Protein: ASF1
Histone chaperone ASF1 (Anti-silencing function protein 1) (yASF1)

Gene: ASF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 206
UniProt ID: P32447

Gene Ontology (top 5):
GO:0000781 - chromosome, telomeric region
GO:0001932 - regulation of protein phosphorylation
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006282 - regulation of DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

689932

H3
Histone H3

30

18

Small-scale

0.992

High

356323

H4
Histone H4

20

5

Small-scale

0.987

High

689846

HIR1
Protein HIR1

8

18

Small-scale

0.968

High

689972

RT109
Histone acetyltransferase RTT109

5

0

Small-scale

0.882

High

689864

BDF1
Bromodomain-containing factor 1

2

5

Small-scale

0.768

High

689908

HIR3
Histone transcription regulator 3

8

1

Small-scale

0.744

High

689847

HIR2
Protein HIR2

7

16

Small-scale

0.743

High

355826

H2B2
Histone H2B.2

2

1

Small-scale

0.737

High

689995

H2AZ
Histone H2A.Z

2

1

Small-scale

0.737

High

605945

RAD53
Serine/threonine-protein kinase RAD53

22

0

Small-scale

0.734

High

689935

HPC2
Histone promoter control protein 2

5

5

Small-scale

0.703

High

392347

H2A2
Histone H2A.2

2

0

Small-scale

0.699

High

689895

SAS2
Histone acetyltransferase SAS2

3

2

Small-scale

0.674

High

689954

SAS4
Something about silencing protein 4

4

0

Small-scale

0.668

High

689998

SAS5
Something about silencing protein 5

3

2

Small-scale

0.658

High

355395

H2B1
Histone H2B.1

1

1

Small-scale

0.618

High

603285

SNF2
Transcription regulatory protein SNF2

1

10

Small-scale

0.618

High

689861

SPT7
Transcriptional activator SPT7

1

6

Small-scale

0.618

High

689948

GCN5
Histone acetyltransferase GCN5

1

4

Small-scale

0.618

High

689971

BDF2
Bromodomain-containing factor 2

1

5

Small-scale

0.618

High

689989

HIF1
HAT1-interacting factor 1

3

0

Small-scale

0.613

High

456684

RIR2
Ribonucleoside-diphosphate reductase small chain 1

2

1

High-throughput

0.601

High

689910

RIR4
Ribonucleoside-diphosphate reductase small chain 2

2

1

High-throughput

0.601

High

549979

CSK21
Casein kinase II subunit alpha

2

1

High-throughput

0.588

High

584680

CSK22
Casein kinase II subunit alpha'

