Download interactions: TXT MITAB-2.5
| Interaction | Interactor | Experiments | Homologs | Category | Interaction Score |
Confidence |
|---|---|---|---|---|---|---|
|
P63
Tumor protein 63 |
7 |
14 |
Small-scale |
0.960 | High |
|
|
P53
Cellular tumor antigen p53 |
7 |
14 |
Small-scale |
0.959 | High |
|
|
P73
Tumor protein p73 |
5 |
14 |
Small-scale |
0.933 | High |
|
|
ABL1
Tyrosine-protein kinase ABL1 |
5 |
5 |
Small-scale |
0.924 | High |
|
|
MDM2
E3 ubiquitin-protein ligase Mdm2 |
13 |
10 |
Small-scale |
0.763 | High |
|
|
YAP1
Transcriptional coactivator YAP1 |
11 |
20 |
Small-scale |
0.757 | High |
|
|
EP300
Histone acetyltransferase p300 |
8 |
20 |
Small-scale |
0.755 | High |
|
|
HCK
Tyrosine-protein kinase HCK |
1 |
5 |
Small-scale |
0.747 | High |
|
|
ITCH
E3 ubiquitin-protein ligase Itchy homolog |
6 |
15 |
Small-scale |
0.743 | High |
|
|
MDM4
Protein Mdm4 |
6 |
10 |
Small-scale |
0.732 | High |
|
|
ASPP1
Apoptosis-stimulating of p53 protein 1 |
1 |
16 |
Small-scale |
0.681 | High |
|
|
WWOX
WW domain-containing oxidoreductase |
3 |
5 |
Small-scale |
0.678 | High |
|
|
NEDD4
E3 ubiquitin-protein ligase NEDD4 |
3 |
15 |
Small-scale |
0.660 | High |
|
|
DAXX
Death domain-associated protein 6 |
2 |
4 |
Small-scale |
0.649 | High |
|
|
ASPP2
Apoptosis-stimulating of p53 protein 2 |
1 |
17 |
Small-scale |
0.647 | High |
|
|
IASPP
RelA-associated inhibitor |
1 |
14 |
Small-scale |
0.647 | High |
|
|
IER2
Immediate early response gene 2 protein |
3 |
0 |
High-throughput |
0.638 | High |
|
|
WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2 |
2 |
15 |
Small-scale |
0.634 | High |
|
|
KPCD
Protein kinase C delta type |
2 |
4 |
Small-scale |
0.634 | High |
|
|
ZN363
RING finger and CHY zinc finger domain-containing protein 1 |
2 |
3 |
Small-scale |
0.634 | High |
|
|
TDG
G/T mismatch-specific thymine DNA glycosylase |
2 |
2 |
Small-scale |
0.633 | High |
|
|
KAT2B
Histone acetyltransferase KAT2B |
2 |
15 |
Small-scale |
0.631 | High |
|
|
SKP2
S-phase kinase-associated protein 2 |
2 |
2 |
High-throughput |
0.628 | High |
|
|
LMBL1
Lethal(3)malignant brain tumor-like protein 1 |
2 |
2 |
High-throughput |
0.628 | High |
|
|
IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha |
2 |
10 |
Small-scale |
0.624 | High |
|
|
MYC
Myc proto-oncogene protein |
2 |
5 |
Small-scale |
0.624 | High |
|
|
HDAC1
Histone deacetylase 1 |
2 |
7 |
Small-scale |
0.624 | High |
|
|
AURKA
Aurora kinase A |
1 |
5 |
Small-scale |
0.619 | High |
|
|
TP53B
TP53-binding protein 1 |
1 |
7 |
High-throughput |
0.618 | High |
|
|
SOCS1
Suppressor of cytokine signaling 1 |
2 |
3 |
Small-scale |
0.611 | High |
|
|
MLF1
Myeloid leukemia factor 1 |
2 |
1 |
High-throughput |
0.611 | High |
|
|
ANM6
Protein arginine N-methyltransferase 6 |
2 |
6 |
High-throughput |
0.611 | High |
|
|
CBP
CREB-binding protein |
2 |
17 |
Small-scale |
0.602 | High |
|
|
SIR1
NAD-dependent protein deacetylase sirtuin-1 |
1 |
5 |
Small-scale |
0.596 | High |
|
|
PMS2
Mismatch repair endonuclease PMS2 |
2 |
2 |
Small-scale |
0.594 | High |
|
|
CEBPZ
CCAAT/enhancer-binding protein zeta |
1 |
1 |
Small-scale |
0.589 | High |
|
|
DSN1
Kinetochore-associated protein DSN1 homolog |
2 |
0 |
High-throughput |
0.585 | High |
|
|
NFYB
Nuclear transcription factor Y subunit beta |
2 |
1 |
Small-scale |
0.584 | High |
|
|
IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta |
1 |
9 |
Small-scale |
