Protein: EDF1
Endothelial differentiation-related factor 1 (EDF-1) (Multiprotein-bridging factor 1) (MBF1)

Gene: EDF1
Organism: Homo sapiens
Interactions: 80
UniProt ID: O60869

Gene Ontology (top 5):
GO:0001094 - TFIID-class transcription factor complex binding
GO:0003677 - DNA binding
GO:0003713 - transcription coactivator activity
GO:0003723 - RNA binding
GO:0005516 - calmodulin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

242977

TBP
TATA-box-binding protein

3

2

Small-scale

0.663

High

242963

ESR1
Estrogen receptor

3

3

Small-scale

0.641

High

242965

JUN
Transcription factor Jun

2

3

Small-scale

0.624

High

242980

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.618

High

242969

TAU
Microtubule-associated protein tau

2

0

High-throughput

0.576

High

242984

PPARG
Peroxisome proliferator-activated receptor gamma

1

3

Small-scale

0.573

High

243004

NR1H3
Oxysterols receptor LXR-alpha

1

3

Small-scale

0.573

High

242989

MEOX2
Homeobox protein MOX-2

1

2

High-throughput

0.573

High

242988

CEBPA
CCAAT/enhancer-binding protein alpha

2

1

Small-scale

0.571

High

130308

NR5A2
Nuclear receptor subfamily 5 group A member 2

1

6

Small-scale

0.561

High

242976

RXRA
Retinoic acid receptor RXR-alpha

1

2

Small-scale

0.561

High

242954

BRD4
Bromodomain-containing protein 4

2

0

High-throughput

0.559

High

243000

H31
Histone H3.1

2

0

High-throughput

0.559

High

242981

MK03
Mitogen-activated protein kinase 3

1

1

High-throughput

0.536

High

242971

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

242957

DUS14
Dual specificity protein phosphatase 14

1

0

High-throughput

0.513

High

242967

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.513

High

242987

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

242995

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

243008

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

243019

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.513

High

243027

G3BP2
Ras GTPase-activating protein-binding protein 2

1

0

High-throughput

0.513

High

243029

MB212
Protein mab-21-like 2

1

0

High-throughput

0.513

High

243009

MK06
Mitogen-activated protein kinase 6

1

2

High-throughput

0.508

High

242955

LRP6
Low-density lipoprotein receptor-related protein 6

1

0

High-throughput

0.493

High

242990

ZN157
Zinc finger protein 157

1

0

High-throughput

0.493

High

243003

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.493

High

243028

DDX52
Probable ATP-dependent RNA helicase DDX52

1

0

High-throughput

0.493

High

242985

HD
Huntingtin

1

0

High-throughput

0.493

High

242991

NRL
Neural retina-specific leucine zipper protein

1

0

Small-scale

0.480

High

242993

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.480

High

242999

UBC9
SUMO-conjugating enzyme UBC9

1

0

Small-scale

0.480

High

125037

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

1

High-throughput

0.479

High

242961

FOS
Protein c-Fos

1

1

Small-scale

0.479

High

242973

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

242975

ATF1
Cyclic AMP-dependent transcription factor ATF-1

1

1

Small-scale

0.479

High

243005

STF1
Steroidogenic factor 1

1

4

Small-scale

0.479

High

243011

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

243022

NANOG
Homeobox protein NANOG

1

2

High-throughput

0.479

High

243002

SOX4
Transcription factor SOX-4

1

0

Small-scale

0.460

High

226018

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

242956

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

242958

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

242959

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

242960

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

242962

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

242964

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

242966

TBB5
Tubulin beta chain

1

0

High-throughput

0.458

High

242970

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

242972

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

242974

PYRG1
CTP synthase 1

1

0

High-throughput

0.458

High

242978

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

242979

FGFR4
Fibroblast growth factor receptor 4

1

0

High-throughput

0.458

High

242982

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

242983

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

242986

GATA4
Transcription factor GATA-4

1

0

High-throughput

0.458

High

242996

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

242997

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

242998

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.458

High

243001

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

243006

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.458

High

243007

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

243010

RC3H1
Roquin-1

1

0

High-throughput

0.458

High

243012

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

243014

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

243015

DPPA4
Developmental pluripotency-associated protein 4

1

0

High-throughput

0.458

High

243016

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

243017

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

243018

BICD2
Protein bicaudal D homolog 2

1

0

High-throughput

0.458

High

243020

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.458

High

243023

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.458

High

243024

ZO2
Tight junction protein ZO-2

1

0

High-throughput

0.458

High

243025

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

243026

TBK1
Serine/threonine-protein kinase TBK1

1

0

High-throughput

0.458

High

243030

RBM8A
RNA-binding protein 8A

1

0

High-throughput

0.458

High

242968

VSIG8
V-set and immunoglobulin domain-containing protein 8

1

0

High-throughput

0.426

High

242992

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.426

High

242994

1433G
14-3-3 protein gamma

1

0

High-throughput

0.426

High

243021

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

243013

SBSN
Suprabasin

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024