2

1

High-throughput

0.588

High

689994

RLF2
Chromatin assembly factor 1 subunit p90

2

5

Small-scale

0.585

High

689883

HAT2
Histone acetyltransferase type B subunit 2

2

6

Small-scale

0.584

High

689987

HAT1
Histone acetyltransferase type B catalytic subunit

2

2

Small-scale

0.584

High

689886

RT106
Histone chaperone RTT106

2

0

Small-scale

0.577

High

510596

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.576

High

689893

MAM33
Mitochondrial acidic protein MAM33

2

0

High-throughput

0.576

High

667552

MCM2
DNA replication licensing factor MCM2

1

9

High-throughput

0.575

High

689845

ASF1
Histone chaperone ASF1

1

1

High-throughput

0.575

High

689851

STH1
Nuclear protein STH1/NPS1

1

10

High-throughput

0.575

High

689937

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

9

High-throughput

0.575

High

689967

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

10

High-throughput

0.575

High

689868

TAF5
Transcription initiation factor TFIID subunit 5

2

3

Small-scale

0.571

High

689876

TRA1
Transcription-associated protein 1

2

1

Small-scale

0.571

High

339511

CDK1
Cyclin-dependent kinase 1

2

0

Small-scale

0.569

High

493442

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

526966

TBP
TATA-box-binding protein

2

0

Small-scale

0.547

High

650248

SPT5
Transcription elongation factor SPT5

2

0

Small-scale

0.547

High

689913

TAF6
Transcription initiation factor TFIID subunit 6

2

0

Small-scale

0.547

High

689951

TAF12
Transcription initiation factor TFIID subunit 12

2

0

Small-scale

0.547

High

689980

TAF10
Transcription initiation factor TFIID subunit 10

2

0

Small-scale

0.547

High

689973

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.546

High

689970

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

0

Small-scale

0.537

High

416765

CDC31
Cell division control protein 31

2

1

Small-scale

0.521

High

607229

RFA1
Replication factor A protein 1

1

1

High-throughput

0.515

High

689885

IMB4
Importin subunit beta-4

1

3

Small-scale

0.501

High

689955

CAC2
Chromatin assembly factor 1 subunit p60

1

16

Small-scale

0.501

High

689976

ESA1
Histone acetyltransferase ESA1

1

3

Small-scale

0.501

High

655594

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.493

High

689741

SFP1
Transcription factor SFP1

1

0

High-throughput

0.493

High

689882

RSP5
E3 ubiquitin-protein ligase RSP5

1

0

High-throughput

0.480

High

689945

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

0

High-throughput

0.480

High

661616

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

689871

RFC5
Replication factor C subunit 5

1

3

Small-scale

0.479

High

689873

RFC3
Replication factor C subunit 3

1

3

Small-scale

0.479

High

689874

RFC1
Replication factor C subunit 1

1

4

Small-scale

0.479

High

689887

RFC4
Replication factor C subunit 4

1

4

Small-scale

0.479

High

689888

RFC2
Replication factor C subunit 2

1

3

Small-scale

0.479

High

689896

T2FB
Transcription initiation factor IIF subunit beta

1

1

Small-scale

0.479

High

689901

SAC3
Nuclear mRNA export protein SAC3

1

1

Small-scale

0.479

High

689903

TAF1
Transcription initiation factor TFIID subunit 1

1

1

Small-scale

0.479

High

689905

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

3

Small-scale

0.479

High

689924

BRE5
UBP3-associated protein BRE5

1

1

Small-scale

0.479

High

689936

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

Small-scale

0.479

High

689939

ADA2
Transcriptional adapter 2

1

3

Small-scale

0.479

High

689983

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

1

High-throughput

0.479

High

689984

YRA1
RNA annealing protein YRA1

1

2

Small-scale

0.479

High

420556

SPT2
Protein SPT2

1

0

Small-scale

0.458

High

420597

SPT3
Protein SPT3

1

0

Small-scale

0.458

High

501337

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

0

Small-scale

0.458

High

516853

SIR4
Regulatory protein SIR4

1

0

Small-scale

0.458

High

568860

HPR1
THO complex subunit HPR1

1

0

Small-scale

0.458

High

633835

SGF29
SAGA-associated factor 29

1

0

Small-scale

0.458

High

688147

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

689848

NGG1
Chromatin-remodeling complexes subunit NGG1

1

0

Small-scale

0.458

High

689849

NUP2
Nucleoporin NUP2

1

0

Small-scale

0.458

High

689880

NUP60
Nucleoporin NUP60

1

0

Small-scale

0.458

High

689907

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.458

High

689911

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

Small-scale

0.458

High

689912

SPT20
Transcription factor SPT20

1

0

Small-scale

0.458

High

689918

SGF73
SAGA-associated factor 73

1

0

Small-scale

0.458

High

689926

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

689946

