Protein: DHE4
NADP-specific glutamate dehydrogenase 1 (NADP-GDH 1) (EC 1.4.1.4) (NADP-dependent glutamate dehydrogenase 1)

Gene: DHE4, GDH1
Organism: Saccharomyces cerevisiae S288C
Interactions: 109
UniProt ID: P07262

Gene Ontology (top 5):
GO:0004354 - glutamate dehydrogenase (NADP+) activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006537 - glutamate biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

425021

DHE5
NADP-specific glutamate dehydrogenase 2

2

5

High-throughput

0.737

High

424968

DHE4
NADP-specific glutamate dehydrogenase 1

1

5

Small-scale

0.691

High

425031

LSM1
Sm-like protein LSm1

2

1

High-throughput

0.603

High

424994

SIS1
Protein SIS1

2

0

High-throughput

0.576

High

339964

KPYK1
Pyruvate kinase 1

2

1

High-throughput

0.571

High

425030

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

424974

HSP71
Heat shock protein SSA1

2

4

High-throughput

0.552

High

424977

SSB1
Ribosome-associated molecular chaperone SSB1

2

6

High-throughput

0.552

High

425004

HSP7F
Heat shock protein homolog SSE1

2

5

High-throughput

0.552

High

425017

RPN1
26S proteasome regulatory subunit RPN1

2

0

High-throughput

0.547

High

425013

YPT52
GTP-binding protein YPT52

1

2

High-throughput

0.536

High

424970

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.513

High

425006

RAEP
Rab proteins geranylgeranyltransferase component A

1

0

High-throughput

0.513

High

425032

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.513

High

425039

MCE1
mRNA-capping enzyme subunit alpha

1

0

High-throughput

0.513

High

425040

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

412614

KAPA
cAMP-dependent protein kinase type 1

1

1

High-throughput

0.500

High

424969

PBS2
MAP kinase kinase PBS2

1

1

High-throughput

0.500

High

424991

PRP6
Pre-mRNA-splicing factor 6

1

1

High-throughput

0.500

High

424995

RV161
Reduced viability upon starvation protein 161

1

3

High-throughput

0.500

High

425012

VPS21
Vacuolar protein sorting-associated protein 21

1

2

High-throughput

0.500

High

425022

RV167
Reduced viability upon starvation protein 167

1

4

High-throughput

0.500

High

425056

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.500

High

425047

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

1

0

High-throughput

0.493

High

424983

EI2BA
Translation initiation factor eIF2B subunit alpha

1

0

High-throughput

0.479

High

424992

PP11
Serine/threonine-protein phosphatase PP1-1

1

0

High-throughput

0.479

High

424996

DMC1
Meiotic recombination protein DMC1

1

0

High-throughput

0.479

High

424997

GID7
Glucose-induced degradation protein 7

1

0

High-throughput

0.479

High

425015

IMB2
Importin subunit beta-2

1

0

High-throughput

0.479

High

425036

SSK2
MAP kinase kinase kinase SSK2

1

0

High-throughput

0.479

High

334405

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.479

High

342615

ENO1
Enolase 1

1

1

High-throughput

0.479

High

342817

ENO2
Enolase 2

1

1

High-throughput

0.479

High

365579

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.479

High

410853

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.479

High

424972

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

1

Small-scale

0.479

High

424979

SRS2
ATP-dependent DNA helicase SRS2

1

1

High-throughput

0.479

High

424980

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.479

High

424986

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.479

High

424998

CDC48
Cell division control protein 48

1

1

High-throughput

0.479

High

425000

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

425001

TF3B
Transcription factor IIIB 70 kDa subunit

1

2

High-throughput

0.479

High

425002

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

425019

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.479

High

425020

DHH1
ATP-dependent RNA helicase DHH1

1

3

High-throughput

0.479

High

425038

HST2
NAD-dependent protein deacetylase HST2

1

3

High-throughput

0.479

High

425043

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

425046

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.479

High

425051

RRP6
Exosome complex exonuclease RRP6

1

2

High-throughput

0.479

High

425053

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

336650

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.458

High

340580

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.458

High

343329

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

343491

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.458

High

389193

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

406657

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

413207

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

424978

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

424981

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.458

High

424985

TAL1
Transaldolase

1

0

High-throughput

0.458

High

425005

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

425008

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

425011

TCTP
Translationally-controlled tumor protein homolog

1

0

High-throughput

0.458

High

425023

RSP5
E3 ubiquitin-protein ligase RSP5

1

0

High-throughput

0.458

High

425027

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

425029

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.458

High

425033

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

425042

COFI
Cofilin

1

0

High-throughput

0.458

High

425044

YD391
Uncharacterized protein YDR391C

1

0

High-throughput

0.458

High

425049

SGO1
Shugoshin

1

0

High-throughput

0.458

High

425054

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

425055

ENT1
Epsin-1

1

0

High-throughput

0.458

High

425041

UBC7
Ubiquitin-conjugating enzyme E2 7

1

1

High-throughput

0.457

High

333660

ADH1
Alcohol dehydrogenase 1

1

1

High-throughput

0.445

High

367617

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.445

High

424273

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.445

High

424973

IF4A
ATP-dependent RNA helicase eIF4A

1

4

High-throughput

0.445

High

424975

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

424987

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.445

High

425003

EF2
Elongation factor 2

1

2

High-throughput

0.445

High

425009

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

425025

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

425028

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.445

High

425052

HSP42
Heat shock protein 42

1

1

High-throughput

0.445

High

424990

PDI
Protein disulfide-isomerase

1

1

High-throughput

0.437

High

424999

SPB4
ATP-dependent rRNA helicase SPB4

1

2

High-throughput

0.437

High

425014

LONM
Lon protease homolog, mitochondrial

1

3

High-throughput

0.437

High

425016

YB8A
Putative uncharacterized protein YBR285W

1

1

Small-scale

0.437

High

425050

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

360693

TBB
Tubulin beta chain

1

0

High-throughput

0.426

High

424971

TBA3
Tubulin alpha-3 chain

1

0

High-throughput

0.426

High

424976

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.426

High

424984

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.426

High

424988

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

0

High-throughput

0.426

High

424993

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.426

High

425010

GCN1
eIF-2-alpha kinase activator GCN1

1

0

High-throughput

0.426

High

425024

IMB4
Importin subunit beta-4

1

0

High-throughput

0.426

High

425026

PSF2
DNA replication complex GINS protein PSF2

1

0

High-throughput

0.426

High

424989

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.407

High

425018

TOM71
Protein TOM71

1

2

High-throughput

0.407

High

140421

CET1
mRNA-capping enzyme subunit beta

1

0

High-throughput

0.279

Low

425007

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.261

Low

425035

SEH1
Nucleoporin SEH1

1

0

High-throughput

0.261

Low

425037

COPA
Coatomer subunit alpha

1

0

High-throughput

0.261

Low

425045

UTP5
U3 small nucleolar RNA-associated protein 5

1

0

High-throughput

0.261

Low

425034

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

425048

ZEO1
Protein ZEO1

1

0

High-throughput

0.249

Low

424982

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024