0.578 | High |
|
|
PIAS1
E3 SUMO-protein ligase PIAS1 |
1 |
10 |
Small-scale |
0.578 | High |
|
|
CDK1
Cyclin-dependent kinase 1 |
1 |
5 |
Small-scale |
0.578 | High |
|
|
CCNA2
Cyclin-A2 |
1 |
3 |
Small-scale |
0.578 | High |
|
|
PLK1
Serine/threonine-protein kinase PLK1 |
1 |
7 |
Small-scale |
0.578 | High |
|
|
CHIP
E3 ubiquitin-protein ligase CHIP |
1 |
4 |
Small-scale |
0.578 | High |
|
|
KAPCB
cAMP-dependent protein kinase catalytic subunit beta |
1 |
2 |
Small-scale |
0.573 | High |
|
|
RACK1
Small ribosomal subunit protein RACK1 |
1 |
6 |
Small-scale |
0.573 | High |
|
|
GRP75
Stress-70 protein, mitochondrial |
1 |
10 |
Small-scale |
0.573 | High |
|
|
BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta |
1 |
5 |
Small-scale |
0.561 | High |
|
|
FBSP1
F-box/SPRY domain-containing protein 1 |
1 |
6 |
Small-scale |
0.561 | High |
|
|
ATF3
Cyclic AMP-dependent transcription factor ATF-3 |
1 |
6 |
Small-scale |
0.561 | High |
|
|
RL5
Large ribosomal subunit protein uL18 |
1 |
1 |
Small-scale |
0.561 | High |
|
|
RL11
Large ribosomal subunit protein uL5 |
1 |
2 |
Small-scale |
0.561 | High |
|
|
CSK21
Casein kinase II subunit alpha |
1 |
9 |
Small-scale |
0.561 | High |
|
|
TIF1B
Transcription intermediary factor 1-beta |
1 |
15 |
Small-scale |
0.561 | High |
|
|
PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
1 |
3 |
Small-scale |
0.561 | High |
|
|
DDB1
DNA damage-binding protein 1 |
1 |
3 |
Small-scale |
0.561 | High |
|
|
MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1 |
1 |
5 |
Small-scale |
0.561 | High |
|
|
RANB9
Ran-binding protein 9 |
1 |
6 |
Small-scale |
0.561 | High |
|
|
PLAL1
Zinc finger protein PLAGL1 |
1 |
7 |
Small-scale |
0.561 | High |
|
|
NFYC
Nuclear transcription factor Y subunit gamma |
2 |
0 |
Small-scale |
0.559 | High |
|
|
AMPH
Amphiphysin |
1 |
4 |
Small-scale |
0.552 | High |
|
|
PFD5
Prefoldin subunit 5 |
1 |
0 |
Small-scale |
0.549 | High |
|
|
CCNE1
G1/S-specific cyclin-E1 |
1 |
4 |
Small-scale |
0.536 | High |
|
|
SOX2
Transcription factor SOX-2 |
1 |
10 |
High-throughput |
0.536 | High |
|
|
CDC20
Cell division cycle protein 20 homolog |
1 |
7 |
Small-scale |
0.536 | High |
|
|
MD2L1
Mitotic spindle assembly checkpoint protein MAD2A |
1 |
1 |
Small-scale |
0.536 | High |
|
|
HASP
Serine/threonine-protein kinase haspin |
1 |
1 |
High-throughput |
0.536 | High |
|
|
WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1 |
1 |
15 |
High-throughput |
0.536 | High |
|
|
HSPB8
Heat shock protein beta-8 |
1 |
5 |
High-throughput |
0.536 | High |
|
|
HMGB1
High mobility group protein B1 |
1 |
9 |
Small-scale |
0.527 | High |
|
|
FLNA
Filamin-A |
1 |
5 |
Small-scale |
0.527 | High |
|
|
CCNT1
Cyclin-T1 |
1 |
9 |
Small-scale |
0.515 | High |
|
|
CNDH2
Condensin-2 complex subunit H2 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
HECW2
E3 ubiquitin-protein ligase HECW2 |
1 |
15 |
Small-scale |
0.512 | High |
|
|
SP1
Transcription factor Sp1 |
1 |
6 |
Small-scale |
0.501 | High |
|
|
CCNB1
G2/mitotic-specific cyclin-B1 |
1 |
3 |
Small-scale |
0.501 | High |
|
|
CCND1
G1/S-specific cyclin-D1 |
1 |
6 |
Small-scale |
0.501 | High |
|
|
CDK2
Cyclin-dependent kinase 2 |
1 |
6 |
Small-scale |
0.501 | High |
|
|
SP3
Transcription factor Sp3 |
1 |
10 |
Small-scale |
0.501 | High |
|
|
PRLD2
PRELI domain-containing protein 2 |
1 |
1 |
High-throughput |
0.489 | High |
|
|
SUMO1