SGF11
SAGA-associated factor 11

1

0

Small-scale

0.458

High

689959

TAF7
Transcription initiation factor TFIID subunit 7

1

0

Small-scale

0.458

High

689961

TAF9
Transcription initiation factor TFIID subunit 9

1

0

Small-scale

0.458

High

689963

RT103
Regulator of Ty1 transposition protein 103

1

0

Small-scale

0.458

High

689968

IWS1
Transcription factor SPN1

1

0

Small-scale

0.458

High

689974

THP1
Nuclear mRNA export protein THP1

1

0

Small-scale

0.458

High

689981

HFI1
Transcriptional coactivator HFI1/ADA1

1

0

Small-scale

0.458

High

689986

SMT3
Ubiquitin-like protein SMT3

1

0

Small-scale

0.458

High

689997

SUS1
Transcription and mRNA export factor SUS1

1

0

Small-scale

0.458

High

472599

YP12B
Transposon Ty1-PR1 Gag-Pol polyprotein

1

1

High-throughput

0.445

High

490628

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

514156

NHP6A
Non-histone chromosomal protein 6A

1

2

High-throughput

0.445

High

577136

SNF5
SWI/SNF chromatin-remodeling complex subunit SNF5

1

1

High-throughput

0.445

High

635488

RSC6
Chromatin structure-remodeling complex protein RSC6

1

1

High-throughput

0.445

High

639255

MSH2
DNA mismatch repair protein MSH2

1

1

High-throughput

0.445

High

663826

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.445

High

687664

BTAF1
TATA-binding protein-associated factor MOT1

1

11

High-throughput

0.445

High

689850

SWI3
SWI/SNF complex subunit SWI3

1

3

High-throughput

0.445

High

689853

CHD1
Chromo domain-containing protein 1

1

6

High-throughput

0.445

High

689856

PDC2
Protein PDC2

1

2

High-throughput

0.445

High

689857

TFC4
Transcription factor tau 131 kDa subunit

1

1

High-throughput

0.445

High

689860

TOR1
Serine/threonine-protein kinase TOR1

1

1

High-throughput

0.445

High

689862

TAF14
Transcription initiation factor TFIID subunit 14

1

2

High-throughput

0.445

High

689869

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

9

High-throughput

0.445

High

689875

RSC30
Chromatin structure-remodeling complex protein RSC30

1

1

High-throughput

0.445

High

689891

ASG1
Activator of stress genes 1

1

1

High-throughput

0.445

High

689899

RSC8
Chromatin structure-remodeling complex protein RSC8

1

3

High-throughput

0.445

High

689914

MCM6
DNA replication licensing factor MCM6

1

12

High-throughput

0.445

High

689915

INO80
Chromatin-remodeling ATPase INO80

1

9

High-throughput

0.445

High

689923

SNF12
Transcription regulatory protein SNF12

1

1

High-throughput

0.445

High

689927

ARP5
Actin-related protein 5

1

1

High-throughput

0.445

High

689928

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.445

High

689930

ORC4
Origin recognition complex subunit 4

1

1

High-throughput

0.445

High

689933

ARP4
Actin-related protein 4

1

2

High-throughput

0.445

High

689943

HOS3
Histone deacetylase HOS3

1

1

High-throughput

0.445

High

689949

NHP10
Non-histone protein 10

1

1

High-throughput

0.445

High

689952

MSH6
DNA mismatch repair protein MSH6

1

1

High-throughput

0.445

High

689953

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.445

High

689960

TRI1
Protein TRI1

1

1

High-throughput

0.445

High

689962

ARP9
Actin-like protein ARP9

1

1

High-throughput

0.445

High

689965

IMB1
Importin subunit beta-1

1

3

High-throughput

0.445

High

689969

RSC3
Chromatin structure-remodeling complex protein RSC3

1

1

High-throughput

0.445

High

689977

UAF30
Upstream activation factor subunit UAF30

1

1

High-throughput

0.445

High

689978

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

10

High-throughput

0.445

High

689990

ARP8
Actin-like protein ARP8

1

1

High-throughput

0.445

High

689991

ARP7
Actin-related protein 7

1

2

High-throughput

0.445

High

689993

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.445

High

140770

FOB1
DNA replication fork-blocking protein FOB1

1

0

High-throughput

0.426

High

365970

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

416205

SIR2
NAD-dependent histone deacetylase SIR2

1

0

High-throughput

0.426

High

419317

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.426

High

419605

RAD52
DNA repair and recombination protein RAD52

1

0

High-throughput

0.426

High

424399

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

425235

PHO2
Regulatory protein PHO2

1

0

High-throughput

0.426

High

519498

PDR1
Transcription factor PDR1

1

0

High-throughput

0.426

High

627808

SIS1
Protein SIS1

1

0

High-throughput

0.426

High

689223

SP110
Spindle pole body component 110

1

0

High-throughput

0.426

High

689854

T2AG
Transcription initiation factor IIA subunit 2

1

0

High-throughput

0.426

High

689855

RSC7
Chromatin structure-remodeling complex subunit RSC7

1

0

High-throughput

0.426

High

689859

SPC29
