Protein: EGR2
E3 SUMO-protein ligase EGR2 (EC 2.3.2.-) (AT591) (E3 SUMO-protein transferase ERG2) (Early growth response protein 2) (EGR-2) (Zinc finger protein Krox-20)

Gene: EGR2
Organism: Homo sapiens
Interactions: 162
UniProt ID: P11161

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

326399

SNAI1
Zinc finger protein SNAI1

3

17

High-throughput

0.861

High

505187

EGR1
Early growth response protein 1

2

19

High-throughput

0.754

High

167130

ZN536
Zinc finger protein 536

1

16

High-throughput

0.618

High

231197

ZEB2
Zinc finger E-box-binding homeobox 2

1

19

High-throughput

0.618

High

260355

ZN217
Zinc finger protein 217

1

17

High-throughput

0.618

High

505186

ZEP1
Zinc finger protein 40

1

20

High-throughput

0.618

High

505190

ZEP2
Transcription factor HIVEP2

1

20

High-throughput

0.618

High

505208

MECOM
Histone-lysine N-methyltransferase MECOM

1

20

High-throughput

0.618

High

505211

EGR3
Early growth response protein 3

1

17

Small-scale

0.618

High

505222

ZFHX3
Zinc finger homeobox protein 3

1

11

High-throughput

0.618

High

505237

ZN746
Zinc finger protein 746

1

20

High-throughput

0.618

High

505249

ZFHX4
Zinc finger homeobox protein 4

1

19

High-throughput

0.618

High

505267

RREB1
Ras-responsive element-binding protein 1

1

19

High-throughput

0.618

High

505278

ZN521
Zinc finger protein 521

1

11

High-throughput

0.618

High

505287

BC11B
B-cell lymphoma/leukemia 11B

1

20

High-throughput

0.618

High

505289

BC11A
B-cell lymphoma/leukemia 11A

1

20

High-throughput

0.618

High

505292

ZN644
Zinc finger protein 644

1

17

High-throughput

0.618

High

505296

PRD16
Histone-lysine N-methyltransferase PRDM16

1

19

High-throughput

0.618

High

505316

ZN148
Zinc finger protein 148

1

19

High-throughput

0.618

High

505317

ZN281
Zinc finger protein 281

1

17

High-throughput

0.618

High

505220

NAB2
NGFI-A-binding protein 2

2

6

Small-scale

0.595

High

125116

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

3

Small-scale

0.573

High

505196

HCFC1
Host cell factor 1

1

2

Small-scale

0.541

High

505257

RB15B
Putative RNA-binding protein 15B

1

4

High-throughput

0.541

High

505205

UBC9
SUMO-conjugating enzyme UBC9

1

3

Small-scale

0.527

High

259019

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

1

0

High-throughput

0.518

High

505293

JUPI2
Jupiter microtubule associated homolog 2

1

0

High-throughput

0.518

High

505311

RIMKB
Beta-citrylglutamate synthase B

1

0

High-throughput

0.518

High

505318

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.518

High

317892

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

6

Small-scale

0.501

High

505299

SRA1
Steroid receptor RNA activator 1

1

1

Small-scale

0.501

High

505308

DNM3L
DNA

1

3

Small-scale

0.501

High

505234

RL7L
Ribosomal protein uL30-like

1

4

High-throughput

0.494

High

505231

MYOME
Myomegalin

1

2

High-throughput

0.481

High

505276

MCRS1
Microspherule protein 1

1

1

High-throughput

0.481

High

131686

BCL9
B-cell CLL/lymphoma 9 protein

1

7

High-throughput

0.479

High

146145

ARI1A
AT-rich interactive domain-containing protein 1A

1

6

High-throughput

0.479

High

152580

KMT2D
Histone-lysine N-methyltransferase 2D

1

10

High-throughput

0.479

High

164178

ZN609
Zinc finger protein 609

1

4

High-throughput

0.479

High

170227

TIF1A
Transcription intermediary factor 1-alpha

1

20

High-throughput

0.479

High

178945

FOXP2
Forkhead box protein P2

1

7

High-throughput

0.479

High

179013

TNC18
Trinucleotide repeat-containing gene 18 protein

1

4

High-throughput

0.479

High

183056

KDM6A
Lysine-specific demethylase 6A

1

5

High-throughput

0.479

High

252898

MITF
Microphthalmia-associated transcription factor

1

2

High-throughput

0.479

High

257444

CREST
Calcium-responsive transactivator

1

20

High-throughput

0.479

High

261384

NCOR1
Nuclear receptor corepressor 1

1

5

High-throughput

0.479

High

321696

WIZ
Protein Wiz

1

19

High-throughput

0.479

High

443119

NFIC
Nuclear factor 1 C-type

1

6

High-throughput

0.479

High

473464

ATX1L
Ataxin-1-like

1

1

High-throughput

0.479

High

505183

CADH1
Cadherin-1

1

4

High-throughput

0.479

High

505184

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

8

High-throughput

0.479

High

505188

ATF3
Cyclic AMP-dependent transcription factor ATF-3

1

7

High-throughput

0.479

High

505189

CADH2
Cadherin-2

1