Small ubiquitin-related modifier 1 |
1 |
6 |
Small-scale |
0.481 | High |
|
|
UBC9
SUMO-conjugating enzyme UBC9 |
1 |
8 |
Small-scale |
0.481 | High |
|
|
CHD3
Chromodomain-helicase-DNA-binding protein 3 |
1 |
6 |
Small-scale |
0.481 | High |
|
|
HIPK2
Homeodomain-interacting protein kinase 2 |
1 |
15 |
Small-scale |
0.481 | High |
|
|
HIPK3
Homeodomain-interacting protein kinase 3 |
1 |
17 |
Small-scale |
0.481 | High |
|
|
TRI66
Tripartite motif-containing protein 66 |
1 |
16 |
High-throughput |
0.479 | High |
|
|
KDM1A
Lysine-specific histone demethylase 1A |
1 |
2 |
Small-scale |
0.479 | High |
|
|
DNJB6
DnaJ homolog subfamily B member 6 |
1 |
6 |
High-throughput |
0.479 | High |
|
|
UBE4B
Ubiquitin conjugation factor E4 B |
1 |
7 |
Small-scale |
0.479 | High |
|
|
DRC4
Dynein regulatory complex subunit 4 |
1 |
2 |
High-throughput |
0.479 | High |
|
|
JUN
Transcription factor Jun |
1 |
4 |
Small-scale |
0.479 | High |
|
|
RB
Retinoblastoma-associated protein |
1 |
3 |
Small-scale |
0.479 | High |
|
|
TPM3
Tropomyosin alpha-3 chain |
1 |
4 |
High-throughput |
0.479 | High |
|
|
UBC
Polyubiquitin-C [Cleaved into: Ubiquitin] |
1 |
6 |
Small-scale |
0.479 | High |
|
|
ADHX
Alcohol dehydrogenase class-3 |
1 |
3 |
High-throughput |
0.479 | High |
|
|
ETS2
Protein C-ets-2 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
KAPCA
cAMP-dependent protein kinase catalytic subunit alpha |
1 |
2 |
Small-scale |
0.479 | High |
|
|
SAHH
Adenosylhomocysteinase |
1 |
3 |
High-throughput |
0.479 | High |
|
|
MYL9
Myosin regulatory light polypeptide 9 |
1 |
5 |
High-throughput |
0.479 | High |
|
|
PAX6
Paired box protein Pax-6 |
1 |
3 |
High-throughput |
0.479 | High |
|
|
HSP74
Heat shock 70 kDa protein 4 |
1 |
11 |
Small-scale |
0.479 | High |
|
|
FUS
RNA-binding protein FUS |
1 |
10 |
High-throughput |
0.479 | High |
|
|
BRCA1
Breast cancer type 1 susceptibility protein |
1 |
12 |
Small-scale |
0.479 | High |
|
|
CDN1A
Cyclin-dependent kinase inhibitor 1 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
STAT1
Signal transducer and activator of transcription 1-alpha/beta |
1 |
3 |
Small-scale |
0.479 | High |
|
|
LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial |
1 |
2 |
High-throughput |
0.479 | High |
|
|
MAGA2
Melanoma-associated antigen 2 |
1 |
8 |
Small-scale |
0.479 | High |
|
|
CCNG1
Cyclin-G1 |
1 |
8 |
Small-scale |
0.479 | High |
|
|
RS14
Small ribosomal subunit protein uS11 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
ACK1
Activated CDC42 kinase 1 |
1 |
12 |
Small-scale |
0.479 | High |
|
|
TRI32
E3 ubiquitin-protein ligase TRIM32 |
1 |
10 |
Small-scale |
0.479 | High |
|
|
CUL1
Cullin-1 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
RUNX2
Runt-related transcription factor 2 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
HIF1A
Hypoxia-inducible factor 1-alpha |
1 |
7 |
Small-scale |
0.479 | High |
|
|
CBPC2
Cytosolic carboxypeptidase 2 |
1 |
4 |
High-throughput |
0.479 | High |
|
|
DAB2P
Disabled homolog 2-interacting protein |
1 |
4 |
High-throughput |
0.479 | High |
|
|
TTLL5
Tubulin polyglutamylase TTLL5 |
1 |
4 |
High-throughput |
0.479 | High |
|
|
TPC11
Trafficking protein particle complex subunit 11 |
1 |
3 |
High-throughput |
0.479 | High |
|
|
R144B
E3 ubiquitin-protein ligase RNF144B |
1 |
6 |
Small-scale |
0.479 | High |
|
|
N4BP2
NEDD4-binding protein 2 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