Spindle pole component 29

1

0

High-throughput

0.426

High

689866

RRN3
RNA polymerase I-specific transcription initiation factor RRN3

1

0

High-throughput

0.426

High

689870

RRN10
RNA polymerase I-specific transcription initiation factor RRN10

1

0

High-throughput

0.426

High

689879

CAJ1
Protein CAJ1

1

0

High-throughput

0.426

High

689884

MIT1
Transcriptional regulator MIT1

1

0

High-throughput

0.426

High

689890

DLS1
Protein DLS1

1

0

High-throughput

0.426

High

689894

MPH1
ATP-dependent DNA helicase MPH1

1

0

High-throughput

0.426

High

689898

IES1
Ino eighty subunit 1

1

0

High-throughput

0.426

High

689902

SUM1
Suppressor of mar1-1 protein

1

0

High-throughput

0.426

High

689916

ITC1
Imitation switch two complex protein 1

1

0

High-throughput

0.426

High

689917

SLD3
DNA replication regulator SLD3

1

0

High-throughput

0.426

High

689919

ENV11
Late endosome and vacuole interface protein 11

1

0

High-throughput

0.426

High

689920

RT102
Regulator of Ty1 transposition protein 102

1

0

High-throughput

0.426

High

689921

RRN9
RNA polymerase I-specific transcription initiation factor RRN9

1

0

High-throughput

0.426

High

689922

H1
Histone H1

1

0

High-throughput

0.426

High

689925

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

689929

ORC3
Origin recognition complex subunit 3

1

0

High-throughput

0.426

High

689931

ACT
Actin

1

0

High-throughput

0.426

High

689934

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.426

High

689940

TBF1
Protein TBF1

1

0

High-throughput

0.426

High

689941

IMA1
Importin subunit alpha

1

0

High-throughput

0.426

High

689944

RRN5
RNA polymerase I-specific transcription initiation factor RRN5

1

0

High-throughput

0.426

High

689947

RSC9
Chromatin structure-remodeling complex subunit RSC9

1

0

High-throughput

0.426

High

689957

DPB4
DNA polymerase epsilon subunit D

1

0

High-throughput

0.426

High

689958

RRN11
RNA polymerase I-specific transcription initiation factor RRN11

1

0

High-throughput

0.426

High

689966

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.426

High

689975

IES4
Ino eighty subunit 4

1

0

High-throughput

0.426

High

689985

RFM1
Repression factor of MSEs protein 1

1

0

High-throughput

0.426

High

689988

IES3
Ino eighty subunit 3

1

0

High-throughput

0.426

High

689992

TFC7
Transcription factor tau 55 kDa subunit

1

0

High-throughput

0.426

High

478004

HSP77
Import motor subunit, mitochondrial

1

1

High-throughput

0.407

High

541648

SEC63
Protein translocation protein SEC63

1

1

High-throughput

0.407

High

689865

LHS1
Heat shock protein 70 homolog LHS1

1

2

High-throughput

0.407

High

689878

CSK2C
Casein kinase II subunit beta'

1

1

High-throughput

0.407

High

689900

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.407

High

689906

NET1
Nucleolar protein NET1

1

1

High-throughput

0.407

High

689938

TOF2
Topoisomerase 1-associated factor 2

1

1

High-throughput

0.407

High

689964

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

3

High-throughput

0.407

High

689979

YP204
Y' element ATP-dependent helicase YPR204W

1

1

High-throughput

0.407

High

420249

CALM
Calmodulin

1

0

High-throughput

0.269

Low

689892

QDR2
Quinidine resistance protein 2

1

0

High-throughput

0.269

Low

689867

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

Small-scale

0.249

Low

689909

NUP57
Nucleoporin NUP57

1

0

Small-scale

0.249

Low

689950

ROT1
Protein ROT1

1

0

High-throughput

0.238

Low

527180

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.232

Low

550166

DPOG
DNA polymerase gamma

1

0

High-throughput

0.232

Low

636039

CSM1
Monopolin complex subunit CSM1

1

0

High-throughput

0.232

Low

689852

ANP1
Mannan polymerase II complex ANP1 subunit

1

0

High-throughput

0.232

Low

689858

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

689863

MNR2
Manganese resistance protein MNR2

1

0

High-throughput

0.232

Low

689872

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

0

High-throughput

0.232

Low

689877

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.232

Low

689881

SNF7
Vacuolar-sorting protein SNF7

1

0

High-throughput

0.232

Low

689889

JEM1
DnaJ-like chaperone JEM1

1

0

High-throughput

0.232

Low

689897

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.232

Low

689904

TFC5
Transcription factor TFIIIB component B''

1

0

High-throughput

0.232

Low

689942

TFB2
General transcription and DNA repair factor IIH subunit TFB2

1

0

High-throughput

0.232

Low

689956

HFD1
Fatty aldehyde dehydrogenase HFD1

1

0

High-throughput

0.232

Low

689982

IOC2
ISWI one complex protein 2

1

0

High-throughput

0.232

Low

689996

CENPS
Inner kinetochore subunit MHF1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024