Protein: CORIN
Atrial natriuretic peptide-converting enzyme (EC 3.4.21.-) (Corin) (Heart-specific serine proteinase ATC2) (Pro-ANP-converting enzyme) (Transmembrane protease serine 10) [Cleaved into: Atrial natriuretic peptide-converting enzyme, N-terminal propeptide; Atrial natriuretic peptide-converting enzyme, activated protease fragment; Atrial natriuretic peptide-converting enzyme, 180 kDa soluble fragment; Atrial natriuretic peptide-converting enzyme, 160 kDa soluble fragment; Atrial natriuretic peptide-converting enzyme, 100 kDa soluble fragment]

Gene: CORIN
Organism: Homo sapiens
Interactions: 5
UniProt ID: Q9Y5Q5

Gene Ontology (top 5):
GO:0003050 - regulation of systemic arterial blood pressure by atrial natriuretic peptide
GO:0004175 - endopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

138586

CLD5
Claudin-5

2

1

High-throughput

0.606

High

932719

EMP1
Epithelial membrane protein 1

2

0

High-throughput

0.580

High

1109102

AQP6
Aquaporin-6

2

1

High-throughput

0.553

High

1352560

GPX8
Probable glutathione peroxidase 8

2

1

High-throughput

0.553

High

1326179

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025