SIAH1
E3 ubiquitin-protein ligase SIAH1 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
ASPM
Abnormal spindle-like microcephaly-associated protein |
1 |
10 |
High-throughput |
0.479 | High |
|
|
STAG1
Cohesin subunit SA-1 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
TOPB1
DNA topoisomerase 2-binding protein 1 |
1 |
6 |
Small-scale |
0.479 | High |
|
|
AKAP1
A-kinase anchor protein 1, mitochondrial |
1 |
5 |
High-throughput |
0.479 | High |
|
|
HDAC2
Histone deacetylase 2 |
1 |
7 |
Small-scale |
0.479 | High |
|
|
SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 |
1 |
6 |
High-throughput |
0.479 | High |
|
|
KAT5
Histone acetyltransferase KAT5 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
SPSB1
SPRY domain-containing SOCS box protein 1 |
1 |
8 |
High-throughput |
0.479 | High |
|
|
PIWL1
Piwi-like protein 1 |
1 |
10 |
High-throughput |
0.479 | High |
|
|
CIC
Protein capicua homolog |
1 |
15 |
High-throughput |
0.479 | High |
|
|
MED15
Mediator of RNA polymerase II transcription subunit 15 |
1 |
13 |
Small-scale |
0.479 | High |
|
|
DDX23
Probable ATP-dependent RNA helicase DDX23 |
1 |
5 |
High-throughput |
0.479 | High |
|
|
DPH1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 |
1 |
3 |
High-throughput |
0.479 | High |
|
|
BRD8
Bromodomain-containing protein 8 |
1 |
20 |
High-throughput |
0.479 | High |
|
|
RNF38
E3 ubiquitin-protein ligase RNF38 |
1 |
7 |
High-throughput |
0.479 | High |
|
|
CDT1
DNA replication factor Cdt1 |
1 |
2 |
High-throughput |
0.479 | High |
|
|
JPH1
Junctophilin-1 |
1 |
2 |
High-throughput |
0.479 | High |
|
|
IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1 |
1 |
7 |
High-throughput |
0.479 | High |
|
|
DAPK2
Death-associated protein kinase 2 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
AGO2
Protein argonaute-2 |
1 |
10 |
High-throughput |
0.479 | High |
|
|
AGO1
Protein argonaute-1 |
1 |
10 |
High-throughput |
0.479 | High |
|
|
ASF1A
Histone chaperone ASF1A |
1 |
2 |
High-throughput |
0.479 | High |
|
|
RTCB
RNA-splicing ligase RtcB homolog |
1 |
1 |
High-throughput |
0.479 | High |
|
|
TALDO
Transaldolase |
1 |
0 |
High-throughput |
0.458 | High |
|
|
OAZ1
Ornithine decarboxylase antizyme 1 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
C8AP2
CASP8-associated protein 2 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
NQO1
NAD(P)H dehydrogenase [quinone] 1 |
1 |
1 |
Small-scale |
0.445 | High |
|
|
NPRL3
GATOR1 complex protein NPRL3 |
1 |
3 |
High-throughput |
0.437 | High |
|
|
MTHSD
Methenyltetrahydrofolate synthase domain-containing protein |
1 |
3 |
High-throughput |
0.437 | High |
|
|
SAS6
Spindle assembly abnormal protein 6 homolog |
1 |
4 |
High-throughput |
0.437 | High |
|
|
TRM11
tRNA |
1 |
3 |
High-throughput |
0.437 | High |
|
|
CF206
Cilia- and flagella-associated protein 206 |
1 |
1 |
High-throughput |
0.437 | High |
|
|
DYN3
Dynamin-3 |
1 |
2 |
High-throughput |
0.437 | High |
|
|
XPO1
Exportin-1 |
1 |
2 |
Small-scale |
0.408 | High |
|
|
CF141
Uncharacterized protein C6orf141 |
2 |
0 |
High-throughput |
0.328 | High |
|
|
CF184
Cilia- and flagella-associated protein 184 |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
BORC8
BLOC-1-related complex subunit 8 |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
RBL2A
Rab-like protein 2A |
1 |
0 |
High-throughput |
0.249 | Low |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
