

1

1

Small-scale

0.457

High

612892

FBLN1
Fibulin-1

1

10

Small-scale

0.457

High

894280

CDC42
Cell division control protein 42 homolog

1

1

Small-scale

0.457

High

1046532

TBB2A
Tubulin beta-2A chain

1

4

Small-scale

0.457

High

1270191

LZTS2
Leucine zipper putative tumor suppressor 2

1

2

Small-scale

0.457

High

1270200

ATS7
A disintegrin and metalloproteinase with thrombospondin motifs 7

1

2

Small-scale

0.457

High

882472

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.445

High

1270190

TET5A
Terminal nucleotidyltransferase 5A

1

1

High-throughput

0.439

High

835092

TSC2
Tuberin

1

0

Small-scale

0.438

High

1270201

CTND2
Catenin delta-2

1

0

Small-scale

0.438

High

1171065

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

1270196

SP110
Sp110 nuclear body protein

1

1

High-throughput

0.437

High

924739

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.426

High

335845

COX2
Cytochrome c oxidase subunit 2

1

1

Small-scale

0.417

High

850537

DYLT3
Dynein light chain Tctex-type 3

1

1

Small-scale

0.417

High

1136783

Q5TF85
polynucleotide adenylyltransferase

1

1

High-throughput

0.417

High

1073457

KS6A1
Ribosomal protein S6 kinase alpha-1

1

0

Small-scale

0.391

High

1270195

SPRNG
SREBP regulating gene protein

2

0

High-throughput

0.328

High

1270198

MGT4C
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C

2

0

High-throughput

0.328

High

329181

F107A
Actin-associated protein FAM107A

1

0

Small-scale

0.251

Low

244724

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.249

Low

600198

TAF1
Transcription initiation factor TFIID subunit 1

1

0

High-throughput

0.249

Low

1080184

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

1176232

B4GN4
N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1

1

0

Small-scale

0.238

Low

1270192

WAC
WW domain-containing adapter protein with coiled-coil

1

0

Small-scale

0.238

Low


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Last updated: 15 Jul 2024