Protein: RUNX2
Runt-related transcription factor 2 (Acute myeloid leukemia 3 protein) (Core-binding factor subunit alpha-1) (CBF-alpha-1) (Oncogene AML-3) (Osteoblast-specific transcription factor 2) (OSF-2) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEA2-alpha A) (PEBP2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit)

Gene: RUNX2
Organism: Mus musculus
Interactions: 64
UniProt ID: Q08775

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

993231

PEBB
Core-binding factor subunit beta

1

8

High-throughput

0.621

High

996452

WWTR1
WW domain-containing transcription regulator protein 1

2

19

Small-scale

0.584

High

996461

SKP2
S-phase kinase-associated protein 2

2

1

Small-scale

0.584

High

976068

MSX2
Homeobox protein MSX-2

1

1

Small-scale

0.561

High

996436

HDAC4
Histone deacetylase 4

1

16

Small-scale

0.515

High

996430

TLE1
Transducin-like enhancer protein 1

1

9

Small-scale

0.501

High

639839

UBF1
Nucleolar transcription factor 1

1

6

Small-scale

0.500

High

527149

RB
Retinoblastoma-associated protein

1

2

High-throughput

0.481

High

996434

RBL2
Retinoblastoma-like protein 2

1

2

High-throughput

0.481

High

956295

TAF1A
TATA box-binding protein-associated factor RNA polymerase I subunit A

1

0

Small-scale

0.479

High

56828

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

11

Small-scale

0.479

High

70917

EP300
Histone acetyltransferase p300

1

8

Small-scale

0.479

High

192237

PHB2
Prohibitin-2

1

1

Small-scale

0.479

High

192366

SMAD6
Mothers against decapentaplegic homolog 6

1

16

Small-scale

0.479

High

193386

SOCS3
Suppressor of cytokine signaling 3

1

3

Small-scale

0.479

High

291887

MEN1
Menin

1

1

Small-scale

0.479

High

603957

TAL1
T-cell acute lymphocytic leukemia protein 1 homolog

1

5

High-throughput

0.479

High

623698

PAX3
Paired box protein Pax-3

1

2

Small-scale

0.479

High

808348

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

11

Small-scale

0.479

High

899099

PSME3
Proteasome activator complex subunit 3

1

1

Small-scale

0.479

High

936606

SMAD1
Mothers against decapentaplegic homolog 1

1

16

Small-scale

0.479

High

936662

NCOA1
Nuclear receptor coactivator 1

1

3

Small-scale

0.479

High

956319

PSME1
Proteasome activator complex subunit 1

1

1

Small-scale

0.479

High

957228

SHC1
SHC-transforming protein 1

1

2

Small-scale

0.479

High

996433

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

3

High-throughput

0.479

High

996437

Q78ZM0
Sorting nexin-3

1

1

Small-scale

0.479

High

996445

FOXP3
Forkhead box protein P3

1

5

Small-scale

0.479

High

996447

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

11

Small-scale

0.479

High

996448

TWST2
Twist-related protein 2

1

6

Small-scale

0.479

High

996450

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

11

Small-scale

0.479

High

996451

RNF6
E3 ubiquitin-protein ligase RNF6

1

2

Small-scale

0.479

High

996455

BRD4
Bromodomain-containing protein 4

1

4

Small-scale

0.479

High

996456

DDX21
Nucleolar RNA helicase 2

1

4

Small-scale

0.479

High

93695

E9Q7C1
Mediator of RNA polymerase II transcription subunit 15

1

0

Small-scale

0.458

High

193520

CSN5
COP9 signalosome complex subunit 5

1

0

Small-scale

0.458

High

223232

DMP1
Dentin matrix acidic phosphoprotein 1

1

0

Small-scale

0.458

High

452301

HMGN2
Non-histone chromosomal protein HMG-17

1

0

Small-scale

0.458

High

501142

OSTP
Osteopontin

1

0

Small-scale

0.458

High

654979

VAV
Proto-oncogene vav

1

0

Small-scale

0.458

High

760444

DYN1
Dynamin-1

1

0

Small-scale

0.458

High

936819

STX4
Syntaxin-4

1

0

Small-scale

0.458

High

953142

OSTCN
Osteocalcin

1

0

Small-scale

0.458

High

996429

KPCD1
Serine/threonine-protein kinase D1

1

0

Small-scale

0.458

High

996431

NUP62
Nuclear pore glycoprotein p62

1

0

Small-scale

0.458

High

996432

MEF2D
Myocyte-specific enhancer factor 2D

1

0

Small-scale

0.458

High

996435

ZN521
Zinc finger protein 521

1

0

Small-scale

0.458

High

996439

APOA5
Apolipoprotein A-V

1

0

Small-scale

0.458

High

996440

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1

0

Small-scale

0.458

High

996441

CAR11
Caspase recruitment domain-containing protein 11

1

0

Small-scale

0.458

High

996442

SATB2
DNA-binding protein SATB2

1

0

Small-scale

0.458

High

996443

WWOX
WW domain-containing oxidoreductase

1

0

Small-scale

0.458

High

996444

VPS36
Vacuolar protein-sorting-associated protein 36

1

0

Small-scale

0.458

High

996446

SNW1
SNW domain-containing protein 1

1

0

Small-scale

0.458

High

996449

MGRN1
E3 ubiquitin-protein ligase MGRN1

1

0

Small-scale

0.458

High

996458

GAB1
GRB2-associated-binding protein 1

1

0

Small-scale

0.458

High

996459

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

Small-scale

0.458

High

996460

NRF1
Nuclear respiratory factor 1

1

0

Small-scale

0.458

High

996462

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

0

Small-scale

0.458

High

984969

TSP3
Thrombospondin-3

1

2

Small-scale

0.437

High

996457

Q9JM08
Histone deacetylase

1

8

Small-scale

0.437

High

192357

NRG3
Pro-neuregulin-3, membrane-bound isoform

1

0

Small-scale

0.249

Low

996438

MOGT2
2-acylglycerol O-acyltransferase 2

1

0

Small-scale

0.249

Low

996453

ACOX3
Peroxisomal acyl-coenzyme A oxidase 3

1

0

Small-scale

0.249

Low

996454

RT29
Small ribosomal subunit protein mS29

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024