Protein: RPB4
DNA-directed RNA polymerase II subunit RPB4 (RNA polymerase II subunit B4) (B32) (DNA-directed RNA polymerase II 32 kDa polypeptide)

Gene: RPB4
Organism: Saccharomyces cerevisiae S288C
Interactions: 84
UniProt ID: P20433

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000932 - P-body
GO:0001172 - RNA-templated transcription
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

593053

RPB7
DNA-directed RNA polymerase II subunit RPB7

30

4

Small-scale

0.992

High

375268

RPB1
DNA-directed RNA polymerase II subunit RPB1

18

8

Small-scale

0.983

High

557863

RPB3
DNA-directed RNA polymerase II subunit RPB3

32

4

Small-scale

0.768

High

593034

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

11

1

Small-scale

0.752

High

593042

RPB9
DNA-directed RNA polymerase II subunit RPB9

9

4

Small-scale

0.749

High

439966

RPB2
DNA-directed RNA polymerase II subunit RPB2

8

3

Small-scale

0.744

High

593035

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

7

1

Small-scale

0.741

High

593036

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

7

1

Small-scale

0.739

High

593063

RPB11
DNA-directed RNA polymerase II subunit RPB11

7

2

Small-scale

0.739

High

593047

MED17
Mediator of RNA polymerase II transcription subunit 17

2

0

Small-scale

0.716

High

593041

SPT5
Transcription elongation factor SPT5

5

1

Small-scale

0.714

High

593037

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

5

1

Small-scale

0.706

High

593073

T2FB
Transcription initiation factor IIF subunit beta

6

0

Small-scale

0.695

High

412652

KAPA
cAMP-dependent protein kinase type 1

1

1

High-throughput

0.691

High

412942

KAPB
cAMP-dependent protein kinase type 2

1

1

High-throughput

0.691

High

593094

IWR1
RNA polymerase II nuclear localization protein IWR1

5

0

Small-scale

0.682

High

593071

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

4

1

Small-scale

0.676

High

593055

TAF14
Transcription initiation factor TFIID subunit 14

5

0

Small-scale

0.676

High

593050

SPT4
Transcription elongation factor SPT4

4

0

Small-scale

0.653

High

593069

RTR1
RNA polymerase II subunit B1 CTD phosphatase RTR1

3

1

Small-scale

0.640

High

593075

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

3

1

Small-scale

0.640

High

581331

MED14
Mediator of RNA polymerase II transcription subunit 14

3

1

Small-scale

0.633

High

593079

NRD1
Protein NRD1

2

1

Small-scale

0.628

High

501314

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

8

Small-scale

0.618

High

593045

EIF3C
Eukaryotic translation initiation factor 3 subunit C

2

0

Small-scale

0.618

High

593072

T2FA
Transcription initiation factor IIF subunit alpha

3

0

Small-scale

0.613

High

593093

ASR1
Alcohol-sensitive RING finger protein 1

3

0

Small-scale

0.613

High

593039

SPT6
Transcription elongation factor SPT6

2

1

Small-scale

0.584

High

593043

TF2B
Transcription initiation factor IIB

2

1

Small-scale

0.584

High

593083

MCE1
mRNA-capping enzyme subunit alpha

2

1

Small-scale

0.584

High

593046

SPT16
FACT complex subunit SPT16

2

0

Small-scale

0.559

High

593082

SEN1
Helicase SEN1

2

0

Small-scale

0.559

High

593080

SUB1
RNA polymerase II transcriptional coactivator SUB1

1

0

Small-scale

0.537

High

593068

RSP5
E3 ubiquitin-protein ligase RSP5

1

3

High-throughput

0.536

High

593040

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

Small-scale

0.529

High

514231

NHP6B
Non-histone chromosomal protein 6B

1

2

Small-scale

0.527

High

593044

XPO1
Exportin-1

1

0

High-throughput

0.513

High

593060

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

0

Small-scale

0.513

High

593074

ELP2
Elongator complex protein 2

1

0

Small-scale

0.513

High

593070

RAD26
DNA repair and recombination protein RAD26

1

1

Small-scale

0.501

High

409946

NOT3
General negative regulator of transcription subunit 3

1

1

Small-scale

0.481

High

514140

NHP6A
Non-histone chromosomal protein 6A

1

2

Small-scale

0.481

High

593097

NOT5
General negative regulator of transcription subunit 5

1

1

Small-scale

0.481

High

593065

POP2
Poly(A) ribonuclease POP2

1

0

Small-scale

0.480

High

593078

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

1

0

Small-scale

0.480

High

355770

H2B2
Histone H2B.2

1

3

High-throughput

0.479

High

425452

TFS2
Transcription elongation factor S-II

1

1

Small-scale

0.479

High

593057

ELF1
Transcription elongation factor 1

1

1

High-throughput

0.479

High

593085

FCP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

3

Small-scale

0.479

High

593086

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.479

High

593088

RT103
Regulator of Ty1 transposition protein 103

1

4

Small-scale

0.479

High

593058

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

0

Small-scale

0.460

High

392285

H2A2
Histone H2A.2

1

0

High-throughput

0.458

High

410073

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

Small-scale

0.458

High

593033

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

Small-scale

0.458

High

593048

MED18
Mediator of RNA polymerase II transcription subunit 18

1

0

Small-scale

0.458

High

593049

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

593051

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

Small-scale

0.458

High

593056

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.458

High

593061

RPP1
Ribonuclease P/MRP protein subunit RPP1

1

0

Small-scale

0.458

High

593064

NAB3
Nuclear polyadenylated RNA-binding protein 3

1

0

Small-scale

0.458

High

593077

RRP46
Exosome complex component RRP46

1

0

Small-scale

0.458

High

593081

H3
Histone H3

1

0

Small-scale

0.458

High

593084

NOP3
Serine/arginine

1

0

Small-scale

0.458

High

593090

YL455
PWWP domain-containing protein YLR455W

1

0

Small-scale

0.458

High

593091

IWS1
Transcription factor SPN1

1

0

High-throughput

0.458

High

593092

CDC73
Cell division control protein 73

1

0

High-throughput

0.458

High

593095

PUF3
mRNA-binding protein PUF3

1

0

Small-scale

0.458

High

593096

NCBP2
Nuclear cap-binding protein subunit 2

1

0

Small-scale

0.458

High

593059

TRM7
tRNA

1

0

High-throughput

0.438

High

593076

THG1
tRNA(His) guanylyltransferase

1

0

High-throughput

0.438

High

593087

POB3
FACT complex subunit POB3

1

1

High-throughput

0.437

High

490306

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

593038

AIM17
Probable oxidoreductase AIM17

2

0

High-throughput

0.307

High

140428

CET1
mRNA-capping enzyme subunit beta

2

0

Small-scale

0.305

High

593089

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

Small-scale

0.303

High

481589

RL18B
Large ribosomal subunit protein eL18B

1

0

High-throughput

0.249

Low

584117

ACON
Aconitate hydratase, mitochondrial

1

0

Small-scale

0.249

Low

593052

PAD1
Flavin prenyltransferase PAD1, mitochondrial

1

0

Small-scale

0.249

Low

593054

SC61G
Protein transport protein SSS1

1

0

Small-scale

0.249

Low

593062

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.249

Low

593066

LAA1
AP-1 accessory protein LAA1

1

0

Small-scale

0.249

Low

593067

RS26B
Small ribosomal subunit protein eS26B

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024