Protein: MUTYH
Adenine DNA glycosylase (EC 3.2.2.31) (MutY homolog) (hMYH)

Gene: MUTYH
Organism: Homo sapiens
Interactions: 29
UniProt ID: Q9UIF7

Gene Ontology (top 5):
GO:0000701 - purine-specific mismatch base pair DNA N-glycosylase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0006281 - DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

653024

APEX1
DNA repair nuclease/redox regulator APEX1

3

3

Small-scale

0.670

High

794335

MSH2
DNA mismatch repair protein Msh2

2

1

Small-scale

0.629

High

517527

PCNA
Proliferating cell nuclear antigen

2

2

Small-scale

0.624

High

1266892

TOPB1
DNA topoisomerase 2-binding protein 1

2

2

Small-scale

0.624

High

1305393

RAD9A
Cell cycle checkpoint control protein RAD9A

2

2

Small-scale

0.624

High

1192255

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

3

Small-scale

0.578

High

652546

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

Small-scale

0.561

High

855576

MSH6
DNA mismatch repair protein Msh6

1

1

Small-scale

0.561

High

1236557

SIR6
NAD-dependent protein deacylase sirtuin-6

1

2

Small-scale

0.561

High

349713

RASH
GTPase HRas

1

0

High-throughput

0.518

High

612510

XPA
DNA repair protein complementing XP-A cells

1

0

High-throughput

0.518

High

960718

FANCC
Fanconi anemia group C protein

1

0

High-throughput

0.518

High

1048047

CYLC2
Cylicin-2

1

0

High-throughput

0.518

High

1078772

SMAD1
Mothers against decapentaplegic homolog 1

1

0

High-throughput

0.518

High

1355160

DPOLL
DNA polymerase lambda

1

0

Small-scale

0.480

High

245920

HUS1
Checkpoint protein HUS1

1

2

Small-scale

0.479

High

1303020

MMS19
MMS19 nucleotide excision repair protein homolog

1

2

High-throughput

0.479

High

360523

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.460

High

135719

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

0

High-throughput

0.458

High

1038189

ATR
Serine/threonine-protein kinase ATR

1

0

Small-scale

0.458

High

1042790

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1334433

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

1165223

LRSM1
E3 ubiquitin-protein ligase LRSAM1

1

0

High-throughput

0.438

High

1164281

ATRAP
Type-1 angiotensin II receptor-associated protein

1

0

High-throughput

0.299

High

890499

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.282

High

1047991

BAAT
Bile acid-CoA:amino acid N-acyltransferase

1

0

High-throughput

0.282

High

1135036

TSTD2
Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2

1

0

High-throughput

0.282

High

1245989

TDRD7
Tudor domain-containing protein 7

1

0

High-throughput

0.282

High

1292986

MSD3
Myb/SANT-like DNA-binding domain-containing protein 3

1

0

High-throughput

0.282

High


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Last updated: 15 Jul 2024