Protein: METK
S-adenosylmethionine synthase (AdoMet synthase) (EC 2.5.1.6) (Methionine adenosyltransferase) (MAT)

Gene: METK, Sams
Organism: Drosophila melanogaster
Interactions: 31
UniProt ID: P40320

Gene Ontology (top 5):
GO:0004478 - methionine adenosyltransferase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006556 - S-adenosylmethionine biosynthetic process
GO:0006730 - one-carbon metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

822366

METK
S-adenosylmethionine synthase

2

15

High-throughput

0.767

High

822367

TCPG
T-complex protein 1 subunit gamma

1

2

High-throughput

0.656

High

822370

Q7KVP9
General transcription and DNA repair factor IIH helicase subunit XPD

2

1

High-throughput

0.571

High

822384

FBXW7
F-box/WD repeat-containing protein 7

1

2

High-throughput

0.494

High

631770

GNAS
G protein alpha s subunit

1

0

High-throughput

0.486

High

822374

Q9V3Z4
GH11341p

1

0

High-throughput

0.486

High

654212

DDX6
ATP-dependent RNA helicase me31b

1

3

High-throughput

0.479

High

822385

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

1

High-throughput

0.479

High

822371

AKT1
RAC serine/threonine-protein kinase

1

0

High-throughput

0.458

High

822372

FOXO
Forkhead box protein O

1

0

High-throughput

0.458

High

121768

M9PGE1
Dpr-interacting protein alpha, isoform B

1

2

High-throughput

0.439

High

122030

M9PHD6
Uncharacterized protein, isoform B

1

1

High-throughput

0.439

High

476209

MSRA
Peptide methionine sulfoxide reductase

1

0

High-throughput

0.438

High

822383

Q9VX97
LD13476p

1

1

High-throughput

0.417

High

822387

Q9W4R3
Dpr-interacting protein alpha, isoform A

1

1

High-throughput

0.417

High

822376

Q9VBP6
Succinate-semialdehyde dehydrogenase

1

2

High-throughput

0.407

High

479619

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.265

Low

822369

Q7K569
Glycerol-3-phosphate dehydrogenase

1

0

High-throughput

0.265

Low

822373

Q9V3S7
BcDNA.GH12326

1

0

High-throughput

0.265

Low

822378

Q9VGN4
Sarcomere length short, isoform B

1

0

High-throughput

0.265

Low

822379

Q9VHJ3
Enhancer of variegation 3-9

1

0

High-throughput

0.265

Low

822380

Q9VKS2
GEO11429p1

1

0

High-throughput

0.265

Low

822381

Q9VP67
Dynein regulatory complex subunit 2

1

0

High-throughput

0.265

Low

822382

Q9VS80
FI17864p1

1

0

High-throughput

0.265

Low

822386

Q9W1B5
Glycerol-3-phosphate acyltransferase 4, isoform C

1

0

High-throughput

0.265

Low

356534

O97121
cystathionine gamma-lyase

1

0

High-throughput

0.238

Low

822368

Q7K1Q7
Ribosome assembly factor mrt4

1

0

High-throughput

0.238

Low

822377

Q9VBU0
Uncharacterized protein, isoform A

1

0

High-throughput

0.238

Low

571705

MP20
Muscle-specific protein 20

1

0

High-throughput

0.232

Low

822375

Q9VBN9
RE40275p

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025