4

High-throughput

0.479

High

505191

CTNA1
Catenin alpha-1

1

1

High-throughput

0.479

High

505192

CTNB1
Catenin beta-1

1

13

High-throughput

0.479

High

505193

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.479

High

505194

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

8

High-throughput

0.479

High

505195

SMCA2
Probable global transcription activator SNF2L2

1

4

High-throughput

0.479

High

505197

HIRA
Protein HIRA

1

2

High-throughput

0.479

High

505198

ATX1
Ataxin-1

1

1

High-throughput

0.479

High

505199

ATN1
Atrophin-1

1

5

High-throughput

0.479

High

505200

HDAC4
Histone deacetylase 4

1

7

High-throughput

0.479

High

505201

RBM11
Splicing regulator RBM11

1

5

High-throughput

0.479

High

505203

LMO4
LIM domain transcription factor LMO4

1

11

High-throughput

0.479

High

505204

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

505206

SSBP2
Single-stranded DNA-binding protein 2

1

2

High-throughput

0.479

High

505207

FLI1
Friend leukemia integration 1 transcription factor

1

9

High-throughput

0.479

High

505209

TLE1
Transducin-like enhancer protein 1

1

7

High-throughput

0.479

High

505210

TLE3
Transducin-like enhancer protein 3

1

7

High-throughput

0.479

High

505212

TLE5
TLE family member 5

1

6

High-throughput

0.479

High

505214

EP300
Histone acetyltransferase p300

1

15

High-throughput

0.479

High

505215

NFIA
Nuclear factor 1 A-type

1

5

High-throughput

0.479

High

505216

NAB1
NGFI-A-binding protein 1

1

6

High-throughput

0.479

High

505217

NCOA6
Nuclear receptor coactivator 6

1

7

High-throughput

0.479

High

505218

RBBP5
Retinoblastoma-binding protein 5

1

3

High-throughput

0.479

High

505219

NCOA2
Nuclear receptor coactivator 2

1

4

High-throughput

0.479

High

505221

NCOA1
Nuclear receptor coactivator 1

1

3

High-throughput

0.479

High

505224

PCGF3
Polycomb group RING finger protein 3

1

17

High-throughput

0.479

High

505225

ARI4B
AT-rich interactive domain-containing protein 4B

1

7

High-throughput

0.479

High

505227

FILA2
Filaggrin-2

1

9

High-throughput

0.479

High

505228

BCORL
BCL-6 corepressor-like protein 1

1

3

High-throughput

0.479

High

505233

ARID2
AT-rich interactive domain-containing protein 2

1

6

High-throughput

0.479

High

505235

NIPBL
Nipped-B-like protein

1

3

High-throughput

0.479

High

505236

TET2
Methylcytosine dioxygenase TET2

1

3

High-throughput

0.479

High

505238

NFRKB
Nuclear factor related to kappa-B-binding protein

1

4

High-throughput

0.479

High

505239

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

3

High-throughput

0.479

High

505240

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

1

High-throughput

0.479

High

505241

BCOR
BCL-6 corepressor

1

6

High-throughput

0.479

High

505243

UBN2
Ubinuclein-2

1

8

High-throughput

0.479

High

505244

PAXI1
PAX-interacting protein 1

1

5

High-throughput

0.479

High

505245

POGZ
Pogo transposable element with ZNF domain

1

20

High-throughput

0.479

High

505246

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

6

High-throughput

0.479

High

505247

PCGF5
Polycomb group RING finger protein 5

1

14

High-throughput

0.479

High

505250

BCL9L
B-cell CLL/lymphoma 9-like protein

1

8

High-throughput

0.479

High

505252

DTX1
E3 ubiquitin-protein ligase DTX1

1

2

Small-scale

0.479

High

505253

FOXP4
Forkhead box protein P4

1

7

High-throughput

0.479

High

505254

MGAP
MAX gene-associated protein

1

3

High-throughput

0.479

High

505255

HOMEZ
Homeobox and leucine zipper protein Homez

1

8

High-throughput

0.479

High

505258

KMT2C
Histone-lysine N-methyltransferase 2C

1

12

High-throughput

0.479

High

505259

ZMIZ2
Zinc finger MIZ domain-containing protein 2

1

2

High-throughput

0.479

High

505260

ARI1B
AT-rich interactive domain-containing protein 1B

1

11

High-throughput

0.479

High

505261

TET1
Methylcytosine dioxygenase TET1

1

3

High-throughput

0.479

High

505263

MORC4
MORC family CW-type zinc finger protein 4

1

1

High-throughput

0.479

High

505264

PHF10
PHD finger protein 10

1

9

High-throughput

0.479

High

505266

MAML1
Mastermind-like protein 1

1

6

High-throughput

0.479

High

505268

DPF1
Zinc finger protein neuro-d4

1

11

High-throughput

0.479

High

505269

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

505270

CBP
CREB-binding protein

1

20

High-throughput

0.479

High

505271

KAT2B
