Protein: SRP54
Signal recognition particle subunit SRP54 (EC 3.6.5.4) (Signal recognition particle 54 kDa protein)

Gene: SRP54
Organism: Homo sapiens
Interactions: 131
UniProt ID: P61011

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

894986

SRP68
Signal recognition particle subunit SRP68

5

2

Small-scale

0.927

High

894919

SRP54
Signal recognition particle subunit SRP54

1

10

Small-scale

0.710

High

828689

SRP09
Signal recognition particle 9 kDa protein

4

1

Small-scale

0.699

High

447889

SRP19
Signal recognition particle 19 kDa protein

1

3

High-throughput

0.691

High

894995

SRPRB
Signal recognition particle receptor subunit beta

1

7

High-throughput

0.691

High

283449

SRP72
Signal recognition particle subunit SRP72

2

3

High-throughput

0.628

High

503794

HSP7C
Heat shock cognate 71 kDa protein

2

1

High-throughput

0.628

High

894960

GIMA8
GTPase IMAP family member 8

2

0

High-throughput

0.602

High

894923

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.586

High

739672

SRP14
Signal recognition particle 14 kDa protein

2

0

Small-scale

0.585

High

227027

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

894965

LRC59
Leucine-rich repeat-containing protein 59

2

1

High-throughput

0.584

High

894973

DERL1
Derlin-1

2

3

Small-scale

0.584

High

369287

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

180257

MAGB2
Melanoma-associated antigen B2

1

1

High-throughput

0.536

High

403144

LA
Lupus La protein

1

2

High-throughput

0.536

High

508896

TOP2A
DNA topoisomerase 2-alpha

1

1

High-throughput

0.536

High

545795

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

1

High-throughput

0.536

High

643286

HMGB2
High mobility group protein B2

1

1

High-throughput

0.536

High

736337

RL4
Large ribosomal subunit protein uL4

1

2

High-throughput

0.536

High

780645

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

4

High-throughput

0.536

High

805903

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.536

High

849015

SSDH
Succinate-semialdehyde dehydrogenase, mitochondrial

1

1

High-throughput

0.536

High

871522

HSP72
Heat shock-related 70 kDa protein 2

1

2

High-throughput

0.536

High

874475

XPO2
Exportin-2

1

2

High-throughput

0.536

High

894920

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.536

High

894927

RT11
Small ribosomal subunit protein uS11m

1

3

High-throughput

0.536

High

894928

RL19
Large ribosomal subunit protein eL19

1

1

High-throughput

0.536

High

894939

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

High-throughput

0.536

High

894943

CAPR1
Caprin-1

1

1

High-throughput

0.536

High

894962

PSPC1
Paraspeckle component 1

1

1

High-throughput

0.536

High

894972

DNJC2
DnaJ homolog subfamily C member 2

1

2

High-throughput

0.536

High

894981

DUS22
Dual specificity protein phosphatase 22

1

2

High-throughput

0.536

High

894982

STK26
Serine/threonine-protein kinase 26

1

1

High-throughput

0.536

High

894991

G3BP2
Ras GTPase-activating protein-binding protein 2

1

2

High-throughput

0.536

High

323672

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

418095

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

532461

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.513

High

813294

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

817853

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.513

High

830860

CTCF
Transcriptional repressor CTCF

1

0

High-throughput

0.513

High

840894

MAP2
Methionine aminopeptidase 2

1

0

High-throughput

0.513

High

894922

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.513

High

894929

KPCE
Protein kinase C epsilon type

1

0

High-throughput

0.513

High

894932

DHX9
ATP-dependent RNA helicase A

1

0

High-throughput

0.513

High

894940

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.513

High

894944

CND2
Condensin complex subunit 2

1

0

High-throughput

0.513

High

894946

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

894950

C102B
Coiled-coil domain-containing protein 102B

1

0

High-throughput

0.513

High

894952

CPLX2
Complexin-2

1

0

High-throughput

0.513

High

894971

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

894974

MND1
Meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.513

High

894979

DMAP1
DNA methyltransferase 1-associated protein 1

1

0

High-throughput

0.513

High

894989

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.513

High

894992

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.513

High

894994

ATG4B
Cysteine protease ATG4B

1

0

High-throughput

0.513

High

174764

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.501

High

894931

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

0

High-throughput

0.493

High

148599

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

162566

XPO1
Exportin-1

1

2

High-throughput

0.479

High

322401

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

3

High-throughput

0.479

High

346377