Histone acetyltransferase KAT2B

1

12

High-throughput

0.479

High

505272

SMRC1
SWI/SNF complex subunit SMARCC1

1

6

High-throughput

0.479

High

505273

ISL2
Insulin gene enhancer protein ISL-2

1

10

High-throughput

0.479

High

505274

PF21A
PHD finger protein 21A

1

20

High-throughput

0.479

High

505275

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

20

High-throughput

0.479

High

505277

ZN462
Zinc finger protein 462

1

14

High-throughput

0.479

High

505279

EP400
E1A-binding protein p400

1

10

High-throughput

0.479

High

505280

TREF1
Transcriptional-regulating factor 1

1

4

High-throughput

0.479

High

505281

PHF12
PHD finger protein 12

1

20

High-throughput

0.479

High

505282

ARI3A
AT-rich interactive domain-containing protein 3A

1

6

High-throughput

0.479

High

505284

PCGF1
Polycomb group RING finger protein 1

1

14

High-throughput

0.479

High

505286

PCGF6
Polycomb group RING finger protein 6

1

6

High-throughput

0.479

High

505291

FOXP1
Forkhead box protein P1

1

5

High-throughput

0.479

High

505300

BRD7
Bromodomain-containing protein 7

1

11

High-throughput

0.479

High

505301

TF7L2
Transcription factor 7-like 2

1

20

High-throughput

0.479

High

505302

BICRA
BRD4-interacting chromatin-remodeling complex-associated protein

1

6

High-throughput

0.479

High

505303

BAHC1
BAH and coiled-coil domain-containing protein 1

1

3

High-throughput

0.479

High

505304

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

4

High-throughput

0.479

High

505305

RERE
Arginine-glutamic acid dipeptide repeats protein

1

5

High-throughput

0.479

High

505306

TRPS1
Zinc finger transcription factor Trps1

1

2

High-throughput

0.479

High

505307

SIX4
Homeobox protein SIX4

1

2

High-throughput

0.479

High

505309

ZN608
Zinc finger protein 608

1

2

High-throughput

0.479

High

505310

INO80
Chromatin-remodeling ATPase INO80

1

5

High-throughput

0.479

High

505312

PRR12
Proline-rich protein 12

1

7

High-throughput

0.479

High

505313

AKP8L
A-kinase anchor protein 8-like

1

1

High-throughput

0.479

High

505314

TRI33
E3 ubiquitin-protein ligase TRIM33

1

20

High-throughput

0.479

High

505315

HDAC5
Histone deacetylase 5

1

6

High-throughput

0.479

High

505319

ARIP4
Helicase ARIP4

1

12

High-throughput

0.479

High

505320

NCOR2
Nuclear receptor corepressor 2

1

6

High-throughput

0.479

High

505321

NCOA3
Nuclear receptor coactivator 3

1

4

High-throughput

0.479

High

505202

DCAF7
DDB1- and CUL4-associated factor 7

1

0

High-throughput

0.458

High

505226

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

0

High-throughput

0.458

High

505230

AHDC1
Transcription factor Gibbin

1

0

High-throughput

0.458

High

505248

LDB1
LIM domain-binding protein 1

1

0

High-throughput

0.458

High

505256

IN80E
INO80 complex subunit E

1

0

High-throughput

0.458

High

505262

KDM2B
Lysine-specific demethylase 2B

1

0

High-throughput

0.458

High

505265

GATD1
GATA zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

505283

PYGO2
Pygopus homolog 2

1

0

High-throughput

0.458

High

505285

PAGR1
PAXIP1-associated glutamate-rich protein 1

1

0

High-throughput

0.458

High

505288

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

1

0

High-throughput

0.458

High

505290

EPC1
Enhancer of polycomb homolog 1

1

0

High-throughput

0.458

High

505294

EAF6
Chromatin modification-related protein MEAF6

1

0

High-throughput

0.458

High

505297

RESF1
Retroelement silencing factor 1

1

0

High-throughput

0.458

High

505213

GOGA2
Golgin subfamily A member 2

1

12

High-throughput

0.439

High

164762

SC16A
Protein transport protein Sec16A

1

3

High-throughput

0.437

High

505223

QSER1
Glutamine and serine-rich protein 1

1

6

High-throughput

0.437

High

505229

PRC2B
Protein PRRC2B

1

7

High-throughput

0.437

High

505232

ZMYM4
Zinc finger MYM-type protein 4

1

17

High-throughput

0.437

High

505242

CO039
Uncharacterized protein C15orf39

1

2

High-throughput

0.437

High

505251

PRSR1
Proline and serine-rich protein 1

1

6

High-throughput

0.437

High

505295

FBRS
Probable fibrosin-1

1

1

High-throughput

0.437

High

505298

FBSL
Fibrosin-1-like protein

1

1

High-throughput

0.437

High

430409

PMGE
Bisphosphoglycerate mutase

1

0

High-throughput

0.282

High

505185

PPA5
Tartrate-resistant acid phosphatase type 5

1

0

High-throughput

0.282

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024