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

373975

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

552384

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

569487

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

573646

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

1

High-throughput

0.479

High

650831

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

668558

PML
Protein PML

1

2

High-throughput

0.479

High

785807

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

1

High-throughput

0.479

High

795090

SSRA
Translocon-associated protein subunit alpha

1

1

High-throughput

0.479

High

835296

GSK3A
Glycogen synthase kinase-3 alpha

1

1

High-throughput

0.479

High

835623

GSK3B
Glycogen synthase kinase-3 beta

1

1

High-throughput

0.479

High

838750

EMD
Emerin

1

1

High-throughput

0.479

High

890051

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.479

High

894925

RL31
Large ribosomal subunit protein eL31

1

2

High-throughput

0.479

High

894930

CKAP4
Cytoskeleton-associated protein 4

1

3

High-throughput

0.479

High

894934

STX4
Syntaxin-4

1

2

High-throughput

0.479

High

894937

RFA4
Replication protein A 30 kDa subunit

1

2

High-throughput

0.479

High

894938

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.479

High

894941

STIM1
Stromal interaction molecule 1

1

1

High-throughput

0.479

High

894942

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

2

High-throughput

0.479

High

894945

TRBP2
RISC-loading complex subunit TARBP2

1

3

High-throughput

0.479

High

894948

LARP7
La-related protein 7

1

2

High-throughput

0.479

High

894951

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

894953

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.479

High

894954

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

894959

RN149
E3 ubiquitin-protein ligase RNF149

1

3

High-throughput

0.479

High

894961

GEMI5
Gem-associated protein 5

1

3

Small-scale

0.479

High

894963

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

894967

RN185
E3 ubiquitin-protein ligase RNF185

1

1

Small-scale

0.479

High

894968

DNJC1
DnaJ homolog subfamily C member 1

1

5

High-throughput

0.479

High

894970

SEC62
Translocation protein SEC62

1

1

High-throughput

0.479

High

894976

DERL2
Derlin-2

1

3

Small-scale

0.479

High

894984

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

894987

UBQL2
Ubiquilin-2

1

1

High-throughput

0.479

High

894990

FZR1
Fizzy-related protein homolog

1

2

High-throughput

0.479

High

894996

RBM8A
RNA-binding protein 8A

1

1

High-throughput

0.479

High

125299

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

157721

GEMI2
Gem-associated protein 2

1

0

Small-scale

0.458

High

244196

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

294607

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

344183

A1AT
Alpha-1-antitrypsin

1

0

Small-scale

0.458

High

883962

GEMI4
Gem-associated protein 4

1

0

Small-scale

0.458

High

894921

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

894924

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

894926

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.458

High

894936

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

0

High-throughput

0.458

High

894947

SMN
Survival motor neuron protein

1

0

Small-scale

0.458

High

894957

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

894964

ARHG2
Rho guanine nucleotide exchange factor 2

1

0

Small-scale

0.458

High

894977

DNJC5
DnaJ homolog subfamily C member 5

1

0

High-throughput

0.458

High

894978

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

894985

TES
Testin

1

0

High-throughput

0.458

High

894988

DDX20
Probable ATP-dependent RNA helicase DDX20

1

0

Small-scale

0.458

High

894935

STK4
Serine/threonine-protein kinase 4

1

1

High-throughput

0.445

High

894949

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

384586

NTRK1
High affinity nerve growth factor receptor

1

14

High-throughput

0.437

High

720116

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

894933

DDR1
Epithelial discoidin domain-containing receptor 1

1

13

Small-scale

0.437

High

894956

TM11B
Transmembrane protease serine 11B

1

3

High-throughput

0.437

High

894958

CXD3
Gap junction delta-3 protein

1

2

High-throughput

0.437

High

894969

DERL3
Derlin-3

1

3

Small-scale

0.437

High

894980

TMPS4
Transmembrane protease serine 4

1

3

High-throughput

0.437

High

894983

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.437

High

882206

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.426

High

894955

CFA47
Cilia- and flagella-associated protein 47

1

0

High-throughput

0.426

High

894966

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

831162

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

894993

RT18C
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.279

Low

894975

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024